Hyperbilirubinemia in the Newborn

The differential diagnosis for persistent jaundice during the 1st mo of life: • cholestasis, • hepatitis • , cytomegalic inclusion disease, syphilis, toxoplasmosis, • familial non-hemolytic icterus, • congenital atresia of the bile ducts, • galactosemia, or • inspissated bile syndrome following hemolytic disease of the newborn . • Rarely, physiologic jaundice may be prolonged for several wk, as in infants with hypothyroidism or pyloric stenosis .