18 yo \·lm found right qroi n ma ss 8/70 . lliopsy in terpre te d as Lympho- /I!J/ sarcoma . The t umo r v:dS tn:i: t ed 1·1ith local irradi ation and givsn -, chemothe r apy . ·. . . (0 Autoosv ll<tS pe rfo rmed and tumor ll'.:! t astas 1s Ne re fo und 1n 11 ver , l ung , spleen', bone mal'rm ·t , und ly mph nod es . No tumor is prese nt in testes. CASE A 62-70 - ---- ..... _ DX: LYHPH NOOES, BONE NA RR0 \<1 AND .. LIVER - HODGKIN 'S DISEASE, L Y1 1PI'.OCYTE DEPT,E TIO 'N (HODGKIN ' S Or:' JACKZCm AKD PARKER) Kaplan, H, S ., et a l.: Trea tment of Hodg ki n's disease . Clin . N. Amer. , 50: 1591, 1966 Keller, A, R., et al. : C orrelati on of hi stopatho lo gy Hi th othel' progno n tic t or s in Hodgki n ' s se . Canc er , '-2: 487 , 1968 . Glatstein, E., et al .: The va lue of a nd sple nec t omy in the sta - ging of Hodgkin's disease . Canc er , 24 : 70 9, 1969 , St rum, S, n., et a'r. .: Ob servat ion of c ells 1·escmbling Sternberg-Reed cells in c· ouditions o· ther than Hodgkin !s disease . Cance r, 26: 176, 1970. ' : cd.Jl . ... / .- - . t. · ro , r-ktt.U.o lx +- · <oH • : .... yl..f. . .. ....... /.( Yf-'11 •· .... ·, 4 -s <JLo..o • ... :; . ' "'fffr "'f'-M... .V '1 c.- ..;:. . J..<;c.o.., fv 4""'<4 - .. .. ..c,·o..... _ )IS : ("yfrr4.. .;: y-J-r '4u. l4i.p; $p> J'-!1 (q 7. 10o7. ?o P. /O 7. 3-6.?. 4V (. 3t'}, r- N. ..... ..... o '4'"' (.I,) or- '- ..... '4'"'-- {.f 1) "' of .,. - W'-'- lv...... N,., ......... W"'-
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18 yo\·lm found right qroi n mass 8/70 . lliopsy interpreted as Lympho- /I!J/ sarcoma. The t umor v:dS tn:i:t ed 1·1ith local irradi ation and gi vsn -, chemother apy . ·. . . (0 Autoosv ll<tS performed and tumor ll'.:!t astas 1 s Nere found 1 n 11 ver, l ung , spleen', bone mal'rm·t, und lymph nodes . No tumor is present in testes .
CASE A 62-70 - ----....._
DX: LYHPH NOOES, BONE NA RR0\<1 AND .. LIVER - HODGKIN'S DISEASE, LY1 1PI'.OCYTE DEPT,ETIO'N (HODGKIN ' S S:\RCO:·~". Or:' JACKZCm AKD PARKER)
Kaplan, H, S., et a l.: Trea tment of Hodgkin's disease . ~:ed . Clin . N. Amer. , 50: 1591, 1966
Keller, A, R., et al. : Correlation of histopathology Hi t h othel' prognontic in~l~a t ors in Hodgki n ' s disc~ se . Canc er, '-2: 487 , 1968 .
Glatstein, E. , et al .: The va lue of la paro~omy a nd splenec t omy in the staging of Hodgkin's disease . Canc er , 24 : 709, 1969 ,
Strum, S, n., e t a'r. . : Observation of c ells 1·escmbling Sternberg-Reed cells in c·ouditions o·ther than Hodgkin !s disease . Cancer, 26: 176, 1970.
20 yowm. Routine chest x~ray sho\'led mediast i na l mass . At operati on l arge 10 by 10 by H) ems . ante!' i or f;tectiast·!ltal mass !,:vadi ;;g LL l obe of 1L;r.g . L
Liebo,. , A. A. , e t al : Scleros ing hemt~ ngiomo ( histiocy toma , :<o nthollla ) of t he l ung , Ca ncer, 9 : 53, 1956 .
