with Ari Whitten How to Overcome Fatigue and Maximize Your Energy Levels Mastering Your Mindset
with
Ari Whitten
How to Overcome Fatigue and Maximize Your Energy Levels
MasteringYourMindset
Whythefocusonenergylevels?
“Energyandpersistenceconquerallthings.”
–BenjaminFranklin
"Ifyoudon'thaveenergy,you'regonnahavenopassioninyourrelaGonship...Ifyoudon'thaveanyenergy,youcan'tdoagreatjobwithyourkidsbecausetheyhavemoreenergythanyoudo.Ifyoudon'thaveenergy,you'renotgoingtorunyourownbusiness,muchlessmulGplebusinesses.
Energyislife.”
--TonyRobbins
Energy is the Crux of a Good Life
Energy levels are the FOUNDATION for your overall experience in life. Your mood, your vitality, your health, your body, your job, your relationships, and your happiness are all intimately tied to energy levels.
• The 2 key principles of energy enhancement
• The most essential strategies you need to DOUBLE or TRIPLE your energy levels.
Here’s What You’ll Learn During This Presentation
• The 2 key principles of energy enhancement
• The most essential strategies you need to overcome fatigue and DOUBLE or TRIPLE your energy levels.
Here’s What You’ll Learn During This Presentation
Why This Is Important To You NOW
If your energy levels are low, EVERYTHING in your life suffers. This presentation will show you how to fix it!
Is This For You?• If you’re someone who is chronically fatigued and lacking
energy and want to understand how to fix it, this is for you.
Is This For You?
• If you’re worried that the diet you’re on and all the supplements you’re taking aren’t helping you, then this is for you because you’re going to discover what type of diet and supplements can help fix your energy and what kind are just a waste of time and money. (Or be making you even WORSE! By the way, that’s much more common than you think).
Is This For You?
• If you’re a health conscious person who is already eating healthy and exercising, this is for you. And I promise you will learn at least a dozen new strategies to boost your energy levels even higher!
• If you’ve got chronic fatigue syndrome or fibromyalgia or adrenal fatigue and you want to finally SOLVE it and get your life back, this is for you.
Is This For You?
• Evenifyouarealreadyhealthyandyoujustwanttobefilledtothebrimeverydaywithtonsofenergysoyou’rereadytoconquertheworldandbringyourbestselfintoallyourrelaGonships,thisisforyou.
Is This For You?
TheEnergyBlueprint
• Inthispresenta1on,Iamgoingtounveilsomethingcalled“TheEnergyBlueprint.”
• Itisaspecificsetoffactorsthatcompletelycontrolshowyourcellsproduceenergy.
• Thisenergyblueprintcontrolsnearly100%ofyourbody’sphysicalenergylevels.
Andonceyouunderstandexactlywhatthesefactorsare…howtheyworktogethertoamplifyyourcellularenergyproducGon…andhowtoimplementtheminyourlife…
Itcanliterallydoubleortripleyourbody’senergylevelswithinamaEer
ofweeks.
Andonceyouunderstandexactlywhatthesefactorsare…howtheyworktogethertoamplifyyourcellularenergyproducGon…andhowtoimplementtheminyourlife…
Itcanliterallydoubleortripleyourbody’senergylevelswithinamaEer
ofweeks.
House Rules• No “magic bullets” “do nothing, get results.” Many people are looking for
some magical fairy dust where you pop some pill once a day and it fixes all your energy issues, this is not the place for it. These are real science-based strategies, and will require you to change certain habits or certain aspects of your environment.
• No half-a$$ing it. If you are not ready to actually make changes in your life and you are content to continue having poor energy levels and relying on caffeine to get through the day, then this is not for you. Hopefully you have your act together and you’re ready to make change and get serious results.
• No “I knew that.” Often times we blind ourselves by assuming we already know something or we’ve already seen it before. Don’t do that. I promise that no matter how well read you are on the subject of health, there are TONS of things in The Energy Blueprint system that you have no idea about. Guaranteed.
• Most people who buy ANY “how to lose weight or increase energy” product will not end up improving their health or quality of life. Lots of people who buy treadmills don’t lose weight, because it ends up becoming a clothes hanger instead of actually being used. So hopefully you’re in the group that’s actually committed to getting results. Because I want you to use the strategies I’m going to give you to dramatically enhance your life.
SoforthoseofyouwhoaresGllwithme…
Here’sbigproblem#1whenitcomesto
energylevels…
WhyICreatedThisProgram
1. Lackofenergyisamodernepidemicofmassivepropor1ons.IntheU.S.,overhalfthepopulaGonstruggleswithdayGmesleepiness,lackofenergy,andfaGgue.DiseaseslikechronicfaGguesyndromeandfibromyalgiaareskyrockeGng.AndalmostEVERYONEwouldlovetoimprovetheirvitality,moodandenergylevels.
2. Almostnoonehasanycluehowtodoanythingaboutit!Themainresponseisjustonenewwackydieta[eranother,andthenewdietaryscapegoatdujour—fat,carbs,sugar,etc.OrjustpseudoscienGficnonsense—superfoods,“detoxes,”etc.ButnorealscienGficsoluGontoenergylevels.
Over half the population struggles with daytime sleepiness, fatigue, and lack of
energy!!
Diseases like chronic fatigue syndrome and fibromyalgia are skyrocketing. ! And almost
EVERYONE would love to improve their vitality, mood and
energy levels.!
• Today,wehaveamassiveepidemicoffa1gueandexhaus1on.
• AndthatisaHUGEproblem,becauseenergylevelsareattheCOREofhavingagreatlife!
Peopleare1red.They’resick.They’restressed.They’reexhausted.They’reanxiousanddepressed.They’reemo1onallyflat—boredandlackingpassion.Andjusttryingtodragthemselvesthroughanotherdaywithcaffeine.
Andit’swreckingpeople’slives.
Herearesomescarystatstothinkabout…
• InWebMD'sannualYearinHealthsurvey,womenacrosstheU.S.namedfa1gueamongtheirtopfivehealthconcerns.
• IntheAmericanPsychologicalAssociaGon's2012StressinAmericasurvey,45PERCENTofwomenreportedfeelingchronicallyfa1guedduetostress.
• AsurveycommissionedbyLegal&Generalfoundthat34percentofthe5,000peopleaskedsaidthatchroniclow-level,generalfa1guewastheirBIGGESThealthconcern.
• TheCharteredManagementInsGtuterecentlyconducteda'QualityofWorkingLife'reportwhichshowedthatinsomniaiswidespreadandmorethanHALFofusexperiencefeelingsofconstant1rednessatwork.
Simplyput…chronicfa1gue,day1mesleepiness,stress,anxiety,
depression,exhaus1on,andchroniclackofenergyhavebecomeEPIDEMICSinoursociety!
That’sthefirstbigproblem…
Here’stheevenBIGGERPROBLEM…
WhyICreatedThisProgram
1. Lackofenergyisamodernepidemicofmassivepropor1ons.IntheU.S.,overhalfthepopulaGonstruggleswithdayGmesleepiness,lackofenergy,andfaGgue.DiseaseslikechronicfaGguesyndromeandfibromyalgiaareskyrockeGng.AndalmostEVERYONEwouldlovetoimprovetheirvitality,moodandenergylevels.
2. Almostnoonehasanycluehowtodoanythingaboutit!Themainresponseisjustonenewwackydieta[eranother,andthenewdietaryscapegoatdujour—fat,carbs,sugar,etc.OrjustpseudoscienGficnonsense—superfoods,“detoxes,”etc.ButnorealscienGficsoluGontoenergylevels.
Here’stheGOODNEWS…
Here’stheGOODNEWS…
YouhavemassivelyabundantenergyAVAILABLEtoyou.Alevelofvitalityandenergynotjust10or20%higherthanwhatyouhavenow,butMASSIVELYhigher.Youcanaccessalevelofenergythatwillfillyouwithdrive,mo1va1on,vitality,andpassioneverysingleday!
• Weallwanttohaveenoughgasinthetanktofollowourdreams,wewanttofeelagency(likewehaveacontrolandmasteryoverourenvironmentandlikewehavewhatittakestoMAKETHINGSHAPPENinourlives),wewanttofeelpowerful…wewanttofeelPASSION…
• …andtheCHALLENGE,thebigobstaclethatgetsinthewayofuslivingthelifewewanttolive…isthatwearedeficientandlackinginthisthingcalledENERGY!
AllofthestuffthatyourbodyneedstodotoFUNCTIONandofcourse,TOTHRIVE…
COMESFROMTHEENERGYBEINGPRODUCEDINYOURCELLS.
Energyandvitalityiswhatallowsustonotonlycopewithallthethingslifethrowsatus,buttothriveinthefaceofitall…topursueourgoalsandmakethemareality…andtoinjectpassionandALIVENESSineverythingwedoinlife.
Toputthisverysimply…
PeoplewhohaveBETTERENERGYLIVEBETTERLIVES!
Energyisthecruxoflivingagoodlife.
SoIwantyoutoSTOPandthinkaboutsomethingforamoment…
SoIwantyoutoSTOPandthinkaboutsomethingforamoment…
WhatwouldyourlifelooklikeifyouhadDOUBLEthephysical
energyyouhavenow?
WHENITCOMESTOENERGY,THEREARE2WAYSOFBEINGINTHEWORLD
WHENITCOMESTOENERGY,THEREARE2WAYSOFBEINGINTHEWORLD
1. DRAGGERS:First,youhavetheNORM.YouhavethemajorityofpeoplesufferingfromchroniclackofenergyanddayGmesleepiness.Relyingoncaffeinetogetthroughtheday,wakingupgroggyandpressingthesnoozebunon,notbeingabletogetgoingwithoutmorningcoffee,needingtosnackthroughoutthedaytokeepenergylevelsup…Tired,overworked,depressed,anxious,stressed,exhaustedandBURNTOUT…draggingthemselvesthrougheachday.
2. PEAKPERFORMERS:ThenyouhavethoseselectfewpeoplewhojustseemtobeBURSTINGwithenergyandlife…alevelofsuperhumanenergy…peoplelikeRichardBranson,OprahWinfrey,andTonyRobbins,They’retheonesthatalwaysseemHAPPY,readytotakeonachallenge,climbtothetopofthemountain,andgetitdonewithasmile.They’retheEnergizerBunnieswhoseemtoaccomplishmoreinthefirstfewhoursofthedaythanmostofuscompleteinaweek.Wesaythingstothemlike,“Wheredoyougetyourenergy?”and“Idon’tknowhowyoudoeverythingyoudo.”
WHENITCOMESTOENERGY,THEREARE2WAYSOFBEINGINTHEWORLD1. DRAGGERS:First,youhavetheNORM.Youhavethemajorityof
peoplesufferingfromchroniclackofenergyanddayGmesleepiness.Relyingoncaffeinetogetthroughtheday,wakingupgroggyandpressingthesnoozebunon,notbeingabletogetgoingwithoutmorningcoffee,needingtosnackthroughoutthedaytokeepenergylevelsup…Tired,overworked,depressed,anxious,stressed,exhaustedandBURNTOUT…draggingthemselvesthrougheachday.
