www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 20 Retention in care among women initiated on Option B plus in the Antenatal Clinic (ANC) and labour ward at Mulago National Referral Hospital, Kampala Uganda Authors: Emily Namara-Lugolobi, Zikulah Namukwaya, Philippa Musoke, Ayoub Kakande, Joyce Matovu, Sarah Kamya, Medius Kyarimpa,Jennifer Namusobya, Josaphat Byamugisha, Mary Glenn Fowler.
Retention in care among women initiated on Option B plus in the Antenatal Clinic (ANC) and labour ward at Mulago National Referral Hospital, Kampala Uganda . - PowerPoint PPT Presentation
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www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Retention in care among women initiated on Option B plus in the Antenatal Clinic (ANC) and labour ward at Mulago National Referral Hospital, Kampala Uganda
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Introduction
• Globally, paediatric HIV infections have decreased by 43% from 2003 to 2011 (UNAIDS)
• In 2012, The World Health Organisation (WHO) gave interim recommendations for same day HIV testing and triple ARVs for PMTCT (Option B) with consideration of continuing ARVS as treatment for the rest of the woman’s life (Option B+)
• This is regarded by WHO to be a more effective strategy to achieve the UNAIDS’ target of virtual elimination by 2015 compared to previous guidelines.
• Uganda adopted WHO option B+ guidelines in September 2012.
• Potential challenges with this strategy include retention of pregnant and post partum women in long term care; and risk of waning adherence among a generally healthy population of HIV infected pregnant and post partum women who do not yet meet country treatment criteria.
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Introduction
• Retention in care is essential to monitor adverse reactions to ART, adherence and response to treatment
• This is vital to maintain the success of Option B+
• The objectives of this program evaluation were
– To determine the proportion HIV infected pregnant and postpartum women who had returned for the first visit by two, four, six or twelve weeks after initiation on Option B+
– To compare the return rates between those initiated on Option B+ in ANC and at the labour ward.
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Mulago PMTCT Programme• The PMTCT Program at
Mulago National referral Hospital was started in 2000.
• It offers routine “opt-out” same day HIV testing in its 3 antenatal clinics (ANC) and 3 labour wards
• Over 33,000 pregnant women are screened each year and about 10% are HIV Infected
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
The PMTCT Programme
• HIV positive women are enrolled in the PMTCT program and receive comprehensive HIV/AIDS services which include
– Antiretrovirals for PMTCT and treatment
– Management of opportunistic infections
– Cotrimoxazole prophylaxis
– Supportive counselling
– Psychosocial support groups
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Methods: Option B+ implementation in ANC
• The Mulago PMTCT Programme rolled out Option B+ on 17th Oct in the ANC and on 25th Oct 2012 in labour wards
• Women were initiated on ART the same day of HIV diagnosis and given drug supply for one month
• One to two weeks appointment to receive lab results and further comprehensive care
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Methods: Implementing option B+ on the busy labour wards
• HIV infected women identified at labour ward were offered single dose NVP and then counselled to start ART there after
• They were asked to return for CD4 cell count, liver and renal function test results within six weeks after delivery
• This follow-up visit remains critical for evaluation of CD4 cell count, adverse reactions to ART, adherence and supportive counselling, clinical evaluation and management of opportunistic infections
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Methods: Strategies to improve long term retention in care
• Ongoing counselling by midwives and counsellors
• Peer counselling
• Phone calls after missed appointments
• Home visits by peer mothers and a health visitor to those not reached by phone
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Monitoring and Evaluation Methods
• We reviewed data to determine the number of women who were initiated on Option B+ between
– 17th October 2012 and 28th February 2013 in ANC – 25th October 2012 and 28th February 2013 in labour ward
• We also determined the number of women who had returned for the first visit within the first three months after B+ initiation
• The retention rate was determined as • women who returned for the first visit X 100 women initiated on Option B+
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Demographic characteristicsVARIABLE ANC n(%, 95% CI) LABOUR WARD n(%,