Institute Lectureships

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http://careers.bmj.com/careers/view-job.html?id=9979

Advert number: 168151-0

Posted Date: 09/06/08 Closing Date: 18/07/08

National Institute for Health Research

NIHR Biomedical Research Centrefor OphthalmologyMoorfields Eye Hospital NHS Foundation Trustand UCL Institute of OphthalmologyCity Road, London EC1V 2PD

CLINICAL LECTURESHIP IN OPHTHALMIC

TRANSLATIONAL RESEARCH REF: D4/91The National Institute of Health Research (NIHR) Specialist Biomedical ResearchCentre (BMRC) at Moorfields Eye Hospital/UCL Institute of Ophthalmology is one ofsix new specialist BMRCs in the UK. The partnership has an outstanding trackrecord of basic biomedical research, much of which has led to translational programmes andinnovations that have already benefited large numbers of patients inthe United Kingdom and around the world. The juxtaposition of a huge andunique clinical resource at one of the largest and the longest established eye hospitalsin the world, together with one of the largest eye research institutions with40 academic staff, has led to a wide range of ground breaking biomedical researchfirmly embedded in an appreciation of important clinical problems. The site is oneof the most productive and pre-eminent ophthalmological research sites in theworld. The Moorfields Eye Hospital/UCL Institute of Ophthalmology BMRC focuseson five research themes: Age-related macular degeneration, Diabetes, Glaucoma,Ocular Surface Disease, and Paediatric Ophthalmology and Inherited Eye Disease.This is not exclusive for applicants.

http://www.nihr.ac.uk/

We are seeking to appoint four Clinical Lecturers to posts in 2009 (with 2 furtherposts to be advertised in the future) to undertake translational biomedicalresearch in both clinical and research settings included within the Centre. The successfulcandidates will need to be undertaking a higher degree (PhD/MDRes) which

must be completed and awarded by the commencement of the post. The individualswould write a research programme and would be expected to seek an academicpartner in research, probably from the UCL Institute of Ophthalmology, withwhom the research project will be undertaken jointly. The appointments will beforfour years duration.

The training programmes for these lectureships have been selected throughnational competition to provide high quality academic training for individuals inspecialist training who can demonstrate that they have outstanding potential fordevelopment as a Clinical Academic in research and/or education. These ST5 levelAcademic Clinical Lectureship posts allow the successful candidates to divide theirtime 50:50 between clinical training and undertaking research. It is expected that

over the four year appointment the successful candidates will complete their clinicaltraining on the North Thames Ophthalmology rotation to obtain their CCT,

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whilst also spending 50% of their time in both clinical and laboratory basedresearch under the guidance of their Academic Supervisor.

Please apply online for this position atwww.jobs.nhs.ukwhere you can downloadthe job description and person specification.

It is essential that applicants complete the online application form in full.

Closing date for applications: Friday 18 July 2008

Successful candidates are expected to take up their posts by 1st August 2009.

Working Towards Equality of Opportunity

POSITIVE ABOUT DISABLED PEOPLE

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http://www.jobs.nhs.uk/cgi-bin/vacdetails.cgi?selection=912029160

NIHR Biomedical Research Centre for OphthalmologyMoorfields Eye Hospital NHS Foundation Trust andUCL Institute of OphthalmologyCity RoadLondon EC1V 2PD

Ref: D4 /91

Clinical Lectureship in Ophthalmic Translational Research

The National Institute of Health Research (NIHR) Specialist Biomedical Research Centre(BMRC) at Moorfields Eye Hospital / UCL Institute of Ophthalmology is one of six newspecialist BMRCs in the UK. The partnership has an outstanding track record of basic

biomedical research, much of which has led to translational programmes and innovations thathave already benefited large numbers of patients in the United Kingdom and around theworld. The juxtaposition of a huge and unique clinical resource at one of the largest and thelongest established eye hospitals in the world, together with one of the largest eyeresearch institutions with 40 academic staff, has led to a wide range of ground breaking

biomedical research firmly embedded in an appreciation of important clinical problems. Thesite is one of the most productive and pre-eminent ophthalmological research sites in theworld. The Moorfields Eye Hospital / UCL Institute of Ophthalmology BMRC focuses onfive research themes: Age-related macular degeneration, Diabetes, Glaucoma, Ocular SurfaceDisease, and Paediatric Ophthalmology and Inherited Eye Disease. This is not exclusive for

applicants.

We are seeking to appoint four Clinical Lecturers to posts in 2009 (with 2 further posts to beadvertised in the future) to undertake translational biomedical research in both clinical andresearch settings included within the Centre. The successful candidates will need to beundertaking a higher degree (PhD/MDRes) which must be completed and awarded by thecommencement of the post. The individuals would write a research programme and would beexpected to seek an academic partner in research, probably from the UCL Institute ofOphthalmology, with whom the research project will be undertaken jointly. The appointmentswill be for four years duration.

The training programmes for these lectureships have been selected through nationalcompetition to provide high quality academic training for individuals in specialist trainingwho can demonstrate that they have outstanding potential for development as a ClinicalAcademic in research and/or education. These ST5 level Academic Clinical Lectureship postsallow the successful candidates to divide their time 50:50 between clinical training andundertaking research. It is expected that over the four year appointment the successfulcandidates will complete their clinical training on the North Thames Ophthalmology rotationto obtain their CCT, whilst also spending 50% of their time in both clinical and laboratory

based research under the guidance of their Academic Supervisor.

Please apply online for this position at www.jobs.nhs.uk where you can download the jobdescription and person specification. It is essential that applicants complete the online

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application form in full.

Closing date for applications: Friday 18th July 2008Successful candidates are expected to take up their posts by 1st August 2009.

WORKING TOWARDS EQUALITY OF OPPORTUNITYJump to Apply Now

More informationYou can view more information about this employer and this vacancy by clicking on any ofthe Job Pack Documents or Further Links below. Clicking a link will open a pop-up windowcontaining the relevant details. You may view, print or download the details from there.

