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uman organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1 , A.K. Krylov 2 , Y.V. Gurov 1 , S.S. Zaguskina 1 uthern Federal University, Institute of physics, Rostov-on-Don, Rus [email protected], +79185144967 2 The establishment of the Russian Academy of Sciences, Institute of psychology of RAS, Moscow, Russia, [email protected]
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Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Mar 30, 2015

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Page 1: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Human organism adaptation strategies to geomagnetic storms

S. l. Zaguskin1, A.K. Krylov2, Y.V. Gurov1, S.S. Zaguskina1

1 Southern Federal University, Institute of physics, Rostov-on-Don, Russia,[email protected], +79185144967

2 The establishment of the Russian Academy of Sciences, Institute of psychology of RAS, Moscow, Russia, [email protected]

Page 2: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Galactic radiation Solar activity Moon

Magnetosphere, ozonosfera, atmosphere, hydrosphere, lithosphere

PHYSICO-CHEMICAL EFFECTS ON THE BIOSPHERE

Sol-gel transitions

ManBody tissue Cell

Society

Biological connection, memory, traces processes

Biorhythms: genetically anchored, homeostatic, exogenous

Page 3: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

RHYTHMS OF SOLL-GEL TRANSITIONS IN A CELL AS ACCEPTORS AND RECEPTORS OF OUTSIDE IMPACTS

Gel

SolСаi

Primary/initialacceptors

Receptors of cell membrane CN

Н2О

1О2

Pm МP

Са depot

Function

Biosynthesis

Blood flow

t°C, рН, Роsм

Physical impacts

Chemicalimpacts

Energyexchange of a

cell

Direct functional links,

Feed back links, Energetic links

?

Page 4: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Interferometry of Stellar cluster «Snowflake» and differential interferometry of living neuron. Registration of rhythms sol-gel structures

?

Page 5: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Isolated neuron temporary connection output after increasing its energy metabolism

• 1- Neuron's activity during the action of laser exposure (dashed mark) and mechanical stimuli (solid mark)

• 2- combined impact• 3- responses on the

electric irritation and trace oscillations after elimination of the mechanical effects

• 4-neuron activation responses under electrical impact

1

2

3

4

Page 6: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Circahoral (20 min-2h)

5-min

1 - min

30 sec.1-5s. (pulse, breath )7-13 Hz tremor,α-rhythm of brain100 Hz-10kHz

Biological rhythms Cosmic and geophysical rhythms B.M. Vladimirsky, 1980

It is likely that many of our problems .. are caused by contradiction between our internal time and the and the magnitude of external time in the world around us. I. Prigogine 1984

Page 7: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Evolutionary integration levels of biosystems

Main levels:Biosphere, Biocenoses,

Organisms, Cells, BSRC-biosynthetical self

reduplicating cycles of sol-gel structures

Biosphere

Physical-Space Level (above Biosphere)

Biocenoses

Organisms

Cells

BSRC

genes, viruses

Physical-Chemical Level (pre-biological)

CCH

CCD

Families,flock

FSDO

Ansambles

FSO

FSHB

FSDB

HMC

DMC

ТISSUES

ORGANS

Populations

Consortii

BIOMES

ZONES

m1

l1k1

w1

v1 u1y1

z1

x2

x1

u0 v0 w0

p1

r0

s0

r0

r1

s1

p2 r2

r3

r4

s4

s2

s3

z2

z3

z4

x3

x4

x5

y4

y3

y2

p5?

p4

p3

u3

u4

u2

u5

k2

k3

k4

k5?

l2

l3

l4

m2

m3

m4

v4

v3

v2

w2

w3

w4

z0

Intermediate Functional Levels: FSDB-functional systems of different types of biocenoses,FSHB-functional systems of

homogenous types of biocenoses, FSO – functional systems of

organism, CCD – cell compart-ments of different types, CCH -

homogenous cell compartments .

Intermediate Structural Levels: DMC-cell microstructures of

different types, HМC –homogenous cell

microstructures.

Energy flows upon: x,y,z-functional & p,r,s-structural changes,u,v.w – parametrical regulation of function,k,l,m – parametrical regulation of structure.

Page 8: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,
Page 9: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Universal energy criterion of biological processes direction

adaptation status disadaptation status

1 adaptation strategy ( ΔUN+1<0) : Energy costs for external functional XN+1

and structural PN+1 processes are reduced less compared to internal regulatory ZN+SN processes. 2 adaptation strategy (ΔUN+1 >0): Energy costs for external functional XN+1

and structural PN+1 processes is increasing more than on internal regulatory ZN+SN processes.

Page 10: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Energetic dependence of neuron irritability, and plastic fixation of its adaptation

А Neuron activity pulse frequency records at irritation with the period of 5 minutes.Process of quick decrease of irritability since the beginning of irritation, and quick trigger recovery of irritability after 90 minutes is clearly seen.

B Living ultraviolet cyto-spectre-photometry of neuron. Absorption oscillations with wave length equal to 265 nm at different points of neuron’s body.Primary increase of absorption (increase of РНПconcentration) at points above nucleus as well as step-by-step phase synchronization of absorption oscillations at other parts of a cell following towards neuraxon are clearly seen.

А

B

Page 11: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

2 hour a maximum during ischemia

a maximum during ischemia

1 hour a maximum during ischemia

Increased periods and amplitude of rhythms of R-R intervals redundancy ( R=1−Eexp/Emax) per 1, 2 hour and a maximum during ischemia

pulse

breathing

Page 12: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Analysis of ECG R-R records with symbolic dynamic approach. Groups of people: young healthy (Y, black dots), eldery healthy (E gray dots),

long-term atrial fibrillation (L, blue dots) and congestive heart failure (C red dots)

Page 13: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

с –scope of 44 patients with congestive heart

failure,l –is the area of 84 patients with atrial

fibrillation,y – scope of 10 young

healthy people,e – area of 54 older

healthy people.k1 – a patient number 1,k2 – a patient number 2.

