JOURNAL OF VIROLOGY VOLUME 34 0 NUMBER 3 * JUNE 1980 EDITORIAL BOARD Robert R. Wagner, Editor-in-Chief (1982) University of Virginia School of Medicine, Charlottesville Dwight L. Anderson, Editor (1983) School of Dentistry, University of Minnesota, Minneapolis David T. Denhardt, Editor (1982) McGill University Montreal, Que., Canada Harold S. Ginsberg, Editor (1984) Columbia University New York, N. Y. Edward M. Scolnick, Editor (1982) National Cancer Institute Bethesda, Md. David Baltimore (1981) Amiya K. Banerjee (1982) Kenneth 1. Berns (1982) David H. L. Bishop (1982) David Botstein (1982) Michael A. Bratt (1980) Dennis T. Brown (1981) Ahmad 1. Bukhari (1981) Purnell Chopplin (1980) John M. Coffin (1980) Richard W. Compans (1982) Geoffrey M. Cooper (1981) Nicholas R. Cozzarelli (1980) Clive Dickson (1981) Walter Doerfier (1980) Harrison Echols (1981) Elvera Ehrenfeld (1980) Robert N. Eisenman (1982) Suzanne U. Emerson (1980) Lynn Enquist (1981) Erwin J. Fleissner (1980) S. Jane Flint (1981) Robert M. Friedman (1982) Larry M. Gold (1982) Hidesaburo Hanafusa (1980) William S. Hayward (1981) John J. Holland (1981) Nancy Hopkins (1980) Calderon Howe (1982) Alie S. Huang (1981) D. C. Kely (1982) lTomas J. Kelly, Jr. (1982) George Khoury (1981) Jonathan A. King (1981) David W. Kingsbury (1982) Lloyd M. Kozloff (1982) Robert M. Krug (1980) Robert A. Lazzarini 1981) Richard A. Lerner (1981) Myron Levine (1982) Tomas Lindahl (1981) David M. livingston (1980) Ronald B. Luftig (1981) Robert Martin (1981) Lois K. Miller (1982) Robert C. Miller (1980) Gisela Mosig (1982) Bernard Moss (1980) Joseph S. Pagano (1982) J. Thomas Parsons (1980) Ulf G. Petterson (1980) Lennart Philipson (1981) Peter G. W. Plagemann (1980) Craig R. Pringle (1980) Fred Rapp (1981) Dan S. Ray (1980) M. E. Reichmaan (1982) Bernard E. Reilly (1980) William S. Robinson (1980) Bernard Roizan (1982) Roland R. Rueckert (1982) Norman P. Salzman (1981) Joseph Sambrook (1982) Priscilla A. Schaffer (1981) Sondra Schlesinger (1980) Phillip A. Sharp (1982) Aaron J. Shatkin (1982) Saul J. Silverstein (1982) Lee D. Simon (1981) Kai Simons (1981) Alan E. Smith (1980) Patricia G. Spear (1981) F. Wiliam Studier (1981) Lawrence S. Sturman (1982) Donald F. Summers (1982) William C. Summers (1980) John M. Taylor (1981) Howard M. Temin (1982) David C. Ward (1980) Ernest Winocour (1982) Julius Youngner (1982) Robert A. Day, Managing Editor Gisela Pollock, Assistant Managing Editor Susan Birch, Production Editor 1913 I St., NW, Washington, DC 20006 Willis A. Wood, President (1979-1980) J. Mehsen Joseph, Secretary The Journal of Virology (ISSN 0022-538X), a publication of the American Society for Microbiology, 1913 I St., N.W., Wash- ington, DC 20006, is devoted to the dissemination of fundamental knowledge concerning viruses of bacteria, plants, and animals. Investigators are invited to submit reports of original research in all areas of basic virology, including biochemistry, biophysics, genetics, immunology, morphology, and physiology. Instructions to Authors are published in the January issue each year. The Journal is issued monthly, four volumes per year. The nonmem- ber subscription price is $90 per year; single copies are $8. The member subscription price is $21 per year. Correspondence relating to subscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submitted manu- scripts, and general editorial matters should be directed to the ASM Publications Office, 1913 I St., N.W., Washington, DC 20006 (area 202 833-9680). a * : id M.' ,r it A,J" L ,J Mf( X;s JO I i'ff EX OFFICIO Albert Balows, President-Elect (1979-1980) Brinton M. Miller, Treasurer Second-class postage paid at Washington, DC 20006, and at additional mailing offices. Made in the U.S.A. Copyright X 1980, American Society for Microbiology. All Rights Reserved. The code at the top of the first page of an article in this journal indicates the copyright owner's consent that copies of the article may be made for personal use, or for personal use of specific clients. This consent is given on the condition, however, that the copier pay the stated per-copy fee through the Copyright Clear- ance Center, Inc., P.O. Box 765, Schenectady, New York 12301, for copying beyond that permitted by Sections 107 and 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works, or for resale.
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JOURNAL OF VIROLOGYVOLUME 34 0 NUMBER 3 * JUNE 1980
EDITORIAL BOARDRobert R. Wagner, Editor-in-Chief (1982)University of Virginia School of Medicine,
Charlottesville
Dwight L. Anderson, Editor (1983)School of Dentistry,
University of Minnesota,Minneapolis
David T. Denhardt, Editor (1982)McGill University
Montreal, Que., Canada
Harold S. Ginsberg, Editor (1984)Columbia UniversityNew York, N. Y.
Edward M. Scolnick, Editor (1982)National Cancer Institute
Bethesda, Md.
