Congenital malformations Low birth weight Sudden infant death syndrome Maternal complications Unintentional injuries Cord and placental complications Bacterial sepsis of newborn Respiratory distress of newborn Diseases of the circulatory system Neonatal hemorrhage Infant deaths per 100,000 live births 0 20 40 60 80 100 120 140 2015 2016 91 06 845 | 19.04-5 | SL | Subject to modifications | © 2019 Drägerwerk AG & Co. KGaA Factors affecting survival: – low birth weight – early birth resulting from induction or C-section due to a medical condition or oxygen deprivation before the delivery – Steroid treatment given prior to birth in order to speed up lung development The infant mortality rate (IMR) - the ratio of infant deaths to live births in a given year - is generally regarded as a good indicator of the overall health of a population. Helping infants with respiratory distress to breath easier. Seattle PAP plus – Bubble CPAP System is a simple and effective non-invasive solution for respiratory support. About 10% of premature babies in the United States develop RDS each year.⁵ Maternal risk factors for preterm birth include previous preterm birth, periodontal disease, low maternal body mass, poor prenatal care, poverty, being uninsured, and being a member of a minority group.⁵ With approximately 18,000 hospitalizations each year due to RDS, the total cost of treating these babies in the hospital is approximately $2.3 billion.⁵ INFANT MORTALITY RATES BY STATE LEADING CAUSES OF INFANT DEATH SEATTLE PAP PLUS BABYFLOW PLUS Birth asphyxia and Hypoxic-Ischemic Encephalopathy are 2 peripartum events and leading causes of all neonatal deaths worldwide.² PREMATURE BIRTH AND SURVIVAL STATISTICS A system of components engineered for neonates and infants to maximize performance and patient comfort while addressing current issues associated with non-invasive respiratory support therapy. Birth asphyxia causes 23% of neonatal deaths worldwide⁴ HIE is estimated to occur in about 3-20 per 1,000 live births, making it the most common type of infant brain damage⁴ INFANT MORTALITY STATISTICS IN THE UNITED STATES The mortality rate of pre-term babies in the United States is still one of the highest for developed countries accounting for 1 in every 10 babies born. Respiratory Distress Syndrome continues to be one of the most treatable complications and improving outcomes.¹ Deaths per 1,000 live births 0 - 4.8 4.8 - 5.8 5.8 - 6.2 6.3 - 7.3 7.4 - 9.1 0% 25% 50% 75% 100% Length of Pregnancy in Weeks 23 24 25 26 27 28-31 32-33 34+ The 10 leading causes of infant death accounted for 67.5% of all infant deaths in the United States. These two interventions provide non-invasive therapy for neonatal breathing support. Lack of breathing/ Respiratory Distress Syndrome (RDS) 1. https://www.nichd.nih.gov/health/topics/infant-mortality/topicinfo/causes; https://www.cdc.gov/reproductivehealth/maternalinfanthealth/infantmortality.htm 2. United Nations Inter-agency Group for Child Mortality Estimation (UN IGME), ‘Levels & Trends in Child Mortality: Report 2017, Estimates Developed by the UN Inter-agency Group for Child Mortality Estimation’, United Nations Children’s Fund, New York, 2017 3. Research Article: A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports 4. https://hiehelpcenter.org/what-is-hypoxic-ischemic-encephalopathy/hie-facts-statistics/ 5. https://www.thoracic.org/patients/patient-resources/breathing-in-america/resources/chapter-19-respiratory-distress-syndr.pdf Source: https://www.cdc.gov/nchs/pressroom/sosmap/infant_mortality_rates/infant_mortality.htm Source: https://www.verywellfamily.com/premature-birth-and-viability-2371529 Source: https://www.cdc.gov/nchs/data/databriefs/db293.pdf