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() ) IT NO \3683/0 \-\ 00908 HHCTPYKQHH no Me.z:tHQHHCKOMY npHMeHeHHIO npenapaTa Pezucmpa/{UOHH6lU HOMep: Topzo6oe HI136aHUe npenapama: Me3iCOYHapooHoe HenameHmo6aHHoe Hll36aHue: HHq,e.z:tHnHH JIe1<apCm6eHHaJI t/JopMa: Ta6JIeTKH, nOKpbITDIe nJIeHO'lHOli 060JIO'lKOli Cocma6: ! Ta6JIeTKa, nOKpDITIUI nJIeHO'lHOli 060JIO'lKoli co.z:teplKHT: AKTHBHoe BemeCTBO: HH«pe.z:tHnHHa ! 0 Mr BcnOMOraTeJIbHbIe BemeCTBa - ma6J1emKa: KapTo«peJIbHbIH KpaxMaJI, lKeRaTHH, JIaKT03a, MHKpOKPHCTaJIJIH'IeCKIUI QeJIJIIOJI03a, MarHHJ! CTeapaT, TaJIbK. - 060JlO'lKa: rnnpoMeJIJI03a, MaKporOJI 6000, JIaK XHHOJIHHOBbIH lKeJITDIH E-! 04, THTaHa ,!IHOKCH.z:t,TaJIbK,npOnHJIeHrJIHKOJIb. OnucaHue Ta6JIeTKH, nOKpDITbIe nJIeHO'lHOli 06oJIo'lKoli, lKeJIToro QBeTa, KpyrJIbIe, .z:tBOliKOBbrnyKllbIe. rpynna: 6JIOKaTOp «Me.z:tJIeHHbIX» KaJIbQHeBbIX KaHaJIOB. KO)J: ATX: C08 CA05 CeJIeKntBHbIit 6JIOKaTOp (Me.z:tJIeHHbIX» KaJILQHeBLIX KaHaJIOB, · npoH3BO,!IHoe ! ,4- - .z:tHrn.z:tponilpH.z:tHHa. OKB3LIBaeT ·BB3o.z:tHJIaTHPYIOIQee, aHTHaHrnHaJIbHOe H rnrroTeH3HBHoe .z:teikTBHe. YMeHLmaeT TOK HOHOB KaJIbQHlI B Kap.z:tHoMHOQHTbI H rJIa,!IKOMDIme'lHbIe KJleTKH KopoHapHbIX H nepH«pepH'IeCKHX apTepHH; B BDICOKHX .z:t03ax no.z:taBJIlIeT BbICB060lK,!leHHe HOHOB KaJILQHlI H3 BHyTpHKJIeTO'lHbIX .z:teno. Y MeHLlIIaeT KOJIH'IeCTBO «PYHKQHOHHPYIOIQHX KaHaJIOB, He OKB3blBlUI B03.z:teHCTBHlI Ha BpeMli HX aKTHBaQHH, HHaKTHBaQHH H BOCCTaHOBJIeHHlI. PB306IQaeT npOQeCCLI B036YlK,!IeHHlI H COKpameHHlI B MHOKap.z:te, onocpe.z:tyeMLIe TponOMH03HHOM H TponOHHHOM, H B rJIa,!IKHX MLllIIQax cocy.z:tOB, onocpe.z:tyeMLle KaJILMO,!lyJIHHOM. B TepaneBTH'IeCKHX .z:t03ax HOPMaJIH3YeT TpaHCMeM6paHHDIH TOK HOHOB KaJILUHlI, HapYlIIeHHLlit npH p".z:te naTOJIOrn'lel:KHX COCTOllHHH, npelK,!le Bcero npH apTepHaJILHOH rHnepTeH3HH. He BJIHlIeT Ha TOHYC BeH. YCHJIHBaeT KopoHapHblit KPOBOTOK, YJIY'llIIaeT KpoBocHa6lKeHHe HlIIeMH3HpOBaHHDIX 30H MHoKap.!la 6e3 pB3BHTHli «peHoMeHa "06Kpa,!lbIBaHHlI", aKTHBHpyeT «PYHKUHoHHpoBaHHe KOJIJIaTepaJIeH. PaclIIHplili nepH«pepH'IeCKHe apTepHH, CHHlKaeT 06IQee nepH«pepH'Iel:Koe cocy,!IHCTOe conpoTHBJIeHHe, TOHYC MHoKap.!la, nOCTHarpPKY, noTpe6HocTb MHoKap.z:ta B KHCJIOpo.z:te H yaeJIH'lHBaeT .z:tJIHTeJIbHOCTb .z:tHaCTOJIH'IeCKoro pacCJIa6JIeHHlI JIeBoro lKeJIy.z:to'lKa (JDK). IIpaKTH'IecKH He BJIHlIeT Ha CHHoaypHKyJIllPHLIH H aTpHOBeHTpHKyJIlIPHLIH Y3JIbl H He 06JIa,!IaeT aHTHapHTMH'IeCKOH aKTHBHOCTblO. Y CHJIHBaeT nO'le'lHDIH KPOBOTOK, Bbl3bIBaeT YMepeHHDIH HaTpHHype3. OTpHuaTeJIbHOe XPOHO-, .z:tPOMO-H HHoTponHoe .z:teHCTBHe
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KOP)J:A~EH® - GastroScan · HH«!>e.l\HnHH MOJKeT BbITeCHlITb H3 CBlI3H C 6enKaMH npenapaTLI, XapaKTepH3Y1OII.{HeCli BblCOKOli CTeneHLIO CB1I3LlBaHHlI (B T.q. HenpliMLle llIITHKOaryJlllHTLI