David Baltimore (1981)Amiya K. Banerjee (1982)Kenneth 1. Berns (1982)David H. L. Bishop (1982)David Botstein (1982)Michael A. Bratt (1980)Dennis T. Brown (1981)Ahmad 1. Bukhari (1981)Purnell Chopplin (1980)John M. Coffin (1980)Richard W. Compans (1982)Geoffrey M. Cooper (1981)Nicholas R. Cozzarelli (1980)Clive Dickson (1981)Walter Doerfier (1980)Harrison Echols (1981)Elvera Ehrenfeld (1980)Robert N. Eisenman (1982)Suzanne U. Emerson (1980)Lynn Enquist (1981)Erwin J. Fleissner (1980)S. Jane Flint (1981)Robert M. Friedman (1982)Larry M. Gold (1982)Hidesaburo Hanafusa (1980)William S. Hayward (1981)John J. Holland (1981)
Nancy Hopkins (1980)Calderon Howe (1982)Alie S. Huang (1981)D. C. Kely (1982)lTomas J. Kelly, Jr. (1982)George Khoury (1981)Jonathan A. King (1981)David W. Kingsbury (1982)Lloyd M. Kozloff (1982)Robert M. Krug (1980)Robert A. Lazzarini 1981)Richard A. Lerner (1981)Myron Levine (1982)Tomas Lindahl (1981)David M. livingston (1980)Ronald B. Luftig (1981)Robert Martin (1981)Lois K. Miller (1982)Robert C. Miller (1980)Gisela Mosig (1982)Bernard Moss (1980)Joseph S. Pagano (1982)J. Thomas Parsons (1980)Ulf G. Petterson (1980)Lennart Philipson (1981)Peter G. W. Plagemann (1980)Craig R. Pringle (1980)
Fred Rapp (1981)Dan S. Ray (1980)M. E. Reichmaan (1982)Bernard E. Reilly (1980)William S. Robinson (1980)Bernard Roizan (1982)Roland R. Rueckert (1982)Norman P. Salzman (1981)Joseph Sambrook (1982)Priscilla A. Schaffer (1981)Sondra Schlesinger (1980)Phillip A. Sharp (1982)Aaron J. Shatkin (1982)Saul J. Silverstein (1982)Lee D. Simon (1981)Kai Simons (1981)Alan E. Smith (1980)Patricia G. Spear (1981)F. Wiliam Studier (1981)Lawrence S. Sturman (1982)Donald F. Summers (1982)William C. Summers (1980)John M. Taylor (1981)Howard M. Temin (1982)David C. Ward (1980)Ernest Winocour (1982)Julius Youngner (1982)
Robert A. Day, Managing EditorGisela Pollock, Assistant Managing Editor
Susan Birch, Production Editor1913 I St., NW, Washington, DC 20006
Willis A. Wood, President (1979-1980)J. Mehsen Joseph, Secretary
The Journal of Virology (ISSN 0022-538X), a publication ofthe American Society for Microbiology, 1913 I St., N.W., Wash-ington, DC 20006, is devoted to the dissemination of fundamentalknowledge concerning viruses of bacteria, plants, and animals.Investigators are invited to submit reports of original research inall areas of basic virology, including biochemistry, biophysics,genetics, immunology, morphology, and physiology. Instructionsto Authors are published in the January issue each year. TheJournal is issued monthly, four volumes per year. The nonmem-ber subscription price is $90 per year; single copies are $8. Themember subscription price is $21 per year. Correspondencerelating to subscriptions, reprints, defective copies, availability ofback issues, lost or late proofs, disposition of submitted manu-scripts, and general editorial matters should be directed to theASM Publications Office, 1913 I St., N.W., Washington, DC20006 (area 202 833-9680).
a * : id M.',r it A,J" L ,J Mf(X;sJO Ii'ff
EX OFFICIOAlbert Balows, President-Elect (1979-1980)
Brinton M. Miller, Treasurer
Second-class postage paid at Washington, DC 20006, and atadditional mailing offices.Made in the U.S.A.Copyright X 1980, American Society for Microbiology.All Rights Reserved.
The code at the top of the first page of an article in this journalindicates the copyright owner's consent that copies of the articlemay be made for personal use, or for personal use of specificclients. This consent is given on the condition, however, that thecopier pay the stated per-copy fee through the Copyright Clear-ance Center, Inc., P.O. Box 765, Schenectady, New York 12301,for copying beyond that permitted by Sections 107 and 108 ofthe U.S. Copyright Law. This consent does not extend to otherkinds of copying, such as copying for general distribution, foradvertising or promotional purposes, for creating new collectiveworks, or for resale.
Author IndexArthur, Larry O., 635
Basilico, Claudio, 615Bishop, D. H. L., 792Brown, F., 792Brown, Fred, 627Buchan, A., 716Burand, John P., 693Bussereau, Francoise, 777
Garro, Anthony J., 789Gattoni, Sebastiano, 615Genty, Nicole, 777Gilden, Raymond V., 743Goldman, Neil, 658Gonda, Matthew A., 743Gorman, Barry M., 583Gurney, Elizabeth G., 752
Halliburton, I. W., 716
Handa, Hiroshi, 592Harris, Timothy J. R., 627Harrison, Robert O., 752Hatanaka, M., 684Hidaka, Hideyuki, 675Hizi, Amnon, 795Holland, J. J., 792Honess, R. W., 716Huang, A. S., 792
Kang, C.-Y., 792Kawai, Sadaaki, 772Kennedy, S. Ian T., 665Khoury, George, 658King, Andrew M. Q., 627Kit, S., 782Klaiber, Rosemarie, 604Knell, John D., 693Kominami, R., 684
Lazzarini, R., 792Leone, Arturo, 598
Mansbridge, Jonathan N., 583Martin, Malcolm A., 650Massey, Richard J., 635Millette, Robert L., 604Misumi, Hiromas7a, 675Mora, Peter T., 650Moyer, S., 792
Naeve, Clayton W., 764Nowinski, Robert C., 635
Oda, Takuzo, 675Otsuka, H., 782
Perrault, J., 792Pincus, Theodore, 711Pontarelli, Gianfranco, 598Prevec, L., 792Pringle, C. R., 792
Rapp, Fred, 704Reichmann, M. E., 792Rice, Nancy R., 743