Ti tus , J. L. , et n l: Xantho..-.atou s and inflamma t or y pseudotumors of the l ung . Ca ncer, 15 : 522, 1962 .
~lentworth , P . , et al : Xantholl'.a tous pseudotumo1· of l ung . A case r eport wi th electron mi c r oscopic and l.ip i d studies . Ca ncer , 22 : 345 , 1968 .
Fos ter , E. A,, et al. : l,ocalized mesothcliomn s of the pl eura . Amct . J , Clio . Pa th . , 34 : 349, 1960 .
-535 64 yo;'lln shcrc~e-Ja rectal m<>ss wh·ich increased ir. si ze in the 1ast yr- . {\surgical in t.e t~venl.i on \'.'a ~ per1Ur 1i~2U 'oi.H~ arht.) , t;.. \..~ lii:i ) Oil.! si g:-;ro i~ col on ;·tere removed . Start·ing at the anus , and extending up into the r-ectum is a 7. 5 ems. mass ~1ith an ulcet·ated surface. Section XIV and XV is colon , XVI- anal areas . XVII-rectal mucosa.
CASE S-535-69
DX: SKIN, AN liS - ANGIOS..>\RCOHA
Stout, A. P .: Uotr,angiocndothelioma : a tumor of blood vessels fca turing vaacular endothelial cells. Ann. Surg . , 118: 44.S, 1.943 .
9-333 76 yom \',•ith a fi rm 1.;f t ~ i,;r~ g .,at.!.') .,. ~!c::c: kn~.:>~ a •1d • .. rL ~ loss \·Je te · i iHpressi ve . Surgical speci nwr~s came from 1ef-t 1ung and pleur a which 1·/ei' e inf i1hated by t he t umor as v1e 11 as the thoraci c vta 11 . · I Biopsy I I: Pleu;-a, Biopsy I V: f·1al'gitis of t t.mlOi' i n l ung, Biopsy V: Marginsk:J pf tumor in l ung .
CASE S-69-333
OX: LUNG - ~\RCINOSARCO~~ --Ber gmann, H,', et al: Carcinos a rcoma o£ the lung . Ca ncer , 4: 919, 1951.
Stackhous e, E. M. ,. et al: Prima r y mi x ed ma l i gna nc i es of lung : ca·rc i nosarcoma and blastoma . J , Thor. Ca r cliova sc Surg ., 57 : 385, 1969 .
Ratzer, E , R., e t al: Pleural meso theliomas . Ame~ . J . Roen t genol., 99: 863, 1967 .
·70- 33~0 68 ya11m who , l'lhile hammering noted pain in the ri ght ~rm and ~hen . . deve l oped a r ap i dly sv1elli ng (fc· .. 1 days) mass i n the nght ant1cub nal fossa . At surgery the a:·ea gross ly l ooked li ke a hemat a11a .
CASE S-70-3340 ----DX: SOFT TISSUE - MALIGNANT l'IBROUS XI\NTBONA (l'rBROXANTHOSARCO~lA)
Q.'Brien, J . E., e t al: Haligoant fibrous xan t homas . Cancer, 17: 1445 , 1964.
Kempson, R, L. , et al : Atypical fibroxan thoiMs of the skin . Cancer, 17 : 1463 , 1,964 .
Kempson , R, L. , et al : Fibr oxa n thosarcomas of soEt tissue . Cancer (in press)
En zinger , F. H. , et a 1: Liposar coma . A stu,ly of 103 cases . Vircho_.s Arch . Path , Anat . , 335 : 367, 1962 .
