JAHA: Journal of the American Heart Associationjaha.ahajournals.org/content/ahaoa/5/7.toc.pdf · Park, Hong Seog Seo, and Dong Joo Oh ... George S. Mendenhall, Jan Nemec, Samir Saba,

Editorials Screening for Atrial Fibrillation Using a Smartphone: Is There an App for That? Ben Freedman e004000 doi: 10.1161/JAHA.116.004000

Adults Are Not Just Enormous Children: Type 2 Diabetes Mellitus in Adults With Congenital Heart Disease Jason F. Deen and Eric V. Krieger e003960 doi: 10.1161/JAHA.116.003960

Patterns of Carotid Intima–Media Thickness Progression in Kawasaki Patients: A Crystal Ball for Long-Term Vascular Health? Jessica Haley and Elif Seda Selamet Tierney e003778 doi: 10.1161/JAHA.116.003778

Original Research Arrhythmia and Electrophysiology

Further Insights in the Most Common SCN 5A Mutation Causing Overlapping Phenotype of Long QT Syndrome, Brugada Syndrome, and Conduction Defect Christian Veltmann, Hector Barajas-Martinez, Christian Wolpert, Martin Borggrefe, Rainer Schimpf, Ryan Pfeiffer, Gabriel Cáceres, Elena Burashnikov, Charles Antzelevitch, and Dan Hu e003779 doi: 10.1161/JAHA.116.003779

Temporary Suppression of Cardiac Ganglionated Plexi Leads to Long-Term Suppression of Atrial Fibrillation: Evidence of Early Autonomic Intervention to Break the Vicious Cycle of “AF Begets AF” Li-Wei Lo, Hung-Yu Chang, Benjamin J. Scherlag, Yenn-Jiang Lin, Yu-Hui Chou, Wei-Lun Lin, Shih-Ann Chen, and Sunny S. Po e003309 doi: 10.1161/JAHA.116.003309

Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF-TIMI 48 Trial Alon Eisen, Christian T. Ruff, Eugene Braunwald, Francesco Nordio, Ramón Corbalán, Anthony Dalby, Maria Dorobantu, Michele Mercuri, Hans Lanz, Howard Rutman, Stephen D. Wiviott, Elliott M. Antman, and Robert P. Giugliano e003735 doi: 10.1161/JAHA.116.003735

Catheter Ablation as a Treatment for Vasovagal Syncope: Long-Term Outcome of Endocardial Autonomic Modification of the Left Atrium Wei Sun, Lihui Zheng, Yu Qiao, Rui Shi, Bingbo Hou, Lingmin Wu, Jinrui Guo, Shu Zhang, and Yan Yao e003471 doi: 10.1161/JAHA.116.003471

Advanced Left Atrial Remodeling and Appendage Contractile Dysfunction in Women Than in Men Among the Patients With Atrial Fibrillation: Potential Mechanism for Stroke Hee Tae Yu, Jihei Sara Lee, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Geu-Ru Hong, Moon-Hyoung Lee, Chi Young Shim, and Hui-Nam Pak e003361 doi: 10.1161/JAHA.116.003361

Diagnostic Performance of a Smartphone-Based Photoplethysmographic Application for Atrial Fibrillation Screening in a Primary Care Setting Pak-Hei Chan, Chun-Ka Wong, Yukkee C. Poh, Louise Pun, Wangie Wan-Chiu Leung, Yu-Fai Wong, Michelle Man-Ying Wong, Ming-Zher Poh, Daniel Wai-Sing Chu, and Chung-Wah Siu e003428 doi: 10.1161/JAHA.116.003428

JAHA: Journal of the American Heart AssociationVolume 5, Issue 7

July 2016

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Impact of Renin-Angiotensin System Inhibitors on Long-Term Clinical Outcomes of Patients With Coronary Artery Spasm Byoung Geol Choi, Sung Yeon Jeon, Seung-Woon Rha, Sang-Ho Park, Min Suk Shim, Se Yeon Choi, Jae Kyeong Byun, Hu Li, Jah Yeon Choi, Eun Jin Park, Sung-Hun Park, Jae Joong Lee, Sunki Lee, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, and Dong Joo Oh e003217 doi: 10.1161/JAHA.116.003217