Documents

Job Description (67 KB)

Person Specification (54 KB)

Additional Document (67 KB)

Further Links

Trust web site

CRB CheckThis post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and assuch it will be necessary for a submission for Disclosure to be made to the Criminal RecordsBureau to check for any previous criminal convictions.

UK RegistrationApplicants must have current UK professional registration. For further information please

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MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST &

UCL INSTITUTE OF OPHTHALMOLOGY

JOB DESCRIPTION

UKCRC/MMC NIHR INTEGRATED ACADEMIC TRAINING (IAT)

CLINICAL LECTURER

NIHR BIOMEDICAL RESEARCH CENTRE

Moorfields Eye Hospital Background Information

MoorfieldsEye Hospital NHS Trust is a teaching hospital managed by a Trust Board

appointed by the Secretary of State. The Hospital is closely associated with the

adjacent UCL Institute of Ophthalmology and this association fosters a unique

mixture of teaching and research.

The Hospital has a 24-Hour Accident and Emergency Department, modern and wellequipped Operating Theatres, an extensive Outpatient Department and a wide range

of clinical and non-clinical support services. Moorfieldsalso has eleven Community

Eye Service Units which provide community based Primary Ophthalmic Care and

Specialist Services. Patients are referred from the surrounding catchment area, but

additionally both the Hospital and Institute provide a nationwide service for

consultation and treatment of rare or complex cases.

Consultant Physicians hold weekly clinics in general medicine and neurology and

there are close links with the National Hospital for Neurology & Neurosurgery

through these consultants. There is a joint Consultant Radiologist who is also on the

staff of the National Hospital, Queen Square.

The Hospital has an Ophthalmology training programme for SpRs / OSTs who are

based within the North Thames Ophthalmology Rotation. SpRs / OSTs are attached

to the Specialist Service Groups for periods of four months at a time.

UCL Institute of Ophthalmology Background information

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The UCL Institute of Ophthalmology is a dedicated eye research centre associatedwith Moorfields Eye Hospital, committed to investigating the causes of eye diseaseand the development of new therapies. Forty-one academic staff are employedacross twelve Divisions, encompassing Cell Biology, Visual Science, MolecularGenetics and others. The Institute received a 5* rating in both the last two research

assessment exercises conducted by HEFCE (in 1996 and 2001), and has thereforereceived double 5* recognition from HEFCE, demonstrating a sustained level ofresearch excellence.

The National Institute for Health Researchs Biomedical Research Centre forOphthalmology is based at MoorfieldsEye Hospital NHS Foundation Trust and the UCLInstitute of Ophthalmology. Established in April 2007, the centre is funded by theDepartment of Health via theNational Institute for Health Research. The objective of theCentre is to conduct 'translational research' that is designed to take advances in basic medicalresearch from the laboratory to the clinic, enabling patients to benefit more quickly from newscientific breakthroughs. The research of the Centre falls within five major research

themes: Age-related Macular Degeneration, Diabetes, Glaucoma, Ocular Surface Disease,Paediatric Ophthalmology and Inherited Eye Disease.

Our centre is one of 11 biomedical research centres in the UK that were awarded to NHS-university partnerships having an outstanding international reputation for medical researchand expertise, and experience of translating research into the clinical setting.

For further information please see use the following web links:

www.ucl.a c.uk/ioo

www.moorfields.nhs.uk

www.moorfields.nhs.uk/Healthprofessionals/Biomedicalresearchcentre

The Post

This vacant posts are available from 1st August 2009for a period of 4 years.

Applicants will be expected to have completed their Ophthalmology training to a mid

or Higher level (at least 3rd year SpR/OST5) and be in possession of a relevant

Higher degree (eg PhD, MD Res or equivalent).

Over the period of the year it is envisaged that around 50% of the post holders timewill be spent on clinical training and 50% on research.

Research duties will include:

1. Full management of patients attending hospital clinics / casualty departmentsas required

2. Preparation and upkeep of research material, equipment and laboratoryspace

3. Feedback about, and audit of, research process4. Development of a programme of research that could ultimately result in

publications in high-rating, peer-reviewed academic journals

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5. Seeking grant support6. Development and maintenance of national and international research links7. Contribution, where appropriate, to the development of research programmes

in line with the joint sites research mission

Clinical duties will include:

1. The post holder will be required to attend specified clinics and surgical lists2. Management of patients presenting during the week.3. Supervision of junior medical staff in the Service and participation in informal

and formal clinical teaching.4. There will be opportunities for undertaking research and audit

The clinical duties of this post are to be undertaken in a manner satisfactory to the

Service Director. Clinical Lecturers are responsible to members of the Consultant

and Honorary Consultant Staff at MoorfieldsEye Hospital NHS Foundation Trust and

to the Academic Supervisory Staff at the UCL Institute of Ophthalmology. They may

also expect to work in close association with Fellows, OSTs, as well as members of

various departments within the Institute of Ophthalmologynot directly related to their

research. They are expected to liaise closely with members of the nursing staff

regarding patient management (including those attending the Accident and

Emergency Department); and to co-operate with other professional and technical

staff, including Orthoptists and Optometrists. Clinical Lecturers are expected to

undertake teaching duties in the management of patients (including those attending

the Accident and Emergency Department) with regard to junior and non-traininggrade medical staff, orthoptic students and other professional and technical staff in

training. They are expected to take an active part in Audit meetings.

Programme

Clinical Lecturers will attend general and specialist clinics at Moorfields Eye Hospital,

City Road (or elsewhere within the North Thames Ophthalmology rotation) according

to the junior doctors 4 month rotations between the specialist services.

Working emergencies and unforeseen circumstances

Clinical Lecturers are expected to perform duties in clinical emergencies and

unforeseen circumstances at the behest of their Service Consultant. They will also

participate in emergency procedures to deal with fires, floods, security risks and the

like as directed by the Chief Executive.