2. PEAKPERFORMERS:ThenyouhavethoseselectfewpeoplewhojustseemtobeBURSTINGwithenergyandlife…alevelofsuperhumanenergy…peoplelikeRichardBranson,OprahWinfrey,andTonyRobbins,They’retheonesthatalwaysseemHAPPY,readytotakeonachallenge,climbtothetopofthemountain,andgetitdonewithasmile.They’retheEnergizerBunnieswhoseemtoaccomplishmoreinthefirstfewhoursofthedaythanmostofuscompleteinaweek.Wesaythingstothemlike,“Wheredoyougetyourenergy?”and“Idon’tknowhowyoudoeverythingyoudo.”
YOUHAVEACHOICE:
Youcanexistineitherofthesetwostates.
ThechoiceisuptoYOU.
LetmetellyoualinlebitaboutmystoryandhowIcametodiscoverTheEnergyBlueprint…
MYSTORYInmyworkoverthelastdecadeasanutriGonist,trainer,andauthor,IhaveseenfaGgueandchroniclackofenergybecomeanepidemic.
IgetdozensofemailsDAILYfrompeoplewhowanthelpovercomingfaGgueandwhowanttoknowhowtoincreasetheirenergylevels.
Myoriginalspecialtywasfatloss,notenergylevels.Foroveradecade,IhaveworkedwithpeopletodramaGcallytransformtheirbodies.Ievenwrotea#1bestsellingbookonthesubjectthatisnowrequiredreadingmaterialinmanydoctors’officesanddieGcians’offices.ButIwasn’talwaysanexpertonenergylevels…whenitcametopeoplestrugglingwithenergylevels,IwouldjusttellpeoplethetypicalstuffeveryonehasalreadyheardamillionGmesbefore(eatright,exercise,lowerstress,drinklotsofwater,get8hoursofsleep,etc.).
SowhenpeoplecametomelookingforadviceonovercomingfaGgueandenhancingenergylevels,Iwantedsomewheretoreferthesepeople.Somegreatproductforenergyenhancementorsomepersonwhowasanexpertonenergylevels…SomeoneIcouldendorse,andwhoIknewwasprovidingacomprehensiveSCIENTIFICapproachtoenergyenhancement.
Sohere’swhatIdid…IspentliterallyMONTHSofreadingvariouspeople’sar1clesonline,watchingvideos,buyingpeople’sproducts,andreadingpeople’sbooksonthesubjectofenergyenhancement…believeitornot,IactuallywentoutandpurchasedliterallyEVERYproductinexistenceonthesubjectofenergylevels—books,seminarrecordings,anddigitalaudioandvideoproducts.IspentliterallyTHOUSANDSofdollarsofmyownmoneyandIspentHUNDREDSofhoursobsessivelystudyingalltheseproducts…
Attheendofallthat—a[erspendingallthatmoneyandallthatGmetolearneverythingfromeveryoneoutthereteachingonthesubjectofenergyenhancement--whatIulGmatelydiscoveredis…
…nooneouttherewasreallyaddressingthefa1gueepidemicwithacomprehensiveSCIENTIFICsystemtoboos0ngtheirenergy
levels!
Almosteverythingoutthereonthesubjectofincreasingenergylevelswaseithercommonsense,orjustabunchofpseudoscien1ficjunk!
SomeoftheseproductshadlinlenuggetsofgoodinformaGon.Butforthemostpart,itwaseither…thesameoldcommonsenseadviceeveryonehasalreadyheardahundredGmes(eatnutriGousfood,doexercise,drinklotsofwater,de-stress,andgetplentyofsleep)or…itwasjustmade-uppseudoscienGficnonsensethathasnobasisinscienceandwon’tworktoenhanceenergylevels.
Evenworse,therewereMANYprogramsgivingadvicethatgoesdirectlyAGAINSTthescienceonthesubject,andifanything,willactuallymakethebodyWEAKERandMOREFATIGUED.
Andthat’swhy…ItookituponmyselftodevelopatrulySCIENTIFICandevidence-basedsystemforop1mizingenergylevels.
Andbytheway,Icertainlycan’ttakeallthecreditbecauseIdidn’tdoitalone…Iwassmartenoughtoreachouttoseveralworld-renownedexpertsinfieldsfromnutriGontocircadianbiology(thebody’sbiologicalclock)tophysiciansonthefrontlinesoftreatchronicfaGguetorenownedneuroscienGsts…AllofwhommadeamazingcontribuGonstothedevelopmentofthesystemIdeveloped.
Now…here’sthething…INEVERimaginedthatitwouldtakewellovertwoYEARSofFULL-TIMEresearchintothescienceofenergylevels,collaboraGonwithseveralotherscienGficexperts,andseeminglyENDLESShoursofexperimentaGonwithHUNDREDSofmyclientstodoit…
ButeventuallyIdevelopedsomethingthatIknewcouldhelptransformthelivesofthousandsof
people…
AspecificformulagroundedinprovenscienGficresearchthatcrackedthecodeforenergyenhancement.
It’scalled
THEENERGYBLUEPRINT
Today,Iamgoingtotellyouaboutthetwofundamentalprinciplesofthat
system.
BeforeItellyouaboutthat…
Let’stalkaboutwhat’soutthererightnowonthesubjectofenergy
levels…
HowMostPeopleAreTryingtoCopewithLowEnergyLevels
“We live in a society where people are always looking for the next
sports drink, energy bar or cup of coffee that will give them the extra
edge to get through the day.”! -- James Levine, MD!
“We have an energy crisis of
historic proportions going
on. We are reaching for
anything that will give us energy—and we’re over-
relying on coffee now more than
ever.” !-- Jacob
Teitelbaum, MD!
• Nowhereonlineinthehealthrealmistheremoreignorance,andlessscienGficunderstandingthanintherealmofENERGY.
• IfyoulooktoarGclesonline,you’llseelotsofarGclesonenergytellingyouto“doexercise”or“eatcarbsinsteadoffat”or“eatfatinsteadofcarbs”or“takeanap”or“drinkcoffee”or“stopdrinkingcoffee”or“eatmoreprotein”or“eatalowproteinrawvegandiet”or“getridofsugar”or“takethisspecialsupplement”etc.
• Notonlyismostofitcontradictory,butit’sreallyjustallthetypicalcommonsensedietandexerciseadviceyou’vealreadyheardathousand1mesbefore.
Here’sWhat’sOutThere…
Sameoldadviceyou’vealreadyheard…
• eathealthynutriGousfoods• doexercise…• loweryourstresslevels…• drinklotsofwater…• takethisherb…• takemyspecialsupplement…• eatyourveggies…• takeyourvitaminsandminerals…• golow-carb…• don’teatsugarorgluten…• cutoutcaffeine…• andsleep8hourseverynight
• OurmaincompeGtorinthisnicheisaguywhoisbasicallyjustpromoGngrawveganism
Here’sWhatElseisOutThere…
• OurmaincompeGtorinthisnicheisaguywhoisbasicallyjustpromoGngrawveganism
• Getridofsugar
• Getridofdairy• Getridofgluten
• Getridofcoffeeandcaffeine• Govegan
• Eat5-6smallmealsthroughouttheday
• Drinkgreenjuices• Doexercise
Here’sWhatElseisOutThere…
• OurmaincompeGtorinthisnicheisaguywhoisbasicallyjustpromoGngrawveganism
• Getridofsugar• Getridofdairy• Getridofgluten• Getridofcoffeeandcaffeine• Govegan• Eat5-6smallmealsthroughouttheday• Drinkgreenjuices• Doexercise
• IfyoulooktoarGclesonline,here’swhatyou’llfind:• Don’tskipmeals(eatbreakfast)• Reducestress• Takeanapeachday• Doexercise• Drinkmorewater• Snackbetweenmeals• Usecaffeine(ordon’t,dependingonwhoyouask)• TakeamulGvitamin
Here’sWhatElseisOutThere…
• OurmaincompeGtorinthisnicheisaguywhoisbasicallyjustpromoGngrawveganism
• Getridofsugar• Getridofdairy• Getridofgluten• Getridofcoffeeandcaffeine• Govegan• Eat5-6smallmealsthroughouttheday• Drinkgreenjuices• Doexercise
• IfyoulooktoarGclesonline,here’swhatyou’llfind:• Don’tskipmeals(eatbreakfast)• Reducestress• Takeanapeachday• Doexercise• Drinkmorewater• Snackbetweenmeals• Usecaffeine(ordon’t,dependingonwhoyouask)• TakeamulGvitamin
If you don’t believe us, look it up for yourself online! !
This is pretty much ALL of the information you’ll find online about boosting energy
levels.!
Here’sWhatElseisOutThere…
ThenYouHaveAlternaGvePracGGonersWhoFocuson“AdrenalFaGgue”…
IfyouregularlynoGceoneormoreofthefollowingsymptoms,you’reverylikelytogetdiagnosedwith“adrenalfaGgue”bythevastmajorityofalternaGvemedicinepracGGoners:
– YoufeelGredfrequentlyandlackenergy.– Youhavetroublegetngupinthemorning,evenwhenyougotobedatareasonablehour.
– Youarefeelingrundownoroverwhelmed.– Youhavedifficultybouncingbackfromstressorillness.– Youhavetroublesleepingthroughthenight.– Youcravesaltyand/orsweetsnacks.
TheSameFactorsthatareClaimedtoCause“AdrenalFaGgue”AlsoCauseRegularFaGgue
OnceYouGettheAdrenalFaGgue
Oncetheydiagnoseyouwith“adrenalfaGgue,”here’sthetreatmentyoucanexpecttogetfromyouralternaGvemedicalpracGGonertocureyouradrenalfaGgue:
• Eliminatesugar,dairy,gluten,caffeine,etc.
• Takeadaptogenicherbs(rhodiolarosea,ashwagandha,ginseng,ginkgo,etc.)• TakelotsofvitaminC
• TakelotsofBvitamins
• Sleep8hourseachnight
• Loweryourstresslevels
• Takeadrenalglandextracts• Takemagnesium
• Eatalowcarbdiet(oreatahighcarbdiet,dependingontheparGculardietarypersuasionofyourchosenalternaGvehealthpracGGoner
• Takeothersupplementstoloweryourbody’sstresshormoneproducGon,likelicoriceorphosphaGdylserine
ThenyouhavetheMDs
FortreaGngchronicfaGgueandfibromyalgia,convenGonalmedicaltreatmentisnotoriouslyineffecGveandthereisaseverepaucityofresearch-provenmethodsforimprovingenergylevels.
– OneexcepGon:WhenfaGgueisoccurringasasideeffectofsomeothercondiGon,suchasaninfecGon,theycanbeeffecGveinhelping.
– Butoverall,conven1onalmainstreammedicinehasvirtuallynothingtoofferthoselookingtoimprovetheirenergylevels.
– Youcanexpecttogetsleepingpills,an1depressants,andan1-anxietydrugs.JusttotreatSYMPTOMS.
BoththeMDsandalternaGvepracGGoners(a.k.a.
adrenalfaGguers)areoperaGnginapathology-focusedparadigm
Theydiagnoseasicknessandthenseektotreatitwitheitherdrugsorsupplements.
Summingup
• Youhavethetypicalcommonsensedietandexercisefocusedadvicethatwe’veallheardandtriedmanyGmesbefore.
