High clinical value EliA TM Supplier 1 Supplier 2 Sensitivity 97.7 % 96.7 % 99.2 % Specificity 89.8 % 89.8 % 76.3 % Positive predictive value (PPV) 0.96 0.96 0.90 Negative predictive value (NPV) 0.95 0.93 0.98 EliA TM Calprotectin is a very sensitive and specific test for fecal calprotectin to differentiate inflammatory bowel diseases (IBD) e.g. Crohn‘s disease, ulcerative colitis, from irritable bowel syndrome (IBS) and other functional bowel disorders (BD). High sensitivity, high specificity and excellent predictive values for EliA TM Calprotectin assure high clinical value in different clinical settings. Fecal calprotectin is effective as a first line test for discriminating IBD from IBS, after diagnosis for monitoring disease activity, and during clinical remission for a prediction of relapse. 1 In terms of discrimination it clearly outperforms blood tests such as CRP or ESR. 2 Figure 1: Performance of EliA TM Calprotectin in 191 stool samples (132 IBD, 59 IBS, and other functional bowel disorders). Cut-off for positivity: 50 mg/kg (internal study) Differentiate IBD / IBS clearly Provide early diagnostic guidance Test completely automated, and efficiently Routine stool extraction samples are processed automatically by the Phadia ® Laboratory Systems (Phadia ® 100 / 250 / 2500 / 5000) thereby reducing the workload for your lab personnel. Operational costs are minimized and planning simplified – leading to an optimized workflow! Table 1: Performance data of EliA TM Calprotectin and tests from two other suppliers (internal study) EliA TM Calprotectin 1000 100 10 1 mg/kg IBD IBS and other functional BD cut-off Identify inflammatory bowel diseases CALPROTECTIN
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High clinical value EliATM Supplier 1 Supplier 2Sensitivity 97.7 % 96.7 % 99.2 %Specifi city 89.8 % 89.8 % 76.3 %Positive predictive value (PPV) 0.96 0.96 0.90Negative predictive value (NPV) 0.95 0.93 0.98
EliATM Calprotectin is a very sensitive and specifi c test for fecal calprotectin to differentiate infl ammatory bowel diseases (IBD) e.g. Crohn‘s disease, ulcerative colitis, from irritable bowel syndrome (IBS) and other functional bowel disorders (BD).
High sensitivity, high specifi city and excellent predictive values for EliATM Calprotectin assure high clinical value in different clinical settings. Fecal calprotectin is effective as a fi rst line test for discriminating IBD from IBS, after diagnosis for monitoring disease activity, and during clinical remission for a prediction of relapse.1 In terms of discrimination it clearly outperforms blood tests such as CRP or ESR.2
Figure 1: Performance of EliATM Calprotectin in 191 stool samples (132 IBD, 59 IBS, and other functional bowel disorders). Cut-off for positivity: 50 mg/kg (internal study)
Differentiate IBD / IBS clearly
Provide early diagnostic guidance
Test completely automated, and effi cientlyRoutine stool extraction samples are processed automatically by the Phadia® Laboratory Systems (Phadia® 100 / 250 / 2500 / 5000) thereby reducing the workload for your lab personnel. Operational costs are minimized and planning simplifi ed – leading to an optimized workfl ow!
Table 1: Performance data of EliATM Calprotectin and tests from two other suppliers (internal study)
EliATM Calprotectin
1000
100
10
1mg/kg IBD IBS and other
functional BD
cut-off
Identify infl ammatory bowel diseases
CALPROTECTIN
Your advantages with EliATM Calprotectin:• clear differentiation between IBD and IBS• early diagnostic guidance• completely automated and efficient testing • reduces the workload for your lab personnel• add-on to the EliA
TM
gastro panel on Phadia®
Laboratory Systems
EliATM Calprotectin helps you improve service quality: fully automated testing for a specific and sensitive intestinal inflammation marker providing excellent first line diagnostics of bowel diseases.
References: 1 Sutherland AD et al (2008). Review of fecal biomarkers in inflammatory bowel disease. Dis Colon Rectum 51:1283-1291 2 Tibble J et al (2000). A simple method for assessing intestinal inflammation in Crohn‘s disease. Gut 47: 506-513
EliATM CalprotectinImproved lab analysis and diagnostics
EliATM Calprotectin offers a complete solution: from stool extraction to automated sample measurement.
Dilution 1:100Cut-off / measuring range negative positive measuring range ≤ 50 mg/kg > 50 mg/kg 15 – ≥ 3000 mg/kg
Ordering information Package size Article No. EliATM Calprotectin Well 4 x 12 wells 14-5610-01
For more details, ask for the EliATM Calprotectin product information brochure.