Long-Term Impact of Right Ventricular Pacing on Left Ventricular Systolic Function in Pacemaker Recipients With Preserved Ejection Fraction: Results From a Large Single-Center Registry Micaela Ebert, Nikolaus Jander, Jan Minners, Thomas Blum, Michael Doering, Andreas Bollmann, Gerhard Hindricks, Thomas Arentz, Dietrich Kalusche, and Sergio Richter e003485 doi: 10.1161/JAHA.116.003485

Incidence and Predictors of Complications During Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation Emily N. Guhl, Donald Siddoway, Evan Adelstein, Raveen Bazaz, George S. Mendenhall, Jan Nemec, Samir Saba, David Schwartzman, Andrew Voigt, Norman C. Wang, and Sandeep K. Jain e003724 doi: 10.1161/JAHA.116.003724

Cardiovascular Surgery Design and Rationale of the Best Endovascular Versus Best Surgical Therapy for Patients With Critical Limb Ischemia (BEST-CLI) Trial Matthew T. Menard, Alik Farber, Susan F. Assmann, Niteesh K. Choudhry, Michael S. Conte, Mark A. Creager, Michael D. Dake, Michael R. Jaff, John A. Kaufman, Richard J. Powell, Diane M. Reid, Flora Sandra Siami, George Sopko, Christopher J. White, and Kenneth Rosenfield e003219 doi: 10.1161/JAHA.116.003219

Atrial Fibrillation Patients Treated With Long-Term Warfarin Anticoagulation Have Higher Rates of All Dementia Types Compared With Patients Receiving Long-Term Warfarin for Other Indications T. Jared Bunch, Heidi T. May, Tami L. Bair, Brian G. Crandall, Michael J. Cutler, John D. Day, Victoria Jacobs, Charles Mallender, Jeffrey S. Osborn, Scott M. Stevens, J. Peter Weiss, and Scott C. Woller e003932 doi: 10.1161/JAHA.116.003932

Glycogen Synthase Kinase 3β Inhibition Improves Myocardial Angiogenesis and Perfusion in a Swine Model of Metabolic Syndrome Brittany A. Potz, Ashraf A. Sabe, Nassrene Y. Elmadhun, Richard T. Clements, Michael P. Robich, Neel R. Sodha, and Frank W. Sellke e003694 doi: 10.1161/JAHA.116.003694

Development of a Telemetric System for Postoperative Follow-up of Vascular Surgery Procedures: In Vitro Model Manuel Hernando Rydings, Pilar Marín Palacios, Ana M. Aragón-Sánchez, Esther Bravo Ruiz, Victor Lopez-Dominguez, Isaac Martínez López, Cristina Fernández Pérez, Amaia Bilbao González, Francisco Javier Serrano Hernando, Reyes Vega Manrique, and Antonio Hernando Grande e003608 doi: 10.1161/JAHA.116.003608

Impact of South Asian Ethnicity on Long-Term Outcomes After Coronary Artery Bypass Grafting Surgery: A Large Population-Based Propensity Matched Study Saswata Deb, Jack V. Tu, Peter C. Austin, Dennis T. Ko, Rodolfo Rocha, C. David Mazer, Alex Kiss, and Stephen E. Fremes e003941 doi: 10.1161/JAHA.116.003941

Congenital Heart Disease Congenital Heart Disease With and Without Cyanotic Potential and the Long-term Risk of Diabetes Mellitus: A Population-Based Follow-up Study Nicolas L. Madsen, Bradley S. Marino, Jessica G. Woo, Reimar W. Thomsen, Jørgen Videbœk, Henning Bœkgaard Laursen, and Morten Olsen e003076 doi: 10.1161/JAHA.115.003076

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Impact of Surgical Complexity on Health-Related Quality of Life in Congenital Heart Disease Surgical Survivors Amy M. O’Connor, Jo Wray, Ryan S. Tomlinson, Amy Cassedy, Jeffrey P. Jacobs, Kathy J. Jenkins, Kate L. Brown, Rodney C. G. Franklin, Lynn Mahony, Kathleen Mussatto, Jane W. Newburger, Gil Wernovsky, Richard F. Ittenbach, Dennis Drotar, and Bradley S. Marino e001234 doi: 10.1161/JAHA.114.001234

Coronary Heart Disease Plasma Macrophage Migration Inhibitor Factor Is Elevated in Response to Myocardial Ischemia Fenling Fan, Lu Fang, Xiao-Lei Moore, Xuegang Xie, Xiao-Jun Du, David A. White, Jessica O’Brien, Helen Thomson, Jun Wang, Hans G. Schneider, Andris Ellims, Thomas W. Barber, and Anthony M. Dart e003128 doi: 10.1161/JAHA.115.003128