It has been agreed between the profession and the Department of Health that, whilejuniors accept that they will perform such duties, additional commitments arising

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under this sub-section are exceptional and that junior staff should not be required to

undertake work of this kind for prolonged periods or on a regular basis.

Study and training

Study leave is granted prospectively (on the basis that at least 2 months notice is

given) by the Study Leave Committee, following Consultant approval, and subject to

agreement by the Clinical Management Board.

Main conditions of service

The post is covered by the Terms and Conditions of Service for Hospital Medical and

Dental Staff (England and Wales) and General Whitley Council Conditions of Service

with the exception of paragraph 190 and may be amended from time to time by theTrust.

Salary

The salary range is between 28,352 to 44,581 per annum plus a London

Weighting of 2,162 per annum.

Annual leave entitlement

Six weeks per year by agreement with the Teaching and Service Directors.

Conditions of appointment

The Clinical Lecturer Person Specification contains information regarding required

qualifications and eligibility. In addition, appointees will have membership of a

Medical Defence Organisation. The required notice period is available on request

from the Personnel Department.

No Smoking Policy

The Hospital operates a no smoking policy and all staff are asked to comply with this

and to promote it at all times.

Facilities

A well stocked library offers comprehensive sections on all aspects of ophthalmology

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and is available to all medical staff.

There is a subsidised staff restaurant in addition to a cafeteria and shop run by the

Friends of Moorfields.

Rehabilitation of Offenders Act

Because of the nature of the work for which you are applying, this post is exempt

from the provisions of Section 4 (2) of the Rehabilitation of Offenders Act 1974

(Exemptions) order 1975. Applicants are, therefore, not entitled to withhold

information about convictions which for other purposes are "spent" under the

provisions of the Act, and in the event of employment, any failure to disclose such

convictions could result in dismissal or disciplinary action by the Authority. Any

information given will be completely confidential and will be considered only in

relation to an application for positions to which the order applies.

Applications

Application is via online application at the NHS Jobs Recruitment site at

www.jobs.nhs.uk Ifyou experience any problems, please contact the Personnel

Department (020 7566 2041 / 2430 / 2043). Descriptions of the clinical training and

service requirements will be available from the Personnel Department once start

dates are finalised, according to the rotational placements for the specialist services.

As attachments cannot be made to the on line application form you will need

to email the following documents to [email protected]. Please

ensure that all emails and documents contain the following:-

a. your nameb. job reference D4 / 91c. the reference number on your application form which will start with AR

The additional documents you are required to send to the above Personnel

email address are:

A Research proposal. Applicants should view the BMRCs website for the listof research areas and academic supervisors available to Clinical Lecturers.Applicants are encouraged to contact a prospective supervisor in advance of

submitting an application. The research proposal should outline the researchquestion the Clinical Lecturer intends to explore, the facilities for which s/he is

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likely to need access (for example, patient cohorts, research equipment), andthe benefits for patients that might arise from the research. The researchproposal should be no longer than 2 pages.

The name of the proposed research supervisor you have chosen.

The completed Supplementary Questions For Candidates Applying For A

Clinical Lectureship As Part Of Integrated Academic Training form.

http://www.nihr.ac.uk/

Please contact Louise Halfhide, Administrator for the NIHR Biomedical Research

Centre for Ophthalmology, with informal enquiries via email:[email protected]

Professor Peng Khawis the Director of the NIHR Biomedical Research Centre for

Ophthalmology, and Director of the Clinical Lecturer programme. He may be

contacted via his secretary on 020 7253 3411 ext 2334.

Closing date for receipt of applications is:- Friday 18th July 2008

MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST &

UCL INSTITUTE OF OPHTHALMOLOGY

CLINICAL LECTURER

TRAINING PROGRAMME DESCRIPTION - NIHR BIOMEDICAL RESEARCH

CENTRE, UKCRC/MMC INTEGRATED ACADEMIC TRAINING

Objectives of Academic and Clinical Training:

The objective of the academic training is to allow the trainee to consolidate and build

on their relevant Higher Degree training and develop their research skills to the point

where they can achieve a successful independent research career. The objective of

the clinical training is to achieve the clinical skills necessary within a structuredclinical training programme enabling them to work as a consultant ophthalmologist in

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the UK. It is anticipated that most of the candidates for the lectureships will usually

enter at a mid or higher level of training (ie SpR3 / OST 5).

Training support, location, infrastructure and protected time for research and

education:

The Lecturer will have an honorary contract with UCL, which provides full access to

post doctoral courses and lectures, training, laboratory space, libraries and other

facilities, and will have study leave for meetings and courses. It is expected that the

Lecturers will be associated with one of the many major research groups at the UCL

Institute of Ophthalmology and interact with the other researchers. The Lecturers will

have recourse to internal peer review for papers and grant applications before

submission. Research time for Lecturers will be fully protected by doing alternate

clinical and research periods. During the equivalent clinical weeks, there will be a

balanced programme including 3 sessions for education, study and administration as

recommended by the Royal College of Ophthalmologists who have approved this

timetable

Mentoring arrangements for each trainee:

Each trainee will have a named clinical and scientific mentor. This can be the same

person if appropriate. Each Lecturer will have more informal quarterly meetings and

a formal annual clinical and academic review (jointly if there are separate clinical and

academic mentors).

Milestones and assessment:

The academic milestones for the trainees will include progress in their research

programme as delineated during early review meetings, publications in good

journals, and progress in obtaining grant support.

Individual needs of the Lecturer, quality of training, and academic mobility:

The mentoring system with regular reviews should ensure each Lecturer has a

suitable training scheme. This system will monitor the quality of both scientific and

clinical training. The curriculum is in essence broad based but can be tailormadein a

number of ways, as it is for other ophthalmic trainees. If the RITA process identifies a

training need, targeted training would be undertaken in that area - the Specialist

Training Committee would organise this. Each Lecturer will continue rotating through

the four month clinical attachments, doing alternate clinical and academic weeksuntil he/she attains a Certificate of Completion of Specialist Training. During this

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time, the Lecturer will also be mentored to apply for post-doctoral training support eg.

