Lecture 3 ETY494 – Introduction to Biomedical Engineering (2019 Spring Semester) MATERIALS SCIENCE AND TECHNOLOGY DEPARTMENT UNIVERSITY OF CRETE
Lecture 3
ETY494 – Introduction to Biomedical Engineering (2019 Spring Semester)
MATERIALS SCIENCE AND TECHNOLOGY DEPARTMENTUNIVERSITY OF CRETE
BME
Examples of BME
Evolution of the modern health care system
Notable figures in BME
Ethics and Morality
Career as BME
2https://www.imoney.sg/articles/career-tips/
7https://www.landolakes.com/recipe/16800/blue-ribbon-apple-pie/
21%
1%
78%
What does the pie represent?
N2
O2
Ar, CO2, etc
A fluid is a collection of molecules that are randomly arranged and held together by weak cohesive forces and by forces exerted by the walls of a container
Will deform under applied pressure A fluid can flow and take the shape of its
container Both liquids and gases are fluids. Mechanics of a fluid
Fluid Statics – fluids at rest Fluid Dynamics – fluids in motion
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AIRPLANE FORMULA 1
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http://scholarspoon.com/brain-drain-a-global-phenomenon/https://www.express.co.uk/news/world/613444/Michael-Schumacher-latest-F1-health-coma-Ferrari-Mercedes
https://www.youtube.com/watch?v=HsgZM2TXXy4
http://www.f1insight.co.uk/2013/04/how-diffuser-exhaust-rear-wing-create-downforce-grip-f1.html
Suppose you are standing directly behind someone who steps back and accidentally stomps on your foot with the heel of one shoe. Would you be better off if that person were:
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(A)1.90m85kg
Casual shoes
(B)1.65m50 kg
High heels shoes
https://www.abc.net.au/news/2017-11-13/why-do-we-wear-high-heeled-shoes/9135936
DIVING CLIMBING MOUNTAIN
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http://www.hispotion.com/3-tips-start-climb-mountains-46841/mountain-climbing-wallpaper-2https://www.padi.com/courses/advanced-open-water
16https://courses.lumenlearning.com/physics/chapter/11-4-variation-of-pressure-with-depth-in-a-fluid/
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If the liquid is open to the atmosphere and P0 is the pressure at the surface of the liquid, then P0 is atmospheric pressure.
P0 =1.00 atm = 1.013 x 105 Pa
Mass=density x Volume =ρV=ρAh
Raymond A. Serway, John W. Jewett - Physics for Scientists and Engineers, Volume 1, Technology Update-Brooks Cole (2015)
Implies that the pressure is the same at all points having the same depth, independent of the shape of the container.
A change in the pressure applied to a fluid istransmitted undiminished to every point ofthe fluid and to the walls of the container.
18https://www.christianitytoday.com/history/people/evangelistsandapologists/blaise-pascal.html
20
http://insightreplay.com/tech-sports-computational-fluid-dynamics/ https://www.carthrottle.com/post/nrgg7j6/
https://www.livescience.com/47446-fluid-dynamics.html https://giphy.com/gifs/paint-mixing-4POEoOBubrNIY
https://media.giphy.com/media/13L8EZXqkZM6xq/giphy.gif
STEADY OR LAMINAR
Each particle of the fluid follows a smooth path such that the paths of different particles never cross each other
In steady flow, every fluid particle
Arriving at a given point in space has the same velocity
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https://www.wardsauto.com/technology/slippery-slope-production-cars-making-jaw-dropping-aerodynamic-gains
Raymond A. Serway, John W. Jewett - Physics for Scientists and Engineers, Volume 1, Technology Update-Brooks Cole (2015)
TURBULENT
Above a certain critical speed, fluid flow becomes turbulent
Turbulent flow is irregular flow characterized by small whirlpool-like regions
22Raymond A. Serway, John W. Jewett - Physics for Scientists and Engineers, Volume 1, Technology Update-Brooks Cole (2015)
Determines whether the fluid flow is laminar or turbulent
Non-dimensional velocity
laminar - when Re < 2300
transient - when 2300 < Re < 4000
turbulent - when Re > 4000
25https://study.com/academy/lesson/reynolds-number-definition-equation.html
YELLOW COLOR BLUE COLOR
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https://graf1x.com/shades-of-yellow-color-palette-chart/ https://graf1x.com/shades-of-blue-color-palette/
The resistance of a fluid to flow The measure of the internal friction of a fluid This internal friction, or viscous force, is
associated with the resistance that two adjacent layers of fluid have to moving relative to each other
Viscosity causes part of the fluid’s kinetic energy to be transformed to internal energy
Applies only in fluids The higher a fluid’s viscosity, the slower it flows