Automated Extracellular Volume Fraction Mapping Provides Insights Into the Pathophysiology of Left Ventricular Remodeling Post–Reperfused ST-Elevation Myocardial Infarction Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Steven K. White, Anish N. Bhuva, Thomas A. Treibel, Marianna Fontana, Esther Gonzalez-Lopez, Patricia Reant, Manish Ramlall, Ashraf Hamarneh, Alex Sirker, Anna S. Herrey, Charlotte Manisty, Derek M. Yellon, Peter Kellman, James C. Moon, and Derek J. Hausenloy e003555 doi: 10.1161/JAHA.116.003555

Time Dependence of the Effect of Right Ventricular Dysfunction on Clinical Outcomes After Myocardial Infarction: Role of Pulmonary Hypertension Keren Shahar, Wisam Darawsha, Sergey Yalonetsky, Jonathan Lessick, Michael Kapeliovich, Robert Dragu, Diab Mutlak, Shimon Reisner, Yoram Agmon, and Doron Aronson e003606 doi: 10.1161/JAHA.116.003606

Universal Classification System Type of Incident Myocardial Infarction in Patients With Stable Atherosclerosis: Observations From Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)-TIMI 50 Stephen K. Kidd, Marc P. Bonaca, Eugene Braunwald, Gaetano M. De Ferrari, Basil S. Lewis, Piera A. Merlini, Sabina A. Murphy, Benjamin M. Scirica, Harvey D. White, and David A. Morrow e003237 doi: 10.1161/JAHA.116.003237

Nanoparticle-Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia-Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction Ayako Ishikita, Tetsuya Matoba, Gentaro Ikeda, Jun-Ichiro Koga, Yajing Mao, Kaku Nakano, Osamu Takeuchi, Junichi Sadoshima, and Kensuke Egashira e003872 doi: 10.1161/JAHA.116.003872

Epidemiology Lifetime Risk for Sudden Cardiac Death in the Community Brittany M. Bogle, Hongyan Ning, Sanjay Mehrotra, Jeffrey J. Goldberger, and Donald M. Lloyd-Jones e002398 doi: 10.1161/JAHA.115.002398

Twenty-Five Year Secular Trends in Lipids and Modifiable Risk Factors in a Population-Based Biracial Cohort: The Coronary Artery Risk Development in Young Adults (CARDIA) Study, 1985–2011 Pamela J. Schreiner, David R. Jacobs Jr, Nathan D. Wong, and Catarina I. Kiefe e003384 doi: 10.1161/JAHA.116.003384

Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association With Cardiovascular Disease and Mortality in the Framingham Heart Study Robin Haring, Danielle Enserro, Vanessa Xanthakis, Gary F. Mitchell, Emelia J. Benjamin, Naomi M. Hamburg, Lisa Sullivan, Matthias Nauck, Henri Wallaschofski, and Ramachandran S. Vasan e003486 doi: 10.1161/JAHA.116.003486

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Trends in Cardiovascular Health Metrics in Obese Adults: National Health and Nutrition Examination Survey (NHANES), 1988–2014 Fangjian Guo and W. Timothy Garvey

e003619 doi: 10.1161/JAHA.116.003619

Stability of High-Quality Warfarin Anticoagulation in a Community-Based Atrial Fibrillation Cohort: The Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study Liane O. Dallalzadeh, Alan S. Go, Yuchiao Chang, Leila H. Borowsky, Margaret C. Fang, and Daniel E. Singer

e003482 doi: 10.1161/JAHA.116.003482

Sex-Specific Association of Obstructive Sleep Apnea With Retinal Microvascular Signs: The Multi-Ethnic Study of Atherosclerosis Gen-Min Lin, Susan Redline, Ronald Klein, Laura A. Colangelo, Mary Frances Cotch, Tien Y. Wong, Barbara E. K. Klein, Sanjay R. Patel, Steven J. Shea, and Kiang Liu e003598 doi: 10.1161/JAHA.116.003598

