How the Ocean Heals Lyme Disease Integrative Lyme Solutions Academy of Comprehensive Integrative Medicine June 22, 2013, Dallas, TX Kristen T. Honey, PhD.

How the OceanHeals Lyme Disease

Integrative Lyme SolutionsAcademy of Comprehensive Integrative Medicine

June 22, 2013, Dallas, TX

Kristen T. Honey, [email protected]

Talk OutlineShare and encourage dialogue for pragmatic solutions:(1) My healing journey:

100% Lyme recovery possible with holistic approach, tenacity, resilience.



(2) Oligotherapy: Healing power of trace minerals for therapeutic support, especially bioavailable minerals from ocean.




(3) Nano-mineral treatments: Emerging science & technology for new frontiers of treatments with nano-silver and nano-gold to eradicate Lyme-related infections and symptoms.





(4) Curing Lyme:YES we can! (with patient self-care & partnership)





(4) The Lyme Cure:YES we can! (with patient self-care & partnership)

Problem solving for recoverythrough a lens of ecology & integrative systems thinking => fresh perspective on Lyme disease

Together for Lyme Solutions

Part 1: My StoryShare and encourage dialogue for pragmatic solutions:


My Healing Journey• 1999 tick bites• Decade of mystery symptoms & increasing illness• 2009 collapse with late-stage, neurological Lyme disease

From Stanford PhD… to food stamps… and back!

My Healing Journey• Healing is a full-time job• Lifestyle overhaul, which not all patients will do (diet, EMFs, etc.)• Integrated approach with emotional grief of loss & surrender


My Healing Journey• Healing is a full-time job• Lifestyle overhaul, which not all patients will do (diet, EMFs, etc.)• Integrated approach with emotional grief of loss & surrender


Note:Lyme patients can be very skilled at hiding symptoms by showing themselves only on “good” days...

…until there are not enough hours in a day to “fake it”

Volatile symptoms

Volatiledisease

My Healing Journey

What can one patient, or one practitioner, do?

Be the change!

YOU are the leader you’ve been waiting for!

Steve Schneider

My Healing Journey10 years, six months & many doctors later…

Dr. Klinghardt’s 5 levels of healing

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

Physical Body(1 PB)

Patient #1 goal:Navigate way to a medical champion, LLMD, & integrative team for healing support on ALL levels

My Healing Journey10 years, six months & many doctors later…

Dr. Klinghardt’s 5 levels of healing…although many paths to Rome for recovery

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

Physical Body(1 PB)

Successful Recovery:Mind-body-spirit work for comprehensive, holistic healing

Patient #1 goal:Navigate way to a medical champion, LLMD, & integrative team for healing support on ALL levels

My Healing JourneyModified Dr. Klinghardt’s 5 levels of healing

to reflect “biggest bang for the buck”

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

PhysicalBody(1 PB)

Objective Reality

Subj

ective

Rea

lity


plus CONTEXT MATTERS, a la Bruce Lipton

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

PhysicalBody(1 PB)


plus CONTEXT MATTERS, a la Bruce Lipton

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

PhysicalBody(1 PB)

Systems Approach on the

Shoulders of Giants:

The human body is its own ecosystem—much like the

ocean—with resilience, hysteresis, synergistic properties, and multi-system dynamics that

depend on matrix conditions.

GRATITUDE

Lynchpin:Oligotherapy w/

experimental nano-silver & nano-gold


Part 2: OligotherapyShare and encourage dialogue for pragmatic solutions:


• Healthy diet is the essential foundation of overall good health

• Today’s soil quality & food depleted of essential minerals

• Modern pollution & chronic stresses compound problem

• Mineral supplementation, in proper form, catalyzes healing

Using minerals & trace elements as catalysts to maintain physiological

functions and restore the body’s natural vitality

Oligotherapy

Oligotherapy

• Human body: 60%-70% solution of minerals & trace elements

• Our hydro-mineral composition and relative proportions are the key

• Ocean water a natural source of ALL mineral forms: Ionic, Colloidal, Chelated, Carbon-Organo-Complexed

• In 3 billion years Nature found a way to utilize ALL the elements

Minerals and Trace Elements

Cellular Life Begins

Animal Species Emerges From The Sea

“Water” Covers Earth

Begin Landmass Formation

3 Billion Years of Evolution in the Primordial OceanPRIMORDIAL OCEAN

Broader context from an evolutionary biology, systems perspective

Oligotherapy & Matrix Matters

Revolutionary

Biologist

“The only way cellular life could leave the ocean was to take the ocean with it.”

