Innovation and Societal Impact How you can get more out of your research, and how CTTC can help
What is Innovation?
• Development, refinement and new application of technology
• Conversion of knowledge and ideas into valuable better business, products and services
• Evolutionary process of increasing the capability to apply a technology
What is Innovation?
To be a true innovation, a product, service or company must have three elements: • it has to be unique, • it has to bring real value to the customer, and • it has to be commercially viable.
INNOVATION CYCLE
Research
Innovation
Research
Patents / Licenses
Products, Services, Jobs
Royalties ($)
idea
CTTC
IMPACT CYCLES
Royalties ($)
Research
Innovation
Patents / Licenses
Products, Services, Jobs
Funding ($)
Research
Discovery
Publication
Grant application
IMPACT CYCLES
Royalties ($)
Innovation
Patents / Licenses
Products, Services, Jobs
Funding ($)
Discovery
Publication
Grant application
Research
IMPACT CYCLES
Funding ($)
Research
Publication
Grant application
Royalties ($)
Research
P
S
INNOVATIONCYCLE
RESEARCH CYCLE
Patenting and Publishing
“Patenting has a positive effect on the rate of publications”
– Azoulay, P., W. Ding and T. Stuart, 2009, “The Impact of Academic Patenting on the Rate, Quality, and Direction of (Public) Research”, The Journal of Industrial Economics, 57(4), 637‐676.
Patenting and Publishing
Academic inventors “publish more and better quality papers than their non‐patenting colleagues”
– Breschi, S., F. Lissoni and F. Montobbio, 2008, “University patenting and scientific productivity. A quantitative study of Italian academic inventors”, European Management Review 5, 91‐110
Patenting and Publishing
“Inventors publish significantly more than their colleagues who work in similar fields and who have similar career characteristics.”
– Van Looy B., K. Debackere and J. Callaert, 2006, “Publication and Patent Behaviour of Academic Researchers: Conflicting, Reinforcing or Merely Co‐existing”, Research Policy 35, 596‐608.
Patenting and Publishing
“…if applied effort leads to publishable output as well as licenses, then research output and the stock of knowledge are higher with licensing than without.”
– Thursby, M., J. Thursbay, and S. Mukherjee, 2007, “Are there Real Effects of Licensing on Academic Research? A Life Cycle View”, Journal of Economic Behavior & Organization 63(4), 577‐598.
Role of CTTC
Serve the Vanderbilt community by assisting University inventors in bringing their innovations to practical application for the benefit of the public
CTTC’s Function
License inventions to industry
Help launch new Start Up Companies
Business Development / Industry Funding
What Does CTTC Do?
Core Operations• Technology evaluation, protection
and licensing• New venture assistance• Federal Government compliance
(Bayh‐Dole)• Medical Products Support
Services (MPSS), including medical device regulatory affairs advisement (MDRAP)
Other Key Functions• Material Transfer Agreement
processing• Education/training• Industry research contract
support• Committee/board
participation• Strategic consultation for VU
and VUMC
What Does CTTC Do?
Core Operations• Technology evaluation, protection
and licensing• New venture assistance• Federal Government compliance
(Bayh‐Dole)• Medical Products Support
Services (MPSS), including medical device regulatory affairs advisement (MDRAP)
Other Key Functions• Material Transfer Agreement
processing• Education/training• Industry research contract
support• Committee/board
participation• Strategic consultation for VU
and VUMC
What Does CTTC Do?
Core Operations• Technology evaluation, protection
and licensing• New venture assistance• Federal Government compliance
(Bayh‐Dole)• Medical Products Support
Services (MPSS), including medical device regulatory affairs advisement (MDRAP)
Other Key Functions• Material Transfer Agreement
processing• Education/training• Industry research contract
support• Committee/board
participation• Strategic consultation for VU
and VUMC
What Does CTTC Do?
Core Operations• Technology evaluation, protection
and licensing• New venture assistance• Federal Government compliance
(Bayh‐Dole)• Medical Products Support
Services (MPSS), including medical device regulatory affairs advisement (MDRAP)
Other Key Functions• Material Transfer Agreement
processing• Education/training• Industry research contract
support• Committee/board
participation• Strategic consultation for VU
and VUMC
What Does CTTC Do?
Core Operations• Technology evaluation, protection
and licensing• New venture assistance• Federal Government compliance
(Bayh‐Dole)• Medical Products Support
Services (MPSS), including medical device regulatory affairs advisement (MDRAP)
Other Key Functions• Material Transfer Agreement
processing• Education/training• Industry research contract
support• Committee/board
participation• Strategic consultation for VU
and VUMC
Importance of Innovation
Since the public is paying for most of the research, it is important for them to see the benefits of innovations resulting from academic research in their lives.