• YouhavetheadrenalfaGguerswhowillsendyouhomewithalaundrylistofsupplementstotaketofixyouradrenals.
• YouhaveMDs,whowillmostlikelysendyouhomewitheithernothingorananGdepressant.
That’sit!!!
Ijustsummedupprenymuch
everythingyoucanfindonthesubjectofimprovingyourenergylevels.That’s
prenymucheverythingout
there.
AndIdidNOTlikewhatIwasseeingoutthere…
IwassickandGredofhearingallthesameoldstuffthateveryonehasalreadyheardathousandGmesbefore…
IwassickandGredofhearingallthesameoldstuffthateveryonehasalreadyheardathousandGmesbefore…
• Govegan• Eat5-6smallmeals
throughouttheday• Reducestress• Takeanapeachday• Drinkmorewater• TakeamulGvitamin
• EatanutriGousdiet• Doexercise• Sleep8hourseachnight• Getridofgluten• Getridofdairy• Getridofsugar• Getridofcoffeeandcaffeine
IwassickandGredofpeoplejustbeinghandedabunchofsupplementsordrugstotaketofixsomeSYMPTOMSwithoutactuallyaddressingtherootcauseoftheproblem…
SoIdecidedtocreate…
thefirstandonlyscien1fic,evidence-basedblueprinttoenhancingenergylevels.
Solet’sgetintowhatthatsystemisallabout…
I’mgoingtotellyouaboutthetwomostessenGalprinciplesyouneedtoimplementinyourlifeif
youwanttoenhanceyourenergylevels.
• GoodnutriGon
ReallythereareTWOseparatekindsofthingsthatarehealthyforus:
1. CellularRegenerators
• Sleep• Adequatefoodintake
(calories+macros/micros)
• De-stressing• PlayandrelaxaGon• Adequatewaterintake
ReallythereareTWOseparatekindsofthingsthatarehealthyforus:
1. CellularRegenerators
• Sleep• Adequatefoodintake
(calories+macros/micros)
• De-stressing• PlayandrelaxaGon• Adequatewaterintake
2.MetabolicSGmulators/Stressors
• Exercise(allforms)
• Sunlight• Cold• Heat• Phytonutrients
TheTwoKeyPrinciplesofHighEnergyLevels
BuildingtheCellularEngine
CellularRegenera1on
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
CellularRegenera1on
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
CellularRegenera1on
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
CellularRegenera1on
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
Whatcreatesfa1gueisthelossofoneorbothofthesetwostates.
BuildingtheCellularEngine
CellularRegenera1on
Nowlet’stalkabouteachofthesetwoprinciplesmorein-depth…
CELLULARREGENERATION
TheFoundaGonalCellRegeneraGonStrategies
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits
3. Sleephygienehabits
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits
3. Sleephygienehabits4. Gentlemovement
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits
3. Sleephygienehabits4. Gentlemovement
5. AnG-stresshabits
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits3. Sleephygienehabits4. Gentlemovement5. AnG-stresshabits6. Work-rejuventaGonrhythm7. OpGmizedautophagy
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits3. Sleephygienehabits4. Gentlemovement5. AnG-stresshabits6. Work-rejuventaGonrhythm7. OpGmizedautophagy
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits3. Sleephygienehabits4. Gentlemovement5. AnG-stresshabits6. Work-rejuventaGonrhythm7. OpGmizedautophagy
OneoftheMostPowerfulAnG-AgingandEnergyBoosGngStrategies:AmplifyandMaintainHealthy
Autophagy
• Mostofuswhoareintohealthandfitnessalsowanttoknowhowwecaninhibittheagingprocess,soastohaveahealthyoldagefreeofillness,andhopefullylivealongGme.We’reawareoftheusualhealthypracGcessuchascleandiet,exercise,agoodnight’ssleep,limiGngtheuseofalcohol,ensuringwe’rewellnourishedwithvitamins,andsoon.ButwesGllage.Whatfurthermeasurescanwetaketoslowagingandpreventage-relateddecreaseinenergy(orevenenhanceourenergylevelsasweage)?
• EnhancingautophagyisoneoftheabsolutemostpowerfulanG-agingandenergybuildingstrategies….
Autophagyistheprocessofcellular“self-eaGng”thatoccursinallanimalsregularly,andisincreasedbyfasGng.Inaging,cellular“junk”,suchasmalfuncGoningmitochondria,misfoldedproteins,anddamagedorganellesaccumulate,causingthemaladiesofaging.ButthisjunkaccumulatespreciselybecausetheorganismisunabletoiniGateandmaintainautophagy.
• Whenautophagyisnotworkingwell,thatmeansyouarefuncGoningTODAYonYESTERDAY’SCELLCOMPONENTS.– ThatmeanspronenesstodiseaseandLOWERENERGYlevels.
• ThisstrategyisbasedonthecriGcalknowledgethatexcepGonallylong-livedlabanimals,thosethathavelifespansthataredoubleandmorethanthoseoftheshorter-livedvarieGes,havemutaGonsthatincreasetheprocessofAUTOPHAGY.
• Theseanimalsthatlivetwiceaslongormorethannormalanimalsdoeventuallydie.Butthefactthatincreasedautophagyextendstheirlivesshowsthatitisthemostimportant,thelimi0ngfactorinlifespan.– Again,themorejunkthatbuildsupandthefasteritbuildsup,notonlyagesyou,butdamagesyourcells’abilitytoproduceenergyefficiently.
• Invirtuallyallorganismstestedsofar(andthere’snoreasontobelievethathumansareanexcepGon)interminentfasGngextendslifespan,o[endramaGcally.
• ButwhydoesIFdothis?ManyanimalstudiesindicatethatAUTOPHAGYisthekeymechanism.
• Invirtuallyallorganismstestedsofar(andthere’snoreasontobelievethathumansareanexcepGon)interminentfasGngextendslifespan,o[endramaGcally.
• ButwhydoesIFdothis?ManyanimalstudiesindicatethatAUTOPHAGYisthekeymechanism.
• It’sbeenshownthatcellsfromlong-livedindividuals,i.e.centenarians,havehigherratesofautophagythanthemerelyold(75years).
• Conversely,diminishedautophagyplaysamajorroleinaging.
• Thinkaboutwhyyoungpeople(children)arebursGngwithenergy,andwhyweloseenergyaswegetolder…
• Maintainingcleancellsisimportanttoslowingagingandmaintainhealthymitochondria(i.e.highenergylevels)aswegetolder.
Themitochondrialtheoryofaginganemptstoaccountforagingbytheincreasednumberofdamaged,malfuncGoning,andfree-radical-producingmitochondria.• However,undernormal,healthycondi1ons,autophagy
removesandrecyclesthesemitochondria,soamorefundamentalreasonforagingisrepressedautophagy.
RepressedAutophagy!
AcceleratedAgingand
BluntedEnergyLevels
• KEYPOINT:AutophagyoccurswhenbloodlevelsofaminoacidsDROP.I.e.ItoccursAWAYfromFEEDINGperiods,duringFASTINGperiods.
• Inotherwords,itusuallyoccurswhilewesleep!
Thekey:toavoidagingandfaGgue,onemustgothroughperiodsofGmeofastrongbreakdowninGssue(autophagy),followedbyarigorousbuildingupagainofthesameGssue(anabolism).
Inthisway,thebodyisrejuvenated,sincetheGssuesthatarebrokendownareold,damagedmitochondria,misfoldedproteins,andothercellulardebris.
Andnewhealthymitochondria(cellularpowerplants)areBUILT!
3WaysIWanttoShareWithYouToAmplifyAutophagyandBoostYour
CellularRejuvenaGon
1. Amplifycircadianrhythm
2. AmplefasGngwindoweachnight
3. WaterattherightGme
• Normally,autophagyinhumansrisesanddeclineswithastrongdailyrhythm.SinceautophagyisupregulatedbyfasGng(orstarvaGon),itstronglyincreasesatnightandintheearlymorning,sincenofoodistakenduringthenight.
• Humansandotherorganismsexhibitastrongdiurnalrhythmofanabolismandcatabolism.Bothareequallynecessarytolifeandhealth.Withdisruptedcircadianrhythm,however,thatrhythmdeclinesinamplitude.Atnight,whenautophagyshouldbestronglyac1vated,itisonlyweaklysoornotatall.Intheday,whenanabolismshouldbeatfullspeed,agingweakenstheprocess.
• Alsoduetothecircadianrhythminautophagy,levelsofglutathione,atripepGdethatisthebody’smostimportantanGoxidant,risesandfalls.Theliver,forexample,maycontainasmuchas100%moreglutathioneduringthedayasintheearlymorning.
• Asaconsequenceoftheage-relateddeclineinautophagy,theaminoacidsthatarenecessaryforthesynthesisofglutathionefall,andnotenoughglutathioneisproduced.SinceglutathioneisanimportantanGoxidant,ifcellsdon’tmakeenough,freeradicalsbecomeabundantandastateofoxidaGvestressensues,andbasicallythebodycannotregenerateproperlyeachnightandyouAGEfasterandyourenergylevelsslowlyerode.
• OxidaGvestressinturncausesautophagytodecline,sowehaveaviciouscycleoflessautophagy,moreoxidaGvestress,evenlessautophagy,andsoon.
• Themoreyouamplifythiscircadianrhythmofanabolismandcatabolism,themoreyoupreserveeffec1veautophagy,themoreyouenhanceenergylevelsandlivelong.
AutophagyandCircadianRhythm
Blunteddiurnalcyclingofanabolism
andcatabolism
AutophagyandCircadianRhythm
Disruptedcircadianrhythm
Impairedautophagy
Lowenergyand
lifespan
OpGmaldiurnalcyclingofanabolism
andcatabolism
OpGmalcircadianrhythm
Enhancedautophagy
Highenergyand
lifespan
• ThemainsignalforautophagytostartandtoincreaseisdecreasedconcentraGonoftheaminoacidleucineintheblood.Readersmayrecognizeleucineasakeysignalingmoleculeforthegrowthofmuscle;theoppositeoccurswithleucinetoo,namelydecreasedconcentraGonsignalsformuscletobebrokendown.
• Here’sthekeypoint.AsmenGoned,autophagyisregulatedbylevelsofleucineintheblood,butwhenourcircadianrhythmisdysregulatedorwe’reunhealthyorwe’reolder…theabilitytorespondtoleucinebyincreasingautophagydecreases.Thecellsinanagingorunhealthybodysimplycannotturnautophagyonatthesamelevelthatwouldturnitoninyouthfulcells.
• Here’sthetrick:decreaselevelsofleucineduringthefasGngphasesothatevenwithdiminishedautophagycapacity,autophagyisstarted.
• Howdoyoudothis?Verysimple:DRINKWATERatnightorinthemorning.Thiswilldilutethebloodstreamandhencetheleucineinit,causingautophagytobestartedand/orincreased.Thusmorecysteinewillentertheblood,glutathionewillbemadefromit,andoxida1vestressdecreased.
SlowAgingByAmplifyingAutophagy(withWATER)
• ThemainsignalforautophagytostartandtoincreaseisdecreasedconcentraGonoftheaminoacidleucineintheblood.Readersmayrecognizeleucineasakeysignalingmoleculeforthegrowthofmuscle;theoppositeoccurswithleucinetoo,namelydecreasedconcentraGonsignalsformuscletobebrokendown.
