I/C Graft Chamber - LifeNet Health · I/C Graft Chamber ® I/C Graft Chamber is a proprietary mix of Demineralized Bone Material and cancellous chips designed to maintain osteoinductive
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
I/C Graft Chamber is a proprietary mix of Demineralized Bone Material and cancellous chips designed to maintain osteoinductive potential and osteoconductive properties.
Allows surgeons to customize hydration options to fit patients’ needs by using the following options:
68-40-09
0 RE
V.00
When combined with bone marrow aspirate, the I/C Graft Chamber provides the three necessary mechanisms for bone formation:
Osteoconductivity
Osteoinductive Potential
Osteogenicity
• bone marrow aspirate (bma)• Platelet Rich Plasma (PRP)
• Whole Blood• Saline
The natural porous structure of cancellous chips provides
an optimal scaffold for cellular attachment
and vascular in-growth.
Comprised of 100% natural bone matrix which is
remodeled naturally during the bone healing process.
hIGh Dbm CONteNt Available in three volumes to accommodate a variety of clinical indications.
The graft is sterilized using proprietary and patented Allowash XG® technology, providing a sterility assurance level of 10-6, without compromising the graft’s inherent osteoconductivity or osteoinductive potential.
1. Soltan M, Smiler D, Choi JH. Bone Marrow: Orchestrated Cells, Cytokines, and Growth Factors for Bone Regeneration. Implant Dent. 2009 Apr;18(2):132-41.2. Sampath T.K., DeSimone D.P., Reddi A.H. Extracellular bone matrix-derived growth factor. Experimental Cell Research. Volume 142, Issue 2, December 1982, Pages 460-464.3. Baylink MS. Bone growth factors. Clin Orthop Relat Res. 1991 Feb;(263):30-48.4. Solheim E. Growth factors in bone. Int Orthop. 1998; 22(6):410-6.5. Balink DJ, Finkelman RD, Mohan s. Growth factors to stimulate bone formation. J Bone Miner Res. 1993 Dec;8 Suppl 2:S565-72.6. Hannink G, Piek E, Hendriks JM, Van der Krann PM, Schreurs BW, Buma P. Biological effects of rinsing morselised bone grafts before and after impaction. Int Orthop. 2009 Jun;33(3):861-6. Epub 2008 Jan 16.7. Honsawek S, Powers RM, Wolfinbarger L. Extractable bone morphogenic protein and correlation with induced new bone formation in an in vivo assay in the athymic mouse model. Cel and Tissue Banking (2005) 6:13-23.8. Ganski, L, Linthurst J, Moore MA, Malmstrom D, Holy CE, Volence FJ, Bruder SP. Comparative Evaluation of the Osteoinductive Potential of Commercially Available Demineralized Bone Matrices in an Athymic Rat Posterolateral Spinal Fusion Model. Poster No. 1451 53rd Annual Meeting of the Orthopedic Research Society.
The cortical particulate (DBM) is demineralized using LifeNet Health’s patented and proprietary PAD process. This process carefully exposes natural growth factors including BMP-2, BMP-4, BMP-7, and TGF-B 1 trapped within cortical bone.1.-8.
I/C Graft Chamber bONe marrOw aSPIratION NeeDle Contains 1 – Bone Marrow
Aspiration Needle, 2 – 10cc Syringes
bONe marrOw aSPIratION KItS Contains 1 – Bone Marrow Aspiration Needle,
6 – 20cc Syringes, 1 – Specimen Cup. Note: Two needle kit options are available: Single-hole