June 16, 2017 Portland, OR - Bloodworks Northwest · 2018-05-09 · Final Program 2017 June 16, 2017 Portland, OR An education and networking opportunity for Physicians, Nurses, Lab

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Final ProgramFinal ProgramFinal Program

2017

June 16, 2017

Portland, OR

An education and networking opportunity for Physicians,

Nurses, Lab Professionals, and other healthcare professionals

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June 16, 2017 Page 1

Table of Contents

Learning Objectives .......................................................................................................................................................... 2

Accreditation .................................................................................................................................................................... 2

Disclosure Policy ............................................................................................................................................................... 2

Educational Grant ............................................................................................................................................................. 3

Exhibitors .......................................................................................................................................................................... 4

Committee Members ....................................................................................................................................................... 5

Speaker Schedule ............................................................................................................................................................. 6

Presentation Summaries .................................................................................................................................................. 7

Morning Sessions: General Focus ............................................................................................................................. 7

Lunch/Roundtables .................................................................................................................................................. 8

Afternoon Sessions: Medical Focus .......................................................................................................................... 8

Afternoon Sessions: Technical Focus........................................................................................................................ 9

Joint Wrap up Session .............................................................................................................................................. 9

General Information ....................................................................................................................................................... 10

Registration ............................................................................................................................................................ 10

Directions ................................................................................................................................................................ 10

Page 2 301 North Graham – Portland, OR 97227

Learning Objectives

This activity is designed for physicians, nurses, laboratorians, and blood bankers. Upon completion of this course,

participants will be able to:

1. Identify best clinical transfusion practices.

2. Describe updated blood product options.

3. Identify evidenced based transfusion guidelines.

4. Identify updated transfusion laboratory testing practice.

Accreditation

Co-Provided by ASCLS-WA ASCLS‐WA is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program.

Disclosure Policy

In compliance with the ACCME Accreditation Criteria, the American College of Surgeons, as the accredited provider

of this activity, must ensure that anyone in a position to control the content of the educational activity has disclosed all

relevant financial relationships with any commercial interest. All reported conflicts are managed by a designated

official to ensure a bias-free presentation. Please see the insert to this program for the complete disclosure list.

CONTINUING MEDICAL EDUCATION CREDIT INFORMATION

Accreditation This activity has been planned and implemented in accordance with the Essential Areas and Policies of the

Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the American

College of Surgeons and Bloodworks. The American College of Surgeons is accredited by the ACCME to provide

continuing medical education for physicians.

AMA PRA Category 1 Credits™ The American College of Surgeons designates this live activity for a maximum of 7.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Educational Grant

The Bloodworks Northwest Transfusion Symposium

gratefully acknowledges education grant support for this symposium from:

Abbott Laboratories


Exhibitors

The Bloodworks Northwest Transfusion Symposium

gratefully acknowledges exhibit support for this symposium from:

Alexion Pharmaceuticals

Bio-Rad Laboratories

Cerus Corporation

Octapharma USA


Committee Members

2017 Northwest Transfusion Symposium Organizing Committee

YanYun Wu, MD, PhD

Chief Medical Officer, Bloodworks Northwest

Kirsten Alcorn, MD

Medical Director, Bloodworks Northwest

Jackie Degler, MT (ASCP)

Program Manager, Bloodworks Northwest

Bloodworks Northwest Staff Support

Elizabeth Brooke-Willbanks

Brian Danforth

Vida Farhang

Karen Kirby

Jill Klanfer

Sandy Linauts

Cecile Maass

Thom Murray

Sue Nixon

Lisa Thew

Jean Walker

Tony White


Speaker Schedule

Morning Sessions: General Focus Moderator: YanYun Wu, MD, PhD

8:00am - 8:45am Continental Breakfast and Registration

8:45am - 9:00am Welcome Remarks YanYun Wu, MD, PhD

9:00am - 10:00am Maintenance of Tolerance to RBCs: Mechanisms and Challenges

Krystalyn E. Hudson, PhD

10:00am - 11:00am Update on the Use of Low Titer Group A Plasma for Trauma

Nancy M. Dunbar, MD

11:00am - 11:30am Coffee Break and Exhibits

11:30am - 12:30pm Grey Areas: From Transfusion Medicine into Other Clinical Areas

Kirsten Alcorn, MD

David Farris, MD

Lunch: Simultaneous Sessions/Exhibition Moderator: YanYun Wu, MD, PhD

12:30pm - 2:00pm Expert Panel Round Table: From Grey Areas to Your Practical Challenges

YanYun Wu, MD, PhD

Kirsten Alcorn, MD

Ryan Metcalf, MD

Katie Wilkinson, MD

Open Lunch Networking/Exhibits (No CME Credit)

