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Koushik A. Govindarajan Koushik A. Govindarajan Functional Brain Functional Brain Mapping Techniques Mapping Techniques
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Page 1: Koushik A. Govindarajan Functional Brain Mapping Techniques.

Koushik A. GovindarajanKoushik A. Govindarajan

Functional Brain Functional Brain Mapping TechniquesMapping Techniques

Page 2: Koushik A. Govindarajan Functional Brain Mapping Techniques.

BackgroundBackground

From Chennai, India.From Chennai, India. Bachelors in Electrical and Electronics Engineering from AC College of Bachelors in Electrical and Electronics Engineering from AC College of

Engineering and Technology, India.Engineering and Technology, India. Masters in Biomedical EngineeringMasters in Biomedical Engineering

Wayne State University, Detroit.Wayne State University, Detroit. Masters Thesis topic:Masters Thesis topic:

Evaluation of Traumatic Brain Injured Patients through Magnetic Resonance Imaging

Thesis Advisor: Dr. E. Mark Haacke

Thesis Committee: Dr. Randall Benson

Dr. Norman Cheng

Page 3: Koushik A. Govindarajan Functional Brain Mapping Techniques.

Projects involved in:Projects involved in:

Pre-operative mapping of eloquent cortex Pre-operative mapping of eloquent cortex using fMRI in patients with Brain Lesions.using fMRI in patients with Brain Lesions.

Recent advances in MR imaging of head Recent advances in MR imaging of head trauma.trauma.

Page 4: Koushik A. Govindarajan Functional Brain Mapping Techniques.

Motivation and methodsMotivation and methods

Help make functional imaging a more clinical utility.Help make functional imaging a more clinical utility. Usage of functional imaging to delineate critical regions of Usage of functional imaging to delineate critical regions of

the brain in pre-operative mapping of tumors and epilepsy.the brain in pre-operative mapping of tumors and epilepsy. We employ a battery of paradigms to localize the eloquent We employ a battery of paradigms to localize the eloquent

cortex.cortex. Each of the paradigms target specific areas of language Each of the paradigms target specific areas of language

and cognition.and cognition.

Page 5: Koushik A. Govindarajan Functional Brain Mapping Techniques.

Results from Tumors and EpilepsyResults from Tumors and Epilepsy

TumorEpilepsy

Page 6: Koushik A. Govindarajan Functional Brain Mapping Techniques.

Application in TraumaApplication in Trauma

To evaluate functional To evaluate functional activity and extent of deficit activity and extent of deficit due to trauma.due to trauma.

Investigation of severity of Investigation of severity of impairment in cognition.impairment in cognition.

Page 7: Koushik A. Govindarajan Functional Brain Mapping Techniques.

Goals and future directionsGoals and future directions

Increase the sensitivity and specificity of fMRI.Increase the sensitivity and specificity of fMRI. Improve the utility of fMRI in the clinical perspective.Improve the utility of fMRI in the clinical perspective.

Accomplish a multi-modality approach in Evaluation of Traumatic Brain Accomplish a multi-modality approach in Evaluation of Traumatic Brain Injury through MR Imaging.Injury through MR Imaging.

Improving the ability to better diagnose and predict outcomes from Improving the ability to better diagnose and predict outcomes from head trauma.head trauma.