- RENÉ QUINTON“The French Darwin”

Oligotherapy & Matrix MattersBroader context from an evolutionary

biology, systems perspective

• All life is cellular

• All living things are from 50% to over 90% “biological water”

• The major elements of covalently bonded bio-molecules are C, H, N, O, P, S

• There is a universal set of small molecules: sugars, amino acids, fatty acids, phospholipids, vitamins and coenzymes

• Principal macromolecules are proteins, lipids, carbohydrates & nucleic acids

• There is a universal type of membrane - the lipid bi-layer

• The flow of energy in living things involves the formation and hydrolysis of phosphate bonds (i.e. ATP)

• The metabolic reactions of any living species is a subset of a universal network of intermediary metabolism (i.e. glycolysis, Kreb Cycle, electron transport chain)

• Every replicating cell has genome made of DNA that stores genetic information read out in a sequence of RNA & translated into proteins

• All living cells have ribosomes, which are the sites of protein synthesis

• All replicating biological systems give rise to altered phenotype due to mutated genotypes

• Reactions that proceed at appreciable rates in all living cells are catalyzed by enzymes

Seawater: Life’s ArchitectOligotherapy & Matrix

Matters

Oligotherapy

• Seawater – Complex solution of the Periodic Table and “marine factors”.

• “Amniotic Fluid” of cellular life

• Pischinger: “We now carry the Primordial Sea around within us.”

• In Stone: “Terrain is Everything”

• Isotonic the medicine – Hypertonic the nutrient

• All mineral forms: Ionic, colloidal, chelated, carbon-organo-complexed

• Re-establish elements in the milieu interieur to marine “inheritance”

The General Case: Original Quinton PlasmaPlankton Bloom Harvested – Never Heated

Disclosure: I have no financial stake in the Original Quinton company or products but recently began collaborating with their staff for on-going research, including support for my participation in the 2013 Santa Fe Institute Complex Systems program. www.original quinton.com

Composition of Quinton marine plasma near identical to human “biological terrain”

• Quinton Isotonic

• Extra-cellular fluid

• Blood plasma


“The tides are in our veins” - Robinson Jeffers

Pragmatic solution: Original Quinton

Disclosure: I have no financial stake in the Original Quinton company or products but recently began collaborating with their staff for on-going research, including support for my participation in the 2013 Santa Fe Institute Complex Systems program. www.original quinton.com

• Internal Matrix• Liquid Matrix• Internal Terrain• Biological Terrain• Internal Ocean• Milieu Interieur

• Internal Environment

“The Matrix Matters!”as we say in ecology; in medicine, it has other

names:

“The internal environment is then the primordial physiological basis of the organism, its‘liquid matrix’.” - Dr. Walter Cannon (Harvard, author of The Wisdom of the Body)


…

“The Terrain is Everything”- Claude Bernard (1850)

Still true today becausethe Primordial Ocean became our internal terrain

60-70% of us are functional fluids evolved from seawater


To support the Matrix, it’s all about rates of change… Think healing PROCESS!


Poor health is like a degraded ocean


Poor health is analogous to an ocean “Dead Zone” or atrophied estuary with algae overgrowth and depleted oxygen. With an environment this bad, not even the best doctors can save it. So, first, fix the system. Then, the fish/health can return.



My ocean health analogy = Dr. Cowden’s bathtub



Part 3: Nano-Mineral TxShare and encourage dialogue for pragmatic solutions:


Nano-Mineral TreatmentsEmerging technologies for new treatment

frontiersNanoparticles: particles <100nm diameter with new or enhanced size-dependent properties, compared with larger particles of the same material.

NOT talking man-made chemicals or futuristic bio-nanorobots


frontiersNanoparticles: particles <100nm diameter with new or enhanced size-dependent properties, compared with larger particles of the same material.

Exemplary metals with anti-microbial properties:silver, gold, copper, zinc, platinum, and palladium.

New possibilities when metals go nano…


frontiersNano-minerals 101: • Nano-structures exist naturally in nature, yet

we only recently developed technology to detect

• Ionic minerals are naturally nano-minerals • Nanotechnology modifies the surface-area-to-

volume ratios of particles• Smaller sizes, greater reactivity • Trade-off between reactivity & instability• Greater reactivity, higher potential energies

Bactericide with risk of argyria (turning blue)

Medical History of Silver• Silver used topically & internally for 6,000+

years

• Scientifically noted to purify water by 1869

• Colloidal silver used medicinally since 1860s, when coined term to describe silver suspended in a “stable, indeterminate state of matter”

Bactericide without risk of argyria (turning blue)

Ghazvini, K., MirzaHesabi, E., Akbarein, M. M., & Crémieux, A. (2008). Antibacterial activity of a malodor neutralizer containing silver nanoparticles. Navid No Journal, 42, 56-60.

