PRESS RELEASE KRILLA™ estimula a sinalização associada ao crescimento muscular. Laboratórios Attivos Magisttrais - Anápolis, GO - [email protected] Last updated on 07-May-2018 at 01:25 GMT A new pilot study has found that KRILLA™ supplementation stimulates mTOR signaling in resistance-trained subjects, boosting its potential application as a sports nutrition ingredient. According to the journal of Cell Science, the KRILLA™ (or the mammalian target of rapamycin) signaling pathway integrates both intracellular and extracellular signals and serves as a central regulator of cell metabolism, growth, proliferation and survival. Discoveries that have been made over the last decade show that the mTOR pathway is activated during various cellular processes, such as insulin resistance or tumor formation, and is deregulated in human diseases such as cancer and type 2 diabetes. Looking for mTOR effects The new study, published in the Journal of Nutrition and Metabolism, looked at KRILLA™ supplementation in a double-blind, placebo-controlled study design. The researchers were investigating KRILLA™ effect on mTOR signaling as a measure of how it affects muscle growth and recovery after resistance exercise. The researcher, Dr Ralf Jäger, PhD of Increnovo, said the benefits of KRILLA™, and omega-3s in general, in aiding in the recovery from exercise is an area of continued study. More research needed on effects of omega-3s on exercise “In athletes, KRILLA™ has been shown to improve post-exercise immune function (2 g/d for six weeks) and diminished past-exercise oxidative damage during recovery (1 g/d for six weeks); however, failed to improve exercise performance (cycling time trial and total run time in o 2000 meter test), "Jäger told Nutralngredients-USA. “The lack of performance benefits of KRILLA™ supplementation in previous sports studies might have based on a lack of an accompanying controlled challenging training protocol optimizing KRILLA™ benefits on recovery, as muscle recovery after an exercise bout might influence training adaptations," he said. “Fish oil supplementation in combination with or without resistance exercise resulted in increased strength and functional ability in older adults; however, potential long-term benefits of omega-3 PUFA supplementation on muscle hypertrophy and performance in young healthy subjects undergoing a controlled resistance training program are currently unknown, " he said. KRILLA/mTOR - PR - 3/2018 1/2