Clinician Scientist awards from sponsors such as WellcomeTrust and the Medical

Research Council.

Parameters/requirements

Acquire resources and financial support consistent with a double 5*-rated

institution.

Develop and ultimately undertake an independent research programme

complementary to the overall research strategy of the Division and the Institute.

Develop and maintain national and international research links and a high profile

in their field.

Maintain an output of publications using well-regarded means, such as in high-

rating peer-reviewed academic journals, reputable publishers, and conference

proceedings. Contribute their special expertise to the development of research programmes

that meet the mission of the site and to play a significant role in regular researchgroup meetings.

Ultimately supervise postgraduate students engaged in research, postdoctoral

research workers and research assistants, as appropriate

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MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST &

UCL INSTITUTE OF OPHTHALMOLOGY

NIHR BIOMEDICAL RESEARCH CENTRE

UKCRC/MMC NIHR INTEGRATED ACADEMIC TRAINING (IAT)

Person Specification

Clinical Lecturer

ESSENTIAL DESIRABLE METHODS TO

TEST FIT TO

THESE

CRITERIA

QUALIFICATIONS

&

ELIGIBILITY

GMC registration

MB BS (or equivalent)

MRCOphth / FRCS or

FRCS (Ed) or equivalent

Relevant Higher Degree,

PhD or MD Research orequivalent

Evidence of achievement ofFoundation competenciesor equivalent, in line withGMC standards/GoodMedical Practice including:

Good clinical care

Maintaining good medical practice

Good relationships and

communication with patients

Good working relationships with

colleagues

Good teaching and training

Professional behaviour and

Probity

Delivery of good acute clinical

care

Evidence of good progress

in clinical training and that

completion of specialtytraining may beaccommodated either

Other degrees awarded

Extracurricular activities/

achievements relevant toophthalmology

Application form

Interview

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ESSENTIAL DESIRABLE METHODS TO

TEST FIT TO

THESE

CRITERIAduring or after the 4 yearperiod of the CL award

Eligibility to work in the UK

CLINICAL

EXPERIENCE

In possession of an

NTN

Wide experience of

intraocular surgery,equivalent to Year 3 of SpRtraining / OST5.

Experience in other

related specialities

Application form

ACADEMIC/

RESEARCH

Understanding of the principles of

research

Demonstration of understanding

and commitment to academiccareer

Indication of medium and long-

term career goals

Demonstration of a keen interest in

the research element of the CLprogramme

Demonstration of understanding of

the principles of audit andresearch; evidence of participationin audit

Demonstration of the potential for

scientific independence and theability to lead a research team

research

experience,presentations,publications,prizes and

honours Evidence of

previous researchgrants awarded

Evidence of

activeparticipation inaudit

Application form

Interview

CLINICAL SKILLS

Appropriateknowledge baseand capacity toapply sound clinicaljudgement

understanding of

clinical riskmanagement

competent to work

without direct supervisionwhere appropriate

clear, logical thinking

showing an

analytical/scientificapproach

good manual dexterity

and hand/eye co-ordination

up to date and fit to

practise safely

Application form

References

appropriate level of

clinical knowledge

shows knowledge of

evidence informed practice

shows awareness of

own limitations

Demonstration ofacquisition of the level of

demonstrate

s breadth ofexperience andawareness in andoutsidespecialty/medicine

demonstrate

s use of evidence

Application form

Interview

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ESSENTIAL DESIRABLE METHODS TO

TEST FIT TO

THESE

CRITERIA

KNOWLEDGE

knowledge and skillsnecessary for theachievement of Foundationand clinical (matched to theentry level) competenciesor equivalent

informed practice

Knowledgeof the centrehosting theresearch and howthis is best placedto support theresearch,education andtraining needs

Prizes or

distinctions

Presentation

of work at a

national orinternationalmeeting

ORGANISATION &

PLANNING

Ability to organise

oneself & own work andprioritise clinical need

Capacity to manage

time and informationeffectively

understandin

g of NHS, clinicalgovernance &resourceconstraints;management/financial awareness;experience ofcommittee work

information

technology skills

Application form

Interview

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ESSENTIAL DESIRABLE METHODS TO

TEST FIT TO

THESE

CRITERIA

PERSONALSKILLS

Communication &

language skills:All applicants to have

demonstrable skills in written

and spoken English that are

adequate to enable effective

communication about

medical topics with patients

and colleagues which could

be demonstrated by one of

the following:

a) that applicants have undertaken

undergraduate medical training in

English; or

b) have the following scores in the

academic lnternational English

Language Testing System (IELTS)

Overall 7, Speaking 7, Listening 6,

Reading 6, Writing 6.

Ability to build rapport, listen,

persuade, negotiate

uses a non-judgmental approach

to patients and colleagues

regardless of their sexuality,ethnicity, disabil ity, religiousbeliefs or financial status

the ability to produce

legible notes Application form

Interview

References

Decisiveness/accoun

tability: ability to takeresponsibility, showleadership, makedecisions, exert appropriateauthority, capacity to uselogical/lateral thinking tosolve problems and makedecisions

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ESSENTIAL DESIRABLE METHODS TO

TEST FIT TO

THESE

CRITERIA

Interpersonal skills,

managing others andteam involvement: seepatients as people,empathise, work co-operatively with others inmulti-professional teams,open and non-defensive,sense of humour, self-starter, motivated, showscuriosity, initiative

Flexibility: able to

change and adapt, respondto rapidly changing

circumstances Resilience: able to

operate under pressure,demonstrates initiative,cope with setbacks, self-aware

Thoroughness: is

well prepared, shows self-discipline/commitment, ispunctual and meetsdeadlines

Probity: displays

honesty, integrity. Capacity

to take responsibility forown actions anddemonstrate a non- judgemental approachtowards others, aware ofethical dilemmas

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SUPPLEMENTARY QUESTIONS FOR

CANDIDATES APPLYING FOR A CLINICAL LECTURESHIP AS

PART OF INTEGRATED ACADEMIC TRAINING

Academic Achievement and Professional qualifications

University (ies) attended. Please also indicate the Department or School. Dates

Shortlisted candidates will be required to bring original certificates to the interviews

Degree/Diploma (include BSc, BDS,BChD, MBBS, MSc, MB/PhD, PhD,MD or equivalent) state class ofdegree awarded, where appropriate.

