I) Testosterone: main androgen (male sex hormone) A) Intro to Testosterone: -produced in response to luteinizing hormone (LH) from anterior pituitary gland -steroid hormone produced by interstitial cells in testes 1) meat more tender 2) lack of sex drive 3) lowered aggression (particularly sexual aggression) ***Human castration: 17 th -18 th C many boys had testes removed to halt puberty and retain soprano voices “Castrati” -effects of lack of testosterone documented in livestock animals that have been castrated (testes removed) 2 - male hormones/ female system May 7, 2012 5:08 PM Reprod Page 1
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I) Testosterone: main androgen (male sex hormone)
A) Intro to Testosterone:
-produced in response to luteinizing hormone (LH)
from anterior pituitary gland
-steroid hormone produced by interstitial cells in
testes
1) meat more tender
2) lack of sex drive
3) lowered aggression (particularly sexual
aggression)
***Human castration: 17th-18th C many boys had
testes removed to halt puberty and retain soprano
voices “Castrati”
-effects of lack of testosterone documented in
livestock animals that have been castrated (testes
removed)
2 - male hormones/ female systemMay 7, 2012 5:08 PM
Reprod Page 1
B) Functions of Testosterone
1) stimulates spermatogenesis (in seminiferous tubules)
-facial & body hair
2) stimulates development of secondary sexual
characteristics: signals of sexual maturity
-enlargement & lengthening of larynx
-increased production in body oils & pheromones
-increased musculature: both skeletal & smooth (ie,
CASTRATO,
BBC
Documentary
Part 1 of 6
CASTRATO,
BBC
Documentary
Part 2 of 6
Reprod Page 2
-increased musculature: both skeletal & smooth (ie,
male dermis = 40% thicker than female)
-change in bone structure & proportion
3) maturation of penis & testes during puberty
(primary sexual characteristics: gamete production &
delivery)
4) behavioral effects: sex drive
5) increased
muscular
development:
anabolic steroids are
testosterone-like
drugs
C) Regulation of Testosterone Production
-at ~age 10, hypothalamus matures & releases
gonadotropin releasing hormone (GnRH) which targets
anterior pituitary (this occurs in both males & females)