GLAUCOMA SERVICE ROHIT VARMA, MD, MPH Professor of Ophthalmology and Preventive Medicine To schedule an appointment or for more information about this revolutionary treatment, please call 323.442.6335 or visit us online at USCeye.org USC ROSKI EYE INSTITUTE GLAUCOMA SERVICE The USC Roski Eye Institute Glaucoma Service offers a complete range of diagnostic and treatment services. Patients have access to the latest technologies and surgical interventions. Common patient referral diagnoses include: • Primary open angle glaucoma • Primary angle closure glaucoma • Pseudoexfoliative glaucoma • Neovascular glaucoma SERVICE FACULTY SAHAR BEDROOD, MD, PhD Assistant Professor of Clinical Ophthalmology ALENA REZNIK, MD Assistant Professor of Clinical Ophthalmology GRACE M. RICHTER, MD, MPH Assistant Professor of Clinical Ophthalmology BENJAMIN Y. XU, MD, PhD Assistant Professor of Clinical Ophthalmology USCEYE.ORG ADVANCED MEDICAL IMAGING Early diagnosis and detection of disease progression are crucial in glaucoma management and prevention of vision loss. Optical coherence tomography (OCT) imaging of the retina and optic nerve transformed the way modern ophthalmologists practice. Glaucoma specialists at the USC Roski Eye Institute are investigating clinical applications for the newest advancements in OCT technology. Grace Richter, MD, MPH, studies OCT angiography, a form of OCT that offers high-resolution visualization of the blood vessels around the optic nerve, the primary site of damage in glaucoma. “Anterior segment OCT has major implications for patients who have or are at risk for angle-closure glaucoma. These patients pose a unique clinical challenge, even for experienced glaucoma specialists. Anterior segment OCT could revolutionize the way we diagnose and manage these patients.” — Benjamin Xu, MD, PhD Benjamin Xu, MD, PhD, studies a different form of OCT called anterior segment OCT, which is used to image structures in the front of the eye, rather than the back of the eye. TRANSLATIONAL MEDICINE At the USC Roski Eye Institute and Keck School of Medicine of USC, clinicians and basic scientists work together to study the pathophysiology of an assortment of eye diseases. Sahar Bedrood, MD, PhD, applies molecular biology principles and techniques to answer clinically oriented questions, such as characterizing the three-dimensional structure of fibrils found in pseudoexfoliation syndrome and glaucoma. “Basic science provides clinician- scientists with the tools necessary to study glaucoma and identify novel treatment methods for pa- tients with the disease.” — Sahar Bedrood, MD, PhD LOS ANGELES | BEVERLY HILLS | PASADENA | ARCADIA YOUR VISION IS OUR MISSION—PRESERVE, PROTECT, RESTORE “The XEN Gel Stent is a unique device that conforms to the ocular tissue and provides significant reduction of intraocular pressure. The device is also extremely comfortable for the patient. Because it is less invasive than other traditional glaucoma surgeries, there are fewer side effects and the patients recover more quickly.” — Alena Reznik, MD
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Y O U R V i s i O n i s O U R M i s s i O n — P R e s e R V e , P R O t e c t , R e s t O R e
GLAUCOMA SERVICE
ROHIT VARMA, MD, MPH Professor of Ophthalmology and Preventive Medicine
To schedule an appointment or for more information about this revolutionarytreatment, please call 323.442.6335 or visit us online at USCeye.org
USC ROSKI EYE INSTITUTEGLAUCOMA SERVICE
the Usc Roski eye institute glaucoma serviceoffers a complete range of diagnostic and treatment services. Patients have access to the latest technologies and surgical interventions.