Sangar, David V., 627Schaffer, Priscilla A., 704Schochetman, Gerald, 635Scriba, Marianne, 644Sharp, Philip A., 592Simmons, Daniel T., 650Smith, Gale E., 693Stern, David F., 665Summers, Donald F., 764Summers, Max D., 693
Tomita, Y., 684Turner, Nancy, 704
Wagner, R. R., 792Walker, Peter J., 583Watson, D. H., 716
Yaniv, Abraham, 795Youngner, J. S., 792
AUTHOR INDEX
VOLUME 34
Ahmed, Rafi, 285, 383Albin, Catherine, 297Allen, George P., 474Amemiga, Kei, 542Anderson, Kevin P., 9Arlinghaus, Ralph B., 464Arthur, Larry O., 635
Bacheler, Lee, 373Bailey, T. J., 360Baluda, M. A., 288, 366Barnett, Bill B., 272Barnett, John M., 474Basilico, Claudio, 615Baucke, Robert B., 512Bauer, Georg, 168Beaudreau, G. S., 360Becker, R. R., 360Bekesi, J. George, 225B6nicourt, Claude, 85Berget, Peter B., 234Bergmann, D. G., 366Berns, K. I., 402Bishop, D. H. L., 792Boiron, Michel, 576Bolen, Joseph B., 119Bose, Henry R., Jr., 484Boyle, Stephen M., 266Breindl, Michael, 373Brian, David A., 410Brown, Donna, 576Brown, F., 792Brown, Fred, 627Buchan, A., 716Burand, John P., 693Burness, Alfred T. H., 266Bussereau, Francoise, 777
Callahan, Robert, 576Cancedda, Ranieri, 598Chakraborty, P. R., 285, 383Chang, Chungning, 650Chroboczek, Jadwiga, 330Clark, Scott M., 272Cohen, Gary H., 142, 521Cohen, Maurice, 28Colantuoni, Vittorio, 598, 615Colby, Brenda M., 560Compans, Richarl W., 154Connors, E. C., 684Consigli, Richard A., 119Costa, Robert H., 9Courtney, R. J., 336Crawford, Lionel V., 315Crick, J., 792Cully, Doris F., 789
Davidson, Norman, 28Denhardt, David T., 315Dennis, Douglas E., 410Diggelmann, Heidi, 521Dorsch-Hasler, Karoline, 305Dubbs, D. R., 782Dutko, Frank J., 256
Famulari, Nancy G., 154Fan, Hung, 373Farrell, Michael P., 455Fedele, Louis A., 200Feighny, Robert J., 455Fenno, James, 752Fields, B. N., 285, 383Fife, K. H., 402Fisher, Paul B., 305Flores, L., 244Fong, Bessie S., 644Fox, C. Fred, 268
Garcette, Marylene, 576Garro, Anthony J., 789Gattoni, Sebastiano, 615Gentry, Glenn A., 474Genty, Nicole, 777Gilden, Raymond V., 28, 743Ginsberg, Harold S., 305Goldman, Neil, 658Gonda, Matthew A., 743Gorman, Barry M., 583Graham, A. F., 383Guntaka, Ramareddy V., 569Gupta, Sohan L., 446Gurney, Elizabeth G., 752Guy, James S., 410
Halliburton, I. W., 716Handa, Hiroshi, 592Hansen, Joanna, 576Harlow, Ed, 213Harris, Timothy J. R., 627Harrison, Robert O., 752Haseltine, William A., 390Hatanaka, M., 684Hattman, Stanley, 277Herman, Ronald C., 550Hidaka, Hideyuki, 675Hill, Diana F., 40Hinkle, David C., 136Hizi, Amnon, 795
Hojman-Montes-De-Oca, Frida,576
Holland, J. J., 792Holland, John J., 256Holland, Louis E., 9Holowczak, John A., 244Honess, R. W., 716Huang, A. S., 792
Inciarte, Marta R., 187
Jaenisch, Rudolph, 373
Kaesberg, Paul, 51Kang, C. Yong, 484Kang, C.-Y., 792Kao, Shao-hui, 95, 104Katz, Richard, 569Kaverin, N. V., 506Kawai, Sadaaki, 772Keene, Jack D., 550Kemp, Maurice C., 154Kennedy, S. Ian T., 256, 665Khoury, George, 658King, Andrew M. Q., 59, 67, 627King, Norval W., Jr., 225Kit, S., 782Klaiber, Rosemarie, 604Knell, John D., 693Kolomietz, L. I., 506Kominami, R., 684
Lampert, Peter W., 256Lawrence, William C., 521Lazzarini, R., 792Lazzarini, Robert A., 550Leone, Arturo, 598Lewis, Hilary A., 354Lewis, Robert B., 484Li, Joseph K.-K., 268Lusby, E., 402
Machtiger, N. A., 336Maizel, Jacob, 200Maltman, K. L., 347, 354Mansbridge, Jonathan N., 583Martin, G. Steven, 280Martin, Malcolm A., 650Massey, Richard J., 635McAllister, Robert M., 28McCahon, David, 67McClain, William H., 95, 104McCormick, Frank, 213McGowan, John J., 474Millette, Robert L., 604Millward, Stewart, 490, 497
ii AUTHOR INDEX
Minor, Philip D., 73Misumi, Hiromasa, 675Mitsialis, S. Alex, 569Miyakawa, Tokichi, 268Mora, Peter T., 650Morch, Marie-Dominique, 85Mosser, Anne G., 431Moyer, S., 792Murphy, Edwin C., Jr., 464Murthy, K. K., 130
Naeve, Clayton W., 764Nakada, Dai, 438Nakajima, K., 1Neiman, Paul, 178Neuhard, Jan, 347, 354Newman, John W. I., 59, 67Nicolson, Margery O., 28Nomura, Nobuo, 162Nowinski, Robert C., 635Nuss, Donald L., 532
Oda, Takuzo, 675O'Donnell, Paul V., 154Oldstone, Michael B. A., 256Ontell, Martin P., 438Oskarsson, Marianne, 200Otsuka, H., 782
Pagano, Joseph S., 455, 560Pancake, B. A., 336Para, Michael F., 512Pawson, Tony, 280Payne, L. N., 178Peries, Jorge, 576Perrault, J., 792Petersen, George B., 40Peterson, Andrew J., 532Pincus, Theodore, 711Pizer, Lewis I., 142Ponce de Leon, Manuel, 521Pontarelli, Gianfranco, 598
Poteete, Anthony R., 234Prevec, L., 792Pringle, C. R., 792Puchkova, Ludmita, 330
Raboy, Bilha, 542Ramabhadran, Triprayar V., 293Ramig, R. F., 383Rao, Prasad Y., 569Rapp, Fred, 704Ray, Dan S., 162Reichmann, M. E., 792Rice, Nancy, 28Rice, Nancy R., 743Robert, Jacqueline, 576Robinson, William S., 297Rohrmann, G. F., 360Rubin, Berish Y., 446Rudneva, I. A., 506Rueckert, Roland R., 431Rutgers, Tineke, 51
Sahagan, Barbara G., 390Salas, Margarita, 187Salemo-Rife, Terry, 51Sangar, David V., 627Sawicki, Dorothea L., 108Sawicki, Stanley G., 108Schaffer, P. A., 336Schaffer, Priscilla A., 704Schat, K. A., 130Schochetman, Gerald, 635Schubert, Manfred, 550Scriba, Marianne, 644Shapiro, Lucille, 542Sharp, Philip A., 592Shaw, James E., 560Shealy, David J., 431Sheppard, Sarah L., 266Sherr, Charles J., 200Shure, Mavis, 28Simmons, Daniel T., 650Skup, Danial, 490, 497