Afternoon Sessions: Medical Focus Moderator: YanYun Wu, MD, PhD

2:00pm - 3:00pm Implementation of 7 day Platelets in a Hospital Transfusion Service

Nancy M. Dunbar, MD

3:00pm - 4:00pm Pathogen Reduction: A Proactive Approach to Blood Product Safety

Jeff Huxford, MMSc

4:00pm - 4:15pm Coffee Break and Exhibits

Afternoon Sessions: Technical Focus Moderator: Kirsten Alcorn, MD

2:00pm - 3:00pm Inventory Management: From Routine to Disaster Planning

Kirsten Alcorn, MD

3:00pm - 4:00pm Blood Bank Danger Zones Theresa Nester, MD

Meghan Delaney, DO, MPH

4:00pm - 4:15 pm Coffee Break and Exhibits

Joint Wrap-up Session Moderator: Kirsten Alcorn, MD

4:15pm - 5:15pm Clinical Case Challenges in Transfusion Medicine (Panel Discussion with Audience Participation)


Kirsten Alcorn, MD

6:00pm Industry Satellite Symposium – No CME Credit

Location: 2448 East Burnside Street, Portland, OR


Presentation Summaries

MORNING SESSIONS: GENERAL FOCUS

Maintenance of Tolerance to RBCs: Mechanisms and Challenges

Krystalyn E. Hudson, PhD

The generation of antibodies (both autoantibodies and alloantibodies) specific to RBC antigens can be a clinically

significant problem and may led to hemolytic reactions, pose barriers to future transfusions and/or transplantations,

and result in hemolytic disease of the fetus and newborn in women of childbearing age. There is currently no accurate

way to predict who will make RBC-specific antibodies. Thus, this session reviews our current research goals and

progress to: 1) elucidate how tolerance to RBC-specific antigens is ascribed (i.e. prevention of autoantibodies);

2) investigate potential pathways involved in breakdown of tolerance thereby leading to autoantibody generation; and

3) identify new risk factors that predispose patients to make alloantibodies to transfused RBCs. Upon completion of

this course, participants will be able to:

1. Review (in general) how tolerance is established in self-antigen.

2. Describe red blood cell (RBC) specific central and peripheral tolerance.

3. Discuss risk factors for RBC alloimmunization.

Update on the Use of Low Titer Group A Plasma for Trauma

Nancy M. Dunbar, MD

Availability of thawed plasma facilitates concurrent provision of plasma and RBCs during trauma resuscitation but can

be challenging due to a limited supply of universally compatible group AB plasma. As an alternative, some centers are

now using emergency issued group A thawed plasma during the initial resuscitation of traumatically injured patients.

This session reviews the data supporting early provision of plasma to traumatically injured patients, the challenges

associated with use of AB plasma for low-volume trauma centers, the rationale for the use of low titer group A plasma,

and the results of a multi-center retrospective study examining the safety of this practice. Upon completion of this

course, participants will be able to:

1. Review coagulation in the setting of traumatic injury and how this influences transfusion practice in the trauma

population.

2. Describe the risks and benefits of using thawed group A plasma for traumatically injured patients of unknown

blood type.

3. Summarize the results of a multi-center retrospective study examining the safety of thawed A plasma in trauma

patients.

Grey Areas: From Transfusion Medicine into Other Clinical Areas

Kirsten Alcorn, MD,

David Farris, MD

Use cases, based on real life scenarios, to highlight issues in blood management as seen from two perspectives: the

transfusion service, and the surgical/anesthesia service. Upon completion of this course, participants will be able to:

1. Use understanding of each area's perspective to improve processes for communication between transfusion

services and operating rooms.

2. Provide leadership for assuring coordinated responses from transfusion service and other labs for patients with

hemorrhagic emergencies.

3. Apply blood management strategies to patients in the operating room and those with massive transfusions.


LUNCH/ROUNDTABLES

Expert Panel Round Table: From Grey Areas to Your Practical Challenges

YanYun Wu, MD, PhD

Kirsten Alcorn, MD

Ryan Metcalf, MD

Katie Wilkinson, MD

This session will discuss challenges faced in a transfusion service such as pathogen reduction, inventory

management, patient blood management, massive transfusion practices, and tough cases. Upon completion of this


1. Prepare and present options for practice updates at home institutions.

2. Recommend and provide implementation options for home institutions.

Open Lunch Networking/Exhibits: No CME

AFTERNOON SESSIONS: MEDICAL FOCUS

Implementation of 7 day platelets in a Hospital Transfusion Service

Nancy M. Dunbar, MD

A pathway currently exists for apheresis platelet outdate extension from 5 to 7 days using an FDA cleared rapid test.