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NEWTONIAN FLUID
A Newtonian fluid's viscosityremains constant, no matter theamount of shear applied for aconstant temperature. Thesefluids have a linear relationshipbetween viscosity and shearstress (Fluids for which theviscosity is independent ofpressure)
Example Water Mineral oil Gasoline Alcohol
NON-NEWTONIAN FLUID
Opposite Example
Ketchup
Paints
Blood
Toothpaste
Shampoo
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The fluid is nonviscous In a nonviscous fluid, internal friction is neglected. An
object moving through the fluid experiences no viscous force
The flow is steady In steady (laminar) flow, all particles passing through a
point have the same velocity The fluid is incompressible
The density of an incompressible fluid is constant The flow is irrotational
In irrotational flow, the fluid has no angular momentum about any point. If a small paddle wheel placed anywhere in the fluid does not rotate about the wheel’s center of mass, the flow is irrotational
35Raymond A. Serway, John W. Jewett - Physics for Scientists and Engineers, Volume 1, Technology Update-Brooks Cole (2015)
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ρ1A1v1 = ρ2A2v2
A1v1 = A2v2 =constant
ρ is the (unchanging) density of the ideal fluid
https://www.pinterest.com.au/pin/820147782114362163/
velocity
States that the sum of all forms of energy influid flowing along an enclosed path is thesame at any two points in that path
Assumptions
Flow is steady
Density is constant (incompressible)
Friction losses are negligible
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𝑃 +1
2∙ ρ ∙ 𝑣2 + 𝜌 ∙ 𝑔 ∙ ℎ = 𝑐𝑜𝑛𝑠𝑡𝑎𝑛𝑡
A venturi creates a constriction within a pipe (classically an hourglass shape) that varies the flow characteristics of a fluid (either liquid or gas) travelling through the tube. As the fluid velocity in the throat is increased there is a consequential drop in pressure
44https://steemit.com/steemstem/@theborges/flow-measurement-venturi-tube
By attaching manometers to three sections of the tube, the pressure drop can be measured and the flow rate through the throat calculated. This is termed a VenturiMeter
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http://instrumentationbasicss.blogspot.com/2017/10/basics-of-venturi-tube.html
From Ancient Greek athḗra (ἀθήρα), meaning 'gruel‘ sklerosis (σκλήρωσις), meaning 'hardening‘
Atherosclerosis is a type of arteriosclerosis. Plaque (fatty deposits) clogs your arteries Made up of cholesterol, fatty substances, cellular
waste products, calcium and fibrin (a clotting material in the blood)
Causes arteries to narrow Less flexible Reduces blood flow Lessens the amount of oxygen and other nutrients
reaching the body
47https://www.heart.org/en/health-topics/cholesterol/about-cholesterol/atherosclerosis
LAMINAR BLOOD FLOW TURBULENT BLOOD FLOW
Constriction of the vessel, or obstruction of the vessel lumen, disrupts laminar flow and leads to turbulent blood flow
Blood flow velocity increases small eddies lead to flow in
directions other than parallel Such current eddies lead to
turbulence Turbulent blood flow is noisy
and can be heard by using a stethoscope placed over the artery
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Blood flows in layers As the layers extend toward
the vessel interior, their velocity increases
laminar blood flow is silent
https://www.physiologyweb.com/figures/physiology_illustration_Gxr9bSdjRij69DSavoTbjWtiQ44Pw3aM_laminar_versus_turbulent_flow_in_blood_vessels.html
How do we measure blood pressure?
52https://omronhealthcare.com/products/5-series-upper-arm-blood-pressure-monitor-bp742n/?bvstate=pg:4/ct:r
https://www.indiamart.com/proddetail/manual-blood-pressure-machine-16038117873.html
Laminar and turbulent flow provide the physical basis for the auscultation method of blood pressure measurement
Using a pressure cuff placed over the upper arm (to cause vessel constriction) and a stethoscope placed over the brachial artery
Listen for the noise of turbulent flow when the vessel is constricted)
The sounds heard by this method are referred to as the Korotkoff's sounds.
53https://www.physiologyweb.com/figures/physiology_graph_kOmgHIRVcRNo0zfrBCKzz1dZcNyZkjeC_measurement_of_hydrostatic_blood_pressure.html
https://www.saga.co.uk/magazine/health-wellbeing/conditions/cardiovascular/how-to-monitor-blood-pressure
SLIPSTREAM
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https://www.formula1.com/
https://hackernoon.com/the-good-the-bad-and-the-ugly-crypto-2018-ba784bdd2a47