-(
·&9- 6652 ·69-5401
2:l yo·,rf vlith 'l re cur rent abdominal pain and ascites for 4 yrs . 111 she has a surgical intervention ~II ell il biuf.~Y di~g~oserJ ;,s"acutc oer·itonitis ~lith mesotheli al pro1iferation" . She had tvro other intervent'ions at Du~c. ->The first one has the biopsy fJ 569- 6,!01; mated a 1 submitt ed vtas : "peritoneal lin~ng of don:c of bladder a11d ovary . One month l a,ter , the ovaries , tubes, and. uterus vrere removed (S- 59-6£52)
Wl.nsl.ow, D. J., et at.: }t•Ugnant Jleritoneal mesothel1'o1• ·"· " " 13·.
127. 1960 . ·~- voncer '
·-70- 1203 46 yom ~lith a stomach ulcel'ation fo r 10 yrs . Partial gastrecto:cy was perfor;ned.
CASI! S- 70-1803 a DX: S!ONACR - SUPERFlCL.I\L REP"nc u~ I Ul ffit I
Efi~UA<... IWRElZPIA~A Ahlb IJI1MPt\Oib "WIP\i:RP!:A'i>LABragg, D. G., ct al : Roentgenologic and p~thologic aspects of superfic i al spreading carcinomo of the stomach . Amer. J, Roentgenol., 101 : 4 37, 1_967 .
Ha son , H . K: : Surface carciooma of the stomach. Gut, 6 : 185 , 1965 .
Perez , C. A., ct al. : Benign lymphoid hyperplasia of the stomach and duodenum. P.adiol. , 87 : 505, 1966.
70-!IBS
CASE S-70-91:!8
DX : HEDIAS1.'IW~·l,'I'H'iHUS- THYJ.:Ol·:A (;dth m:;astt'nia grav i s) ---........._
/0
Lattes , R.: '111yr .. oma and other tumors of the thymus . Cancer , 15 : 1224, 1962.
Hil!tins, J , ll, H. 1 e t a 1. : Cctses of thyl)loma at t he l·1•ssachusctts General Hospita l. J. Thor . Cardiova sc . Surg . , 52 : 32 2, 1966 .
Fechner, R. E.: Recurrence of noninvas ive thymomas . C~ncer, 23: Il>23, 1.969 .
Go l dstein , G., e t al. : The 'human thymus. l?arren U. Green , St . Louis , 1969 .
i10-8981
_C. .. SJL s_-70-898 t
!>X : LUNG - F!Bl\OXAN'rHOMA (Itl~'LAHt·lA 'IOnY PSEUllOTUHOR, SCL!':ROSING HENANGIOMA ) .. References same a s for Case S-70-3340
The patient has a mitral stenosi s c cal'C!iac f ail ure . 2 yrs. ago a cerv i cal bi opsy was diagnosed as intraepithelial carcinoma . In the middle of a recent ~lorK:UP a coin type lesion 11as found in the r i ght lung (inter l obar fiss ure . )
~ ('\
I J
"5u1U,~ gNIIto t.C6 y ~· ( 1-.J'/lr((_
~ u. '>O!iOcx.. of ~CA.LJ£. , ~. o~ ~~t..0~Y k/OV. 2.0 , f<{. 'l 0
CASE ,6 , ~2 79 (:., l)O-,[J-3- l !-J oT 1r\SOJI:¥e'ts)
OX: LYHPH NODES, BONE HARROH AND LIVER - HODGIUN' S DlSE:AS!l, LYMPHOCYTE DEPLETION (HODGKL"'' S SARCO:-'.A OF JACKSON Al<~D PARKER)
Kaplan, Ji , S. , et al.: Treatmen t of Hodgkin's di sease . Hed . Clin. N. Amer . , 50 : 1591, 1966
· Kelle>: , A. R., et al. : Con:elBtion of his topathol ogy 11ith other prognostic . in1i~~tors i n Hodgkin's disease. Cancer, 22 : 487 , 1968 .
Glal:stein , E., et al.: l'he va lue of laparotomy and splenectomy in t he sta ging of Hodgkin ' s disease . C.........u.,
Str um, s. Jl. , et al.: Obs erva tion of cells r ea embl i ng Sternberg-Reed cells .in conditions other than Hodgkin ~ s di se.1se. Cancer, 26 : 176, 1970 .