• Here’sthekeypoint.AsmenGoned,autophagyisregulatedbylevelsofleucineintheblood,butwhenourcircadianrhythmisdysregulatedorwe’reunhealthyorwe’reolder…theabilitytorespondtoleucinebyincreasingautophagydecreases.Thecellsinanagingorunhealthybodysimplycannotturnautophagyonatthesamelevelthatwouldturnitoninyouthfulcells.
• Here’sthetrick:decreaselevelsofleucineduringthefasGngphasesothatevenwithdiminishedautophagycapacity,autophagyisstarted.
• Howdoyoudothis?Verysimple:DRINKWATERatnightorinthemorning.Thiswilldilutethebloodstreamandhencetheleucineinit,causingautophagytobestartedand/orincreased.Thusmorecysteinewillentertheblood,glutathionewillbemadefromit,andoxida1vestressdecreased.
SlowAgingByAmplifyingAutophagy(withWATER)
Oneofthemajorfactorsinillness,disease,obesity,andfaGgueinthemodernworldischronicallydisruptedcircadianrhythm,orthebodyclock.
Abigreasonwhydisruptedcircadianrhythmislinkedtosomanydiseasesfromcancer,toAlzheimer’s,toobesity,tofaGgue…IsthatitREPRESSESautophagy.
HowArGficialLightDisruptsAutophagy
HowArGficialLightWrecksYourBodyandYourEnergy
CircadianDisrup1on+Decreased
Prolac1n
HowArGficialLightWrecksYourBodyandYourEnergy
CircadianDisrup1on+Decreased
Prolac1n
HowArGficialLightWrecksYourBodyandYourEnergy
Inhibitedgrowthhormonesurge+inhibitedautophagy
CircadianDisrup1on+Decreased
Prolac1n
HowArGficialLightWrecksYourBodyandYourEnergy
Inhibitedgrowthhormonesurge+inhibitedautophagy
Acceleratedaging+Blunted
energylevels
Snackinga[erdinner…Effectoncircadiancycles
Ifyouchoosetoeatwithin3-4hoursofsleepyouwillSUPPRESSthehormonesthatareneededtoturnonautophagyatnight.
Snackinga[erdinner…Effectoncircadiancycles
• Doyoueatdinnerlateatnight?Ifso,youmaybesubtlyshi[ingyourbodytowardsfatgain.• "RikaYokoyama,MS,andcolleaguesfromtheHealthCareFoodResearchLaboratoriesoftheKao
CorporaGoninTokyo,Japan,comparedtheeffectsofearlyandlatemealsinacrossoverstudyof10healthyJapanesemen.Themenconsumedlunchat1:00pmandbreakfastthefollowingdayat8:00am;theyhaddinnerat7:00pmintheearlydinner(ED)condiGonandat10:00pminthelatedinner(LD)condiGon.Allmealswerethesame,andwereconsumedinarespiratorychamber,wherethesubjects'energyexpenditureandfueluGlizaGonweremeasuredfrom12:30pmunGl11:30amthenextday.
• IntheEDcondiGon,average23-hourenergyexpenditurewas1885(±231)calories;intheLDcondiGonitwas1837(±228)calories(P<.05).
• "Wesawasharpdeclineinpostprandialenergyexpenditure,ordiet-inducedthermogenesis(DIT),duringsleepapertheLDcondi1on.IntheEDcondiGon,thedeclinewasmoremoderate,"Ms.YokoyamatoldMedscapeMedicalNews."Presumably,thatwasbecauseintheEDcondiGon,moreGmeelapsedbetweendinnerandbedGme.However,wecouldnotidenGfythereasontheDITdeclinedsosharplyduringsleepa[erthelatedinner."NorcouldthedifferencesbetracedtovariaGonsinphysicalacGvity;infraredmoGonsensorsintherespiratorychamberdidnotdetectanychangesinphysicalacGvitybetweenthecondiGons,"sheexplained.
• InsulinandbloodglucoselevelsweremarkedlyhigherintheLDthanintheEDcondiGona[erdinner(P<.01).FreefanyacidswerealsohigherintheLDcondiGon,andremainedelevatedunGlbreakfastthefollowingday.Theauthorsconcludedthatea1ngdinnerlatewasassociatedwithlowertotalenergyexpenditure,hyperinsulinemia,andhyperglycemia,whichover1mecouldresultinobesity."
LateDinnerPredisposestoFatGain
• Phenomenalnewstudy!
• “ASmartphoneAppRevealsErra1cDiurnalEa1ngPaEernsinHumansthatCanBeModulatedforHealthBenefits.”(PublishedinthejournalCellMetabolism).
• TheyusedanapptomonitorthetypicalfeedingpanernsofmostAmericans,andfoundsomeveryimportantthingsthatmanyotherstudydesignshavenotbeenabletopickup.
Here'ssomeofthemostimportantfindings:
Here'ssomeofthemostimportantfindings:
1. Mostpeoplehaveadailyfeedingwindowof15hoursorlonger.(ALONGfeedingwindowthatextendsalmostfromimmediatelya[ermorningwakeuptothemomentsbeforesleep).
Here'ssomeofthemostimportantfindings:
1. Mostpeoplehaveadailyfeedingwindowof15hoursorlonger.(ALONGfeedingwindowthatextendsalmostfromimmediatelya[ermorningwakeuptothemomentsbeforesleep).
2. Mostpeoplefasteachdayonlyforthe1methey'reinbed(just8or9hours).Notethatformostpeople,thisperiodofnotconsumingcoincideswithcompletesedentariness(sleep),whichallbuteliminatesanyextendedperiodsofBURNINGoffenergywithoutconsumingany.MostpeopleareessenGallyALWAYSinastatewheretheirenergystoresaretoppedout,andtheyneverreallyputtheirbodyinastatewheretappingintobodilyreservesgetsswitchedonforanysignificantlengthofGme.It'ssortoflikestoppingatthegasstaGona[erevery25milesyoudrive.You'realwaystoppingitoffwithouteverreallyfullyusingthetankofgasthat'sinthere.
Here'ssomeofthemostimportantfindings:
1. Mostpeoplehaveadailyfeedingwindowof15hoursorlonger.(ALONGfeedingwindowthatextendsalmostfromimmediatelya[ermorningwakeuptothemomentsbeforesleep).
2. Mostpeoplefasteachdayonlyforthe1methey'reinbed(just8or9hours).Notethatformostpeople,thisperiodofnotconsumingcoincideswithcompletesedentariness(sleep),whichallbuteliminatesanyextendedperiodsofBURNINGoffenergywithoutconsumingany.MostpeopleareessenGallyALWAYSinastatewheretheirenergystoresaretoppedout,andtheyneverreallyputtheirbodyinastatewheretappingintobodilyreservesgetsswitchedonforanysignificantlengthofGme.It'ssortoflikestoppingatthegasstaGona[erevery25milesyoudrive.You'realwaystoppingitoffwithouteverreallyfullyusingthetankofgasthat'sinthere.
3. Mostpeopleconsumethealargepor1onoftheirdailycaloriesintheeveningsaper6pm(a[ersunsetinmanycases),inaddiGontotheverylongfeedingwindows.
Here'ssomeofthemostimportantfindings:
1. Mostpeoplehaveadailyfeedingwindowof15hoursorlonger.(ALONGfeedingwindowthatextendsalmostfromimmediatelya[ermorningwakeuptothemomentsbeforesleep).
2. Mostpeoplefasteachdayonlyforthe1methey'reinbed(just8or9hours).Notethatformostpeople,thisperiodofnotconsumingcoincideswithcompletesedentariness(sleep),whichallbuteliminatesanyextendedperiodsofBURNINGoffenergywithoutconsumingany.MostpeopleareessenGallyALWAYSinastatewheretheirenergystoresaretoppedout,andtheyneverreallyputtheirbodyinastatewheretappingintobodilyreservesgetsswitchedonforanysignificantlengthofGme.It'ssortoflikestoppingatthegasstaGona[erevery25milesyoudrive.You'realwaystoppingitoffwithouteverreallyfullyusingthetankofgasthat'sinthere.
3. Mostpeopleconsumethealargepor1onoftheirdailycaloriesintheeveningsaper6pm(a[ersunsetinmanycases),inaddiGontotheverylongfeedingwindows.
4. Therewassignificantvaria1oninmeal1mingpaEernsfromweekdaystoweekends,whichtheylikenedtometabolicjetlag.
Here'ssomeofthemostimportantfindings:
1. Mostpeoplehaveadailyfeedingwindowof15hoursorlonger.(ALONGfeedingwindowthatextendsalmostfromimmediatelya[ermorningwakeuptothemomentsbeforesleep).
2. Mostpeoplefasteachdayonlyforthe1methey'reinbed(just8or9hours).Notethatformostpeople,thisperiodofnotconsumingcoincideswithcompletesedentariness(sleep),whichallbuteliminatesanyextendedperiodsofBURNINGoffenergywithoutconsumingany.MostpeopleareessenGallyALWAYSinastatewheretheirenergystoresaretoppedout,andtheyneverreallyputtheirbodyinastatewheretappingintobodilyreservesgetsswitchedonforanysignificantlengthofGme.It'ssortoflikestoppingatthegasstaGona[erevery25milesyoudrive.You'realwaystoppingitoffwithouteverreallyfullyusingthetankofgasthat'sinthere.
3. Mostpeopleconsumethealargepor1onoftheirdailycaloriesintheeveningsaper6pm(a[ersunsetinmanycases),inaddiGontotheverylongfeedingwindows.
4. Therewassignificantvaria1oninmeal1mingpaEernsfromweekdaystoweekends,whichtheylikenedtometabolicjetlag.
5. TheyfoundthatthemajorityofcaloriespeopleconsumeishappeninginBETWEENMEALSassnacks.(Andmanypeopleareunconsciousofhowmuchthey'reactuallyconsuminginbetweenmeals).
6. Shorterfeedingwindowshavebigbenefits!WhenoverweightindividualsSHORTENEDtheirfeedingwindowfromgreaterthan14hourfeedingwindowsto10-11hourfeedingwindows,theyLOSTFAT,SLEPTBETTER,andIMPROVEDTHEIRENERGY.
Here'ssomeofthemostimportantfindings:
1. Mostpeoplehaveadailyfeedingwindowof15hoursorlonger.(ALONGfeedingwindowthatextendsalmostfromimmediatelya[ermorningwakeuptothemomentsbeforesleep).
2. Mostpeoplefasteachdayonlyforthe1methey'reinbed(just8or9hours).Notethatformostpeople,thisperiodofnotconsumingcoincideswithcompletesedentariness(sleep),whichallbuteliminatesanyextendedperiodsofBURNINGoffenergywithoutconsumingany.MostpeopleareessenGallyALWAYSinastatewheretheirenergystoresaretoppedout,andtheyneverreallyputtheirbodyinastatewheretappingintobodilyreservesgetsswitchedonforanysignificantlengthofGme.It'ssortoflikestoppingatthegasstaGona[erevery25milesyoudrive.You'realwaystoppingitoffwithouteverreallyfullyusingthetankofgasthat'sinthere.