Slade, William R., 67Smith, Gale E., 693Sogo, Jose M., 187Souza, L. M., 366Spear, Patricia G., 512Spendlove, Rex S., 272Srivatsan, E. S., 288Stern, David F., 665Sugiura, A., 1Summers, Donald F., 764Summers, Max D., 693
Temin, Howard M., 168Tevethia, S. S., 336Thach, Robert E., 293Thomas, V., 244Tishon, Antoinette, 256Tomita, Y., 684Turner, Nancy, 704
Ueda, M., 1
Vande Woude, George, 200Vernon, Steven K., 521
Wagner, Edward K., 9Wagner, R. R., 792Walker, Peter J., 583Warren, R. A. J., 347,354Watson, D. H., 716Weinstein, I. Bernard, 305Weiss, Robin A., 178Wills, Norma, 464Wong, Timothy C., 484Wu, Ray, 416
Yagi, Mary Jane, 225Yang, Robert C. A., 416Yaniv, Abraham, 795Young, Alex, 416Youngner, J. S., 792
biochemical transformation, 704imrmunoglobulin G(Fc)-binding receptors, 512recombination and linkage, 716RNA characterization in absence of de novo protein
synthesis, 9structural and regulatory genes, 716ts mutants, 704
chemical carcinogen effect, 305von Magnus particles
extra RNAs, 1influenza virus, 1polymerase gene reduction, 1
Woolly monkey-gibbon ape leukemia viruseshuman leukemia tissues, 390
Wound tumor virusgene product expression in vivo and in vitro, 532
XC cellsavian sarcoma proviral DNA sequence modification,
569nonpermissive, 569
INDEX TO DATE OF ISSUE
Month Date of Issue Pages
April 24 April 1980 1-303May 14 May 1980 305-582June 4 June 1980 583-802
JOURNALOF
VIROLOGY
VOLUME 34
WASHINGTON, DC 20006
1980
JOURNAL OF VIROLOGYVOLUME 34 0 1980
EDITORIAL BOARDRobert R. Wagner, Editor-in-Chief (1982)University of Virginia School of Medicine,
Charlottesville
Dwight L. Anderson, Editor (1983)School of Dentistry,
University of Minnesota,Minneapolis
David T. Denhardt, Editor (1982)McGill University
Montreal, Que., Canada
Harold S. Ginsberg, Editor (1984)Columbia UniversityNew York, N. Y.
Edward M. Scolnick, Editor (1982)National Cancer Institute
Bethesda, Md.
David Baltimore (1981)Amiya K. Banerjee (1982)Kenneth 1. Berns (1982)David H. L. Bisbop (1982)David Botstein (1982)Micbael A. Bratt (1980)Dennis T. Brown (1981)Ahmad 1. Bukhari (1981)Purnell Chopplin (1980)John M. Coffin (1980)Richard W. Compans (1982)Geoffrey M. Cooper (1981)Nicbolas R. Cozzarelli (1980)Clive Dickson (1981)Walter Doerfier (1980)Harrison Echols (1981)Elvera Ehrenfeld (1980)Robert N. Eisenman (1982)Suzanne U. Emerson (1980)Lynn Enquist (1981)Erwin J. Fleissner (1980)S. Jane Flint (1981)Robert M. Friedman (1982)Larry M. Gold (1982)Hidesaburo Hanafusa (1980)William S. Hayward (1981)John J. Holland (1981)
Nancy Hopkins (1980)Calderon Howe (1982)Alice S. Huang (1981)D. C. KeDy (1982)Thomas J. Kelly, Jr. (1982)George Khoury (1981)Jonathan A. King (1981)David W. Kingsbury (1982)Lloyd M. Kozloff (1982)Robert M. Krug (1980)Robert A. Lazzarini 1981)Richard A. Lerner (1981)Myron Levine (1982)Tomas Lindahl (1981)David M. Livingston (1980)Ronald B. Luftig (1981)Robert Martin (1981)Lois K. Mlfler (1982)Robert C. Miller (1980)Gisela Mosig (1982)Bernard Moss (1980)Joseph S. Pagano (1982)J. Thomas Parsons (1980)Ulf G. Petterson (1980)Lennart Philipson (1981)Peter G. W. Plagemann (1980)Craig R. Pringle (1980)
Fred Rapp (1981)Dan S. Ray (1980)M. E. Reichmann (1982)Bernard E. Reilly (1980)William S. Robinson (1980)Bernard Roizman (1982)Roland R. Rueckert (1982)Norman P. Salzman (1981)Joseph Sambrook (1982)Priscilla A. Schaffer (1981)Sondra Schlesinger (1980)Phillip A. Sharp (1982)Aaron J. Shatkin (1982)Saul J. Silverstein (1982)Lee D. Simon (1981)Kai Simons (1981)Alan E. Smith (1980)Patricia G. Spear (1981)F. William Studier (1981)Lawrence S. Sturman (1982)Donald F. Summers (1982)William C. Summers (1980)John M. Taylor (1981)Howard M. Temin (1982)David C. Ward (1980)Ernest Winocour (1982)Julius Youngner (1982)
Robert A. Day, Managing EditorGisella Pollock, Assistant Managing Editor
Susan Birch, Production Editor1913 I St., NW, Washington, DC 20006
Willis A. Wood, President (1979-1980)J. Mehsen Joseph, Secretary
The Journal of Virology (ISSN 0022-538X), a publication ofthe American Society for Microbiology, 1913 I St., N.W., Wash-ington, DC 20006, is devoted to the dissemination offundamentalknowledge concerning viruses of bacteria, plants, and animals.Investigators are invited to submit reports of original research inall areas of basic virology, including biochemistry, biophysics,genetics, immunology, morphology, and physiology. Instructionsto Authors are published in the January issue each year. TheJournal is issued monthly, four volumes per year. The nonmem-ber subscription price is $90 per year; single copies are $8. Themember subscription price is $21 per year. Correspondencerelating to subscriptions, reprints, defective copies, availability ofback issues, lost or late proofs, disposition of submitted manu-scripts, and general editorial matters should be directed to theASM Publications Office, 1913 I St., N.W., Washington, DC20006 (area 202 833-9680).
at*: {^lRAt1M_ .XMX.-t 9 It
EX OFFICIOAlbert Balows, President-Elect (1979-1980)
Brinton M. Miller, Treasurer
Second-class postage paid at Washington, DC 20006, and atadditional mailing offices.Made in the U.S.A.Copyright i) 1980, American Society for Microbiology.All Rights Reserved.