Genetics Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms Femke N. G. van ’t Hof, Ynte M. Ruigrok, Cue Hyunkyu Lee, Stephan Ripke, Graig Anderson, Mariza de Andrade, Annette F. Baas, Jan D. Blankensteijn, Erwin P. Böttinger, Matthew J. Bown, Joseph Broderick, Philippe Bijlenga, David S. Carrell, Dana C. Crawford, David R. Crosslin, Christian Ebeling, Johan G. Eriksson, Myriam Fornage, Tatiana Foroud, Mikael von und zu Fraunberg, Christoph M. Friedrich, Emília I. Gaál, Omri Gottesman, Dong-Chuan Guo, Seamus C. Harrison, Juha Hernesniemi, Albert Hofman, Ituro Inoue, Juha E. Jääskeläinen, Gregory T. Jones, Lambertus A. L. M. Kiemeney, Riku Kivisaari, Nerissa Ko, Seppo Koskinen, Michiaki Kubo, Iftikhar J. Kullo, Helena Kuivaniemi, Mitja I. Kurki, Aki Laakso, Dongbing Lai, Suzanne M. Leal, Hanna Lehto, Scott A. LeMaire, Siew-Kee Low, Jennifer Malinowski, Catherine A. McCarty, Dianna M. Milewicz, Thomas H. Mosley, Yusuke Nakamura, Hirofumi Nakaoka, Mika Niemelä, Jennifer Pacheco, Peggy L. Peissig, Joanna Pera, Laura Rasmussen-Torvik, Marylyn D. Ritchie, Fernando Rivadeneira, Andre M. van Rij, Regie Lyn P. Santos-Cortez, Athanasios Saratzis, Agnieszka Slowik, Atsushi Takahashi, Gerard Tromp, André G. Uitterlinden, Shefali S. Verma, Sita H. Vermeulen, Gao T. Wang, Aneurysm Consortium, Vascular Research Consortium of New Zealand, Buhm Han, Gabriel J. E. Rinkel, and Paul I. W. de Bakker

e002603 doi: 10.1161/JAHA.115.002603

Health Services and Outcomes Research Providing Cardiology Care in Rural Areas Through Visiting Consultant Clinics Thomas S. Gruca, Tae-Hyung Pyo, and Gregory C. Nelson

e002909 doi: 10.1161/JAHA.115.002909

Systematic Review of Low-Density Lipoprotein Cholesterol Apheresis for the Treatment of Familial Hypercholesterolemia Anthony Wang, Akshara Richhariya, Shravanthi R. Gandra, Brian Calimlim, Lisa Kim, Ruben G. W. Quek, Robert J. Nordyke, and Peter P. Toth e003294 doi: 10.1161/JAHA.116.003294

Association Between Hospital Performance on Patient Safety and 30-Day Mortality and Unplanned Readmission for Medicare Fee-for-Service Patients With Acute Myocardial Infarction Yun Wang, Noel Eldridge, Mark L. Metersky, Nancy Sonnenfeld, Jonathan M. Fine, Michelle M. Pandolfi, Sheila Eckenrode, Anila Bakullari, Deron H. Galusha, Lisa Jaser, Nancy R. Verzier, Sudhakar V. Nuti, David Hunt, Sharon-Lise T. Normand, and Harlan M. Krumholz

e003731 doi: 10.1161/JAHA.116.003731

Kidney Function Does Not Modify the Favorable Quality of Life Changes Associated With Revascularization for Coronary Artery Disease: Cohort Study Matthew T. James, Stephen B. Wilton, Fiona M. Clement, William A. Ghali, Merril L. Knudtson, Zhi Tan, Marcello Tonelli, Brenda R. Hemmelgarn, Colleen M. Norris, and for the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) and Alberta Kidney Disease Network (AKDN) Investigators e003642 doi: 10.1161/JAHA.116.003642

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Care Setting Intensity and Outcomes After Emergency Department Presentation Among Patients With Acute Heart Failure Livia Goldraich, Peter C. Austin, Limei Zhou, Jack V. Tu, Michael J. Schull, Susanna Mak, Heather J. Ross, David A. Morrow, and Douglas S. Lee e003232 doi: 10.1161/JAHA.116.003232

Heart Failure Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability Erminia Donnarumma, Murtuza J. Ali, Amanda M. Rushing, Amy L. Scarborough, Jessica M. Bradley, Chelsea L. Organ, Kazi N. Islam, David J. Polhemus, Stefano Evangelista, Giuseppe Cirino, J. Stephen Jenkins, Rajan A. G. Patel, David J. Lefer, and Traci T. Goodchild e003531 doi: 10.1161/JAHA.116.003531

Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-α (HIF1-α) in an Ovine Model of Acute Myocardial Infarction Anna P. Hnatiuk, Sang-Ging Ong, Fernanda D. Olea, Paola Locatelli, Johannes Riegler, Won Hee Lee, Cheng Hao Jen, Andrea De Lorenzi, Carlos S. Giménez, Rubén Laguens, Joseph C. Wu, and Alberto Crottogini e003714 doi: 10.1161/JAHA.116.003714

Hypertension Transglutaminase is a Critical Link Between Inflammation and Hypertension Renna Luo, Chen Liu, Serra E. Elliott, Wei Wang, Nicholas Parchim, Takayuki Iriyama, Patrick S. Daugherty, Lijian Tao, Holger K. Eltzschig, Sean C. Blackwell, Baha M. Sibai, Rodney E. Kellems, and Yang Xia e003730 doi: 10.1161/JAHA.116.003730

Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Maria-Corina Serban, Amirhossein Sahebkar, Alberto Zanchetti, Dimitri P. Mikhailidis, George Howard, Diana Antal, Florina Andrica, Ali Ahmed, Wilbert S. Aronow, Paul Muntner, Gregory Y. H. Lip, Ian Graham, Nathan Wong, Jacek Rysz, Maciej Banach, and for the Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group e002713 doi: 10.1161/JAHA.115.002713

Prevalence of Eligibility Criteria for the Systolic Blood Pressure Intervention Trial in US Adults Among Excluded Groups: Age <50 Years, Diabetes Mellitus, or a History of Stroke Adam P. Bress, Rikki M. Tanner, Rachel Hess, Samuel S. Gidding, Lisandro D. Colantonio, Daichi Shimbo, and Paul Muntner e003547 doi: 10.1161/JAHA.116.003547

Genetic Abrogation of Adenosine A 3 Receptor Prevents Uninephrectomy and High Salt–Induced Hypertension Ting Yang, Christa Zollbrecht, Malin E. Winerdal, Zhengbing Zhuge, Xing-Mei Zhang, Niccolo Terrando, Antonio Checa, Johan Sällström, Craig E. Wheelock, Ola Winqvist, Robert A. Harris, Erik Larsson, A. Erik G. Persson, Bertil B. Fredholm, and Mattias Carlström e003868 doi: 10.1161/JAHA.116.003868

Endothelin-1 Drives Epithelial-Mesenchymal Transition in Hypertensive Nephroangiosclerosis Teresa M. Seccia, Brasilina Caroccia, Francesca Gioco, Maria Piazza, Valentina Buccella, Diego Guidolin, Eugenia Guerzoni, Barbara Montini, Lucia Petrelli, Elisa Pagnin, Verdiana Ravarotto, Anna S. Belloni, Lorenzo A. Calò, and Gian Paolo Rossi e003888 doi: 10.1161/JAHA.116.003888

Imaging Comprehensive Cardiac Magnetic Resonance for Short-Term Follow-Up in Acute Myocarditis Julian A. Luetkens, Rami Homsi, Darius Dabir, Daniel L. Kuetting, Christian Marx, Jonas Doerner, Ulrike Schlesinger-Irsch, René Andrié, Alois M. Sprinkart, Frederic C. Schmeel, Christian Stehning, Rolf Fimmers, Juergen Gieseke, Claas P. Naehle, Hans H. Schild, and Daniel K. Thomas e003603 doi: 10.1161/JAHA.116.003603

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Interventional Cardiology Effect of Varying Hemodynamic and Vascular Conditions on Fractional Flow Reserve: An In Vitro Study Kranthi K. Kolli, James K. Min, Seongmin Ha, Hilary Soohoo, and Guanglei Xiong e003634 doi: 10.1161/JAHA.116.003634

Prolonged High-Dose Bivalirudin Infusion Reduces Major Bleeding Without Increasing Stent Thrombosis in Patients Undergoing Primary Percutaneous Coronary Intervention: Novel Insights From an Updated Meta-Analysis Gregor Fahrni, Mathias Wolfrum, Giovanni Luigi De Maria, Adrian P. Banning, Umberto Benedetto, and Rajesh K. Kharbanda e003515 doi: 10.1161/JAHA.116.003515