3. Mostpeopleconsumethealargepor1onoftheirdailycaloriesintheeveningsaper6pm(a[ersunsetinmanycases),inaddiGontotheverylongfeedingwindows.
4. Therewassignificantvaria1oninmeal1mingpaEernsfromweekdaystoweekends,whichtheylikenedtometabolicjetlag.
5. TheyfoundthatthemajorityofcaloriespeopleconsumeishappeninginBETWEENMEALSassnacks.(Andmanypeopleareunconsciousofhowmuchthey'reactuallyconsuminginbetweenmeals).
6. Shorterfeedingwindowshavebigbenefits!WhenoverweightindividualsSHORTENEDtheirfeedingwindowfromgreaterthan14hourfeedingwindowsto10-11hourfeedingwindows,theyLOSTFAT,SLEPTBETTER,andIMPROVEDTHEIRENERGY.
3WaysToAmplifyAutophagyandBoostYourCellularRejuvenaGon
1. Amplifycircadianrhythm
2. AmplefasGngwindoweachnight
3. WaterattherightGme
ThisisjustONEoftheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits3. Sleephygienehabits4. Gentlemovement5. AnG-stresshabits6. Work-rejuventaGonrhythm7. OpGmizedautophagy
Step1ofOpGmalEnergyLevelsisHavingSolidCellRegeneraGonHabits
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits3. Sleephygienehabits4. Gentlemovement5. AnG-stresshabits6. Work-rejuventaGonrhythm7. OpGmizedautophagy
BUILDINGTHECELLULARENGINE
STEP2:BUILDINGYOURCELLULARENGINE
Mitochondriaarethepartofthecellthat“burn”thecalories(carbsandfats)andturnthemintoenergyforthecell.Wehave500-2,000percell!
WhatareMitochondria?TheCellularEnergyGenerator!
Ifyouansweryestothese,thenthatmayindicatelowmitochondrialfuncGon:
• DoyougetGredo[en?• Doyouhavealowmetabolism?
• Doyoulackenergyintheday?• Doyouhaveadisturbedcircadianrhythm?
(sleepyduringthedayand/orhavetroublesleepingatnight)• DoyouhavechronicinflammaGon?
SymptomsofLowMitochondrialFuncGon
Now,here’sthereallyincrediblepartthatmostpeopledon’tknow…Dependingonyourlifestylehabitsandenvironment,youhavetheabilitytodramaGcallyincreasetheSIZEandPOWERofthemitochondriainyourcells.AndyouevenhavetheabilitytoCREATEandBUILDNEWMITOCHONDRIAFROMSCRATCH,anddramaGcallyincreasetheamountofthesepowerplantsinyourcells.
Sothinkaboutthatformoment…inmostareasoflife,wecanonlyget10or20%improvement,butwithenergylevels,youcandoubleorTRIPLEyourenergylevels.
Nowyoumightstarttoseehowthisispossible.
Ifyouarelookingatthecellularengineinourcells,andyouhavetheabilitytoDOUBLEtheSIZEandPOWERofthemitochondriaofyourcells(theplacewhereenergyisbeingproduced),thenitmakeslogicalsensethatyoucanDOUBLEyourenergylevels.
Butitactuallygoesbeyondthat…remember,youalsohavetheabilitytoliterallycreateMOREmitochondriafromscratch.
Sonotonlyareyoubuildingbiggerandmorepowerfulcellularpowergenerators,butatthesameGme,youcanactuallygofromhavingsay500linlecellularenginesinyourcellto1,000.Thinkaboutthat…youcangofrom500SMALLlinleenergygeneratorsineachcellto750or1,000BIGPOWERFULENERGYGENERATORS!
• Mitochondriaarethecellularenergygenerators!
• Wehaveoverbetween500-2,000percell
WhyisMitochondrialBiogenesissoImportanttoIncreasingEnergyLevels?
BiggermitochondriaandMORE
mitochondria
BiggerCellularEngine
HighercapacitytoPRODUCEENERGY!
MoreMitochondria=BiggerCellEngine!
Withwelldesignedstrategies,youcangofrom500mitochondriainyourcellsto750or1,000ormore!
WhenyouincreasetheamountofmitochondriainyourcellsandtheSIZEandPOWERofthosemitochondria,youcanDOUBLEtheenergyproducingcapacityofyourcells!
TheHiddenKeyToHighEnergyLevels:MitochondrialGrowthandBiogenesis
ThebonomlinehereisthatifyoucanDOUBLEorTRIPLEtheSIZEandPOWERofyourcellularenergygenerators…whichisliketakingoutyourcar’sengineandreplacingitwithabigger,farmorepowerfulengine…Basically,youcanDOUBLEorTRIPLEtheamountofenergyyourbodyiscapableofproducing,andyoucanDOUBLEorTRIPLEyourenergylevels.
• TheonlyproblemistheyareverysensiGvetodamage…fromuncontrolledoxidaGvestress,whichresultsfromtoxicinsults,infecGons,allergens,stress,andjusteaGngtoomuchpoorqualityfood.
• Butevenmoreimportantlythanthat(andlepoutbymostpeople)…thebiggestfactoristhat,muchlikeaMUSCLE,mitochondriawillSHRINK(atrophy)andbecomeWEAKwhennots1mulatedthroughHORMETICSTRESSORS!
Theproblem…
• TheonlyproblemistheyareverysensiGvetodamage…fromuncontrolledoxidaGvestress,whichresultsfromtoxicinsults,infecGons,allergens,stress,andjusteaGngtoomuchpoorqualityfood.
• Butevenmoreimportantlythanthat…thebiggestfactoristhat,muchlikeaMUSCLE,mitochondriawillSHRINK(atrophy)andbecomeWEAKwhennots1mulatedthroughHORMESIS!
Theproblem…
WhattheheckisHORMESIS?
HORMESIS:MajorKeytoEnhancedHealth,Longevity,andENERGY
Oneofthemostimportant—ifnotthemostimportant
—strategyforhealthandenergyenhancement.
Candlevs.Fire(ametaphorforunderstandinghowhormesisworks)
“WindexGnguishesacandleandenergizesfire.Likewisewithrandomness,uncertainty,chaos:youwanttousethem,nothidefromthem.Youwanttobethefireandwishforthewind.”
--NassimNicholasTaleb
WhatisHormesis?
Hormesisistheprocessbywhichamildoracutestressorincreasesresistancetootherstressorsandincreasesthehealth,resilience,andvitalityoftheorganism.
• Itcanincreaseresistancetoavarietyofstresses,notonlytheonetowhichyouareexposed.
HormesisisMoreFamiliartoYouThanYouRealize
• Itmightsoundlikeaforeignconcept,butyou'remorefamiliarwithitthanyouthink.– Exerciseisaformofhormesis.
• It'sastressplaceduponthebodythatincreasesresistancetoanumberofotherstressors:physicalexerGon,cardiovasculardisease,depression,diabetes,age-relatedcogniGvedecline,neurodegeneraGvedisease,etc.
• Hormesisisbasicallyintroducinganacutestress(lowerdosestressor)tothebodythatsGmulatesthebodytoadaptandgrowmorefittobepreparedforgreaterloadsofthatstressor.
• Bybeingprepped,thebodycanbeshi[edintoastateofhigherperformanceasitmakesadaptaGonsthatbenefitwholeorganismhealth.
StressToleranceisTheKEYtoLongevity
• FromthediscussionsecGonofonescienGficstudyonthesubject:• “Stresstoleranceandlifespanextensionareremarkablycorrelated.The
contradictoryextensionoflifespanbyostensiblydeleteriouscondi1ons,andtheconcomitantinduc1onofstresstolerance,suggeststhatlifespanextensionmayoccurthroughthehorme1cinduc1onofdamage-bufferingcytoprotec1vemechanisms.[…]
• LifespanposesanevoluGonaryconundrum,asthegeneGcdeterminaGonoflifespanostensiblysuggestspost-reproducGveselecGon.Ourdatasuggeststhatlifespan-determininggenesdonotspecifylifespanperse,butrathertheac1vityofdamage-bufferingcytoprotec1vepathwaysnormallyengagedonlyinresponsetostresss1muli,suchastoxins.”
• ThesestressresponsesareacGvatedinthefaceofpotenGallydamagingsGmuli,suchasexercise,toxins,fasGng,andsolarradiaGon.
• Ifonewantsmoreenergy,greatervitalityandalongerlife,acGvaGonoftheseresponsesonaregularbasisisthewaytogo.
HormesisisTheBody’sWayofAdapGngtoaHarshEnvironment
Themechanismofhormesisappearstobeovercompensa+ontore-establishhomeostasis-whichisatechnicalwayofsaying
thatanorganismrespondstosmallstressesbybecomingmorerobusttoadapttoachallengingenvironment.
Inalargersense,hormesismayhelpexplainwhypeoplewholeadstrenuousliveswithplentyofmoderatephysicalchallengesmaybehealthierandlivelongerthanthoseinmorecomfortablecircumstances.
BOTHTOOLITTLEANDTOOMUCHSTRESSAREPROBLEMATIC
TheParadigmShi[
• Thereareboth“good”and“badstressors.”• WeNEEDampleexposuretohormeGcstressorstobeopGmallyhealthyandenergeGc!– (butBRIEFexposures,notchronicexposure!)
Hormesismaybethesinglemostimportantstrategytoincreaseyourmetabolichealthandboost
energylevels.
Hormesisisthebasisonwhichanynumberofinputscausesbenerhealth.
Itmightnotbegoingtoofartosaythathormesisisthevery
basisofhealth!
• Anyinputthatcausesbenerhealth,inputssuchasexercise,fruitsandvegetables,coldshowers,interminentfasGngandcalorierestricGon,ionizingradiaGonfromthesun,alloftheseworkbyproducingastress,hencetheyworkbyhormesis.– (Itmightinterestyoutoknowthatfruitsandvegetablesarehealth-givingpreciselybecausetheycontainsmallamountsoftoxicphytochemicals,fromwhichthebodymustdefenditself,broccolibeingaprimeexample.)
• TheoppositeofproducinghormeGcstresscanbeseeninthecouchpotatolifestylethatleadstoobesity,diabetes,heartdisease;failuretosubjectthebodytotherightamountofstressproducesillhealth.
TheAgeofHormesisandTheAgeofFragility
TheAgeofHormesis
Ourhumanancestorslivedandsurvivedinageswhenfoodmayhaveo[enbeenhardtocomeby,whenexerciseintheformofwalking,hunGng,building,gathering,andsoonweredailyrequiredacGviGes,andinwhichtheyateplantsthatcontainedtoxins.Itstandstoreasonthatwe’readaptedtothesecondi1ons,andanydevia1onfromthemispoten1allyinjurioustohealth.
TheAgeofANTI-Hormesis(Fragility)
Wenowliveinanageof,wemightcallit,anG-hormesis.Exerciseisnolongerarequirement,foodisavailablewheneverwewantit,andajunkfooddietexcludingdietaryphytochemicalsisthenormformany.Asaresult,wehavetheobesityepidemic,rampantdiabetesandheartdisease,andalltherest.
EVOLUTIONARYPERSPECTIVE:Notonlyarewedesignedtosurvivestressors,buttoTHRIVEwith
them!
