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Introduction to Pain and Anxiety Control

Mar 01, 2018

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    Kyle J. Kramer, DDS, MS

    7/12/11

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    ! Inhalation Minimal Sedation! 14 hours of instruction

    ! Clinical competency

    !

    Enteral and/or Combination Inhalation-EnteralMinimal Sedation! Current BLS

    ! 16 hours of instruction

    ! Clinical competency

    !

    Experience compromised airway management

    Note: Guidelines do not pertain to sedation of pediatricpatients

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    !

    Moderate Enteral Sedation! 24 hours of instruction

    ! 10 adult patient case experiences*

    "

    Enteral" Enteral-Nitrous Oxide

    ! Clinical competency

    ! Management of compromised airway

    Note: Guidelines do not pertain to sedation ofpediatric patients

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    !

    Moderate Parenteral (IV) Sedation

    ! 60 hours of instruction

    ! 20 adult patient case experiences

    !

    Clinical competency

    ! Management of compromised airway

    Note: Guidelines do not pertain to sedation ofpediatric patients

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    ! Successful completion fulfills didactic requirements! 14 hours ACLS

    ! 10 classes over next 5 weeks" Lectures

    "

    Midterm"

    8/1 to 8/8

    " Final exam"

    8/15 to 8/22

    " Labs"

    IV placement/IM injections"

    Preoperative evaluation and ASA Monitors

    !

    2 sessions"

    Airway Lab (2 half-days w/ Dr. Kramer in OMS clinic)

    ! Competency Evaluation" Case review and presentation/oral evaluation

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    !

    Define and describe pain, anxiety and fear

    !

    Review historical, philosophical andpsychological aspects of anxiety and pain

    control!

    Define consciousness and levels ofsedation! Minimal sedation

    !

    Moderate sedation

    ! Deep sedation

    ! General anesthesia

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    ! 40% of population doesnt receive routinedental care! Apprehension given for most common reason

    ! Mild apprehension of dental treatment! Very common: 75% of population

    !

    Severe anxiety leading to avoidance oftreatment! Less common: 6-20% of population

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    ! In the US an estimated6-14% of thepopulation avoidsdental care due to fear

    of dentistry! 14-34 million

    ! Anxiety and fearremain significant

    roadblocks to patientcare! Despite advances in pain

    control

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    n = 400

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    Problems

    1. Poor oral health

    2.

    Patients are fearful of dentaltreatment

    3.

    Inadequate access to care1. Few dental sedationists

    compared to number of patients2. Remains a problem despite

    improvements

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    Fear continues to besignificant barrier to

    patient care! Public Speaking 27%! Dentists 21%! Heights 20%

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    Our Goals

    ! Improve access to care!

    Improve patient care andcomfort

    !

    Our professional obligation todo better

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    Methods of improving access tocare

    !

    Non-pharmacologic! Verbal guidance and reassurance! Distraction (listen to music, watch a

    movie)!

    Hypnosis

    !

    Pharmacologic! Anxiolysis! Minimal sedation! Moderate sedation! Deep sedation! General anesthesia

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    !

    An unpleasant sensory and emotionalexperience associated with actual or

    potential tissue damage, or described in

    terms of such damage InternationalAssociation for the Study of Pain

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    !

    Neural processes of encoding andprocessing noxious stimuli

    ! Afferent activity blocked by local anesthetics

    !

    Autonomic process

    ! Consciousness not required

    !

    Intraoperative and postoperative

    importance! An absolute must for all types of sedation

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    !

    Activation of the sympathetic nervoussystem

    ! Release of epinephrine from adrenal glands

    !

    Fight or flight response

    ! Emotional responses

    " Crying, scared, etc.

    !

    Physical responses" Tachycardia, hyperventilation

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    ! Short-livedphenomenon,disappearingwhen theexternal danger orthreat passes

    ! Autonomic responsedependentof thethreat! If the threat (a spider) is

    present

    activation of thefear response

    ! Once spider is gone, thefear response resolves

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    1.

    Fear of pain*

    Is it going to hurt?

    2.

    Fear of the unknown

    3.

    Fear of helplessness and dependency

    4. Fear of bodily change and mutilation

    5.

    Fear of death

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    ! Arise from many

    sources

    ! Past traumatic

    experiences! Observation of others

    ! Concerns or worries

    ! Exposure to anecdotal

    stories

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    1.

    Fear of pain*

    Is it going to hurt?

    2.

    Fear of the unknown

    3.