The code at the top of the first page of an article in this journalindicates the copyright owner's consent that copies of the articlemay be made for personal use, or for personal use of specificclients. This consent is given on the condition, however, that thecopier pay the stated per-copy fee through the Copyright Clear-ance Center, Inc., P.O. Box 765, Schenectady, New York 12301,for copying beyond that permitted by Sections 107 and 108 ofthe U.S. Copyright Law. This consent does not extend to otherkinds of copying, such as copying for general distribution, foradvertising or promotional purposes, for creating new collectiveworks, or for resale.
Volume 34 Contents for April 1980 Number 1
A0nimal VirusesExtra RNAs of von Magnus Particles of Influenza Virus Cause
Reduction of Particular Polymerase Genes. M. UEDA,* K. NA-KAJIMA, AND A. SUGIURA .................................. 1-8
Characterization of Herpes Simplex Virus Type 1 RNA Present inthe Absence of De Novo Protein Synthesis. KEVIN P. ANDER-SON, ROBERT H. COSTA, LOUIS E. HOLLAND, AND EDWARD K.WAGNER* ............................................... 9-27
Baboon Endogenous Virus Genome. I. Restriction Enzyme Map ofthe Unintegrated DNA Genome of a Primate Retrovirus.MAURICE COHEN,* MARGERY 0. NICOLSON, ROBERT M. MC-ALLISTER, MAVIS SHURE, NORMAN DAVIDSON, NANCY RICE,AND RAYMOND V. GILDEN ...... ........................... 28-39
Temperature-Sensitive Mutants of Foot-and-Mouth Disease Viruswith Altered Structural Polypeptides. I. Identification by Elec-trofocusing. ANDREW M. Q. KING* AND JOHN W. I. NEWMAN 59-66
Temperature-Sensitive Mutants of Foot-and-Mouth Disease Viruswith Altered Structural Polypeptides. II. Comparison of Recom-bination and Biochemical Maps. ANDREW M. Q. KING,* WIL-LIAM R. SLADE, JOHN W. I. NEWMAN, AND DAVID MCCAHON 67-72
Comparative Biochemical Studies of Type 3 Poliovirus. PHILIP D.MINOR .................................................. 73-84
Short-Lived Minus-Strand Polymerase for Semliki Forest Virus.DOROTHEA L. SAWICKI* AND STANLEY G. SAWICKI ......... . 108-118
Separation of Neutralizing and Hemagglutination-Inhibiting Anti-body Activities and Specificity of Antisera to Sodium DodecylSulfate-Derived Polypeptides of Polyoma Virions. JOSEPH B.BOLEN AND RICHARD A. CONSIGLI* ........................ 119-129
In Vitro Cytotoxicity Against Marek's Disease Lymphoblastoid CellLines After Enzymatic Removal of Marek's Disease Tumor-Associated Surface Antigen. K. A. SCHAT* AND K. K. MURTHY 130-135
Effect of Tunicamycin on Herpes Simplex Virus Glycoproteins andInfectious Virus Production. LEWIS I. PIZER,* GARY H. COHEN,AND ROSELYN J. EISENBERG ...................... ......... 142-153
Glycopeptides of Murine Leukemia Viruses. II. Comparison of Xen-otropic and Dual-Tropic Viruses. MAURICE C. KEMP, NANCYG. FAMULARI, PAUL V. O'DONNELL, AND RICHARD W. COM-PANS ............ 154-161
Specific Antigenic Relationships Between the RNA-DependentDNAPolymerases of Avian Reticuloendotheliosis Viruses and Mam-malian Type C Retroviruses. GEORG BAUER AND HOWARD M.TEMIN* ................ 168-177
Viral DNA in BurSal Lymphomas Induced by Avian Leukosis Vi-ruses. PAUL NEIMAN,* L. N. PAYNE, AND ROBIN A. WEISs.. 178-186
Molecular Cloning of Snyder-Theilen Feline Leukemia and SarcomaViruses: Comparative Studies of Feline Sarcoma Virus with ItsNatural Helper Virus and with Moloney Murine Sarcoma Vi-rus. CHARLES J. SHERR,* LOUIS A. FEDELE, MARIANNE Os-KARSSON, JACOB MAIZEL, AND GEORGE VANDE WOUDE ...... 200-212
Association of a Murine 53,000-Dalton Phosphoprotein with SimianVirus 40 Large-T Antigen in Transformed Cells. FRANK MC-CORMICK* AND ED HARLOW...... ... 213-224
* Asterisk refers to person to whom inquiries regarding the paper should be addressed.
