INSTITUTE OF ANTIMICROBIAL CHEMOTHERAPY INSTITUTE OF ANTIMICROBIAL CHEMOTHERAPY SMOLENSK STATE MEDICAL UNIVERSITY SMOLENSK STATE MEDICAL UNIVERSITY Roman S. Kozlov Director Roman S. Kozlov Director
INSTITUTE OF ANTIMICROBIAL CHEMOTHERAPYINSTITUTE OF ANTIMICROBIAL CHEMOTHERAPY
SMOLENSK STATE MEDICAL UNIVERSITYSMOLENSK STATE MEDICAL UNIVERSITY
Roman S. Kozlov
Director
Roman S. Kozlov
Director
20002000Establishment of National Scientific Center of the Russian Ministry of Health
of Monitoring Antimicrobial ResistanceEstablishment of National Scientific Center of the Russian Ministry of Health
of Monitoring Antimicrobial Resistance
20152015Organization of WHO Collaborating Centre for Capacity Building on
Antimicrobial Resistance Surveillance and Research initiatedOrganization of WHO Collaborating Centre for Capacity Building on
Antimicrobial Resistance Surveillance and Research initiated
IAC OF SSMU: MILESTONESIAC OF SSMU: MILESTONES
Clinical pharmacology courseClinical pharmacology course19861986
19871987PK laboratory in regional hospitalPK laboratory in regional hospital
Initiation of clinical trialsInitiation of clinical trials19871987
19901990Bioequivalence studies in volunteersBioequivalence studies in volunteers
19991999
Laboratory of molecular microbiology in regional hospitalLaboratory of molecular microbiology in regional hospital19971997
Institute of Antimicrobial Chemotherapyof Smolensk State Medical Academy
Institute of Antimicrobial Chemotherapyof Smolensk State Medical Academy
SCIENTIFIC ACTIVITIESSCIENTIFIC ACTIVITIES
1993-1995, 2 cities
MoscowMoscowSmolenskSmolensk
1995-1997, 9 cities
Saint-Petersburg
Nizhny Novgorod
Krasnodar Yekaterinburg
Kazan
NovosibirskKrasnoyarsk
Saint-PetersburgSaint-Petersburg
Nizhny NovgorodNizhny Novgorod
KrasnodarKrasnodar YekaterinburgYekaterinburg
KazanKazan
NovosibirskNovosibirskKrasnoyarskKrasnoyarsk
1997-2000, 15 cities
Ryazan
Stavropol Tomsk
Ufa
Omsk
Vladivostok
RyazanRyazan
StavropolStavropol TomskTomsk
UfaUfa
OmskOmsk
VladivostokVladivostok
2000-2005, 30 cities
Archangelsk
Volgograd
Voronezh
Irkutsk
Perm
TyumenChelyabinsk
Yaroslavl
Novokuznetsk
Yakutsk
Kovrov
Vologda
Penza
Khabarovsk
ArchangelskArchangelsk
VolgogradVolgograd
VoronezhVoronezh
IrkutskIrkutsk
PermPerm
TyumenTyumenChelyabinskChelyabinsk
YaroslavlYaroslavl
NovokuznetskNovokuznetsk
YakutskYakutsk
KovrovKovrov
VologdaVologda
PenzaPenza
KhabarovskKhabarovsk
MinskMinskMinsk
2005-2015, 50 cities
Kaluga
Kemerovo
Lipetsk Noyabrsk
Orel
Rostov-on-DonSeversk
Tolyatti
Astana
Gomel
DhezkazganKaraganda
Mogilev
Nijnevartovsk
RostovCherepovets
Kiev
DnepropetrovskIzhevsk
Kirov
KalugaKaluga
KemerovoKemerovo
LipetskLipetsk NoyabrskNoyabrsk
OrelOrel
Rostov-on-DonRostov-on-DonSeverskSeversk
TolyattiTolyatti
AstanaAstana
GomelGomel
DhezkazganDhezkazganKaragandaKaraganda
MogilevMogilev
NijnevartovskNijnevartovsk
RostovRostovCherepovetsCherepovets
KievKiev
DnepropetrovskDnepropetrovskIzhevskIzhevsk
KirovKirov
PARTICIPANTS OF IAC MICROBIOLOGICAL PROJECTSPARTICIPANTS OF IAC MICROBIOLOGICAL PROJECTS
Russia
Belarus
Ukraine
Kazakhstan
MoldovaKishinevKishinev
More than 60 local centers in different regions of Russia, Belarus, Kazakhstan, Ukraine and MoldovaMore than 60 local centers in different regions of Russia, Belarus, Kazakhstan, Ukraine and Moldova
AnadyrAnadyr
BarnaulBarnaul