Obe r man, II. A., et al.: ·~w l ignant germina l t umors of the med i astinulll. Canc er , 17:498, 1964 .
Tei1um, G, : Enclodcrmal s i nus tumors of the ova ry and testis . Cancer, 12 : 1092, 1959 .
Hunt ington , R,. H. J r ., e t a l: Yolk sse tumors of cxtragcnacla J. origin. Cn nce1:, 25 : 1368, 1970 .
~IDr :I. Jl·Padilla, N,: Origi11 , natu1·e a nd s :tgnificllnce of thE! "elt.bryol.ds " of hullt9 n tera toma s . Vi rc hotJs Arch . Pa th. Ana t • , 340 : 1C'5, 1 9',5 .
0 CASE S-67-1132
DX: SOFT TISSUJ> - GP-ANUU1R CELL 'rUMORS, THREE
' Thoren, 1 . : On tl>e mJM!re end patr.ogenesis oi ~he so-catll.'d Abrikoso£f tumour. Acta Soc . }fE!d. llpps., 55 :125,1950 .
Strong, E. W., et a1 : Granula r cell myoblas::oms. Canc"r , 25 : 415, 1970 .
Ga ranc is , J. C. , e t al : Granular cell tlyoblastoma . C:lncer, 25 : 542 , 1970 .
Liebo_. , A. A., e t al: Scl eros i ng hemangioma (hl s tiocyto:na, xanthoma ) of the l ung . Ca ncer, 9: 53, 1956 .
Ti.tus, J. L,, e t a 1: Xanthoma rous and inf.la!llll!oc1 to ry pseudo tumors of tho lung . Cancer , 15: 522 , 1962 .
l~ent,4orth , P., e t al : Xonthom,1tous pseudotumor of lung . A case report with e lectron mic roscopic end lipid studi es . Qlncer , 22 : 345 , 1968 .
~·oster, i:: , A., e t al. : Local ized mesotheliomas of t he pleur a . Amer. J. Clin . Pa t h . , 34 : 34 9 , 1960 .
CASE S-535-69
OX : SKIN , Al\'US - ANGIOsARCOMA '
Stout, A . P.: Hcmangioendo the liome : a t umor of hl ood vessels f:ca turi ng vasc ul ar endothelial cells . Ann . Surg . , 118 : 445 , 1943 ,
Bergma,n , 11., el al : Corcinosarco~ of the lu!l&. Qlnccr, 4 : 919, 1951.
Sta ckhouse , E . ~1. , e t a ]: Pr:i.mnt·y mixed ma li&nbnc ies of lung : carcinoar.J:coma and blastoma . J . Thor . Cardiovasc Sur g ., 57: 385, 1969.
Rotzer, E. R. , el a 1 : Pleural m,Go tl;-llomas . At.er . J. F.o.:>entg"nol. , 99. 863 , 1967 .
~linsloH , D. J., et al : l'.alignant perit:o114<1l mcsotheliow.as . Cancer, 13 : 127, 1960 .
CASE S-70-1803
DX: S'l\'li'1ACJ1 - SUPERFIC I AL Pl!l?'l'IC ULCTlll, l~I'rll RP.GENEHA'CXON ATYPIA OF TU E! EPITHELIUM AND LYMPHOID HYPERPLASIA
Bragg, D. G., et ~tl : Rocnt genologgc and pathologic a spt:c ts of superficial sprcoding carcinoma of t he .stomach. A mer. J. 1\oentgenol . , 101 : t,:n , 1967 .
Hason , :;!. K.: Surface carcinor•:t of the stom3ch . Gut , 6: 185, 1965 . ~ ~ ..
Perez, c. A. , et al : lle11ign lymphoid l1ypr~rplosi.n of tho stomach and duodenum. Radiol., 87: 505, 1966 .