Kidney in Cardiovascular Disease Acute Kidney Injury Definition and In-Hospital Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Giancarlo Marenzi, Nicola Cosentino, Marco Moltrasio, Mara Rubino, Gabriele Crimi, Stefano Buratti, Marco Grazi, Valentina Milazzo, Alberto Somaschini, Rita Camporotondo, Stefano Cornara, Monica De Metrio, Alice Bonomi, Fabrizio Veglia, Gaetano M. De Ferrari, and Antonio L. Bartorelli e003522 doi: 10.1161/JAHA.116.003522

Vascular Function at Baseline in the Hemodialysis Fistula Maturation Study Laura M. Dember, Peter B. Imrey, Mai-Ann Duess, Naomi M. Hamburg, Brett Larive, Milena Radeva, Jonathan Himmelfarb, Larry W. Kraiss, John W. Kusek, Prabir Roy-Chaudhury, Christi M. Terry, Miguel A. Vazquez, Wanpen Vongpatanasin, Gerald J. Beck, Joseph A. Vita, and Hemodialysis Fistula Maturation Study Group e003227 doi: 10.1161/JAHA.116.003227

Reduced Kidney Function Is Associated With Cardiometabolic Risk Factors, Prevalent and Predicted Risk of Cardiovascular Disease in Chinese Adults: Results From the REACTION Study Jieli Lu, Yiming Mu, Qing Su, Lixin Shi, Chao Liu, Jiajun Zhao, Lulu Chen, Qiang Li, Tao Yang, Li Yan, Qin Wan, Shengli Wu, Yan Liu, Guixia Wang, Zuojie Luo, Xulei Tang, Gang Chen, Yanan Huo, Zhengnan Gao, Zhen Ye, Youmin Wang, Guijun Qin, Huacong Deng, Xuefeng Yu, Feixia Shen, Li Chen, Liebin Zhao, Jichao Sun, Wanwan Sun, Tiange Wang, Rui Du, Lin Lin, Meng Dai, Yu Xu, Min Xu, Yufang Bi, Shenghan Lai, Donghui Li, Weiqing Wang, Guang Ning, and on behalf of the REACTION Study Group e003328 doi: 10.1161/JAHA.116.003328

Molecular Cardiology Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy Shin Ito, Masanori Asakura, Yulin Liao, Kyung-Duk Min, Ayako Takahashi, Kazuhiro Shindo, Satoru Yamazaki, Osamu Tsukamoto, Hiroshi Asanuma, Masaki Mogi, Masatsugu Horiuchi, Yoshihiro Asano, Shoji Sanada, Tetsuo Minamino, Seiji Takashima, Naoki Mochizuki, and Masafumi Kitakaze e003521 doi: 10.1161/JAHA.116.003521

Pigment Epithelium-Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF-R) Peng Lu, Yi-Qian Zhang, Hao Zhang, Yu-Feng Li, Xiao-Yu Wang, Hao Xu, Zhi-Wei Liu, Lei Li, Hong-Yan Dong, and Zhong-Ming Zhang e003179 doi: 10.1161/JAHA.115.003179

Pediatric Cardiology Natural History of Dilated Cardiomyopathy in Children Ilaria Puggia, Marco Merlo, Giulia Barbati, Teisha J. Rowland, Davide Stolfo, Marta Gigli, Federica Ramani, Andrea Di Lenarda, Luisa Mestroni, and Gianfranco Sinagra e003450 doi: 10.1161/JAHA.116.003450

Extracardial Vasculopathy After Kawasaki Disease: A Long-Term Follow-up Study Sanne M. Dietz, Carline E. Tacke, Eric de Groot, Irene M. Kuipers, Barbara A. Hutten, Taco W. Kuijpers, and Dutch Kawasaki Study Group e003414 doi: 10.1161/JAHA.116.003414

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Preventive Cardiology Circulating N-Linked Glycoprotein Side-Chain Biomarker, Rosuvastatin Therapy, and Incident Cardiovascular Disease: An Analysis From the JUPITER Trial Akintunde O. Akinkuolie, Robert J. Glynn, Latha Padmanabhan, Paul M Ridker, and Samia Mora e003822 doi: 10.1161/JAHA.116.003822

Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial Günther Silbernagel, David Spirk, Adrian Hager, Iris Baumgartner, and Nils Kucher e003776 doi: 10.1161/JAHA.116.003776