BryanskBryansk
VitebskVitebsk
GrodnoGrodno
KislovodskKislovodsk
MurmanskMurmansk
Naberezhnye ChelnyNaberezhnye Chelny
Nizhni TagilNizhni Tagil
PetrozavodskPetrozavodsk
SamaraSamaraSurgutSurgut
Ulan-UdeUlan-Ude
Khanty-MansyiskKhanty-Mansyisk
The only institution conducting consistent national studies on antimicrobial resistance in Russian Federation
The only institution conducting consistent national studies on antimicrobial resistance in Russian Federation
Federal governmental grants since 2012− 7 -accomplishing annually− 8 - scheduled in 2016
Federal governmental grants since 2012− 7 -accomplishing annually− 8 - scheduled in 2016
SUPPORT ON NATIONAL LEVELSUPPORT ON NATIONAL LEVEL
Speech at the First session of the Council for the Development of Social Innovations of the Russian Federation subject of the Federation Council of the Federal Assembly: “Innovative medicine: challenges and perspectives”, March 2015
Speech at the First session of the Council for the Development of Social Innovations of the Russian Federation subject of the Federation Council of the Federal Assembly: “Innovative medicine: challenges and perspectives”, March 2015
SCIENTIFIC COLLABORATION WITH LEADING DOMESTIC RESEARCH CENTRESSCIENTIFIC COLLABORATION WITH LEADING DOMESTIC RESEARCH CENTRES
Contracts with Federal Agency for Control for Customer Protection and Human Welfare for studies in the field of AB-resistance accomplishment:
2001-2005 – National Program on Study of AB Resistance Mechanisms
2006-2010 – National Monitoring of AB Resistance
2011-2015 – Scientific researches and developments for providing of sanitary and epidemiological safety and decrease of infectious diseases in Russian Federation
Contracts with Federal Agency for Control for Customer Protection and Human Welfare for studies in the field of AB-resistance accomplishment:
2001-2005 – National Program on Study of AB Resistance Mechanisms
2006-2010 – National Monitoring of AB Resistance
2011-2015 – Scientific researches and developments for providing of sanitary and epidemiological safety and decrease of infectious diseases in Russian Federation
Research Institute of Epidemiology & Microbiology named under Gamaleya
Federal Center of External Clinical & Laboratory Studies Quality Control
Institute of New Antibiotics named under Gauze
Central Research Institute on Epidemiology
Research Institute of Pediatric Infections
State Scientific Center on Antibiotics
Research Institute of Physicochemical Medicine
Research Institute of Epidemiology & Microbiology named under Gamaleya
Federal Center of External Clinical & Laboratory Studies Quality Control
Institute of New Antibiotics named under Gauze
Central Research Institute on Epidemiology
Research Institute of Pediatric Infections
State Scientific Center on Antibiotics
Research Institute of Physicochemical Medicine
SCIENTIFIC COLLABORATION WITH LEADING DOMESTIC RESEARCH CENTRESSCIENTIFIC COLLABORATION WITH LEADING DOMESTIC RESEARCH CENTRES
International AB-resistance studies PHE (London, UK)
Hershey Medical Center (Hershey, USA)
Universita’ Degli Studi Di Siena (Siena, Italy)
Hôpital de Bicêtre (Paris, France)
International AB-resistance studies PHE (London, UK)
Hershey Medical Center (Hershey, USA)
Universita’ Degli Studi Di Siena (Siena, Italy)
Hôpital de Bicêtre (Paris, France)
