Intraoperative-DESI-MS-based Biopsy Analysis Platform for Glioma Diagnosis, Extent of Tumor Cell Infiltration Estimation, and IDH Subtyping Clint Alfaro , Valentina Pirro, Alan K. Jarmusch, Eyas M. Hattab, Aaron A. Cohen-Gadol, R. Graham Cooks Improving Health Through Research indianactsi.org MSACL 2019 Palm Springs, CA MS Imaging in Clinical Applications 1
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Intraoperative-DESI-MS-based Biopsy Analysis Platform for Glioma Diagnosis, Extent of Tumor Cell Infiltration Estimation,
and IDH SubtypingClint Alfaro, Valentina Pirro, Alan K. Jarmusch, Eyas M. Hattab, Aaron A. Cohen-Gadol,
R. Graham Cooks
Improving Health Through Researchindianactsi.org
MSACL 2019 Palm Springs, CA MS Imaging in Clinical Applications
1
Background and introductionOur goal: Develop and evaluate an intraoperativeDESI-MS-based tool to assist neurosurgery byproviding rapid diagnostic information
Gliomas
Claes et al. Acta Neuropathol ,2007, 114:443–458
-Surgical resection is primary treatment
-Grade IV five-year survival rate is 5%
-Residual tumor is primary cause of recurrence Intraoperative MS at IUSM