Inside of cell Interior of rough endoplasmic reticulum 5' Receptor protein Signal recognit ion particle mRNA Ribosome Signal sequence Protein synthesis begins on free ribosomes. Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
Inside of cell Interior of rough endoplasmic reticulum 5' Receptor protein Signal recognition particle mRNA Ribosome Signal sequence Protein synthesis.
Dec 21, 2015
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Inside of cell
Interior of roughendoplasmic reticulum
5'
Receptor protein
Signal recognition particle
mRNA
Ribosome
Signal sequence
Protein synthesis begins on free ribosomes.
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
The polypeptide binds to a signal recognition particle, and both bind to a receptor protein.
Inside of cell
Interior of rough ER
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
The signal recognition particle is released, the signal sequence passes through a channel.
Enzyme for removal of signal
Inside of cell
Interior of rough ER
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
The signal sequence is removed inside the ER.
Inside of cell
Interior of rough ER
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
Excised signal
The polypeptide continues to elongate.
Inside of cell
Interior of rough ER
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
Translation terminates.
Inside of cell
Interior of rough ER
3'
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
Ribosome released
Completed protein
The completed protein moves completely into the ER and the ribosome is released.
Inside of cell
Interior of rough ER
3'
Figure 12.15 A Signal Sequence Moves a Polypeptide into the ER
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