CONTENTS
Alterations of a Mouse Mammary Tumor Virus Glycoprotein withInterferon Treatment. MARY JANE YAGI,* NORVAL W. KING,JR., AND J. GEORGE BEKESI ............................... 225-233
Biochemical and Electron Microscopic Studies of the Replicationand Composition of Milker's Node Virus. V. THOMAS, L. FLO-RES, AND JOHN A. HOLOWCZAK* ............... ..... ... 244-255
Does the Major Histocompatibility Complex Serve as a SpecificReceptor for Semliki Forest Virus? MICHAEL B. A. OLD-STONE,* ANTOINETTE TISHON, FRANK J. DUTKO, S. IAN T.KENNEDY, JOHN J. HOLLAND, AND PETER W. LAMPERT 256-265
Polyamines in Encephalomyocarditis Virus. SARAH L. SHEPPARD,ALFRED T. H. BURNESS,* AND STEPHEN M. BOYLE .... 266-267
Protein Organization in Newcastle Disease Virus as Revealed byPerturbant Treatment. JOSEPH K.-K. LI, TOKiCHI MIYAKAWA,AND C. FRED Fox* ........................ ........ 268-271
Role of Two Particle Types in Bovine Rotavirus Morphogenesis.SCOTT M. CLARK,* REX S. SPENDLOVE, AND BILL B. BARNETT 272-276
Cell-Free Translation of Avian Erythroblastosis Virus RNA. TONYPAWSON* AND G. STEVEN MARTIN ................... 280-284
Genetic Variation During Lytic Reovirus Infection: High-PassageStocks of Wild-Type Reovirus Contain Temperature-SensitiveMutants. RAFI AHMED, P. R. CHAKRABORTY, AND B. N.FIELDS*.......... .......... 285-287
Inhibition of Virion-Associated Reverse Transcription by NucleosideTriphosphatase in Avian Myeloblastosis Virus. E. S. SRIVAT-SAN AND M. A. BALUDA* ...... ........... 288-292
Specificity of Protein Inhibitors in the Inhibition of Encephalomyo-carditis Virus Replication. TRIPRAYAR V. RAMABHADRAN ANDROBERT E. THACH* ................................... 293-296
Protein Kinase Activity in Hepatitis B Virus. CATHERINE ALBINAND WILLIAM S. ROBINSON* .. ...... 297-302
Bacterial VirusesNucleotide Sequences in Bacteriophage fl DNA: Nucleotide Se-
quence of Genes V, VII, and VIII. DIANA F. HILL AND GEORGEB. PETERSEN* ........................................... 40-50
Baseplate Protein of Bacteriophage T4 with Both Structural andLytic Functions. SHAO-HUI KAO AND WILLIAM H. MCCLAIN* 95-103
Roles of Bacteriophage T4 Gene 5 and Gene s Products in CellLysis. SHAO-HUI KAO AND WILLIAM H. MCCLAIN* ......... 104-107
Evidence for Direct Involvement of T7 RNA Polymerase in Bacte-riophage DNA Replication. DAVID C. HINKLE.... 136-141
Replication of Bacteriophage M13. XV. Location of the Specific Nickin M13 Replicative Form II Accumulated in Escherichia colipolAexl. NOBuo NOMURA AND DAN S. RAY*.... 162-167
Structure of Replicating DNA Molecules of Bacillus subtilis Bacte-riophage 429. MARTA R. INCIARTE, MARGARITA SALAS, ANDJOSE M. SOGO*... ... 187-199
Structure and Functions of the Bacteriophage P22 Tail Protein.PETER B. BERGET* AND ANTHONY R. POTEETE ............. 234-243
Specificity of the Bacteriophage Mu mom+-Controlled DNA Modi-fication. STANLEY HATTMAN .............................. 277-279
CONTENTS
Plant Viruses
Translation of Southern Bean Mosaic Virus RNA in Wheat Embryoand Rabbit Reticulocyte Extracts. TERRY SALERNO-RIFE,*TINEKE RUTGERS, AND PAUL KAESBERG ...... .............. 51-58
Post-Translational Proteolytic Cleavage of In Vitro-SynthesizedTurnip Yellow Mosaic Virus RNA-Coded High-Molecular-Weight Proteins. MARIE-DOMINIQUE MORCH* AND CLAUDEBENICOURT ............. 85-94
Errata
Biochemical and Immunological Characterization of PolyproteinsCoded for by the McDonough, Gardner-Arnstein, and Snyder-Theilen Strains of Feline Sarcoma Virus. MARIANO BARBACID,ANNE V. LAUVER, AND SUSHILKUMAR G. DEVARE ........... 303
In Vivo Methylation of Bacteriophage 4X174 DNA. STANLEYHATTMAN, CHRIS GRIBBIN, AND CLYDE A. HUTCHISON III .... 303
Volume 34 Contents for May 1980 Number 2
Animal VirusesPatterns of Viral DNA Integration in Cells Transformed by Wild
Type or DNA-Binding Protein Mutants of Adenovirus Type 5and Effect of Chemical Carcinogens on Integration. KAROLINEDORSCH-HASLER, PAUL B. FISHER, I. BERNARD WEINSTEIN,AND HAROLD S. GINSBERG* ........ ....................... 305-314
Simian Virus 40 T-Antigen: Identification of Tryptic Peptides in theC-TerminalRegionandDefinitionoftheReadingFrame. DAVIDT. DENHARDT* AND LIONEL V. CRAWFORD ..... ............. 315-329
Herpes Simplex Virus Glycoproteins: Isolation of Mutants Resistantto Immune Cytolysis. N. A. MACHTIGER, B. A. PANCAKE, R.EBERLE, R. J. COURTNEY, S. S. TEVETHIA, AND P. A.SCHAFFER* .............................................. 336-346
Characterization of Avian Myeloblastosis-Associated Virus DNAIntermediates. D. G. BERGMANN, L. M. SOUZA, AND M. A.BALUDA* ................................................ 366-372
Chromatin Conformation of Integrated Moloney Leukemia VirusDNA Sequences in Tissues of BALB/Mo Mice and in Virus-Infected Cell Lines. MICHAEL BREINDL,* LEE BACHELER,HUNG FAN, AND RUDOLPH JAENISCH ...... ................. 373-382
Genetic Variation During Persistent Reovirus Infection: Presence ofExtragenically Suppressed Temperature-Sensitive Lesions inWild-Type Virus Isolated from Persistently Infected LCells. RAFI AHMED, P. R. CHAKRABORTY, A. F. GRAHAM, R. F.RAMIG, AND B. N. FIELDS* ......... ....................... 383-389