Symbolic dynamics of R-R intervals

k2k1

Page 14: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Nerve cell of mechanical receptor of river crab. Registration of electrical activity, oxygen consumption, mitochondria aggregation,

biosynthesis of protein and ofother structural and chemical rhythms

70 мкм Camera upon microscope desk

З- fixers

З

З

З

рО2

electrode

ganglionbody of neuron

muscles

axon

nerve

Page 15: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Increase of rhythms’ amplitude of sol-gel transitions under laser irradiation and stimulation

of energy potential of a cell

А-microfilm densitography method

В- mitochondria aggregations С- increase of amplitude of mitochondria aggreg.-

disaggreg.- oscillations (optical density 1-2), and sol level related to gel (liquid-faction of cytoplasm) while cell energetic has been stimulated with the help of natrium succinate (or laser)

С

А Вsond

1

2

ВA

Page 16: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Interferometry of living neuron with complete doubling of image. Registration of rhythms of protein content (dry weight) of non-disturbed cell and during physical

impacts

Photoelectrical method:Ф0-Ф1=А{cos2φ-Lcos2(φ-Δ/2)}+M

Photographic method:(S0-S1)/γ=lg{cos2φ/Lcos2(φ-Δ/2)}-M

Page 17: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Synchronous oscillations of energetic exchange and biosynthesis in a cell

About circahoral rhythms (average period is about 30 min) of

protein at different zones of a cell: Д – between dendrites & nucleus, Я –at nucleus zone,А – between nucleus and neuraxon hill for absorption at 265 nm. Tuning:Оptical density - 0,1,Time - 30 мin.

Neuraxon Neuroaxon

Nucleus

Living interferometry of the same neuron at the phase of about one hour rhythm of protein content’s decrease (left) and at the phase of its increase (right). Change of shift of light wave phase above neuron body’s nucleus is clearly seen at the level of two nucleolus, and there are no changes at the part of coming down neuraxon.

А

Я

Д

Д

Я

Page 18: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Criteria of optimum of laser therapy parameters

Harmonic fixed frequency of laser impact

Biorhythm of energy supply Sign of (+) reaction (--)

Parameters are optimal during biocontrol mode only.Factor analysis of Ес, Т, S, λ values is not correct because response reactions are non-additive. Bio resonance ispossible only if multifrequencybiorhythmically biosynchronization is achieved.

Does law of Bunzen-Rosko work?

Effect of laser’s impact 0,3 дж/см2 = Ес мВ/см2 х Тмин

Criteria of optimum of laser therapy parameters

0,5 х10 1х5 5х1 Transition of part of gel into solum

None + ++

СОД activity + + none Level of microcirculation none ++ + Produce of Т-lymphocytes none ++ + PF/BF normalization ++ + none Fractal standard of PF ++ + none

Page 19: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Dependence of +/- responding reaction upon starting state and phase of rhythm of energetics of cell, tissue,

organ, organism

YangYin

Following

Towards

Phаse of decrease of blood congestion

= destruction

Phase of increase of blood congestion

= increase of biosynthesis

Energy supply swing

Page 20: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Ratio оf 1-2-3 depths of amplitude modulation of physio-therapy impact changes depending upon mode of pathology (hypoxia, arterial or venous hyperemia) and upon availability of disbalance of arterial and venous parts of capillary route

1.Тremor 7-13Hz

2. Pulse

3. Breathing

Total signal (1,2,3)of biocontrol

systole

diastole

breath in

breath out

Page 21: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

«RIKTA-05» is the device for bio-controlled lasermagnet chronotherapy

• Chronodiagnostic and patient’s status control during chronotherapy session with bio control using pulse frequency (PF) to breathing frequency(BF) ratio.

• Normal: 3<PF/BF <5.• Modes 1-4: different ratios of

modulation depths due to pulse, breathing, tremor signals.

• Accounting for velocity of pulse wave and place of pathology, delay for pulse signal is introduced.

• During impact upon myocardium projection reverse of pulse signal’s sign is switched on.

Pulses sensor

Breath sensor

Display:PF, BF, PF/BF,Bio-timer,modes 1-4

Теrminal:8 red,1 IR laser,magnet

Page 22: Human organism adaptation strategies to geomagnetic storms S. l. Zaguskin 1, A.K. Krylov 2, Y.V. Gurov 1, S.S. Zaguskina 1 1 Southern Federal University,

Summary1.Developed software and hardware-based medical diagnostic device «Kvant-bio». It contains a pulse, breathing and differential signal input block, thermometry of these sensors in the computer and display the signals on biofeedback matrix laser diodes with power via an adapter from the network. Сhronodiagnostic of human organism state and forecasting its adverse reactions to geomagnetic storms and weather anomalies by using special algorithms for symvolic dynamics of rhythms pulse, breathing and their relationships. Explores the rhythms of vegetation status, of cellular immunity, thermal gradients and thermal asymmetry. To resolve these desynchronosis and their prevention is used in the computer version of the respiratory gymnastics and biocontrol on respiration and pulse sensors with laser therapy. 2. Chronodiagnostic methods allow you to detect when a disagreement of biorhythms within the organism and with the rhythms of the external environment, the forecast adverse reaction of the organism to the geomagnetic storms and weather anomalies.

3. Biocontrolled chronophysiotherapy eliminates desynchronosis, resolves to normalize vegetative status, cell-mediated immunity, the spectrum of blood microcirculation rhythms in the pathology and prevention of adverse reactions of the human body for geomagnetic storms and weather anomalies.