Awarding Body Date of Qualification

Prizes and other academic

distinctions

Awarding Body Date of Award

Key and Relevant Academic Achievements

Prizes or other academic distinctions. Please provide any relevant additional information to that provided above.

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Describe your PhD research. Include a brief description of your main findings and their impact and the researchmethods you used (up to 750 words).

Please describe any research training that you have received to date, for example, training courses in research

methods (up to 250 words).

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Publications (short-listed candidates will be asked to bring copies of all peer-reviewed publications to theinterview).

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Presentations/posters at national or international conferences (indicate whether national or

international).

Other Relevant Experience

Please provide brief description of any teaching experience you have had. You may include experience gainedoutside of medicine/dentistry.

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Please give examples and brief details of experience you have had of management or leadership.

Aims, Career Objectives, and Commitment to a career in Academic Medicine/Dentistry

Please indicate your medium and long-term career goals in relation to an academic career.

If you are successful in gaining a Clinical Lectureship, please describe how you will manage the completion of

your clinical training.

Please explain how the hosting research department will support your research aims and career objectives.

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Any further information relevant to an application for a Clinical Lectureship

Please provide any further information that you feel is relevant to this application, in particular, areas that havenot been covered elsewhere. Please state what skills and attributes you will bring to this position and how you

meet the selection criteria.

Academic Referees

Name, job title and address of at least two referees, one of whom should be able to comment on your suitabilityfor a Clinical Lectureship.

1

Telephone Number

Fax Number

Email address

2

Telephone Number

Fax Number

Email address

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Guidance Notes for completion of the Supplementary Questions for

candidates applying for a Clinical Lectureship as part of Integrated

Academic Training

These Guidance Notes are for candidates applying for an IAT Clinical Lectureship.

In addition to the application form please ensure that you meet the criteria in the

Person Specification for a Clinical Lectureship and eligibility criteria outlined in

the paper Clinical Lectureships: Entry, Eligibility, and Exit Points in from August

2007 which can be downloaded from the National Co-ordinating Centre for

Research Capacity Developments (NCCRCD) website at

http://www.nccrcd.nhs.uk.

Academic Achievement and Professional Qualifications

University ( ies ) attended

Please provide the name of the university or universities that you have attended

with dates where you gained your professional or academic qualifications. For

each, please name the Department or School where you were based for your

study.

Degree/Diplomas

Please provide all the qualifications that you have achieved which you feel are

relevant to your application for a Clinical Lectureship. Where a class or grade was

associated with your qualification, please provide this information. The date and

awarding body of your qualification(s) should also be provided. Please note that

original certificates will be requested at interview.

Prizes or other academic distinctions

Please list any prizes or academic distinctions (maximum of six) which you have

gained and provide the date of award and the awarding body for each.

Key and Relevant Academic Achievement

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Prizes and other academic distinctions

This section gives you the opportunity to provide further detail about the prizes

or distinctions you have achieved. Please select those that are relevant to your

application for a Clinical Lectureship and briefly describe what you did in order to

be recognised with a prize or distinction.

Describe your PhD research

This section gives you the opportunity to describe the research you completed

for your PhD. Please include a brief description of your main findings and the

impact these have had. Examples of impact could include:-

Contribution of research to practice, diagnosis, treatment or managementof patients;

Contribution of research to the understanding of a disease process;

Changes to a service (e.g. a referral pathway); and

Translation of a research finding or development into clinical practice (e.g.a diagnostic tool)

Please also give details of the research methods that you used. Please do not

exceed the 750 word limit.

One other significant research project

This section provides you with the opportunity to give details about one other

significant research project, other than your PhD, that you have been involved in.

You only have 250 words, but please give brief details about the project, the

methods you used and you exact role in and contribution to the project overall.

Publications

Please list all your publications. Please note that short-listed candidates will be

required to provide copies of their peer-reviewed publications at interview.

Presentations/posters

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Please provide details of any posters or presentations you have given at both

national and international conferences. Please make it clear which are national

and which are international.

Other Relevant Experience

Teaching experience

Please describe any experience you have of teaching and indicate where this is

relevant to research. You may also include examples outside of

medicine/dentistry.

Management or leadership

Please give examples and brief details of the experience you have had of

developing your management or leadership skills.

Aims, Career Objectives and Commitment to a Career in Academic

Medicine/Dentistry

Medium and long-term career goals

Please indicate your medium and long-term goals in relation to academic

medicine/dentistry. You might wish to say what you are aiming to be doing in 5

and 10 years time.

Managing completion of clinical training

Please use this section to describe how you will manage the completion of your

clinical training alongside your academic development. Please provide a

timetable of your plans.

Support from Host Department

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Please explain how the host department offering the Clinical Lectureship you

have chosen will support your research aims and career objectives.

Any further information

Please use this section to provide information which might support your

application that has not been covered elsewhere on the form. Please describe

the skills and attributes that you feel you have which make you a suitable

candidate for a Clinical Lectureship.

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http://www.ucl.ac.uk/ioo/jobs/full7265-7.htm

Clinical Research Associates in Vision Research(MRCOphth or equivalent required)

The National Institute for Health Research (NIHR) Specialist Biomedical Research Centre (BMRC)for Ophthalmology at Moorfields Eye Hospital NHS Foundation Trust / UCL Institute ofOphthalmology is seeking to accelerate the application of clinical and basic research in thetreatment of blinding eye diseases. We have vacancies for three motivated individuals who haveachieved MRCOphth or equivalent residency training recognised by the GMC to join us as ClinicalResearch Associates within the research themes of Diabetes, Ocular Surface Disease orPaediatric/Inherited Eye Diseases.