Relationship of Retroviruses Isolated from Human Leukemia Tis-sues to the Woolly Monkey-Gibbon Ape Leukemia Vi-ruses. BARBARA G. SAHAGAN* AND WILLIAM A. HASELTINE 390-401
Nucleotide Sequence of the Inverted Terminal Repetition in Adeno-Associated Virus DNA. E. LUSBY, K. H. FIFE, AND K. I.BERNS* ............. ....... 402-409
CONTENTS
Genome of Porcine Transmissible Gastroenteritis Virus. DAVID A.BRIAN,* DOUGLAS E. DENNIS, AND JAMES S. GuY .... ....... 410-415
BK Virus DNA Sequence Coding for the t and T Antigens andEvaluation of Methods for Determining Sequence Homol-ogy. ROBERT C. A. YANG, ALEX YOUNG, AND RAY WU* ..... 416-430
Novel p19-Related Protein in Rous-Associated Virus Type 61: Im-plications for Avian gag Gene Order. DAVID J. SHEALY, ANNEG. MOSSER, AND ROLAND R. RUECKERT* ...... ............. 431-437
Interferon-Induced Proteins in Human Fibroblasts and Developmentof the Antiviral State. BERISH Y. RUBIN AND SOHAN L.GUPTA*........ 446-454
Polypeptide Synthesis and Phosphorylation in Epstein-Barr Virus-Infected Cells. ROBERT J. FEIGHNY,* MICHAEL P. FARRELL,AND JOSEPH S. PAGANO .......... ......................... 455-463
Suppression of Murine Retrovirus Polypeptide Termination: Effectof Amber Suppressor tRNA on the Cell-Free Translation ofRauscher Murine Leukemia Virus, Moloney Murine LeukemiaVirus, and Moloney Murine Sarcoma Virus 124 RNA. EDWINC. MURPHY, JR.,* NORMA WILLS, AND RALPH B. ARLINGHAUS 464-473
Biochemical Characterization of Equine Herpesvirus Type 3-InducedDeoxythymidine Kinase Purified from Lytically Infected HorseEmbryo Dermal Fibroblasts. JOHN J. MCGOWAN, GEORGE P.ALLEN, JOHN M. BARNETT, AND GLENN A. GENTRY* .. 474-483
Assembly of Avian Reticuloendotheliosis Virus: Association of theCore Precursor Polypeptide with the Intracellular Ribonucleo-protein Complex. TIMOTHY C. WONG, ROBERT B. LEWIS,HENRY R. BOSE, JR., AND C. YONG KANG* ..... ............. 484-489
mRNA Capping Enzymes Are Masked in Reovirus Progeny SubviralParticles. DANIAL SKUP AND STEWART MILLWARD* ........ 490-496
Reovirus Progeny Subviral Particles Synthesize UncappedmRNA. HELMUT ZARBL, DANIAL SKUP, AND STEWARTMILLWARD* ........................................... 497-505
Incomplete Influenza Virus: Partial Functional Complementation asRevealed by Hemadsorbing Cell Count Test. N. V. KAVERIN,*L. I. KOLOMIETZ, AND I. A. RUDNEVA ...... ................. 506-511
Immunoglobulin G(Fc)-Binding Receptors on Virions of Herpes Sim-plex Virus Type 1 and Transfer of These Receptors to the CellSurface by Infection. MICHAEL F. PARA, ROBERT B. BAUCKE,AND PATRICIA G. SPEAR* .......... ........................ 512-520
Structural Analysis of the Capsid Polypeptides of Herpes SimplexVirus Types 1 and 2. GARY H. COHEN,* MANUEL PONCE DELEON, HEIDI DIGGELMANN, WILLIAM C. LAWRENCE, STEVEN K.VERNON,AND ROSELYN J. EISENBERG ..... ................. 521-531
Site on the Vesicular Stomatitis Virus Genome Specifying Polyade-nylation and the End of the L Gene InRNA. MANFRED SCHU-BERT,* JACK D. KEENE, RONALD C. HERMAN, AND ROBERT A.LAZZARINI................................. 550-559
Effect ofAcyclovir [9-(2-Hydroxyethoxymethyl)guanine] on Epstein-Barr Virus DNA Replication. BRENDA M. COLBY,* JAMES E.SHAW, GERTRUDE B. ELION, AND JOSEPH S. PAGANO ........ 560-568
Modification of Avian Sarcoma Proviral DNA Sequences in Non-permissive XC Cells but Not in Permissive ChickenCells. RAMAREDDY V. GUNTAKA, * PRASAD Y. RAO, S. ALEXMITSIALIS, AND RICHARD KATZ ............................ 569-572
CONTENTS
Specificity of Initiation Factor Preparations from Poliovirus-InfectedCells. DONNA BROWN, JOANNA HANSEN, AND ELLIEEHRENFELD* ............................................ 573-575
Biochemical Characterization of Endogenous Type C Virus Infor-mation in Differentiated and Undifferentiated Murine Terato-carcinoma-Derived Cell Lines. RODICA EMANOIL-RAVICO-VITCH,* FRIDA HOJMAN-MONTES-DE-OCA, JACQUELINE ROB-ERT, MARYLENE GARCETFE, ROBERT CALLAHAN, JORGE PERIES,AND MICHEL BOIRON ............ ......................... 576-581
sizes Hydroxymethyldeoxyuridine Triphosphate. JAN NEU-HARD, K. L. MALTMAN, AND R. A. J. WARREN*.. 347-353
Synthesis of Thymnine and a-Putrescinylthymine in Bacteriophage4W-14-Infected Pseudomonas acidovorans. K. L. MALTMAN,*JAN NEUHARD, HILARY A. LEWIS, AND R. A. J. WARREN ..... 354-359
Rescue of Abortive T7 Gene 2 Mutant Phage Infection by Rif-ampin. MARTIN P. ONTELL AND DAI NAKADA* .... ......... 438-445
Physical Map of Caulobacter crescentus Bacteriophage 4CdlDNA. BILHA RABOY, LUCILLE SHAPIRO, * AND KEI AMEMIYA 542-549
Plant VirusesRegulation of Brome Mosaic Virus Gene Expression by Restriction
of Initiation of Protein Synthesis. JADWIGA CHROBOCZEK, *LUDMIWA PUCHKOVA, AND WYODZIMIERZ ZAGORSKI .... ...... 330-335
Expression of Wound Tumor Virus Gene Products In Vivo and InVitro. DONALD L. NUss* AND ANDREW J. PETERSON ....... 532-541
Insect VirusesComparison of the Structure of C- and N-Polyhedrins from Two
Occluded Viruses Pathogenic for Orgyia pseudotsugata. G. F.ROHRMANN, * T. J. BAILEY, R. R. BECKER, AND G. S.BEAUDREAU ... ........................... 360-365
ErratumMolecular Cloning of the Harvey Sarcoma Virus Circular DNA
Intermediates. II. Further Structural Analyses. HARDY W.CHAN, CLAUDE F. GARON, ESTHER H. CHANG, DOUGLAS R.LowY, GORDON L. HAGER, EDWARD M. SCOLNICK, Roy RE-PASKE, AND MALCOLM A. MARTIN .............. ..... 582
