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Feb 23, 2022

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environmental or healthcare..waste management.!

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Andreas Voss

Radboud UMC & CWZ

Nijmegen

The Netherlands

http://www.slideshare.net/iPrevent

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Robert Weinstein estimated that the source of pathogens causing a healthcare-associatedinfection in the intensive care unit was as follows:

patients’ endogenous flora, 40%–60%;

incl. antibiotic-driven changes in flora;

cross infection via the hands of personnel, 20%–40%;

other (incl. environment): 20%.

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modified from Wenzel and Edmond

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MR

SA

ESBL

C.d

if&

Co

CR

E

…..

PREVENT everything

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Adapted from Otter et al ICHE july 2011, vol. 32, no. 7

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Innate surfacesWater

AirHCWs & patients

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Coming here

Hematology Operatingroom

Airborneisolation

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Brandt et al, Ann Surg 2008; 248:695-700.

63 surgical departments participating in KISS

>99.000 operations

Turbulent + HEPA versus laminar airflow + HEPA

Multivariate analyis to comtrol for other factors influencingoutcome (SSI)

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Brandt et al, Ann Surg 2008; 248:695-700.

Follow-up study taking in account the size of the LAF plenum shows no difference in outcome

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Mycobacteria & endoscope

reprocessing

Legionella and aerosols

Nonfermenters (especially Pseudo-

monas & Acinetobacter) in sinks &

ventilators

Molds in hematology units

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Villegas et al ICHE 2003;24:284-95

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Thus, what is allthe fuzz about?

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Weber et al. Am J Infect Control 2010;38:S25-33

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Kramer et al. BMC Infect Dis 2006;6:130

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Kramer et al. BMC Infect Dis 2006;6:130

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Kramer et al. BMC Infect Dis 2006;6:130

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C. difficile , VRE, MRSA 103 to 109 CFUs/g in stoolNorovirus 1012 particles/g

Environment is generally <10 organisms per cm2

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The infectious dose for most environmentally

associated nosocomial pathogens appears to

be low.

Less than 15 S. aureus cells were sufficient to

cause infection in experimental lesions,

Less than 1 CFU/cm2 was sufficient to cause

C. difficile disease in mice

A single norovirus particle is thought to have the

capacity to cause infection

Otter et al ICHE july 2011, vol. 32, no. 7

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Contact with hospital room surfaces or medical

equipment by healthcare personnel frequently

leads to contamination of hands and/or gloves.

Weber & ICHE may 2013, vol. 34, no. 5

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Stiefel et al ICHE 2011:32:185-87

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Bobulsky et al. CID 2008;46:447-50

Skin (orange), gloves (blue)

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Bonten et al. Lancet 1996;348:1615-19

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Improved environmental cleaning has led to

reduced risk of VRE and C. difficile transmission.

Admission to a room previously occupied by a

patient with MRSA, VRE, Acinetobacter, or C.

difficile increases the risk for the subsequent

patient admitted to the room to acquire the

pathogen

Weber & ICHE may 2013, vol. 34, no. 5

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Otter et al. AJIC 2013;41:56

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Huslage et al. Infect Control Hosp Epidemiol 2010; 31(8):850-853

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Huslage et al. Infect Control Hosp Epidemiol 2010; 31(8):850-853

Obviously all should be clean,but high-touch really needs to be!

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Eckstein et al. BMC Infect Dis June 2007

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Eckstein et al. BMC Infect Dis June 2007

C. difficile

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Eckstein et al. BMC Infect Dis June 2007

VRE

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Boyce et al. ICHE 2008;29:723

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Copper a day -Keeps MRSA away

Noyce et al. J Hosp Infect 2006;63:289-297

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Thom et al. Infect Control Hosp Epidemiol 2014;35:1060-62

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Thom et al. Infect Control Hosp Epidemiol 2014;35:1060-62

MSDS Poly spray (silicone quaternary amine)

8 surfaces

sink, call button, bedside table, monitor,

telephone, supply cart, door handle, floor

Results:

No significant effect on environmental

contamination

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Thom et al. Infect Control Hosp Epidemiol 2014;35:1060-62

Problem adherence?

Love the concept of changing the surface

Studies with copper, silver silica, Biosafe HM

4100 (polymer) embedded in polyurethane,

light-activated antimicrobials, … have worked

before

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Freeman et al. Antimicrob Resistance Infect Control 2014;3:5

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Freeman et al. Antimicrobial Resistance and Infection Control 2014, 3:5

Rooms of patients with ESBL-KP have substantially highercontamination rates than those with ESBL-EC. This finding mayhelp explain the apparently higher transmissibility of ESBL-KP in the hospital setting

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Kampf et al. BMC Infect Dis 2014;14:37

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Kampf et al. BMC Infect Dis 2014;14:37

Reusable tissue dispensers with different surface

disinfectants were randomly collected from

healthcare facilities.

66 dispensers containing disinfectant solutions

with surface-active ingredients were collected in

15 healthcare facilities. 28 dispensers from nine

healthcare facilities were contaminated

In none of the hospitals dispenser processing had

been adequately performed

… it is not about the details of this paper, but the point that even

“helpful parts of the environment” may be a source for infections

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Roomservice

Roomservice-plus

Registered nurse

Nurse asistant

Cleaning

Even if you think youknow it, are theyactually doing it?

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Weber et al. J Hosp Infect 2012;80:252-4

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Highest rate of mannequin contamination was long sleeves + tie (transmission occurred in 4/5 experiments) and lowest withshort sleeves no tie (0/5).

> >

Weber et al. J Hosp Infect 2012;80:252-4

Eli: “flaw in this study was that ties were narrowly defined as neckties and excluded bow ties”

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http://haicontroversies.blogspot.nl

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Enter a solution to all of our infection control

problems: the Jumbo Squirting Bow Tie!

This often overlooked clothing accessory is a veritable

infection prevention dream.

A bow tie can increase our professionalism and limit

pathogen transmission.

Add in the "Jumbo Squirting" action and you can squirt

alcohol hand rub into the eyes of non-compliant clinicians

(operant conditioning) and also into your own hands to

improve compliance with the WHO 5 Moments.

http://haicontroversies.blogspot.nl

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https://www.surveymonkey.com/r/2XG8LV6

iPrevent