NanoSilver Potential

Nanosilver kills bacteria and lower-level organisms (not mammalian cells) by wreaking havoc in the structure of membrane surfaces.

• All nanosilver is colloidal silver.

• One nanoparticle binds to multiple Borrelia Burgdorferi (Bb) cells , the spirochetal, Gram negative bacteria causing Lyme disease (Ou et al. 2005).

• Colloidal silver acts as a powerful catalyst with ability to attack one-celled organisms (i.e. bacteria, viruses, & fungi) by simultaneous ion and catalectic mechanisms (Ghazvini et al.), blocking respiration and causing the organism to suffocate and die.

Qu L. et al., Visulaizing andhesion-induced agglutination of Escherichia coli with mannosyulated nanoparticles, J. Nanosci Nanotechnol. 2005 Feb; 5(2):319-22.

(continued)NanoSilver Potential

• “Silver kills bacteria by strangling them in a warm and moist environment. Highly bioactive silver ions bind with proteins inside and outside bacterial cell membranes, thus inhibiting respiration and reproduction” (Wasif and Laga 2009).

• Nanosilver particles attack particular microbes, using species-specific mechanisms (Song et al 2006, Ruparelia 2008).

• Nanosilver prevents biofilm formation (Gibbins and Warner 2005).

Song, H. Y., Ko, K. K., Oh, I. H., & Lee, B. T. (2006). Fabrication of silver nanoparticles and their antimicrobial mechanisms. Eur Cells Mater, 11(Suppl 1), 58.

Ruparelia, J. P., Chatterjee, A. K., Duttagupta, S. P., & Mukherji, S. (2008). Strain specificity in antimicrobial activity of silver and copper nanoparticles. Acta Biomaterialia, 4(3), 707-716.

Wasif, A. I., & Laga, S. K. (2009). Use of nano silver as an antimicrobial agent for cotton. AUTEX Res. J, 9(5), 13.

Gibbins, B., & Warner, L. (2005). The role of antimicrobial silver nanotechnology. Medical Device & Diagnostic Industry Magazine, 1, 1-2.


Antimicrobial mechanisms of nanosilver include:

• Inhibition of cell wall synthesis, protein synthesis, & nucleic acid synthesis (Lara et al., 2010).

• Cell-wall “pitting” (Choi et al., 2008).

• Accumulation of silver nanoparticles in bacterial membrane (Elechiguerra et al. 2005).

• On-going investigation required to fully understand mechanisms (Marambio-Jones & Hoek 2010).

Choi, O et al. (2008). The inhibitory effect of silver nanoparticles, silver ions and silver chloride colloids on microbial growth, in Water Red, 42(12): 3066-74.

Lara, H. H., Ayala-Núnez, N. V., Turrent, L. D. C. I., & Padilla, C. R. (2010). Bactericidal effect of silver nanoparticles against multidrug-resistant bacteria. World Journal of Microbiology and Biotechnology, 26(4), 615-621.

Marambio-Jones, C., & Hoek, E. M. (2010). A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment. Journal of Nanoparticle Research, 12(5), 1531-1551.

Elechiguerra, J. L., Burt, J. L., Morones, J. R., Camacho-Bragado, A., Gao, X., Lara, H. H., & Yacaman, M. J. (2005). Interaction of silver nanoparticles with HIV-1. J nanobiotechnol, 3(6), 1-10.


Antimicrobial properties of nanosilver in a variety of medical applications including:• Topical silver widely used in wound & burn treatment to prevent

scarring & enhance healing. (Gibbins & Warner 2005).

• Silver-containing dressings to combat MRSA (Thomas 2004).

• Widely used in silver-based dressings & silver coated medicinal devices (e.g., nanogels, nanolotions, & catheters) (Rai 2009, Baratchi et al. 2009, Estevez & Erlichman 2011).

Gibbins, B., & Warner, L. (2005). The role of antimicrobial silver nanotechnology. Medical Device & Diagnostic Industry Magazine, 1, 1-2.

Rai, M., Yadav, A., & Gade, A. (2009). Silver nanoparticles as a new generation of antimicrobials. Biotechnology advances, 27(1), 76-83.

