2/14/13 1 More Effective Population Size Concepts Inbreeding effective population size the size of an ideal population with the same probability of randomly sampled alleles being IBD as the real population Variance effective population size the size of an ideal population with the same sampling variance in allele frequency as the real population Inbreeding effective population size observed change in heterozygosity (IBD) over time can be used to estimate N e P IBD ( ) = 1 2 N e N e i = 1 2 P IBD ( ) N e i !" t 2 ln H t / H 0 ( )
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2/14/13
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More Effective Population Size Concepts
v Inbreeding effective population size ² the size of an ideal population with the same
probability of randomly sampled alleles being IBD as the real population
v Variance effective population size ² the size of an ideal population with the same
sampling variance in allele frequency as the real population
Inbreeding effective population size
v observed change in heterozygosity (IBD) over time can be used to estimate Ne
P IBD( ) = 12Ne
Nei =
12P IBD( )
Nei ! "
t2 ln Ht /H0( )
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Variance effective population size
v observed changes in allele frequencies over time can be used to estimate Ne