Innovation improves the quality of life for citizens and patients.
Societal Impact
Saccharin
Vitamin D milk
Insulin
Electron microscope
Streptomycin
Magnetic memory
Gatorade
LCDs
Coumadin
Polio vaccine
Hepatitis B vaccine
Cysplatin
Restasis
MRI scanner
TaxolEmtriva
Allegra
PET/CT scanner
Rocket fuel
Plexiglas
Penicillin
Pap smear
Pacemakers
Remicade
Neupogen
Fluoride toothpaste
Tyvaso
A &S School Inventions
03691215182124
2012 2013 2014 2015 2016
# of Disclosures by Year
# of Disclosures
• Total number of disclosed technologies: 377• Disclosures in the last ten years: 233• Number of active technologies: 150• 44 technologies have been included in licensing transactions
Products on the MarketMolecular Sensing, Inc. –
Back‐scattering InterferometryFemtoMetrix, Inc. –
Harmonic F1x
KIYATEC, Inc. – Rotary micropumps and microvalves
Wrap Up
• There is more than one way for your research to achieve IMPACT
• Innovation in research is a moral imperative – if not you, who?
• CTTC has experience and expertise in helping your innovations achieve societal impact.
(competing?) Objectives
• Revenue Generation• Faculty Service• Regional economic development / job creation
(competing?) Objectives
• Revenue Generation• Faculty Service• Regional economic development / job creation
• Societal benefit
(competing?) Objectives
• Revenue Generation• Faculty Service• Regional economic development / job creation• Societal benefit• Partnership development / cultural enrichment
(competing?) Objectives
• Revenue Generation
• Faculty Service• Regional economic development / job creation• Societal benefit• Partnership development / cultural enrichment
Value‐add mindset• Proof of concept• Incubation• Prototyping• New ventures
Service, Service, Service
Commercialization is ultimate goal, not patents
Creating value for VU can take a variety of forms, not just licensing
• Industry collaborations• Philanthropy • Grant funding• Venture investment
CTTC Operations
Technology Commercialization– Evaluation of new inventions– Protection of new inventions– Marketing of technology to industry
• Alternatively, supporting the creation of new ventures to commercialize technology
– Drafting, negotiating and executing technology license agreements
– Revenue invoicing and distribution– License compliance monitoring
CTTC Operations
Protection of IP further includes:– Selecting of patent counsel– Overseeing the drafting, filing and prosecution of patent applications
– Registering of copyrights– Obtaining assignment and other formal documents necessary for patent protection
CTTC Operations
New Ventures– Assessment of new venture ideas
– Assistance and entrepreneurial support to faculty, staff, students
– Co‐PI on NSF I‐Corps grants and participation on I‐Corps teams
CTTC Operations
Federal Compliance Reporting– Bayh‐Dole Reporting
• Invention reporting• Election of title• Confirmatory license to funding agency• Utilization reporting
– Veterans Administration: all joint IP invention management activities
CTTC Operations
Medical Device Regulatory Affairs program• Promote the success of faculty’s medical device R&D
through FDA regulatory affairs support– Assisting with ensuring compliance with FDA design
control regulations– Assisting with grant writing support vis‐a‐vis regulatory
issues– Advising on medical device FDA product type
categorization– Advising on regulatory pathway strategy– Facilitating interactions with and review by IRB– Providing information, education, training, and review for
all involved in regulatory support of medical device R&D– Assisting in commercialization of medical devices and
industry engagement
CTTC Operations
MTA Management– Process ~1000 MTAs each
year to enable research– Implemented MTAShare
system to streamline MTA processing
CTTC Operations
Education and Training of Vanderbilt community– Presentations and training sessions on fundamentals of IP, recent case law, commercialization process, etc.
– Lectures as part of formal Vanderbilt programs –ASPIRE, IMPACT, others
CTTC Operations
Research Contract Support– Review IP and commercialization‐related terms in SRAs, CTAs and collaboration agreements
– Provide revised language and negotiation support to OCM and SPA
– Track review times to assure minimal delay in executing research agreements
CTTC Operations
Fulfill IP obligations under other grants and contracts
– Invention reporting to sponsors– Track IP obligations and limitations for resultant technologies
– Negotiate licenses with Sponsors exercising their option to access IP
CTTC Operations
• Strategic consultation on collaboration opportunities
• Participation, as requested, on boards of directors of portfolio companies
• Committee service