    Fear of helplessness and dependency

    4. Fear of bodily change and mutilation

    5.

    Fear of death

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    !

    Both groups had

    similar fears

    !

    Dentists can

    eliminate sometriggers

    ! What do patients

    care about?

    ! No pain!

    ! Work quality???

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    ! A specific unpleasurable state oftension which indicates thepresence of some danger to theorganism Weiss and English

    ! Autonomic response

    independentof the threat! Memory of the spider -> activation

    of fear response

    ! Can arise with anticipation of thetriggering event

    ! Usually a learned response

    ! Can lower pain thresholdsignificantly! Innocuous stimuli -> interpreted as

    pain

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    ! Several types of anxiety Generalized anxiety disorder

    Panic disorder

    Obsessive-compulsive disorder (OCD) Social anxiety disorder

    Specific phobias (arachnophobia)

    Post-traumatic stress disorder (PTSD)

    Situational stress anxiety****

    Note: May often have additional diagnosis ofdepression

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    General Anxiety Situational Anxiety

    !

    Mood disorder! Anxious but dont know why

    ! Biochemical changes in theCNS

    ! Treatment modalities

    !

    Pharmacotherapeutics

    " Mood stabilizers

    " Antidepressants

    " Anxiolytics

    ! May require larger doses

    !

    Anxious secondary to anevent (dental visit)

    ! Treatment modalities

    ! Non-pharmacotherapeutics

    " Iatrosedation

    "

    Hypnosis! Pharmacotherapeutics

    " Nitrous oxide

    " Anxiolytics

    ! May respond to smaller

    doses

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    Similarities Differences

    !

    Autonomic response! Physical

    ! Emotional

    ! Learned response?

    ! Requires consciousness

    !

    Threat present/not present

    ! Learned response?

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    !

    Goals of Pharmacologic Management

    ! Induce an altered state of consciousness

    " Relative analgesia

    "

    Co-medication

    " Twilight sleep

    " Chemamnesia

    ! Reduce/eliminate stress and anxiety

    Sedation

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    !

    Analgesia:

    ! The diminution or elimination of pain

    !

    Local anesthesia:

    ! Elimination of sensation, especially pain, in one

    part of the body

    " Predictable and reversible

    ! Via topical application or regional injection ofa drug

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    Minimal Sedation (Anxiolysis, Stress reduction):

    ! Minimally depressed level of consciousness

    " Modest impairment of cognitive function and

    coordination" Respond normally to tactile stimulation and verbal

    command

    ! Independently and continuously maintain own

    airway" Airway reflexes intact

    ! NOcardiovascular or respiratory depression

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    Moderate Sedation

    ! Depressed level of consciousness

    " Respond purposefully to verbal commands, either

    alone or with light tactile stimulation! Nointerventions are needed to maintain a

    patent airway

    " Spontaneous ventilation is adequate

    "

    Airway reflex impairment possible! Cardiovascular function is usually maintained

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    Deep Sedation

    ! Depressed level of consciousness" Cannot be aroused easily

    "

    Dorespond purposefully to repeated or painfulstimulation

    ! Ability to maintain patent airway may becompromised" May require airway support

    "

    Airway reflexes impaired" Spontaneous ventilation may be inadequate

    ! Cardiovascular function is usually maintained

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    General Anesthesia

    ! Unconscious

    " Not arousable, not even to painful stimulation

    !

    Respiratory function is often impaired" Airway support/patency may be required

    " Hypopnea/apnea

    " Positive pressure ventilation

    "

    Airway reflexes impaired! Cardiovascular function may be impaired

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    ! Best viewed as a continuum

    ! No defined step to reach a setlevel

    !

    Ability and speed to move alongthe continuum varies greatly

    !"#$%&"'$

    )#%"#$%&"'$

    *+,-

    How high is this plane?

    How far away is it?

    Is it high enough to fly over orunder the sun?

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    Stage I: Induction! Analgesia

    ! Conscious sedation

    Stage II: Excitement!

    UnconsciousStage III: SurgicalAnesthesia

    ! Planes 1-4

    Stage IV: MedullaryParalysis

    !

    Respiratory arrest

    ! Cardiovascularcollapse

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    Dionne, R Drug Interactions and Adverse Effects In: Anesthesia and Sedation in the Dental

    OfficeDionne R and Laskin D (eds). Elsevier 1986 p. 63

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    ! Levels of sedation! What is the main goal

    of the sedation?! What physiologic signs

    are we looking for?

