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Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE
15

Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Jan 18, 2018

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Carol Lyons

INFLUENZA HOSPITALIZATIONS BY AGE
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Page 1: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

InfluenzaPertussisMeningitis B

SPOKANE EPIDEMIOLOGY

UPDATE

Page 2: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

UpdatesINFLUENZA

Page 3: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

0-4 5-10 11-20 21-30 31-40 41-50 51-60 61-70 71-80 >800

20406080

100120140

2014-15 Hospitalizations for Flu in Spokane County

Flu BFlu A

Patient Age

Num

ber

of P

atie

nts

INFLUENZA HOSPITALIZATIONS BY AGE

Page 4: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Sep Oct Nov Dec Jan Feb Mar Apr May Jun0

50

100

150

200

250

2014-15 Flu Hospitalization Epi Curve for Spokane County

Flu BFlu A

Month of Admission

Num

ber

of P

atie

nts

INFLUENZA HOSPITALIZATION EPI CURVE

Page 5: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Sep Oct Nov Dec Jan Feb Mar Apr May Jun July0

50

100

150

200

250

Influenza Hospitalizations for Spokane County

2014-152013-142012-132011-12

Num

ber

of H

ospi

taliz

atio

ns

INFLUENZA HOSPITALIZATION – PAST, PRESENT AND …

Page 6: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Composition of the 2015/16 Flu Vaccine A/California/7/2009 (H1N1)-like virus,

A/Switzerland/9715293/2013 (H3N2)-like virus (new), B/Phuket/3073/2013-like (Yamagata lineage) (new)

Afluria approved by the FDA for intramuscular administration via the Stratis needle-free jet injector, for persons aged 18 through 64 years of age.

Flublok is now indicated for persons aged ≥18 years of age.

Preference for LAIV over IIV is no longer recommended for healthy children aged 2-8 years of age.

CHANGES FOR THE UPCOMING FLU SEASON

Page 7: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Fall 2015PERTUSSIS

Page 8: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

54 cases in Spokane YTD.

WA PERTUSSIS EPIDEMIOLOLGY

Page 9: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

WA DOH is looking at getting data on maternal Tdap utilization

Current recommendation is that women get a Tdap immunization in their third trimester with every pregnancy.

Current pilot is looking at what type of information would be available in the major EMRs used in birthing hospitals in the state. In Spokane we are looking at Valley and Deaconess

Hospitals. Goal is to get maternal Tdap information from all

birthing hospitals in WA.

RESEARCH IN WASHINGTON STATE

Page 10: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Infants who get pertussis from a known source get it from who? 35.5% from siblings 20.6% from mothers 10.0% from fathers 85.2% for total of immediate

and extended familyhttp://www.medscape.com/

viewarticle/850781

EPI PEARL - PERTUSSIS

Page 11: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Different bug but similar disease… Outbreak in Minnesota in Fall of 2014. Key points:

Over 31 cases identified with similar clinical picture as pertussis 40% of the patients had post-tussive vomiting 40% had coryza 32% had apnea or sleep disturbances 12% reported a sore throat Cough persisted for up to 8 weeks And none had fever

Pertussis vaccine is not effective against parapertussis

PCR testing can distinguish between the two http://www.medpagetoday.com/MeetingCoverage/

ICAAC/53655

I.D. POTPOURRI - PARAPERTUSSIS

Page 12: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Fall 2015MENINGOCOCCAL DISEASE

Page 13: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Historically vaccines for meningococcal disease covered 4 of the 5 strains (A, C, W135 and Y) but a vaccine covering the B strain has not been FDA approved for use in the US

Type B is responsible for roughly a third of meningococcal cases in the US and is more common with infants

In 2013-14 a large number of outbreaks of meningitis B were associated with colleges The 2013-14 outbreak at Princeton led to CDC requesting

and receiving approval from the FDA to import Bexsero to respond to the outbreak.

MENINGITIS B

Page 14: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

Two vaccines available for Meningitis B protection. Bexsero is available with 2 doses over 1

month Approved by FDA in January 2015 for ages

10-25 Trumenba is available with 3 doses over 6

months Approved by FDA in October 2014 for ages

10-25

MENINGITIS B VACCINES

Page 15: Influenza Pertussis Meningitis B SPOKANE EPIDEMIOLOGY UPDATE.

QUESTIONS?