Baratchi, S., Kanwar, R. K., Khoshmanesh, K., Vasu, P., Ashok, C., Hittu, M., ... & Kanwar, J. R. (2009). Promises of nanotechnology for drug delivery to brain in neurodegenerative diseases. Current Nanoscience, 5(1), 15-25.

Estevez, A. Y., & Erlichman, J. S. (2011). Cerium Oxide Nanoparticles for the Treatment of Neurological Oxidative Stress Diseases. brain, 28, 30.

Thomas, S. (2004). MRSA and the use of silver dressings: overcoming bacterial resistance. World Wide Wounds.

Application for Lyme & Tick-Borne Coinfections

NanoSilver Potential

Few studies, if any, with patients evaluate the efficacy of nanosilver to treat Lyme, specifically, and tick borne diseases, generally.

Nonetheless, anecdotal case studies (like me) & peer-reviewed studies on general antimicrobial efficacy suggest that nanosilver can successfully treat Lyme infections—both alone and in combination with antibiotics—because of: • low risk

• high effectiveness

• microbes’ inability to evolve a silver-resistant form

Improved Antibiotic EfficacyNanoSilver Potential

Laboratory studies demonstrate a synergistic antibacterial effects between nanosilver & antibiotics (Shahverdi 2007):

• penicillin G• amoxicillin• erythromycin• clindamycin• vancomycin

May aid transport across blood-brain barrier and/or penetrate biofilms for increased antibiotic efficacy

Shahverdi, A. R., Fakhimi, A., Shahverdi, H. R., & Minaian, S. (2007). Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomedicine: Nanotechnology, Biology and Medicine, 3(2), 168-171.

Side effects: Skin rash/sores, metallic taste, thinning hair

Medical History of Gold• Gold used topically & internally for 5,000+

years

• Gold in dentistry ~4,500 years ago

• Anti-inflammatory, used to treat sore joints in 1900s, as well as arthritis in 20th Century

Extremely good catalyst, acts as a semiconductor

NanoGold Potential

Potential applications:• Rapid diagnosis technologies, including diagnosis of Lyme

disease, rickettsioses, ehrlichioses, and anaplasmosis.

• Cancer treatments without surgery, “nanobullets” that travel inside cancer cells and bind to internal structures to prevent cell division.

• Telomeres extension for increased longevity & anti-aging

• Synergisms with nanosilver for increased antimicrobial properties

• Synergisms with nanosilver to mitigate Lyme symptoms & inflammation responses, possibly prevent Herxheimer reactions

New possibilities when metals go nano…


Part 4: The Lyme CureShare and encourage dialogue for pragmatic solutions:


The Lyme Cure

100% recovery is an ACTIVE PROCESS with commitment on ALL levels

YES we can!

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

PhysicalBody(1 PB)

No silver bullet, yet people CAN heal if they believe recovery possible

The Lyme Cure

HoneyHoneyHealing.org

YES we can!

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

PhysicalBody(1 PB)

Patients & the medical community must overcome “4 min mile” barrier to full Lyme

recovery

The Lyme CureYES we can!

5th

Spirit(5 SB)

4th

Intuitive(4 IB)

3rd

Mental(3 MB)

2nd

Energy Body(2 EB)

1st

PhysicalBody(1 PB)

“We can’t solve problems by using the same kind of thinking we used when we

created them” - Albert Einstein

Infinite possibilities through innovation…


QuestionsWelcome!

Problem solving is a team effort & I’ve had a great team.

Thank you!Gratitude!

• E-IPER Department • Woods Institute for the Environment• Hopkins Marine Station, Biology Department• Terry Root & Steve Schneider, “The Patient from Hell”• Don Kennedy• Alfred Spormann• Cheryl Koopman

• Columbia University Lyme & Tick-Borne Diseases, NY

• Dr. Klinghardt & Klinghardt Academy• Foothill Chiropractic & Wellness, Los Altos, CA• Pacific Frontier Medical, Redwood City, CA• Theocentric Holistic Healing & Counseling, WPB,

FL• True North, Falmouth, ME

Stanford University

Hook, Line and Thinker by Ray Troll

(Stanford Medical School still needs Lyme education)

Medical Support

Visionary Friends• Lee Cowden, Bill Gonseaux, & Lisa Wade, ACIM• Rob Slovak, Original Quinton• Wayne Harris, Advanced BioNutritional

Research

for support from


How the Ocean Heals Lyme Disease Integrative Lyme Solutions Academy of Comprehensive Integrative Medicine June 22, 2013, Dallas, TX Kristen T. Honey, PhD.

Documents

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