Aug 13, 2020

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Page 1: KOP)J:A~EH® - GastroScan · HH«!>e.l\HnHH MOJKeT BbITeCHlITb H3 CBlI3H C 6enKaMH npenapaTLI, XapaKTepH3Y1OII.{HeCli BblCOKOli CTeneHLIO CB1I3LlBaHHlI (B T.q. HenpliMLle llIITHKOaryJlllHTLI

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IT NO \3683/0 \-\ 00908

HHCTPYKQHH

no Me.z:tHQHHCKOMY npHMeHeHHIO npenapaTa

KOP)J:A~EH®

Pezucmpa/{UOHH6lU HOMep:

Topzo6oe HI136aHUe npenapama: KOPM~EH®

Me3iCOYHapooHoe HenameHmo6aHHoe Hll36aHue: HHq,e.z:tHnHH

JIe1<apCm6eHHaJI t/JopMa: Ta6JIeTKH, nOKpbITDIe nJIeHO'lHOli 060JIO'lKOli

Cocma6: ! Ta6JIeTKa, nOKpDITIUI nJIeHO'lHOli 060JIO'lKoli co.z:teplKHT:

AKTHBHoe BemeCTBO: HH«pe.z:tHnHHa ! 0 Mr

BcnOMOraTeJIbHbIe BemeCTBa

- ma6J1emKa: KapTo«peJIbHbIH KpaxMaJI, lKeRaTHH, JIaKT03a, MHKpOKPHCTaJIJIH'IeCKIUI

QeJIJIIOJI03a, MarHHJ! CTeapaT, TaJIbK.

- 060JlO'lKa: rnnpoMeJIJI03a, MaKporOJI 6000, JIaK XHHOJIHHOBbIH lKeJITDIH E-! 04, THTaHa

,!IHOKCH.z:t,TaJIbK,npOnHJIeHrJIHKOJIb.

OnucaHue Ta6JIeTKH, nOKpDITbIe nJIeHO'lHOli 06oJIo'lKoli, lKeJIToro QBeTa, KpyrJIbIe, .z:tBOliKOBbrnyKllbIe.

~apMaKOTepaneBTH'Iec'KaH rpynna: 6JIOKaTOp «Me.z:tJIeHHbIX» KaJIbQHeBbIX KaHaJIOB.

