Infection of Virus

8/8/2019 Infection of Virus

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General Characteristics of Viruses

I nfectious agents that are too small to be seen with a light microscopeParasites of animals, plants and some bacteria

That are not cellsCan replicateI nfect all cellular lifeMultiply

Only inside a living host cell (obligateintracellular parasites)Contain DN A or R N A but never both.


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Components of Viruses

N ucleic acid core ( DN A or R N A)

Caspid : surrounding protein coat

Envelope : some viruses have thisadditional surrounding lipid

bilayer membrane

Virion : a complete virus particle


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Classfication of Viruses

H istorically, virologists classified viruses by type of host or the host structures they affected:-

Bacterophages: infect bacterial cellsPlant viruses : infect plant cells

Animal virus are subgrouped by the tissues they

attack:i. D ermotropic : if they infect the skinii. N eurotropic : if they infect nerve tissues


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Classfication of Viruses

Classified based on:-i. Type and structure of their nucleic acidsii. Method of replicationiii. H ost rangeiv. Other physical and chemical

characteristics


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Types of Viruses

Papovavirus:eg:- H uman Papilloma Virus ( H PV).

Retrovirus:eg:- H uman I mmunodeficiency Virus

(H I V).H erpesvirus:

eg:- Cytomegalovirus (CMV).- H erpes Simplex Virus ( H SV).

Etc


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P apovavirus.

Eg : H uman Papilloma Virus ( H PV).Types strain infection human

- type 16,18,31,33,35

Causes warts, including genital wartsOccurs in cervix genital tract

- transformation- vagina

- vulvaCell that infected:-- endocervical cell- metaplastic cell- squamous cell


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P apovavirus.

General symptoms :- Warts on the skin (face, hands, legs, feet) may be

itchy or slightly tender,- but are often asymptomatic.


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H uman P apilloma Virus ( HP V).


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H erpesvirus:

Eg: H erpes Simplex Virus ( H SV).Types of strain that infecting human:

- type 1

- type 2 (can caused cancer)occur in cervix genital tract:

- L abia- Clitoris- Vagina- Cervix


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H erpesvirus

General symptoms :- intense itching- burning sensation

- pain


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H erpes Simplex Virus ( H SV)


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Scheme of H SV


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H erpesvirus

eg: Cytomegalovirus (CMV).Occur in:

- endocervical endometrium


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Cytomegalovirus (CMV)


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Scheme of CMV


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Retrovirus

eg: H uman I mmunodeficiency Virus ( H I V)immune system begin to failleading to life-threatening oppurtunistic infection.

types:- H I V 1- H I V 2

transmission:- sexual relationship- blood- multiple infection


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Retrovirus

the clinical course of infection:H I V infection 4 stages

I ncubation period

Acute infectionL atency stage

A ID S


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H uman Immunodeficienc y Virus ( H IV)


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End~~Prepared by:

N uraldayana D aud 3071025381D ip. Tek. Makmal Perubatan

Siti Munirah I smail 3071004821D ip. Tek. Makmal Perubatan

Ros Farhana Rosli 3071025991D ip. Tek. Makmal Perubatan

N urul Ezzati Md Esa 3071025541D ip. Tek. Makmal Perubatan

N urul Aini Abu H assan Sheiri 3071025641D ip. Tek. Makmal Perubatan

Suindah N ordin 3071025881D ip. Tek. Makmal Perubatan

Infection of Virus

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