Resuscitation Science Glibenclamide Is Comparable to Target Temperature Management in Improving Survival and Neurological Outcome After Asphyxial Cardiac Arrest in Rats Kaibin Huang, Ziyue Wang, Yong Gu, Yafang Hu, Zhong Ji, Shengnan Wang, Zhenzhou Lin, Xing Li, Zuoshan Xie, and Suyue Pan e003465 doi: 10.1161/JAHA.116.003465

Stroke Ischemic Stroke Risk After Acute Coronary Syndrome Shadi Yaghi, Markeith Pilot, Christopher Song, Christina A. Blum, Aleksandra Yakhkind, Brian Silver, Karen L. Furie, Mitchell S. V. Elkind, Dean Sherzai, and Ayesha Z. Sherzai e002590 doi: 10.1161/JAHA.115.002590

Particulate Matter and Hospital Admissions for Stroke in Beijing, China: Modification Effects by Ambient Temperature Fangfang Huang, Yanxia Luo, Yuming Guo, Lixin Tao, Qin Xu, Chao Wang, Anxin Wang, Xia Li, Jin Guo, Aoshuang Yan, and Xiuhua Guo e003437 doi: 10.1161/JAHA.116.003437

Valvular Heart Disease Prevalence, Predictors and Clinical Outcome of Residual Pulmonary Hypertension Following Tricuspid Annuloplasty Yan Chen, Ju-Hua Liu, Daniel Chan, Ko-Yung Sit, Chun-Ka Wong, Kar-Lai Ho, Lai-Ming Ho, Zhe Zhen, Yui-Ming Lam, Chu-Pak Lau, Wing-Kok Au, Hung-Fat Tse, and Kai-Hang Yiu e003353 doi: 10.1161/JAHA.116.003353

Vascular Medicine Obesity Is Associated With Progression of Atherosclerosis During Statin Treatment Veit Sandfort, Shenghan Lai, Mark A. Ahlman, Marissa Mallek, Songtao Liu, Christopher T. Sibley, Evrim B. Turkbey, João A. C. Lima, and David A. Bluemke e003621 doi: 10.1161/JAHA.116.003621

Special Report Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop Amrita Ahluwalia, Mark Gladwin, Gary D. Coleman, Norman Hord, George Howard, Daniel B. Kim-Shapiro, Martin Lajous, Filip J. Larsen, David J. Lefer, Leslie A. McClure, Bernard T. Nolan, Ryszard Pluta, Alan Schechter, Chia-Yih Wang, Mary H. Ward, and Jane L. Harman e003402 doi: 10.1161/JAHA.116.003402

Contemporary Reviews G Protein–Coupled Receptor Kinases: Crucial Regulators of Blood Pressure Jian Yang, Van Anthony M. Villar, Ines Armando, Pedro A. Jose, and Chunyu Zeng e003519 doi: 10.1161/JAHA.116.003519

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Defining a Mobile Health Roadmap for Cardiovascular Health and Disease Zubin J. Eapen, Mintu P. Turakhia, Michael V. McConnell, Garth Graham, Patrick Dunn, Colby Tiner, Carlo Rich, Robert A. Harrington, Eric D. Peterson, and Patrick Wayte e003119 doi: 10.1161/JAHA.115.003119

Council News and Views Noncoding Genome-Wide Association Studies Variant for Obesity: Inroads Into Mechanism : An Overview From the AHA’s Council on Functional Genomics and Translational Biology Connie Wu and Pankaj Arora e003060 doi: 10.1161/JAHA.115.003060

Corrections False Lumen Status in Patients With Acute Aortic Dissection: A Systematic Review and Meta-Analysis e002068 doi: 10.1161/JAHA.116.002068

Racial Differences in Electrocardiographic Characteristics and Prognostic Significance in Whites Versus Asians e002058 doi: 10.1161/JAHA.116.002058

Circulating Brain-Derived Neurotrophic Factor Concentrations and the Risk of Cardiovascular Disease in the Community e002098 doi: 10.1161/JAHA.116.002098

Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study e002100 doi: 10.1161/JAHA.116.002100

Plasma Levels of Proprotein Convertase Subtilisin/Kexin Type 9 Are Elevated in Patients With Peripheral Artery Disease and Associated With Metabolic Disorders and Dysfunction in Circulating Progenitor Cells e002090 doi: 10.1161/JAHA.116.002090

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Online ISSN: 2047-9980 Dallas, TX 75231

is published by the American Heart Association, 7272 Greenville Avenue,Journal of the American Heart AssociationThe 2016;5:; originally published July 1, 2016;J Am Heart Assoc. 

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