SCIENTIFIC COLLABORATION WITH LEADING FOREIGN RESEARCH CENTRESSCIENTIFIC COLLABORATION WITH LEADING FOREIGN RESEARCH CENTRES
New molecular genetic methods of AB-resistance study development Karolinska Inst., Center for Genomics Research (Stockholm, Sweden)
Epoch Biosciences (Bothell, USA)
New molecular genetic methods of AB-resistance study development Karolinska Inst., Center for Genomics Research (Stockholm, Sweden)
Epoch Biosciences (Bothell, USA)
Students and workers training Fox Chase Cancer Center (Philadelphia, USA)
Students and workers training Fox Chase Cancer Center (Philadelphia, USA)
ESCMID (European Society of Clinical Microbiology and
Infectious Diseases)
ISC (International Society of Chemotherapy)
FEMS (Federation of European Microbiological Societies)
ASM (American Society of Microbiology)
USP (United States Pharmacopeial Convention)
USAID (United States Agency for International Development)
APUA (Alliance for the Prudent Use of Antibiotics)
Urological Association of Asia
ESCMID (European Society of Clinical Microbiology and
Infectious Diseases)
ISC (International Society of Chemotherapy)
FEMS (Federation of European Microbiological Societies)
ASM (American Society of Microbiology)
USP (United States Pharmacopeial Convention)
USAID (United States Agency for International Development)
APUA (Alliance for the Prudent Use of Antibiotics)
Urological Association of Asia
SCIENTIFIC COLLABORATION WITH LEADING FOREIGN SOCIETIES AND ORGANIZATIONSSCIENTIFIC COLLABORATION WITH LEADING FOREIGN SOCIETIES AND ORGANIZATIONS
EDUCATIONAL ACTIVITYEDUCATIONAL ACTIVITY
Since 1999 IAC carried out more than 100 conferences,
international engagement among them, in more than 30 regions of
Russian Federation
Common number of lectures is close to 800, about 30% was
delivered by IAC workers
Number of trainees in each conference
is from 300 till 1200
Since 1999 IAC carried out more than 100 conferences,
international engagement among them, in more than 30 regions of
Russian Federation
Common number of lectures is close to 800, about 30% was
delivered by IAC workers
Number of trainees in each conference
is from 300 till 1200
EDUCATIONAL ACTIVITYEDUCATIONAL ACTIVITY
MICROBIOLOGY WORKSHOPSMICROBIOLOGY WORKSHOPS
TheoryTheory
PracticePractice
MICROBIOLOGY WORKSHOP PARTICIPANTSMICROBIOLOGY WORKSHOP PARTICIPANTS2013
2014
2015
WEB-PORTAL ON CLINICAL MICROBIOLOGY AND PHARMACOLOGY for health-care workersWEB-PORTAL ON CLINICAL MICROBIOLOGY AND PHARMACOLOGY for health-care workers
3.9 thousands unique visits per day in November 2010 3.9 thousands unique visits per day in November 2010
DYNAMICS OF ANTIBIOTIC.ru VISITSDYNAMICS OF ANTIBIOTIC.ru VISITS
Hits in a day per month
Hits in a day per month
13 000
12 00011 00010 000
9 000
8 0007 0006 000
5 000
4 000Jun 13 Sep 13 Dec 13 Mar 14 Jun 14 Sep 14 Dec 14 Mar 15 Jun 15 Sep 15 Dec 15
From 6.1 to 13.0 thousands unique visits per day in 2015 From 6.1 to 13.0 thousands unique visits per day in 2015 Top 10 among 306 scientific & medical sites on rating Yandex.Medicine Top 10 among 306 scientific & medical sites on rating Yandex.Medicine
INFECTIONS.RU
NEW WEB-PORTAL ABOUT INFECTIONS AND DIAGNOSTICS for patientsNEW WEB-PORTAL ABOUT INFECTIONS AND DIAGNOSTICS for patients
DYNAMICS OF INFECTIONS.ru VISITSDYNAMICS OF INFECTIONS.ru VISITS