    ! Minimal sedation! Conscious sedation! Anxiolysis

    ! Moderate sedation!

    Deep sedation!

    General anesthesia

    ???

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    !

    History of dental anxiety, fear or phobia! Phobic patient

    !

    Patient management issues! Mentally disability" Alzheimers dementia

    ! Physically disability

    "

    Cerebral palsy" Parkinsons disease

    ! Precooperative children

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    ! Invasive or extensive procedures! Full mouth extraction

    ! Mandibular resection and reconstruction

    ! Physically compromised patients! Ischemic heart disease

    ! Stress-induced asthma

    Need to match the level of sedation with thepatient and the surgical procedure!!!

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    Class Description

    I Normal, healthy patient

    II Mild systemic disease

    III Severe systemic disease that limits activity but is notincapacitating

    IV Incapacitating systemic disease that is a constant threat

    to lifeV Moribund patient not expected to survive 24 hours with

    or without operation

    VI Clinically dead patient kept alive for organ donation

    E Emergency operation*

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    Enteral Parenteral!

    Drug is absorbed throughthe GI tract or oral mucosa

    ! Subject to first passmetabolism

    ! Oral

    !

    Rectal

    ! Sublingual*

    !

    Drug bypasses the GI tract!

    NOT subject to first pass

    metabolism

    ! Intravenous

    ! Intramuscular

    !

    Intranasal

    ! Submucosal

    ! Subcutaneous

    ! Inhalational

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    ! Route DOES NOT determine the depth of sedation

    ! Any route has the potential to induce any degree of sedation or anesthesia*

    ! Route of administration MUST comply with the needs of the surgery and thepatient

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    Providers MUST:

    1. Be able to identify thedepth of sedation

    2. Be able to rescue patientswho become sedateddeeper than the intendedlevel- Reversal of sedation

    3. Be able to manage

    sequela that arise due tothe unintended depth ofsedation- Airway support

    - Cardiovascular support

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    ! 3 As! Anxiolysis! Amnesia! Analgesia

    !

    Cardiovascular and respiratory stability! Quickly alter depth

    ! Rapid, comfortable induction! Rapid, clean emergence

    !

    Postoperative analgesia! No PONV! Inexpensive

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    !

    There is no magic bullet

    !

    Use of balanced anesthetic

    ! Combination of techniques

    !

    Benefit/risk of each drug

    ! Example: Benzo + opioid + LA

    ! The right combination is the one that

    works

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    ! No additional licensing for the following:

    ! Inhalation Minimal Sedation" Nitrous oxide + Oxygen

    ! Enteral and/or Combination Inhalation-EnteralMinimal Sedation

    ! Moderate Enteral Sedation

    ! However, this is likely to change in the nearfuture

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    ! Great for anxiolysis

    ! Includes supplemental

    oxygen

    !

    Easily reversible! If pt is breathing!!!

    ! Can be titrated, even

    with oral sedation

    ! Very safe

    !

    Caution"

    Significant additive sedationand muscle relaxation

    " AIRWAY, AIRWAY, AIRWAY!!!!!

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    Light Parenteral Conscious Sedation Deep sedation

    ! Minimally depressed level ofconsciousness

    ! Maintain own airway

    ! Respond to stimulation

    ! THIS IS OUR GOAL!!! Awake!

    Breathing! Calm! Responsive! Relaxed

    ! Depressed consciousness

    ! Partial loss of protective

    reflexes

    ! Inability to continually

    maintain airway

    !

    Unresponsive to

    stimulation

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    !

    Applicant must meet one of the followingcriteria:

    !

    (1) Graduation from an approved dentalschool which included training in conscious

    sedation techniques at the predoctoral level

    !

    (2) Completion of an intensive postdoctoraltraining program in the use of light parenteral

    conscious sedation

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    ! Satisfactory evidence of completion ofeducational and training requirements means thefollowing:

    !

    (1) Certificate of completion of the educational ortraining program

    ! (2) Official transcript from a board approved dentalschool which clearly designates completion of theeducation or training.

    ! (3) Certificate of completion of a continuingeducation program

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    Requirements:

    !

    Valid Indiana dental license

    !

    Valid LPCS permit

    !

    Provide training certificate

    ! Equipment affidavit

    ! ACLS certified

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    Requirements:

    !

    Valid Indiana dental license

    !

    Valid GA/DS permit

    !

    Provide training program certificate

    " Dental Anesthesiology

    " Oral and Maxillofacial Surgery

    !

    Equipment affidavit! ACLS certified