In February 2016, our hospital based transfusion service implemented the use of rapid testing on day 5, 6 and 7 to

extend apheresis platelet shelf life to 7 days. This session describes how to implement 7 day platelets in a hospital

transfusion service and summarizes changes observed in transfusion practice and platelet inventory management

one year following routine use of 7 day platelets at our hospital. Upon completion of this course, participants will be

able to:

1. Describe the use of rapid testing to enhance the safety of platelet transfusion.

2. Review steps necessary for implementation of 7 day platelets using an FDA cleared rapid test.

3. Summarize data illustrating the impact of implementation of 7 day platelets on platelet transfusion patterns and

outdate rates.

Pathogen Reduction: A Proactive Approach to Blood Product Safety

Jeff Huxford, MMSc

This session will review the role of Pathogen Inactivation in the pending FDA draft guidance for the mitigation of

platelet bacterial contamination, discuss a proactive approach to reducing the risk of transfusing emerging pathogens,

and discuss the role of Pathogen Inactivation in addressing the risk of TAGVHD and CMV. Upon completion of this


1. Describe the FDA’s two proposed solutions to mitigating the risk of patients receiving bacterially contaminated

platelets.

2. Gain an appreciation for the type of pathogens that are reduced by the current FDA approved Pathogen

Inactivation System.

3. Understand the FDA’s approach to addressing the Zika epidemic: what role Pathogen Inactivation plays.

4. Describe the AABB’s newest recommendation for reducing the risk of TAGVHD.

5. Describe the Role of Pathogen Inactivation in the mitigation of transfusion risk of CMV.


AFTERNOON SESSIONS: TECHNICAL FOCUS

Inventory Management: From Routine to Disaster Planning

Kirsten Alcorn, MD

The focus of this session is on methods and tools for blood product inventory management, highlighting roles for

different personnel in the transfusion service and interactions with colleagues in other clinical areas. The discussion

will include management of shortages and ideas for managing the blood supply in “disasters,” very special occasions.

Upon completion of this course, participants will be able to:

1. Review inventory management plan and assure all team members are aware of individual roles and involved in

support of the plan.

2. Update routine inventory management processes.

3. Create a process for management of blood product shortages.

4. Create or update emergency operations plan for management of blood inventory.

Blood Bank Danger Zones

Theresa Nester, MD


This session will focus on 3-4 cases that require a heightened awareness or decision-making within the transfusion

service laboratory. Upon completion of this course, participants will be able to:

1. Understand the differential diagnosis and management of rapid, severe hemolytic anemia.

2. Discuss options when the ideal red cell product for pediatric transfusion is unavailable.

3. List a serious infectious potential complication of transfusion and describe the patient populations who may

experience higher morbidity from this complication.

JOINT WRAP UP SESSION

Clinical Case Challenges in Transfusion Medicine (Panel Discussion with Audience Participation)


Kirsten Alcorn, MD

Would you recommend transfusion if the patient is bleeding? What if their hemoglobin is low? How low is low? How

would you transfuse under difficult circumstances? This session discusses cases from the real world that pose

interesting and difficult questions about whether and what to transfuse will be discussed. Audience participation is

encouraged. Upon completion of this course, participants will be able to:

1. Guide transfusion practice at your institution based on the latest published clinical trials and studies.

2. Handle uncommon or emergent transfusion needs, especially when it means deviation from routine practice.


General Information

REGISTRATION

Register early as space is limited:

Online registration: http://2017nwtransfusionsymposium.brownpapertickets.com

On-site registration, if space is available - additional fees apply

Online Registration On-Site Registration

Registration Fees

On or before

June 8, 2017

(Early Bird)

On or before

June 12, 2017

(Regular)

If space is available

Physician/Industry Attendee $150 USD $175 USD $200 USD

Non Physician (Med Tech, RN)/Physician Trainee $75 USD $100 USD $125 USD

Students (with photo ID on site) $40 USD $45 USD $50 USD

Continental breakfast and lunch included in price

For questions, please contact us at

[email protected]

DIRECTIONS

The symposium will take place at:

Lorenzen Conference Center

301 North Graham

Portland, OR 97227

Campus map, directions, and parking information can be found at:

http://www.legacyhealth.org/~/media/Files/PDF/Maps/LegacyEmanuelCampusMap.pdf.

http://2017nwtransfusionsymposium.brownpapertickets.com/

mailto:[email protected]

http://www.legacyhealth.org/~/media/Files/PDF/Maps/LegacyEmanuelCampusMap.pdf

June 16, 2017 Page 11

Notes:


Notes:

June 16, 2017 Portland, OR - Bloodworks Northwest · 2018-05-09 · Final Program 2017 June 16, 2017 Portland, OR An education and networking opportunity for Physicians, Nurses, Lab

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