Applicants must have achieved the MRCOphth or equivalent overseas qualification; be able toperform a competent clinical ophthalmological examination; be committed to high quality researchand be able to perform technically and intellectually demanding experiments independently.Previous research experience is desirable, as is a BSc (or overseas equivalent) qualification.

The Clinical Research Associates will have considerable input into research project direction; workcollaboratively with colleagues; organise project data; present research at national andinternational meetings; prepare project results for publication; undertake specific technical/clinicalduties relevant to individual projects.

Appointment is likely to be made at the base of the appropriate clinical research scale, either CL7(29,580-37,510) or CL8 (37,510-42,813) plus London Allowance at 2,649. The post-holderswill be based at UCL Institute of Ophthalmology and Moorfields Eye Hospital NHS Foundation Trust.Recruitment will be made for 24 to 36 months, in the first instance. Please see individual job

descriptions for specific terms.Please click for:

Job description for Inherited Eye Disease

Job description for Ocular Surface Disease

Job description for Diabetic Retinopathy

and an application form or via email at : [email protected]. Please quotereference number: 127265-7.

Completed applications should be returned by post (as signed copies are required) to thePersonnel Office, UCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL,U.K. In the interests of economy only those candidates who are called for interview will

be notified of the outcome of their application. Any applicant who is not an EU or UKresident, should be aware when applying that any offer will be dependent on theInstitute being able to obtain a valid work permit on his/her behalf.'

Closing date for the receipt of applications: 25 July 2008.

UCL Taking Action for EqualityPursuing Excellence in Education and Research

UCL INSTITUTE OF OPHTHALMOLOGY

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Ocular Surface Diseases

Clinical Research Associate

REF: 127266

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UNIVERSITY COLLEGE LONDON (UCL)

INTRODUCTION

UCL is one of the UKs premier universities. It is a world-class research andteaching institution based in Londonwhose staff and former students have included19 Nobel Prize winners. Founded in 1826, it was the only university in Englandatthat time which admitted students regardless of race or religion. UCL was also thefirst to admit women on equal terms with men. Today UCL is a friendly university inwhich to work and study and it continues to thrive on the diversity and creativity of itscommunity.

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UCL is in practice a university in its own right, although constitutionally a collegewithin the federal University of London. With an annual turnover exceeding 485million, it is financially and managerially independent of the University of London.

The UCL community

UCL has over 18,000 students from over 140 countries and employs over 8,000 staff,

including 3,800 plus academic staff. In total, there are 70 Academic Departments and

Institutes whose activities span the following: arts and humanities, social and historical

sciences, law, architecture and the built environment, engineering, mathematical and

physical sciences, life and clinical sciences, and medicine. UCLs academic and research

staff are a truly international community with more than a quarter coming from 84 countries

outside the UK.

UCLs annual turnover exceeded 485m in the latest financial year. Over 12,000undergraduates and 7,000 graduate students study at UCL, of whom over 25%come from 130 countries outside the UK. UCL offers 275 undergraduateprogrammes and more than 220 taught postgraduate programmes as well as theopportunity to carry out postgraduate research in all of its subjects.

UCL has the highest number of professors of any university in the UK, an academic

community including 35 Fellows of the Royal Society, 27 Fellows of the British Academy, 13

Fellows of the Royal Academy of Engineering and 75 Fellows of the Academy of Medical

Sciences. Nobel Prizes have been awarded to 18 academic staff and graduates.

Quality of UCLs teaching and research

Two measures of the current quality of UCLs teaching and research are the resultsof the external teaching quality assessment reviews and the periodic ResearchAssessment Exercise (RAE).

During the teaching quality reviews conducted in the period 1993-2001, 75% of allreviews of UCL Departments resulted in ratings of excellent (22+ points out of 24).Of these, four Departments received the maximum 24 points.

In the 2001 RAE, 60 UCL Departments achieved top ratings of 5* and 5: of these, 15Departments have since been classified by the Higher Education Funding Council forEngland (HEFCE) as 'best 5*' for HEFCE research funding purposes - that is,departments which either received the 5* rating both in 2001 and in the previousRAE in 1996 or which improved their 1996 rating to 5* in 2001 while maintaining orincreasing numbers of research active staff. These 'best 5*' departments span thefull range of UCLs disciplines.

Another measure of UCLs research excellence has been its success in bidding forexternal competitive funds from the Joint Infrastructure Fund (JIF) and the ScienceResearch Investment Fund (SRIF). With the addition of required matching funds, JIF

and SRIF are allowing UCL to invest more than 250 million into state-of-the-artinfrastructure for cutting-edge research and teaching programmes.

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UCL is consistently rated among the top four universities in the UK (together withCambridge, Imperial College and Oxford) and in the 20 best universities in the world.

UCL Institute of Ophthalmology

The Institute of Ophthalmology is one of a number of specialised biomedicalresearch centres within UCL and is, together with Moorfields Eye Hospital, worldsleading centres for eye health, vision research and training.

UCL Institute of Ophthalmology conducts cutting-edge science, attracting research workers

of the highest international calibre. In recognition of our international standing, the Higher

Education Funding Council for England (HEFCE) has awarded us the highest possible rating

in the last three Research Assessment Exercises; we hold a "5**".

The researcher of tomorrow is critical to our goal of improving sight. To this end, we are

involved in graduate training of research students (MD, MPhil, PhD) and our contributions to

UCL undergraduate and taught graduate teaching are increasing year by year.

The Institute is committed to a multi-disciplinary research portfolio thatfurthers an understanding of the eye and visual system linked with clinicalinvestigations targeted to specific problems in the prevention and treatment ofeye disease. The combination of the Institutes research resource with theresources of Moorfields Eye Hospital, which has the largest ophthalmic patient

population in the Western World, opens the way for advances at the forefrontof vision research and provides an unparalleled setting for research andtraining in ophthalmology.

