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Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost in a Large Cohort of Pregnant Women: The St. Carlos Gestational Diabetes Study Featured Article: Alejandra Duran, Sofía Sáenz, María J. Torrejón, Elena Bordiú, Laura del Valle, Mercedes Galindo, Noelia Perez, Miguel A. Herraiz, Nuria Izquierdo, Miguel A. Rubio, Isabelle Runkle, Natalia Pérez-Ferre, Idalia Cusihuallpa, Sandra Jiménez, Nuria García de la Torre, María D. Fernández, Carmen Montañez, Cristina Familiar, and Alfonso L. Calle-Pascual Diabetes Care Volume 37: 2442-2 450 September, 2014
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Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

Dec 21, 2015

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Randolf Grant
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Page 1: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved

Pregnancy Outcomes at a Lower Cost in a Large Cohort of Pregnant Women: The St.

Carlos Gestational DiabetesStudy

Featured Article:

Alejandra Duran, Sofía Sáenz, María J. Torrejón, Elena Bordiú, Laura del Valle, Mercedes Galindo, Noelia Perez, Miguel A. Herraiz,

Nuria Izquierdo, Miguel A. Rubio, Isabelle Runkle, Natalia Pérez-Ferre, Idalia Cusihuallpa, Sandra Jiménez, Nuria García de la Torre, María D. Fernández,

Carmen Montañez, Cristina Familiar, and Alfonso L. Calle-Pascual

Diabetes Care Volume 37: 2442-2450

September, 2014

Page 2: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

STUDY OBJECTIVE 

• Use of the new International Association of the Diabetes and Pregnancy Study Groups criteria (IADPSGC) for the diagnosis of gestational diabetes mellitus (GDM) results in an increased prevalence of GDM

• Whether their introduction improves pregnancy outcomes has yet to be established

• Cost-effectiveness was evaluated of one-step IADPSGC for screening and diagnosis of GDM compared with traditional two-step Carpenter-Coustan (CC) criteria

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 3: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

STUDY DESIGN AND METHODS

• GDM risk factors and pregnancy and newborn outcomes were prospectively assessed between 24 and 28 weeks of gestation in the following:

• • 1,750 pregnant women from April 2011 to March 2012 using CC criteria

• • 1,526 pregnant women from April 2012 to March 2013 using IADPSGC

• Both groups received the same treatment and follow-up regimes

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 4: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

RESULTS

• Use of IADPSGC resulted in an important increase in GDM rate and an improvement in pregnancy outcomes

• There was a decrease in the rate of:

• Gestational hypertension• Prematurity• Cesarean section• Small-for-gestational-age infants• Large-for-gestational-age infants• Apgar 1-min score <7• Admission to neonatal intensive care unit

• Estimated cost savings was <<Insert symbol from article>>14,358.06 per 100 women evaluated using IADPSGC versus the group diagnosed using CC

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 5: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

CONCLUSIONS

• Application of the new IADPSGC was associated with:

• A 3.5-fold increase in GDM prevalence in our study population

• Significant improvements in pregnancy outcomes

• Cost-effectiveness

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 6: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 7: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 8: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

Duran A. et al. Diabetes Care 2014;37:2442-2450

Page 9: Introduction of IADPSG Criteria for the Screening and Diagnosis of Gestational Diabetes Mellitus Results in Improved Pregnancy Outcomes at a Lower Cost.

Duran A. et al. Diabetes Care 2014;37:2442-2450