3 1002 9002 700
2 500
2 3002 1001 900
1 700
1 500Jan 15 Feb 15 Mar 15 Apr 15 May 15 Jun 15 Jul 15 Aug 15 Sep 15 Oct 15 Nov 15
From 1.7 to 2.4 thousands unique visits per day in 2015 From 1.7 to 2.4 thousands unique visits per day in 2015 707.9 thousands unique visits in 2015 707.9 thousands unique visits in 2015
Hits in a day per month
Hits in a day per month
www.ANTIBIOTIC-SAVE.ru
NEW WEB-PORTAL ABOUT RATIONAL ANTIBIOTIC USE for pharmacists, physicians and patientsNEW WEB-PORTAL ABOUT RATIONAL ANTIBIOTIC USE for pharmacists, physicians and patients
PUBLISHING ACTIVITIESPUBLISHING ACTIVITIES
IAC PUBLICATIONS IN INTERNATIONAL JOURNALSIAC PUBLICATIONS IN INTERNATIONAL JOURNALS
PERIODICALSPERIODICALS
Publishing since 1999
quarterly
Peer-reviewed
Included to Higher
Attestation Commission list
from 2002
International review
Print-out - 2,500-3,000
Publishing since 1999
quarterly
Peer-reviewed
Included to Higher
Attestation Commission list
from 2002
International review
Print-out - 2,500-3,000
PUBLISHING ACTIVITIESPUBLISHING ACTIVITIES 6 full-text practical guidelines
«Clinical Microbiology and Antimicrobial Chemotherapy» journal
36 guides and manuals
Articles in peer-reviewed journals
Presentations and abstracts from Russian and international conferences
Circulars
Textbooks and manuals for students
6 full-text practical guidelines
«Clinical Microbiology and Antimicrobial Chemotherapy» journal
36 guides and manuals
Articles in peer-reviewed journals
Presentations and abstracts from Russian and international conferences
Circulars
Textbooks and manuals for students
Guidelines on antimicrobial
chemotherapy
Total print-out – 55,000 copies
Sent to doctors from 63 Russian regions and other
Russian-speaking countries free of charge
Guide on Infection Control in Hospitals
2003
Print-out - 15,000 copies
2004. Educational Association Approval. Print-out - 500 copies
2005. Educational Association Approval. Print-out - 500 copies
FUTURE DIRECTIONSFUTURE DIRECTIONS
х Erorrs in detecting of antimicrobial resistanceх Imprecision of results with IAC laboratory Valid diagnostics by local laboratory Training of laboratories stuff Evaluation of laboratories facility and consumables equipment levelCollection of nosocomial strains by local laboratories in different citiesOrganization of accredited laboratories networkin different regions
abCloud: THE PRINCIPLEabCloud: THE PRINCIPLEStrains identification by local laboratory
!
!
!
! !
!
Strains and identification data transfer to IAC
Smolensk
Strains reidentification in IAC laboratory
! Accreditation of local laboratory
Х
Х
Fast informing about current state of antimicrobial resistance in different regions
Smolensk
Х
Х
On-line access to server for accreditated laboratoriesAutomated tests results transfer to IAC serverSoftware data processing with automated graphic projection on antimicrobial resistance map Free map access to any user
www.antibiotic.ru
Innovative informational system for healthcare specialists and population
Single innovative data baseabCloud: THE RESULTabCloud: THE RESULT
abCloud REPORTING DATA:MAP OF ANTIMICROBIAL RESISTANCE IN RUSSIAabCloud REPORTING DATA:MAP OF ANTIMICROBIAL RESISTANCE IN RUSSIA
RESISTANCE TO ANTIMICROBIALS –GLOBAL THREAT TO MANKINDRESISTANCE TO ANTIMICROBIALS –GLOBAL THREAT TO MANKIND
NO ANTIBIOTICS…NO CURE