IT facilities are available to all staff and the Institute has modern, well-equipped laboratories which cater for academic staff whose specialities fallwithin the remit of four Research Departments:

Cell Biology

Genetics

Ocular Biology and Therapeutics

Visual Neuroscience

The Institute employs 170 staff, has a budget of 11m and is locate next to the City of

Londons main financial district near Old Street Underground station, a short distance from

Liverpool Street Rail station.

To find out more about our research and teaching visit http://www.ucl.ac.uk/ioo/

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Background

The National Institute for Health Researchs Biomedical Research Centre forOphthalmology is based at MoorfieldsEye Hospital NHS Foundation Trust and theUCL Institute of Ophthalmology. Established in April 2007, the Centre is funded bythe Department of Health via the National Institute for Health Research. Theobjective of the Centre is to conduct 'translational research' that is designed to takeadvances in basic medical research from the laboratory to the clinic, enablingpatients to benefit more quickly from new scientific breakthroughs. The research ofthe Centre falls within five major research themes: Age-related MacularDegeneration, Diabetes, Glaucoma, Ocular Surface Disease, PaediatricOphthalmology and Inherited Eye Disease.

Our centre is one of 11 Biomedical Research Centres in the UK that were awarded to NHS-

university partnerships having an outstanding international reputation for medical research

and expertise, and experience of translating research into the clinical setting. For further

information, please see www.moorfields.nhs.uk/bmrc

Moorfields Eye Hospital NHS Foundation Trust

MoorfieldsEye Hospital NHS Foundation Trust is a teaching hospital managed by a Trust

Board appointed by the Secretary of State. The Hospital is closely associated with the

adjacent UCL Institute of Ophthalmology and this association fosters a unique mixture of

teaching and research.

The Hospital has a 24-Hour Accident and Emergency Department, modern and well

equipped Operating Theatres, an extensive Outpatient Department and a wide range ofclinical and non-clinical support services. Moorfieldsalso has eleven Community Eye

Service Units which provide community based Primary Ophthalmic Care and Specialist

Services. Patients are referred from the surrounding catchment area, but additionally both

the Hospital and Institute provide a nationwide service for consultation and treatment of rare

or complex cases. The Hospital has an Ophthalmology training programme for SpRs/ OSTs

who are based within the North Thames Ophthalmology Rotation. For further information,

please see www.moorfields.nhs.uk

The Ocular Surface Diseases Research Theme: The objective of this research theme is toreduce the impact of disorders of the cornea and conjunctiva in patients and the population.

We have prioritised the following two areas of translational research within the Ocular

Surface Diseases theme and the successful applicant will work on one of these projects.

The post-holder is encouraged to consider enrolling for a higher degree (eg. PhD). Training

in all techniques will be given.

Limbal Stem Cell Transplantation project

Limbal epithelial stem cell (LESC) failure, resulting from injury or disease, results in

significant patient discomfort and loss of vision. The Cells for Sight Transplantation Unit wasestablished in 2002 to translate laboratory research into successful treatment for LESC

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failure and is based at the Institute of Ophthalmology, directed by Dr.Julie Daniels and

Mr.Stephen Tuft.

The research programme is centred on improving outcomes in the LESC therapy currently

undertaken on patients in Moorfields and developing novel cell-based therapies to treatocular surface disease (see Stem Cells 2007;25:1402 and Surv Ophthalmol2007;52:483). It

includes the following projects,

(i) Identification of novel localised stem cell-rich areas within the limbus which will facilitate

targeting of biopsies for optimal autologous LESC expansion in culture.

(ii) Identify alternative sources of mucous membrane suitable for ocular surface

reconstruction using autologous tissue.

(iii) Attempts to control the LESC phenotype by manipulating gene expression in stem cells.

The long-term goal is to develop gene-based approaches for LESC failure.

Corneal Transplantation projectOne of the major problems in corneal disease are patients who require corneal

transplantation to restore vision, but in whom the likelihood of successful surgery is very

poor. Over the next 3-5 years, the research programme on corneal transplantation will have

a dual approach of prevention of corneal transplant rejection by the host immune system

and augmentation of transplant endothelial function post-grafting by ex vivo genetic

modification of donor cornea pre-graft. The research will be undertaken at the Department of

Molecular Genetics, Institute of Ophthalmology and Moorfields Lions Eye Bank, directed by

Professor Robin Ali and Mr Frank Larkin.

The research will build on earlier pilot studies of cDNA transfer to donor corneas to induce

endothelial cell replication and prevent allogeneic rejection (Invest Ophthalmol Vis Sci

2005;46:3597 and Eur J Immunol2006;36:690). Further investigation is required to bring this

approach to the stage that it can be translated into clinical transplantation and we plan to

investigate the efficacy and safety of new technologies (Nature Med2006;12:348) for gene

transfer. The expertise in vector development in the laboratory of Professor Ali will be

essential in developing this aspect of the project.

The recently constructed Moorfields Lions Eye Bank will be a platform to allow evaluation of

these interventions and, as for the Cells for Sight facility described above, provide proven

new interventions to improve transplant outcomes in patients.

The Post

For either project, the post-holder will be required to,

have considerable input into project direction and experimental design

work collaboratively with other members of the team and clinical colleagues

organise project data

participate in laboratory meetings and journal clubs

achieve goals, agreed in discussions with the principal investigators, independentlyand efficiently

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present the results of the project in national and international meetings

prepare the results of the project for publication

perform any other duties within the scope, spirit and purpose of the post, the title of

the post and its grading as requested by the supervisor and head of division.

the post-holder will gain experience in the clinical management of patients with ocular

surface diseases.

Person Specification

Knowledge including Qualifications

Medical qualifications: MBBS, MRCOphth

Skills

Must be able to perform basic ophthalmic examination competently.

