AgBiome BIO World Congress July 9th, 2019
AgBiomeBIO World Congress
July 9th, 2019
CONFIDENTIAL2Source: Worldometers, UN World Population Prospects
POPULATION REACHING NEW HEIGHTS
IN BILLIONS11.2B
As economies get wealthier,
protein demand increases
CONFIDENTIAL3
FOOD INSECURITY ALREADY A MAJOR ISSUE
Leading to Social InstabilityUndernourished People in the World
821M
Source: FAO, Undernourished are those facing chronic food deprivation.
“The Arab Spring was a revolution of the hungry”
- Boston Globe
CONFIDENTIAL
BASIC CONSTRAINTS FOR FOOD PRODUCTION
4
We need 70% increase in food production by 2050. 2x by 2100
Water
10%
30%Land area on earth
~15B hectares
Available land for food, feed and fiber production~1.5B hectares
2.5% fresh water
<1% is usable
Source: IAEA, FAO
CONFIDENTIAL
DEVASTATING IMPACT OF PESTS AND DISEASE
5Source: Blue River Technology
We lose >20% of crops each year, up to 100% if unprotected
Rapid Spread of Emerging Diseases Resistance to Old Chemicals
Nontreated100% loss
Fungicide treated100% harvested
Powdery Mildew Fungus
CONFIDENTIAL
AGBIOME: LEADING AG INNOVATOR
6
Most advancedand growing pipeline
of traits and biologicalstargeting large markets
Novel microbiome-
based discovery platform to
develop new products
Fastest paceof discovery andtime to market
INVESTORS
InnotechAdvisors
GENESIS™ TECHNOLOGY
7
TrillionsMICROBES
Largest SequencedMicrobe Collection
65,000+
Database Tracks Location, Genome Sequence, Bioassay,
and Field Results
Fully-integrated Systematic, Data-Driven Screening
Process
10,000sStrains
100sGreenhouse
Leads
BIOLOGICALS
DozensFieldLeads
MillionsSingleGenes
1,000sGene
CandidatesTRAITS
Continuous Improvement and Dramatic IP Expansion
CONFIDENTIAL8
Less than 4 years from lab to EPA registered product
• Active on multiple diseases• Organic (OMRI) listed• Pre and post harvest solution
ControlHowler Chemical
>20x MoreEFFECTIVE THAN
CURRENT BIOLOGICALS
COMPARABLETO CHEMICAL
REVOLUTIONARY PRODUCTS: HOWLER™/ZIO™
• Adds to Product Portfolio• Spore-forming microbe, increased formulation
options• Complementary activity increases best-in-industry
efficacy against key disease targets
Complements and Expands Portfolio
Theia™Inoculated CheckHowler™
9
Theia™
CONFIDENTIAL
OPPORTUNITIES FOR SYNTHETIC BIOLOGY IN CROP PROTECTION
10
Improving yield by increasing crop efficiency and production:• Improve photosynthesis efficiency• Improve soil nutrients, water, and CO2 use efficiency• Increase nitrogen fixation by host engineering or microbiome
Maintaining crop yields under abiotic stress:• Minimize change in crop development times expected under higher
temperatures• Reduce heat- and water-stress-response during critical reproductive periods• Reduce transpiration in high temperatures
Maintaining crop yield under biotic stress:• Native or insect or disease resistant traits• Transgenic or wild relatives insect or disease traits• Microbiome engineering
Biosensors
CONFIDENTIAL
MICROBIALDEVELOPMENT PLATFORM
TERRA™Database
MachineLearning
Microbe Collection
EXPANDING OUR FOCUS
11
AGRICULTURE
ANIMAL HEALTH
HUMAN HEALTH
LifeEDIT™
CONFIDENTIAL12
Feed the world, responsibly.
Partner with the microbial world for human benefit.