• Inordertosurviveandreproduce,ourancestorhominidsspentmostoftheirwakinghoursworkingtofindfood,eitherby‘grazing’onplantsorbyhunGnganimals.
• TheywereREGULARLYexposedtophysicalaci1vty,occasionalfas1ng(duetofoodscarcity),noxiousplantphytochemicalsandtheelements(bothheatandcold).
• ALLofthesearehorme1cstressorsthatnotonlydon’tharmus,buthavePROFOUNDhealthBENEFITS!
• InterminentfasGngprotectsagainstobesity,diabetes,cancers,neurodegeneraGvediseases,andcanextendlifeinexperimentalanimalsby30%.
• Exercisedoesmuchthesame,andalsoimprovesneuralconnecGonsandnumber;thosewhoexerciseregularlycanliterallyexpandtheirbrainsandcogniGvecapacity,i.e.intelligence.
• Anotherexampleofhormesisisdietaryphytochemicals,whichareactually“noxious”.Cold,heatandotherhormeGcstressorscanalsosGmulatealotofthesamemolecularpathwaysasexercise.
EVOLUTIONARYPERSPECTIVE:Notonlyarewedesignedtosurvivestressors,buttoTHRIVEwith
them!
Now,here’sanimportantpointtounderstand:It’snotjustexercisethatdoesthis—lotsofthingsdo!
Andbyexposingyourbodytotheseformsofhormesis,yourbodymakesadapta1onsthatmakeitmoreenerge1c,moreresilient,andhealthier.(Justlikewithexercise!)
ExamplesofHormesis
1. Exercise(allsubtypes)2. InterminentfasGng3. Interminentnutrientcycling(i.e.carbs/fats/proteins)4. Cold5. Heat6. Redandnear-infraredlight7. Hypoxia8. Oxygenbankruptcy9. UVlight10. XenobioGcs(caffeine,nicoGne,alcohol,manydrugs)11. Dietaryphytochemicals(xenohormeGns)
ExamplesofHormesis
1. Exercise(allsubtypes)2. InterminentfasGng3. Interminentnutrientcycling(i.e.carbs/fats/proteins)4. Cold5. Heat6. Redandnear-infraredlight7. Hypoxia8. Oxygenbankruptcy9. UVlight10. XenobioGcs(caffeine,nicoGne,alcohol,manydrugs)11. Dietaryphytochemicals(xenohormeGns)
• AllofthesehavebetweendozensandTHOUSANDSofstudiesshowingprovenhealthbenefits.
• QuesGon:Howmanyofthesedoyouthinkmostpeopleuse?
HavingMULTIPLElayersofhormesisinyourlifeisamajorKEY
toopGmalhealthandenergy.
HowDoesHormesisRelatetoEnergyLevels?
Simple:ThebodyrespondstohormeGcstressorsbyBUILDINGUPtheCELLULARENGINE!
– Itbuildsbigger,morepowerfulmitochondria,andmoreofthem!
– Moremitochondriaandmorepowerfulmitochondria=biggercellengine=moreenergy!
Here’stheKEYPOINT:
ThemoreyourbodyhasbeenexposedtohormeGcstressorsandhadthechancetoadapttothem,themoreresilientyourbodybecomes.
…whichmeansthemoreopGmalyourmetabolichealthis,themoreresistanttodiseaseyourbodyis,andthemorecellularenergyyourcellsproduceandthemoreenergyyoufeel.
TheFragile-BulletproofSpectrum
BULLETPROOF
Avoidanceofall
stressorsRegularsystemaGcexposuretoawidevarietyofhormeGc
stressors
Again,thereareLOTSofDifferentTypesofHormesis
(anditwouldrequiremanyhoursoflecturetogooverallofthem)
• Exercise• Interminentfasts• Cold• Heat• Redlight• Hypoxia• Oxygenbankruptcy• Dietaryphytochemicals(xenohormeGns)
Solet’sjustexploreONEoftheseforthisvideo,togiveyouapowerfulnewstrategytoincrease
yourmitochondria
• Exercise• Interminentfasts• Cold• Heat• Redlight• Hypoxia• Oxygenbankruptcy• Dietaryphytochemicals(xenohormeGns)
WhatTypeofExerciseisBestforMitochondrialBiogenesis?
TheeffectofdifferentexerciseregimensonmitochondrialbiogenesisandperformanceTHESISFORDOCTORALDEGREEByNiklasPsilander,2014.OneofthemostprofoundadaptaGonstoendurancetrainingisincreasedmitochondrialfuncGonandcontentwithintheexercisingmuscles.MitochondrialqualityandquanGtyarecloselyrelatedtoseveraloftheposiGvehealtheffectsreporteda[ertraining.HighmitochondrialcontentstronglycorrelateswithmuscleoxidaGvecapacityandenduranceperformance.Eventhoughitiswellknownthatendurancetrainingincreasesmitochondrialcontent,itisunclearwhichtypeoftrainingisthemostefficienttopromotemitochondrialbiogenesis.Therefore,thebasisforcurrentexerciserecommendaGonsrelaGvetomitochondrialbiogenesisispoororabsent.Thus,themainobjecGveofthisthesiswastoevaluatetheeffectofdifferenttrainingstrategiesonmitochondrialbiogenesis.
WhatTypeofExerciseisBestforMitochondrialBiogenesis?
PGC-1αisakeyregulatorofmitochondrialbiogenesisandtheexpressionofPGC-1αcanthereforebeusedasamarkerofthisprocess.
StudyI:TheexpressionofPGC-1αandrelatedgeneswereexamineda[er90minofconGnuousandintervalexerciseinuntrainedsubjects.TheexerciseprotocolsinfluencedtheexpressionofgenesinvolvedinmitochondrialbiogenesisandoxidaGvemetabolisminasimilarmanner.Bothintervalandcon1nuousexercisewerepotenttrainingstrategiesforrela1velysedentaryindividuals.
StudyII:TheexpressionofPGC-1αandrelatedgeneswereexamineda[erlow-volumesprintinterval(SIT)andhigh-volumeinterval(IE)exerciseinhighlytrainedcyclists.SITinducedasimilarincreaseinPGC-1αexpressionasIEdespiteamuchlowerGmecommitmentandworkcompleted.Sprintintervalexercisemight,therefore,beaGmeefficienttrainingstrategyforhighlytrainedindividuals.
StudyIII:TheexpressionofPGC-1αandrelatedgenes,aswellastheacGvityofupstreamproteins,wereexamineda[erconcurrent(ER:cycling+legpress)andsingle-mode(E:cyclingonly)exerciseinuntrainedsubjects.PGC-1αexpressiondoubledaperERcomparedwithE.Itwasconcludedthatconcurrenttrainingmightbebeneficialformitochondrialbiogenesisinuntrainedindividuals.
StudyIV:TheexpressionofPGC-1αandrelatedgeneswereexamineda[erexerciseperformedwithlow(LG)andnormal(NG)muscleglycogeninwell-trainedcyclists.PGC-1αexpressionincreasedapproximatelythree1mesmoreaperLGcomparedwithNG.Thisfindingsuggestedthatlowglycogenexerciseisapotentinducerofmitochondrialbiogenesisinwell-trainedindividuals.
SummingUp:ExerciseandMitochondrialBiogenesis
Summary:ExerciseandMitochondrialBiogenesis
Untrainedsubjects
• ConGnuousandintervalexercisehaveasimilareffectonPGC-1α,andothergenesregulaGngmitochondrialbiogenesis,iftheduraGonandworkdonearethesame.
• ConcurrentresistanceandenduranceexercisedramaGcallyenhancesthesignalingpathwayofmitochondrialbiogenesis(overenduranceexercisealone).
Trainedsubjects
• SprintintervaltrainingisapowerfulinducerofPGC-1α,andothergenesregulaGngmitochondrialbiogenesis.Likelyneedstobedonefasted.(Addedbonus:LepGnmimeGc,whichmayhavepowerfulimplicaGonsforincreasedenergylevelsandfatloss.)(Note:Doesnotactuallyneedtobe“sprinGng”—sprinteffortsonacyclealsowork.)
• Eightweeksofconcurrentstrengthandendurancetrainingdoesnotenhancemitochondrialcontent(CS-acGvity)orperformance
• ExercisewithlowmuscleglycogenenhancestheexpressionofPGC-1α,andothergenesregulaGngmitochondrialbiogenesis
Generalfinding
• Bothexercisetypeandglycogenstatusinthemuscleplayaroleinmitochondrialbiogenesis.
Summary:ExerciseandMitochondrialBiogenesis
Untrainedsubjects
• ConGnuousandintervalexercisehaveasimilareffectonPGC-1α,andothergenesregulaGngmitochondrialbiogenesis,iftheduraGonandworkdonearethesame.
• ConcurrentresistanceandenduranceexercisedramaGcallyenhancesthesignalingpathwayofmitochondrialbiogenesis(overenduranceexercisealone).
Trainedsubjects
• SprintintervaltrainingisapowerfulinducerofPGC-1α,andothergenesregulaGngmitochondrialbiogenesis.Likelyneedstobedonefasted.(Addedbonus:LepGnmimeGc,whichmayhavepowerfulimplicaGonsforincreasedenergylevelsandfatloss.)(Note:Doesnotactuallyneedtobe“sprinGng”—sprinteffortsonacyclealsowork.)
• Eightweeksofconcurrentstrengthandendurancetrainingdoesnotenhancemitochondrialcontent(CS-acGvity)orperformance
• ExercisewithlowmuscleglycogenenhancestheexpressionofPGC-1α,andothergenesregulaGngmitochondrialbiogenesis
Generalfinding
• Bothexercisetypeandglycogenstatusinthemuscleplayaroleinmitochondrialbiogenesis.
Summary:ExerciseandMitochondrialBiogenesis
Untrainedsubjects
• ConGnuousandintervalexercisehaveasimilareffectonPGC-1α,andothergenesregulaGngmitochondrialbiogenesis,iftheduraGonandworkdonearethesame.
• ConcurrentresistanceandenduranceexercisedramaGcallyenhancesthesignalingpathwayofmitochondrialbiogenesis(overenduranceexercisealone).
Trainedsubjects
• SprintintervaltrainingisapowerfulinducerofPGC-1α,andothergenesregulaGngmitochondrialbiogenesis.Likelyneedstobedonefasted.(Addedbonus:LepGnmimeGc,whichmayhavepowerfulimplicaGonsforincreasedenergylevelsandfatloss.)(Note:Doesnotactuallyneedtobe“sprinGng”—sprinteffortsonacyclealsowork.)
• Eightweeksofconcurrentstrengthandendurancetrainingdoesnotenhancemitochondrialcontent(CS-acGvity)orperformance
• ExercisewithlowmuscleglycogenenhancestheexpressionofPGC-1α,andothergenesregulaGngmitochondrialbiogenesis
Generalfinding
• Bothexercisetypeandglycogenstatusinthemuscleplayaroleinmitochondrialbiogenesis.
ANYtypeofexercisewillworktoincreasemitochondrialbiogenesis.Butcombina1onexerciseofbothresistanceexerciseandenduranceorHIITismosteffec1ve.