Good basic IT skills.

Experience

Should have experience of working in a multi-disciplinary environment and a multi-

disciplinary team working.

Should ideally have some experience of previous clinical or laboratory research.

Personal Qualities

Commitment to high quality research.

Ability to work collaboratively and as part of a team.

Commitment to maintaining a good knowledge of the published literature in

the relevant fields. Have an agreeable manner.

Commitment to UCLs policy of equal opportunity and the ability to work

harmoniously with colleagues and students of all cultures and backgrounds.

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4. Person Specification

Requirements Criteria

E / D*

Assesse

dA / I*

1. Education, Qualifications and Training

MRCOphth or equivalent overseas Ophthalmology

qualification

E A

BSc or equivalent overseas qualification D A

2. Skills, AbilityAbility to perform a competent clinical ophthalmological

examinationE A / I

Good IT and computer skills E A / I

3. Experience

General ophthalmology E A / I

Previous research experience in a clinical or laboratory

environment

D A / I

Experience of working in a multi-disciplinary environment E A / I

4. Knowledge

5. Personal qualitiesCommitment to high quality research. E I

Ability to work collaboratively and as part of a team. E

Ability to perform technically and intellectually demanding

experiments independently

E I

Commitment to maintaining a good knowledge of the

published literature in the relevant fields

E I

He/she will be required to have an agreeable manner E I

Commitment to UCLs policy of equal opportunity and the

ability to work harmoniously with colleagues and students of

all cultures and backgrounds

E I

* E = Essential; D = Desirable; A = Application; I = Interview

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5. Conditions of Appointment

Appointment

The post is graded as CL7 or CL8. CL7 starts at 29,580 and ends at 37,510 plusdiscretionary points and CL8 starts at 37,510 plus and ends at 42,813 plus discretionarypoints. London Allowance is currently 2,649 and is paid in addition to basic salary.Although consideration will be given to a candidates skills, experience and knowledge,appointment will normally be made at the base of this range. Cost of living pay awards arenegotiated nationally and are normally effective from 1st August each year.

To be considered for CL8,in addition to the above criteria, the candidate would beexpected to have research experience with evidence of achievement (such as publishedresearch papers) in a subject area relevant to the post. In addition, the candidate would beexpected to demonstrate potential in some or all of the following areas:-

leading a small team of researchers

being invited to give papers at conferences

serving on peer review Committee.

Duration

The post will be offered for 36 months, in the first instance.

Location

Employees of the Institute normally work at the Institute's main location in 11 - 43 Bath

Street, London EC1V 9EL. Some members of staff may also be located within Moorfields

Eye Hospital, City Road, London EC1V 2PD. The Institute reserves the right to re-locate

staff between the above two organisations. Occasionally, staff may be required to work at

other locations; this will be subject to discussion between the member of staff and the

Institute.

Probation

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Appointments are subject to receipt of satisfactory references and a probationary period of 9months.

Hours of Work

Full time hours are 36 hours per week and times of work are as determined by the InstituteDirector, normally between 8:00 am and 6.00pm Monday to Friday.

Holidays

Annual leave is 27 working days for a full time member of staff.

UCL also closes for a period at Christmas and Easter, at which times staff benefit from atotal of 6 closure days in addition to Bank Holidays.

Pension

If the post holder is not already a member of the NHS pension scheme he/she will beeligible to join the Universities Superannuation Scheme, which is a final salaryscheme with a current employee contribution rate of 6.35% and an employercontribution rate of 14% of salary.

Season Ticket Loans

A season ticket loan is available to staff who have successfully completed their probationaryperiod with the facility to repay through a monthly deduction from salary.

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Equal Opportunities

Our policy includes the provision that in recruitment, the only consideration must be that theindividual meets or is likely to meet the genuine requirements of the job. No one will be

discriminated against on the basis of gender, age, race, colour, ethnic origin, physical

disability, marital status, sexual orientation, caring or parental responsibilities, or belief in any

matters including religion and politics.

Informal Enquiries

Informal discussion with the BMRC Administration or appropriate Theme Leader (Mr Frank

Larkin) or associate consultant specialist (Mr Stephen Tuft) can be arranged through Ms

Louise Halfhide at [email protected] phone 020 7253 3411,

extension 4657.

For further information about the UCL Institute of Ophthalmology, please visit our website at

http://www.ucl.ac.uk/ioo/

Details of how to apply for the post

Applications should be either:

1. CV plus the Application for Employment form found athttp://www.ucl.ac.uk/hr/docs/download_forms/recruitment_selection_I.doc and the Equal Opportunities Classification form; or

2. UCL Standard Application Form found at:http://www.ucl.ac.uk/hr/docs/download_forms/job_app.doc

Applications must be accompanied by a supporting letter which should include:

Job reference 127266

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Whether we may approach one or all of yourreferees prior to interview.

Please note that we require details of at least two referees (to includeyour current/most recent employer) together with their full postal address,telephone number and email details. Relatives may not be used asreferees.

Whether you require permission / a work permit to take up employment

in the UK.

If employed, how many days (and how many periods) of sick leave you

have had over the last 12 months (provide additional information if you

feel this would be useful).

Applications should be sent to the address below. All applications must be received before

17:00hrs on the closing date. Please send 4 copies of your documentation to:

The Personnel Officer

UCL Institute for Ophthalmology

Fax: +44 (0) 20 7915 1039

Closing date for applications is 25 July 2008.

Closing date for applications: Monday 25th July 2008

We particularly welcome female applicants andthose from an ethnic minority, as they are under-represented within UCL at these levels. This is inline with section 48 of the Sex Discrimination Actand section 38 of the Race Relations Act.

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Unfortunately we cannot write to applicants who are not shortlisted. Consequently, if you

have not heard from the Institute of Ophthalmology within four weeks of the closing date,

please assume that you have not been shortlisted. We hope that this does not discourage

you from making further applications in the future.