KO)J: ATX: C08 CA05

~APMAKO~oruqECKUECBOHCTBA ~apMaKo.z:tHHaMHKa CeJIeKntBHbIit 6JIOKaTOp (Me.z:tJIeHHbIX» KaJILQHeBLIX KaHaJIOB, · npoH3BO,!IHoe ! ,4- -.z:tHrn.z:tponilpH.z:tHHa. OKB3LIBaeT ·BB3o.z:tHJIaTHPYIOIQee, aHTHaHrnHaJIbHOe H rnrroTeH3HBHoe

.z:teikTBHe. YMeHLmaeT TOK HOHOB KaJIbQHlI B Kap.z:tHoMHOQHTbI H rJIa,!IKOMDIme'lHbIe KJleTKH

KopoHapHbIX H nepH«pepH'IeCKHX apTepHH; B BDICOKHX .z:t03ax no.z:taBJIlIeT BbICB060lK,!leHHe

HOHOB KaJILQHlI H3 BHyTpHKJIeTO'lHbIX .z:teno. Y MeHLlIIaeT KOJIH'IeCTBO «PYHKQHOHHPYIOIQHX

KaHaJIOB, He OKB3blBlUI B03.z:teHCTBHlI Ha BpeMli HX aKTHBaQHH, HHaKTHBaQHH H

BOCCTaHOBJIeHHlI. PB306IQaeT npOQeCCLI B036YlK,!IeHHlI H COKpameHHlI B MHOKap.z:te,

onocpe.z:tyeMLIe TponOMH03HHOM H TponOHHHOM, H B rJIa,!IKHX MLllIIQax cocy.z:tOB,

onocpe.z:tyeMLle KaJILMO,!lyJIHHOM. B TepaneBTH'IeCKHX .z:t03ax HOPMaJIH3YeT

TpaHCMeM6paHHDIH TOK HOHOB KaJILUHlI, HapYlIIeHHLlit npH p".z:te naTOJIOrn'lel:KHX COCTOllHHH,

npelK,!le Bcero npH apTepHaJILHOH rHnepTeH3HH. He BJIHlIeT Ha TOHYC BeH. YCHJIHBaeT

KopoHapHblit KPOBOTOK, YJIY'llIIaeT KpoBocHa6lKeHHe HlIIeMH3HpOBaHHDIX 30H MHoKap.!la 6e3

pB3BHTHli «peHoMeHa "06Kpa,!lbIBaHHlI", aKTHBHpyeT «PYHKUHoHHpoBaHHe KOJIJIaTepaJIeH.

PaclIIHplili nepH«pepH'IeCKHe apTepHH, CHHlKaeT 06IQee nepH«pepH'Iel:Koe cocy,!IHCTOe

conpoTHBJIeHHe, TOHYC MHoKap.!la, nOCTHarpPKY, noTpe6HocTb MHoKap.z:ta B KHCJIOpo.z:te H

yaeJIH'lHBaeT .z:tJIHTeJIbHOCTb .z:tHaCTOJIH'IeCKoro pacCJIa6JIeHHlI JIeBoro lKeJIy.z:to'lKa (JDK). IIpaKTH'IecKH He BJIHlIeT Ha CHHoaypHKyJIllPHLIH H aTpHOBeHTpHKyJIlIPHLIH Y3JIbl H He

06JIa,!IaeT aHTHapHTMH'IeCKOH aKTHBHOCTblO. Y CHJIHBaeT nO'le'lHDIH KPOBOTOK, Bbl3bIBaeT

YMepeHHDIH HaTpHHype3. OTpHuaTeJIbHOe XPOHO-, .z:tPOMO-H HHoTponHoe .z:teHCTBHe

Еленаа
Подчеркивание
Еленаа
Подчеркивание
Еленаа
Подчеркивание
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llOKa3aHHH K npHMeHeHHIO

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Page 3: KOP)J:A~EH® - GastroScan · HH«!>e.l\HnHH MOJKeT BbITeCHlITb H3 CBlI3H C 6enKaMH npenapaTLI, XapaKTepH3Y1OII.{HeCli BblCOKOli CTeneHLIO CB1I3LlBaHHlI (B T.q. HenpliMLle llIITHKOaryJlllHTLI

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KpoBH), rnHeKOMaCTHli (y nOJKHJIbIX 60nbHbIX, nOJIHOCThIO HCqe3a1OII.{alI nOCJIe OTMeHbI

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