YouwillhavetodoeitherHIITorSIT.ExperimentwithdoingHIITorSITworkoutsaperoccasionalintermiEentfastsand/orthenightlyfast.
BoEomline:Areyoucurrentlysedentaryanduntrained?Areyoucurrentlyaworkoutwarriorwhoexerciseclosetoeveryday(andyou’realreadyingoodmetabolichealth)?
BoEomline:Areyoucurrentlysedentaryanduntrained)?
BoEomline:Areyoucurrentlysedentaryanduntrained)?
SummingUp:ExerciseandMitochondrialBiogenesis
ThisisjustONEexampleofastrategytoboost
mitochondrialbiogenesis.
ThereareliterallyDOZENSofotherstrategiesthatarescienGficallyproventoboostmitochondrialbiogenesis—andI’veoutlinedthemallinmyprogram,TheEnergyBlueprint.
AND…ManyofthemareSYNERGISTIC!SoyoucanlayerthemtogethertomakethemWAYMOREPOWERFUL!
ExamplesofHormesis
• Exercise• Interminentfasts• Cold• Heat• Redlight• Hypoxia• Oxygenbankruptcy• Dietaryphytochemicals(xenohormeGns)
ExamplesofHormesis
• Exercise• Interminentfasts• Cold• Heat• Redlight• Hypoxia• Oxygenbankruptcy• Dietaryphytochemicals(xenohormeGns)
COLD–EssenGaltoOpGmalEnergyandHealth
HydrotherapyhasactuallybeeninusesinceancientGmesasawaytobalancethebodyand
mind.
AccordingtoHippocrates,watertherapy‘allayslassitude’(physicalor
mentalweakness).
HowDoesHydrotherapyWork?• ThroughoutourmillionsofyearsofevoluGon,primateshaveendured
physiologicalstressorsliketemporarycoldandheattemperaturechangesasapartofdailylife.HydrotherapyisdesignedtotakeadvantageofthenaturalbodyreacGontothesechangesinordertomakethebodystronger.
• Applyingwaterofdifferenttemperaturestoourskincanchangeourphysiologyandmood.Whenhumanstakeacoldswim,onceovertheiniGalshockofthecold,itisusuallyveryinvigoraGng.
• Thisisbecausewetandcoldcausesoursurfacevesselstovasoconstrict(Gghtenup)makingbloodmovefromthesurfaceofyourbodytothecore,asameanstoconserveheat.Notonlydoesitconserveheat,italsoreflexivelybathesthebrainandvitalorgansinfreshblood.ThismovementwillbringnutriGon,oxygenandalsohelpgentlydetoxifythearea.Warmwaterwillmakethevesselsvasodilate(relax)whichwillbringblooduptothesurface.Thishelpsbloodmoveback,awayfromthecore,cleaningoutthecore.
• Medicalresearchhassupportedtheuseofhotandcoldbathsaswell.
• Decreasesinstresshormones(likecorGsol)havebeenreportedwithwaterbathing(Todaetal.,2006).Ithasalsobeenshownthatwaterbathingmayalsohelpthebalanceofthefeelgoodneurotransminerserotonin(MarzsziGetal.,2007).
• FootbathshavebeenshowntoinducerelaxaGonbydecreasingthatstressresponse,whereithasbeennotedthatthesympatheGcnervoussystem(the‘fightorflight’partofournervoussystem)wasabletocalmdown(Yamamotoetal.,2008).ThomasJeffersoniswellknowntohaveusedacoldfootbatheverymorningfor60yearstomaintainhisgoodhealth.
• AccordingtothemostrecentstaGsGcsfromtheCDC,oneoutofeverytwentyAmericanssuffersfromdepression.
• Afull27%ofthesepeoplereportthattheircondiGonissobadthatitpreventsthemfromperformingeverydayacGviGesorassociaGngwithothers.Ifyou’reeversufferedfromevenmilddepression,youknowhowdifficulttheexperiencecanbe.InaworldasbeauGfulandvariedandabundantasours,anyemoGonaloffsetthatdisconnectsyoufromdailyexperienceisatragedy.
• ThemainsoluGontothismonumentalhealthissuethat’sofferedbyconvenGonalmedicineisprescripGonanGdepressantdrugs.230millionprescripGonsarefilledforthesedrugseveryyear—anumberwhichdoublesnearlyeverytenyears—andaccordingtostudies,theireffecGvenessisextremelypoor.Unfortunately,thisfailureiscoveredbyupdrugcompanies,whichmakebillionsofdollarsperyearfromthesaleofanGdepressants.
• But,unbeknownsttomostpeople,therearenaturaltreatmentsolu1onsfordepressionthatarenaturalandfast-ac0ng.Oneofthemostpromisingofalliscoldwaterexposure.
• Youheardthatright—frequentexposuretocoldwatercanalleviatedepressioninasurprisinglyshortamountofGme.
• Moreandmorepeoplearediscoveringthatcoldwatertherapycanchangeyourlife.
• ThispracGceofcoldexposureisnotwithouthistoricalprecedent;spiritualandmedicaltradiGonsthroughoutrecordedhistoryhavelaudedthevirtueofcoldwaterbathing(yogiswouldtravelvastdistancestofindsolaceintheglacialwatersofHimalayanwaterfalls).
• Hippocratesbelievedthathydrotherapy“allaysphysicalandmentalweakness,”andthetradiGonplayedanimportantrolein19thcenturyGermannaturopathy.
ColdWaterExposureCanAlleviateDepression
• Onlyrecently,though,hasmodernmedicalsciencehadanythingposiGvetosayaboutit.ResearchersfromtheVirginiaCommonwealthUniversitySchoolofMedicinereportedthatdepressedpaGentsexperiencedasignificantmoodimprovementbecauseofcoldwaterexposure.Theysimplytooka2-3minuteshowerat68degreesFahrenheit,onceortwicedailyfortwomonths.
• OtherresearchhasalsodemonstratedthathydrotherapyisremarkablyeffecGveatrelievingdepression’ssymptomsandrelatedcondiGons.OnestudyfoundthepracGcetobemoreeffec1veatameliora1nganxietyandmoodinstabilitythanPaxil(aleadingpharmaceu1cal),andanotherfoundthatcoldwaterexposureworkswondersforbothdepressionandchronicfa1gue.
ColdAsEffecGveasAnG-AnxietyDrugs
or…
• ColdwaterexposurethushelpsusreturntoanaturalstateofbalancebyacGvaGngthesympatheGcnervoussystem,increasingbloodflowtothebrainandcore,andincreasingbloodlevelsofbeta-endorphinandnoradrenaline.ItalsohelpscalmsystemicinflammaGon,whichisstronglylinkedtodepression.Andbytheway,exercise(whichcouldalsobeviewedasakindofself-inducedphysiologicalstressor)alsotriggerssomeoftheseposiGveeffects—soanexerciserouGnefollowedbyacoldshowercandeliverapowerfulone-twopunchtodepression.
• Here’sanotherfascinaGngeffectofcoldshowers:becauseyourskinhasfarmorecoldreceptorsthanwarmreceptors,suddenexposuretocoldwatersendswhatresearcherscall“anoverwhelmingamountofelectricalimpulsesfromperipheralnerveendingstothebrain.”ItisbelievedthatthisunwitngbrainsGmulaGoncanhaveapotentanGdepressanteffect—ahypothesisborneoutbytheeffecGvenessofelectroshocktherapyagainstdepression.
• Thepunchlineisthatcoldshowerscanofferremarkablerelieffromdepression,withoutanyofthesideeffects,complicaGons,orassociatedcostsofprescripGonanGdepressants,electroshocktherapy,andothermedicalintervenGons.AndtheyfeelabsolutelyinvigoraGngtoo!
ColdCanDramaGcallyImproveMoodandEmoGonalState
AnothergroupofresearchersfromVirginiafoundthathydrotherapymaybeusefultotreatcancerandchronicfaGgue,aswellasbeusefulinthetreatmentofdepression(Schevchuk,2008).
ThreeprofoundeffectsofCOLDonourphysiologywhenitcomestoenergylevels…
1. InducGonofmitochondrialbiogenesis.
2. UpregulaGonofimportantmoodandenergy-boosGngneurotransminersinthebrain
3. UpregulaGonofhormonesinvolvedinenergyproducGonandincreasedlepGnsensiGvity.
COLD–EssenGaltoOpGmalEnergyandHealth
• AcolderenvironmentincreasesBATacGvityandmetabolism
• EvenleansubjectsincreaseBATandburnfat• Shiveringreleasesirisin,whichturnswhitefat
intobrownfat• Irisincorrelatestolongertelomeresandlongevity• Irisinmayexplainhowcoldthermogenesiscan
buildmuscle• IrisinincreasesinsulinsensiGvityandnutrientuptakeinto
muscle• Canirisinhelpfightcertaintypesofcancer?• BATburnsglucoseandboostsmetabolisminhumans
VastArrayofMetabolicBenefitsFromColdExposure
• Coldstressturnswhitefatinto“beige”fat• BATtherapytocombatobesity• BATburnsfatinthebloodstream• BATcontributestoonlysomeofthemetabolicincreaseofcoldstress
• BATacGvityinhumansinverselycorrelatetoobesity
• Risingenvironmentaltemperatureslinkedtoobesity?
VastArrayofMetabolicBenefitsFromColdExposure
• ColdexposureincreasesadiponecGnlevels• AdiponecGnburnsfat• AdiponecGnincreasesmitochondriaandreducesfreeradicalsin
humanskeletalmuscle• AdiponecGnincreasesmitochondriainhumanskeletalmuscle• AdiponecGnincreasesglucoseuptakeandfatburninginskeletal
muscle• AdiponecGnpushesglucoseintomuscle• AdiponecGn,obesity,insulinresistance,
andfat-burning• AdiponecGnresistanceinobesity• BrownFatsucksupglucosefromthebloodstream• Coldexposureconvertswhitefatto“beigefat”inmice• BAT-disabledmicebecomeobese
VastArrayofMetabolicBenefitsFromColdExposure
• AdiponecGnmayhelpfightcancer• LowadiponecGnandheartdisease,diabetes,systemic
inflammaGon,andmetabolicdisorder• AdiponecGn,HDL,anddiabetes• AdiponecGnasatreatmentforobesityandheart
disease• AdiponecGn,fasGng,andcircadianrhythms• AdiponecGnburnsoffglucoseandincreasesinsulinsensiGvity• AdiponecGnisproducedfrommuscleaswellasfat,inmice
ExerciseincreasesadiponecGnlevelsinobesemen• GlucoseuptakemayhelpexplainCT’s
abilitytopreserveandbuildmuscle
VastArrayofMetabolicBenefitsFromColdExposure
• Coldexposurebuildwillpower.Especiallywhendonefirstthinginthemorning.
• Doingsomethingyouaresoresistantto,everysingleday,rightwhenyouwakeup,takesalotofmentalstrength.AndoverGme,thismentalstrengthanddisciplinewillbecomeanautomatedhabitthattransferintoeveryareaofyourlife.