Common patient referraldiagnoses include:• Primary open angle glaucoma• Primary angle closure glaucoma• Pseudoexfoliative glaucoma• neovascular glaucoma
SERVICE FACULTY
SAHAR BEDROOD, MD, PhDAssistant Professor of
clinical Ophthalmology
ALENA REZNIK, MDAssistant Professor ofclinical Ophthalmology
GRACE M. RICHTER, MD, MPHAssistant Professor of
clinical Ophthalmology
BENJAMIN Y. XU, MD, PhDAssistant Professor ofclinical Ophthalmology
USCEYE.ORG
ADVANCED MEDICAL IMAGINGearly diagnosis and detection of disease progression are crucial in glaucoma management and prevention of vision loss.Optical coherence tomography (Oct) imagingof the retina and optic nerve transformed theway modern ophthalmologists practice.glaucoma specialists at the Usc Roski eyeinstitute are investigating clinical applicationsfor the newest advancements in Oct technology.
grace Richter, Md, MPH, studies Oct angiography, a form of Oct that offershigh-resolution visualization of the bloodvessels around the optic nerve, the primarysite of damage in glaucoma.
“Anterior segment OCT has majorimplications for patients who haveor are at risk for angle-closureglaucoma. These patients pose aunique clinical challenge, even forexperienced glaucoma specialists.Anterior segment OCT could revolutionize the way we diagnoseand manage these patients.”
— Benjamin Xu, MD, PhD
Benjamin Xu, Md, Phd, studies a differentform of Oct called anterior segment Oct,which is used to image structures in the frontof the eye, rather than the back of the eye.
TRANSLATIONAL MEDICINEAt the Usc Roski eye institute and Keckschool of Medicine of Usc, clinicians andbasic scientists work together to study thepathophysiology of an assortment of eyediseases. sahar Bedrood, Md, Phd, appliesmolecular biology principles and techniquesto answer clinically oriented questions, suchas characterizing the three-dimensionalstructure of fibrils found in pseudoexfoliationsyndrome and glaucoma.
“Basic science provides clinician-scientists with the tools necessaryto study glaucoma and identifynovel treatment methods for pa-tients with the disease.”
— Sahar Bedrood, MD, PhD
L O s A n g e L e s | B e V e R LY H i L L s | PA s A d e n A | A R c A d i A YOUR VisiOn is OUR MissiOn—PReseRVe, PROtect, RestORe“The XEN Gel Stent is a uniquedevice that conforms to the ocular tissue and provides significant reduction of intraocular pressure. The device is also extremely comfortable for the patient.Because it is less invasive thanother traditional glaucoma surgeries, there are fewer sideeffects and the patients recover more quickly.”
— Alena Reznik, MD
DIAGNOSTIC SERVICESglaucoma-related vision loss most often beginswith the decline of peripheral vision. Peoplesuffering from the condition often do not noticethe effects of their glaucoma until they havelost a significant portion of their sight. glaucomamay be detected early through routine eyeexams. glaucoma specialists examine boththe structure and function of the optic nerve toassess its state of health. the earlier glaucomais detected and treatment is initiated, themore likely visual function can be preserved.At the Usc Roski eye institute, we provideour patients with state-of-the-art diagnosticservices, such as:
• Visual Field testing: standard AutomatedPerimetry and short-WavelengthAutomated Perimetry
• Ultrasound Biomicroscopy• Optical coherence tomography• Optical coherence tomography
Angiography• Anterior segment Optical coherence tomography • corneal Pachymetry• stereoscopic Optic disc Photography• Fluorescein Angiography
the glaucoma service at the Usc Roski eye institute is a team of specialists dedicated topreventing vision loss through high-quality patient care and cutting-edge research.
WHAT IS GLAUCOMA?glaucoma is a disease that leads to the damageof the optic nerve, the part of the eye thatcarries visual information from the retina tothe brain. it is a leading cause of irreversibleblindness worldwide. However, if diagnosedand treated early the loss of vision can beprevented. elevated intraocular pressure (iOP) isa risk factor for glaucoma, but it is not the soledeterminant of who will develop the disease.Other risk factors include family history and priorocular surgeries. At Usc Roski eye institute, wetreat the following conditions:
• Open-angle glaucoma• Angle-closure/narrow Angle glaucoma• congenital and childhood glaucoma• Juvenile Onset glaucoma• glaucoma Associated with Retinal diseases• glaucoma secondary to eye trauma• neovascular glaucoma• glaucoma secondary to steroid Use• Pigmentary glaucoma dispersion• Pseudoexfoliation syndrome• Uveitic glaucoma
gLAUcOMA seRVice
GLAUCOMA TREATMENTSWhen glaucoma is confirmed, our specialists develop a personalized treatment plan. this mayinclude non-invasive treatments such as medicationand lasers, minimally invasive glaucoma surgery(Migs) or an incisional surgical procedure.
