Incorporating a Pressure Sensor- Transmitter (RF) Complex on Transseptal Cannula for use with TandemHeart™ PTVA System Team Members: Mihoko Hashimoto Lauren Kokai Nitin Narayana Katie O’Callaghan Project Advisors: David H.J. Wang, Ph.D. Douglas E. Smith, Ph.D. Dennis Kopilec Marlin H. Mickle, Ph.D. University of Pittsburgh Senior Design – BioE 1160
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Incorporating a Pressure Sensor-Transmitter (RF) Complex on Transseptal Cannula for use with TandemHeart™ PTVA System Team Members: Mihoko Hashimoto Lauren.
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Incorporating a Pressure Sensor-Transmitter(RF) Complex on Transseptal Cannula for
use with TandemHeart™ PTVA System
Team Members: Mihoko Hashimoto Lauren Kokai
Nitin NarayanaKatie O’Callaghan
Project Advisors: David H.J. Wang, Ph.D. Douglas E. Smith, Ph.D.
Dennis KopilecMarlin H. Mickle, Ph.D.
December 5, 2003
University of PittsburghSenior Design – BioE 1160
Overview
TandemHeartTM - A centrifugal pump that allows for fast deployment of oxygenated blood from the Left Atrium (LA) to the femoral artery and thus bypassing the Left Ventricle (LV).
• Advantages: Reduced workload on LV, possible healing of LV, helps maintain blood circulation and organ perfusion during heart surgery, bridge to transplant.
• Audience: Cardiologists and Cardiac Surgeons (maintaining blood flow), patients suffering from myocardial infarction or acute carditis, patients with deteriorating LV functionality waiting for a transplant, patients recuperating from heart surgery (increase speed of LV healing).
OverviewProblem:
Unmonitored changes in LA pressure (below a certain pressure threshold) may pose a threat to the patient due to a potential “suck down” of tissue (overdrainage of LA). Cause tissue damage and reduce blood flow.
Solution:
Real time pressure readings in the LA can possibly prevent the tissue “suck down”.
• Incorporate a pressure sensor into the tip of the Transseptal Cannula along with the use of RF-technology for signal transmission.
• Effectively determine an appropriate pump speed depending on patient’s conditions without further invasive processes.
Project GoalsThe ultimate goal of this project is to enable real-time
measurements of Left Atrial Pressure (LAP) with TandemHeart use, by placing a barometric absolute pressure (BAP) sensor chip (Kavlico sCAP1) at the tip of the cannula.
+ Incorporation of RF transmitter complex to transmit the real-time measurements without need for wiring.
+ Determine durability of the device after coating using simulated conditions.
High Level Timing Goals
1) Analysis of pressure sensor properties & manufacturing limitations
2) Development of sensor-signal transmitter (RF?) complex
3) Establish that device meets PDS under simulated clinical use conditions
4) Verify accurate signal transmission in intended clinical environment
Future Project Opportunities
Successful completion of this project could be used for future development of a safety pump speed adjust feature in the pump controller.By developing an algorithm to respond to low LAP conditions, the
controller on the TandemHeartTM will be able to auto-adjust (a vital safety feature) by decreasing pump speeds.
The sensor-RF transmitter complex could also be applied for countless other internal biomedical devices!!
Features & Benefits
Pressure sensor
provide potential for accurate real-time monitoring of LAP to prevent “suck down” of LA
allow for more accurate/sensitive pump speed for individual patient’s condition
(less need for highly trained system operator)
RF transmitter
no need for wiring
Group Object Tree
Pressure Sensor on Transseptal Cannula for TandemHeartTM PTVA System
-Determined scope of project and documented specific deliverables CAI requires from students at conclusion of project
*Determined Product Design Specifications
-Communicated project schedule and goals through Gantt chart, Function Means Tree, Object Tree
• Group meeting with U of P advisor Marlin H. Mickle, Ph.D
-Students presented summary of project goals and relevant design information, discussed student needs for assistance and obtained background info on RF technology and circuit integration components, as well as anticipated difficulties
• Order placement for Kavlico sCAP 1 BAP sensor chips (5)
Acknowledgements
CardiacAssist• Drs. Doug Smith & David Wang, Dennis Kopilec
• Project funding
• Provision of pump system supplies & testing equipment