1)ColdExposureBuildsStrongWillPower
• Doyougetflustered,anxiousorirritableeasily?• Coldshowerscanhelp.Seriously,coldshowerstrainyour
nervoussystemtobemoreresilienttostress.• Asshowninonestudy,coldshowersactasasmallformof
oxidaGvestressonyournervoussystem.AndoverGme,thebodyadaptstothis.EssenGally,youwillbeacalm,cool,badass.ThefirstGmeyoustepinthatcoldshower,youwon’tbeabletothinkstraight,letalonebreath.Buta[eramonth,youwillbethinkingaboutyourdayinaZenlikefocusastheicecoldwaterhasnoeffectonyou.Thiswilltranslateintoeverydaylifeasyoubrushoffstressfulbullshitthatwouldtypicallyruinyourmood.
• Bodyhardening:AdapGngtoonestressorcanprovidefarreachingbenefitsagainstotherstressors.ThiscanbeviewedasanadapGontorepeatedoxidaGvestress,andispostulatedasamechanismforbodyhardening.Hardeningistheexposuretoanatural,e.g.,thermalsGmulus,resulGnginanincreasedtolerancetostress,e.g.,diseases.–Source
2)ColdExposureImprovesEmoGonalResilience
AlongwithincreasingyouradaptaGontostressfulsituaGons,theywillbuilduptheanGoxidantdefensesysteminyourmitochondria–makingyoulessstressedingeneral.
3)ColdReducesStressandOxidaGoninYourBody
Coldcanbealinlejarringatfirst,butulGmatelyitworkstoincreaseyouroxygenintake&heartrate,resulGnginanaturaldoseofenergythroughouttheday.
4)ColdIncreasesAlertness
• Oneofthemostimportantbenefitsofcoldshowersisthefactthattheyincreaseyourimmunity.
• AstudyfromEnglandshowedthattakingregularcoldshowersincreasestheamountofdiseasefighGngwhitebloodcells,comparedtothatofthosewhotakeregularhotshowers.Thehypothesiswasthattheboysanemptedtowarmit’sselfduringthecoldshower,resulGnginanincreaseinthemetabolicspeedrateandacGvaGonoftheimmunesystem.Thisthenleadstothereleaseofmorewhitebloodcells.
5)ColdImprovesImmunity
NumerousstudieshaveconfirmedthatcoldwaterimmersionsignificantlyspeedsphysicalrecoveryandrejuvenaGonfromintenseexercise.
6)ColdExposureSpeedsUpMuscleRecovery
NumerousstudieshaveconfirmedthatcoldwaterimmersioncanimpactareasofthebraincriGcalforregulaGngmoodandemoGonalstate.
7)ColdExposureRelievesDepressionandAnxiety
Obviously,anicecoldshowerisgoingtogetyouupinthemorning.Wealreadytalkedaboutthescienceshowinghowtheywillincreaseyouralertness,butbeyondthescience,thousandsofpeoplewilltellyouthatthisissimplythebestwayofgetngupandgetngenergizedfortheday.
8)TheyWakeYouUpandenergizeyourbody
• Dailymorningexposuretocold,ideallyfirstthinga[erwakingup.(Youcandoacoldbathorshoweroruseanicevestordocoldexposureoutdoorsifthatispossiblewhereyoulive).
• Startslow!Easeintoitwithawarmshowerpriortocoldone,ifnecessaryforyouatfirst.
• Takeadvantageofcoldoutdoortempsratherthanavoidingthem.
• Don’talwaysprotectyourbodywithclothesandheatersinyourhomeandcar.LetyourbodygetCOLDeverysoo[en—atleastforashortGme.
• Ifcoldisunpleasantoruncomfortable,CHANGEYOURATTITUDE!Focusonthebenefitsratherthanthepain,aswithexercise.
HottoBringtheColdIntoYourHome
Starttheshoweratacomfortablewarmtemperatureandslowlycoolthewateroverafive-minuteperioddownto68degreesFahrenheit(mildlyuncomfortable),andstayatthattemperaturefortwotothreeminutes.Youcanuseathermometertocheckthetemperatureasyougo.Thiscanbeperformedonceortwiceadayforacoupleweeks.• Eachweek,progressivelygoalinlecolder
andcolder.• WhenfirststarGngout,usea3-5minute
pre-adaptaGonwarmshowerandslowlyturnitcolderandcoldertogettothedesiredtemp.
• Note:extremecoldmayactuallyworsenmood.Noneedtogoextremewiththetemps!Don’tputyourselfinpainorshock,butyoushouldbeuncomfortable.
Dosage—STARTSLOW!
• It'sallabouttheattudeyoutakeintothis.Ifyou'rethinking"ahman...thissucks...it'ssouncomfortable...Ihatethis"thewholeGme,you'repromoGngastressreacGoninyourbody.
• YouwanttoEMBRACEit!ThinkaboutalltheposiGvephysiologicaleffectsitshavingasyou'redoingitandSMILE!EnjoytheinvigoraGngeffectsofit.ThentheinvigoraGng,energizing,andmoodli[ingeffectswillnaturallygetyouhookedonit!
It’sallabouttheATTITUDEyouhavetowardsthecold
• It’sreallynotsobad.Infact,nearlyeveryonethatadoptscoldshowersorcoldplungesasadailypracGcelearnstoloveitmuchmorequicklythanyou’dexpect.
• Ifyou’resGllapprehensive,here’ssomegoodnews:thereareevenstudiesthatdemonstratethatjust30secondsperdayofcoldwaterexposurecanhaveasignificanteffectonyouremo1onalstateonoverallwell-being.
• Allstudiesonthesubjectshowedthat68degreesFahrenheitiscoldenoughtoconfergreatbenefit,andthestudywiththemoststructuredprotocolsuggesteda5-minutepre-adaptaGonperiod—meaningthatparGcipantsgraduallyturnedthewaterfromhotto68degreesoverthecourseof5minutes.Alotofpeoplepreferthe“all-at-once”methodbecausethereseemstobesomeenergyboosGngmagicinsuddenimmersionincoldwater.
• It’sinGmidaGngnow,butgivethispracGceatryforatleastafewweeks.AsyounoGcethemoodandenergyli[ingbenefits,youmightjustgethookedsoonerthanyouexpect.
ReadytoGetCold?
HORMESIS:MajorKeytoEnhancedHealth,Longevity,andENERGY
Oneofthemostimportant—ifnotthemostimportant
—strategyforhealthandenergyenhancement.
Here’stheKEYPOINT:
ThemoreyourbodyhasbeenexposedtohormeGcstressorsandhadthechancetoadapttothem,themoreresilientyourbodybecomes.
…whichmeansthemoreopGmalyourmetabolichealthis,whichmeansthemorecellularenergyyourcellsproduceandthemoreenergyyoufeel.
TheFragile-BulletproofSpectrum
Bulletproof
Avoidanceofall
stressorsRegularsystemaGcexposuretoawidevarietyofhormeGc
stressors
HormeGcStressorsBuildTheCellularEngine
Hormesismaybethesinglemostimportantstrategytoincreaseyourmetabolichealthandboost
energylevels.
IMPORTANTPOINT…Remember,hormesisneedstobeBALANCEDwithefficientcellularregenera1on(factor#1)!
CellularRegeneraGon
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
CellularRegeneraGon
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
Whatcreatesfa1gueisthelossofoneorbothofthesetwostates.
CellularRegeneraGon
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
Whatcreatesfa1gueisthelossofoneorbothofthesetwostates.
KeyPoint:Thehiddenkeytohigherenergyisbuildingthecellular
enginethroughhormesis.
Minimal exposure
to hormetic stressors
AMPLE exposure
to hormetic stressors
Increased energy levels
Increased fitness
Resistance to disease
Increased longevity
Poor energy levels
Low fitness
Increased susceptibility to
disease
Decreased longevity
stressors
Increased energy levels
Minimal exposure
to hormetic stressors
AMPLE exposure
to hormetic stressors
Increased energy levels
Increased fitness
Resistance to disease
Increased longevity
Poor energy levels
Low fitness
Increased susceptibility to
disease
Decreased longevity
MoreMitochondria=BiggerCellEngine!
Withwelldesignedstrategies,youcangofrom500mitochondriainyourcellsto750or1,000ormore!
WhenyouincreasetheamountofmitochondriainyourcellsandtheSIZEandPOWERofthosemitochondria,youcanDOUBLEtheenergyproducingcapacityofyourcells!
SGmulaGngMitochondrialGrowth/CreaGonistheKEYtoEnergy
BiggermitochondriaandMORE
mitochondria
BiggerCellularEngine
HighercapacitytoPRODUCEENERGY!
Summary–Take-homepoints:
CellularRegeneraGon
Themagickeytohighenergylevelsinthepulsa1onandcyclingbetweenthesestates.
BuildingtheCellularEngine
CellularRegeneraGon
MOSTPEOPLEAREDEFICIENTINBOTHOFTHESETWOKEYFACTORS!
BuildingtheCellularEngine
CellularRegeneraGon
SothegoalistoaddmoreofBOTHintoyourlife!
BuildingtheCellularEngine
CellularRegeneraGon
First,youstartwiththeFOUNDATION,whichis…
BuildingtheCellularEngine
TheFoundaGonalCellRegeneraGonStrategies
1. Adequatecalories,macros,andvitamins/minerals
2. Circadianrhythmhabits3. Sleephygienehabits4. Gentlemovement5. AnG-stresshabits6. Work-rejuventaGonrhythm7. OpGmizedautophagy
CellularRegeneraGon
Thenyoustartbuildingyourcellularengineupsoitproducesmoreenergy
BuildingtheCellularEngine
Minimal exposure
to hormetic stressors
AMPLE exposure
to hormetic stressors
Increased energy levels
Increased fitness
Resistance to disease
Increased longevity
Poor energy levels
Low fitness
Increased susceptibility to
disease
Decreased longevity
ExamplesofHormesis
1. Exercise(allsubtypes)2. InterminentfasGng3. Interminentnutrientcycling4. Cold5. Heat6. Redandnear-infraredlight7. Hypoxia8. Oxygenbankruptcy9. UVlight10. XenobioGcs(caffeine,nicoGne,alcohol,manydrugs)11. Dietaryphytochemicals(xenohormeGns)
ANYtypeofexercisewillworktoincreasemitochondrialbiogenesis.Butcombina1onexerciseofbothresistanceexerciseandenduranceorHIITismosteffec1ve.
YouwillhavetodoeitherHIITorSIT.ExperimentwithdoingHIITorSITworkoutsaperoccasionalintermiEentfastsand/orthenightlyfast.
BoEomline:Areyoucurrentlysedentaryanduntrained?Areyoucurrentlyaworkoutwarriorwhoexerciseclosetoeveryday(andyou’realreadyingoodmetabolichealth)?
BoEomline:Areyoucurrentlysedentaryanduntrained)?
BoEomline:Areyoucurrentlysedentaryanduntrained)?
SummingUp:ExerciseandMitochondrialBiogenesis
YOURHOMEWORK:Here’swhatIwantyoutodo…
1. ChoosejustTWOofthefoundaGonCELLREGENERATIONstrategiestoworkon– e.g.sleepandautophagy,ornutriGonandcircadianrhythm
2. ThengettoworkontheTWOformsofhormesistointegrateintoyourlife.– IrecommendfollowingtheexerciseprotocolsIoutlinedandcoldhormesis.
FormoreinformaGonaboutmyprograms,includingTheEnergyBlueprint
Emailme:[email protected]