Non-Surgical Laser Procedures• Laser trabeculoplasty (sLt)• Laser iridotomy (LPi)• Micropulse transscleral and diode laser
cyclophotocoagulation (cPc)
Minimally Invasive Glaucoma Surgery (MIGS)• istent®
• trabectome• Kahook dual Blade• cyPass Micro-stent
Non-Surgical Laser Procedures• trabeculectomy• glaucoma drainage devices: eX-PRess Ahmed, Baerveldt and Molteno• Femtosecond laser technology
(in combination with cataract surgery)
THE USC DIFFERENCE At Usc Roski eye institute, we pride ourselveson providing our patients with cutting-edgediagnostic and treatment options to optimizevisual outcomes and minimize surgicalrisks and complications. Whether you havepreviously been diagnosed with glaucoma orare suffering symptoms that may indicate thepresence of the disease, our doctors are here toprovide you with care tailored to your specificneeds. All of our physicians are fellowship-trained in glaucoma.
The glaucoma specialists at USC Roski Eye Institute are committed to clinical and scientific research.
TECHNOLOGICAL INNOVATION Ophthalmologists at the Usc Roski eye institute are at the forefront of developing and testing new medical devices for the treatment of glaucoma, including intraocular pressure (iOP) sensors, drug delivery systems, and surgical instrumentation. Rohit Varma, Md, MPH, professor of ophthalmology, played an integral role in the development of the Xen gel stent, an innovative minimally invasive treatment for alleviating high iOP. the Xen is a soft collagen-derived stent that promises to revolutionize modern glaucoma surgery. He worked on designing the device and analyzing outcome data over several years of clinical trials.
“The XEN device is a game changerfor open-angle glaucoma patientswho are unresponsive to maximumtolerated medical therapy.”
— Rohit Varma, MD, MPH
in keeping with their status as national leaders in innovative treatments to prevent blindness,ophthalmologists at Usc Roski eye institute werethe first in Los Angeles to implant the Xen gelstent in patients outside of clinical trials. thesurgeries were performed by Alena Reznik, Md,and sahar Bedrood, Md, Phd, shortly after theXen was approved by the FdA in late 2016.
EPIDEMIOLOGYRohit Varma, Md, MPH, and a team ofresearchers at the Usc Ocular epidemiologycenter conducted the Los Angeles Latino eyestudy (LALes) from 1998 to 2014. the ground-breaking study provided important insights into the ocular epidemiology of adult Latinos aged40 years and older. due to the high incidenceof glaucoma found during LALes, the Us centerfor Medicare now provides glaucoma screeningbenefits to Latinos aged 50 years and older.Varma, Richter, and Xu are conducting similarepidemiological studies in the chinese Americanand African American communities of LosAngeles to better ocular health and eye disease in these populations.
AdVAnces in gLAUcOMA
U s c e Y e . O R g | L O s A n g e L e s | B e V e R L Y H i L L s | P A s A d e n A | A R c A d i A
• Ab interno canaloplasty (ABic)• Xen gel stent• endoscopic
cyclophotocoagulation (ecP)
“You are the most important person to them,when you go, no one else exists...whatever youneed, they are there for you. You feel welltaken cared for medically and emotionally.”
— Vivian
To schedule an appointment or for more information, please call 323.442.6335 or visit us online at USCeye.org
YOUR VisiOn is OUR MissiOn—PReseRVe, PROtect, RestORe
“OCT angiographyhas the potential toimprove our ability to detect glaucomaat an earlier stage. Itis a novel technologyproviding us withfresh insights in to thecauses of open-angleglaucoma.”
— Grace Richter, MD, MPH
Images represent how peripheral vision declines as glaucoma progresses.
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