Insulinoma 2012 30 years experience with diagnosis and treatment Jan Škrha 3 rd Department of Internal Medicine, 1 st Faculty of Medicine, Charles University in Prague 27 th Symposium of the Federation of the International Danube-Symposia of Diabetes Mellitus, Budapest, 28-30th June, 2012
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Insulinoma 2012 30 years experience with diagnosis and treatment Jan Škrha 3 rd Department of Internal Medicine, 1 st Faculty of Medicine, Charles University.
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Insulinoma 201230 years experience with diagnosis and
treatment
Jan Škrha
3rd Department of Internal Medicine,
1st Faculty of Medicine,
Charles University in Prague
27th Symposium of the Federation of the International Danube-Symposia
of Diabetes Mellitus, Budapest, 28-30th June, 2012
CAUSE OF HYPOGLYCEMIA
1. According to pathogenesis
a) decreased glucose production - lack of contraregulatory hormones
- liver or kidney disease, alcohol
b) increased glucose utilisation
- exogenously caused (DM treatment)
- endogenously caused (insulinoma)
2. According to timing of the food ingestion
a) fasting hypoglycemia (!!!)
b) random hypoglycemia during the day
- reactive (functional), postoperative
Hypoglycemia and activation of contraregulatory hormones