Volume 34 Contents for June 1980 Number 3Animal Viruses
Genetic Analysis of Orbiviruses by Using RNase T1 OligonucleotideFingerprints. PETER J. WALKER,* JONATHAN N. MANSBRIDGE,AND BARRY M. GORMAN .................................. 583-591
Expression of Early and Late Simian Virus 40 Transcripts in theAbsence of Protein Synthesis. HIROSHI HANDA AND PHILLIPA. SHARP*....................... 592-597
Defective Mutant of Sindbis Virus with a Smaller-Molecular-WeightForm of the El Glycoprotein. ARTURO LEONE, VITTORIO CO-LANTUONI, GIANFRANCO PONTARELLI, AND RANIERICANCEDDA* ............. ............... 598-603
CONTENTS
Gene Expression of Herpes Simplex Virus. II. UV Radiological Anal-ysis of Viral Transcription Units. ROBERT L. MILLETTE* ANDROSEMARIE KLAIBER ........... .......................... 604-614
Relationship Between Integrated and Nonintegrated Viral DNA inRat Cells Transformed by Polyoma Virus. SEBASTIANO GAT-TONI, VITTORIO COLANTUONI, AND CLAUDIO BASILICO* ....... 615-626
Heterogeneity of the Genome-Linked Protein of Foot-and-MouthDisease Virus. ANDREW M. Q. KING,* DAVID V. SANGAR,TIMOTHY J. R. HARRIS, AND FRED BROWN ..... ............. 627-634
Monoclonal Antibodies Identify Individual Determinants on MouseMammary Tumor Virus Glycoprotein gp52 with Group, Class,or Type Specificity. RICHARD J. MASSEY,* LARRY 0. ARTHUR,ROBERT C. NOWINSKI, AND GERALD SCHOCHETMAN .... ...... 635-643
Use of ['26I]Deoxycytidine to Detect Herpes Simplex Virus-SpecificThymidine Kinase in Tissues of Latently Infected GuineaPigs. BESSIE S. FONG AND MARIANNE SCRIBA* .... ........ 644-649
Relationship Among Tau Antigens Isolated from Various Lines ofSimian Virus 40-Transformed Cells. DANIEL T. SIMMONS,*MALCOLM A. MARTIN, PETER T. MORA, AND CHUNGMINGCHANG .................................................. 650-657
Adenovirus Regulation of Simian Virus 40 Macromolecular Synthe-sis. NEIL GOLDMAN* AND GEORGE KHOURY .... ........... 658-664
Cornovavirus Multiplication Strategy. I. Identification and Charac-terization of Virus-Specified RNA. DAVID F. STERN AND S.IAN T. KENNEDY*................... 665-674
Transcription of Reconstituted Simian Virus 40 Nucleoprotein Com-plexes. HIDEYUKI HIDAKA,* HIROMASA MISUMI, AND TAKUZOODA ..................................................... 675-683
Conserved Sequence Related to the 3'-Terminal Region ofRetrovirusRNAs in Normal Cellular DNAs. R. KOMINAMI, Y. TOMITA,E. C. CONNORS, AND M. HATANAKA* ....................... 684-692
Biochemical Transformation by Temperature-Sensitive Mutants ofHerpes Simplex Virus Type 1. FRED RAPP,* NANCY TURNER,AND PRISCILLA A. SCHAFFER .............................. 704-710
Late-Passage SC-1 Cells Resistant to N- and B-Tropic Viruses butSensitive to NB-Tropic Viruses. THEODORE PINCUS ........ 711-715
Recombination and Linkage Between Structural and RegulatoryGenes of Herpes Simplex Virus Type 1: Study of the FunctionalOrganization of the Genome. R. W. HONESS,* A. BUCHAN, I.W. HALLIBURTON, AND D. H. WATSON .................. ... 716-742
Avian Reticuloendotheliosis Virus: Characterization of the High-Molecular-Weight Viral RNA in Transforming and Helper VirusPopulations. MArTHEw A. GONDA,* NANCY R. RICE, ANDRAYMOND V. GILDEN .................. .... 743-751
Monoclonal Antibodies Against Simian Virus 40 T Antigens: Evi-dence for Distinct Subclasses of Large T Antigen and for Simi-larities Among Nonviral T Antigens. ELIZABETH G. GURNEY,*ROBERT O. HARRISON, AND JAMES FENNO.... 752-763
Electron Microscopy of Vesicular Stomatitis Virus Replicative Ri-bonucleoproteins. CLAYTON W. NAEVE* AND DONALD F.SUMMERS......... ... .. .. 764-771
Transformation of Rat Cells by Fusion-Infection with Rous SarcomaVirus. SADAAKI KAWAI..... 772-776
CONTENTS
Is Cytoskeleton Involved in Vesicular Stomatitis Virus Reproduc-tion? NIcoLE GENTY* AND FRAN,OISE BUSSEREAU ......... 777-781
Cytoplasmic T Antigens of Mouse and Human Cells Transformed bya Simian Virus 40 tsA Mutant. D. R. DUBBS,* H. OTSUKA, ANDS. KIT ................................................... 782-788
Proposal for a Uniform Nomenclature for Defective Interfering Vi-ruses of Vesicular Stomatitis Virus. M. E. REICHMANN, D. H.L. BISHOP, F. BROWN, J. CRICK, J. J. HOLLAND, C.-Y. KANG, R.LAZZARINI, S. MOYER, J. PERRAULT, L. PREVEC, C. R. PRINGLE,R. R. WAGNER, J. S. YOUNGNER, AND A. S. HUANG* ......... 792-794
RNA-Dependent DNA Polymerase of an Endogenous Type C Virusof Mice: Purification and Partial Characterization. AMNONHIZI* AND ABRAHAM YANIV ............................... 795-801
Bacterial VirusesExpression of Superinfection Immunity to Bacteriophage 4105 by
Bacillus subtilis Cells Carrying a Plasmid Chimera of pUBilOand EcoRI Fragment F of 4105 DNA. DORIS F. CULLY ANDANTHONY J. GARRO* .................................. 789-791
Insect VirusesPhysical Maps of Autographa californica and Rachiplusia ou Nu-
clear Polyhedrosis Virus Recombinants. MAX D. SUMMERS,*GALE E. SMITH, JOHN D. KNELL, AND JOHN P. BURAND ..... 693-703
ErratumState of Hepatitis B Viral DNA in a Human Hepatoma Cell
Line. PATRICIA L. MARION, FELIX H. SALAZAR, JENNIFER J.ALEXANDER, AND WILLIAM S. ROBINSON ...... ............. 802