Introduction to histology C. Jayawardena, Basic Sciences, 08/09/2010
Introduction to histology
C. Jayawardena, Basic Sciences, 08/09/2010
I want you to understand ....I want you to understand .... What is histology? Why do we learn histology?
What is the structural organization of the body?
What do we learn in histology? How are we tested for histology? How do we learn histology? Microscopes References
Histology/ Microscopic anatomyHistology/ Microscopic anatomy
Gross anatomy
Macroscopic anatomy
Developmental anatomy
Clinical anatomy
Surgical anatomy
Pathological anatomy
Why do you learn histologyWhy do you learn histology
The Hierarchy of Structural OrganizationThe Hierarchy of Structural Organization
Creature
Atoms
Organelles
EpitheliumConnective tissueMusclesNervesBones
HeartLungsLiverStomachSkin
CVSRSGISGUSNSIS
The Hierarchy of Structural OrganizationThe Hierarchy of Structural Organization
A group of cells performing a common function
A discrete structure made up of more than one tissue
Organs working together for a common purpose
Cells and their functional subunits Molecule
s
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Normal structure Normal functions Healthy life
Abnormal structure No functionsDiseased
To Objectives
To understand How cells and tissues are arranged in the normal
organ system of the body, and
How these cells and tissues are specialized to perform the functions (structure-function relationship) most effectively.
Why do you learn histologyWhy do you learn histology
What do you learn in histologyWhat do you learn in histology
Learn the (microscopic) structure while Learn the (microscopic) structure while correlating the structure with functionscorrelating the structure with functions
Physiological
Biochemical
Pathological / diseased
Treatment
Prevention
How are you tested for histologyHow are you tested for histology
Theory -o MCQ o SAQ
Practical –o Spots (OSPE)
How are you tested for histologyHow are you tested for histology
BS 1103 – Tissues of the body
BS 1105 –Teeth and supporting
BS 1106 – Cardiovascular
BS 1107 – Respiratory
BS 1108 – Gastrointestinal
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1.1 Identify precisely1.2 Give named example for 1.1 in the body1.3 Identify the structure indicated by the pointer1.4 Give two reasons for your answer in 1.3
How do you learn histologyHow do you learn histology
How do you learn histologyHow do you learn histology
Practical
Come up with idea what you are looking for today e.g What do you expect to see in the stratified
squamous keratinizing epithelium
See those features in the sections by your-self Find answers for the questions Actively involve in the discussion
http://www.lab.anhb.uwa.edu.au/mb140/
Practical
Examination
What do you expect to see in the particular tissue or organ (Preparation)
See those features in the sections by your-self (Practical)
How do they appear
Recall
See features seen in the section
From the features, make a identification
MicroscopesMicroscopes Light microscopy
Polarized microscopy Confocal microscopy Fluorescence microscopy
Electron microscopy TEM – Transmitted EM SEM – Scanning EM
Light microscopyLight microscopy
Gartner and Hiatt. Color Textbook of Histology. 1997.
Maximal resolving power:
(The smallest distance between 2 points at which they can be seen as separate spots)
LM; 0.2µm
Electron microscopyElectron microscopy
Gartner and Hiatt. Color Textbook of Histology. 1997. Figure 1.1.
TEM LMTEM LM
Gartner and Hiatt. Color Textbook of Histology. 1997. Figure 1.1.
ReferencesReferences
http://www.lab.anhb.uwa.edu.au/mb140/