This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Susan Allen-Evenson RDN, CCN Hosts Kiran Krishnan!
Premier On-line Training in Integrative and Functional Medical Nutrition Therapy (IFMNT)
• Regarding the inner and outer mucus layers inside the gut: what happens after an enema, or preparation for a colonoscopy, or even the colonoscopy procedure? Do any of these 'damage' these mucus layers? What can be done to repair it? How long does it take to repair?
• How do you rebuild the mucosa layer once it has broken down?
• Are you saying the gut microbiota regulate glucocorticoids, like cortisol, production in the gut? Is cortisol produced anywhere besides the adrenals?
• Seems like if you can only get one cytokine draw, a fed state after a typical meal would be better than fasted, as opposed to most other labs we request.
• You suggested eating Mc Donald’s meal. Would it not be better to do a typical meal a person normally eats before testing?
• Is my understanding that probiotics have to be specific to the bacteria being treated and most sold in the market aren't as such .... how do we know the exact strain before we suggest supplemental probiotic ?
• What is your opinion of Florastor(Saccharomyces boulardii)? I have patients that claim it helps a lot with stomach discomfort. Any drawbacks of using regularly?
• The elderly are more prone to c.diff, especially when in nursing homes - how could we reduce these occurrences? Elderly are more prone to SIBO as well -can we slow this from occurring?
• Is there any reason if you tolerated milk prior to having C-dif that you should avoid it when/ if you get C-dif?
• I was in a recent discussion talking about foods such as Kombuchi Tea, foods with probiotics. It was brought up that we are not really delivering probiotics because of stomach acid neutralizing. Also same theory with FOS/Inulin containing foods are not getting to large intestine. What are you seeing Kiran?
• I've read that there is more esophageal and colon cancer in Asian countries that eat a lot of fermented vegetables and fish. Why is this?
• Regionality without supplementation: are local soil bacteria important even if the food is "clean"? For instance, if I eat organic quinoa from the other side of the globe, could those soil bacteria pose an issue vs say locally grown cabbage ? How could this affect other environmental allergies? Any newer data on this that you have seen?
• Several times you mentioned glysophotase , ie., Roundup. How does this impact the microbiome and are there residual effects in commercially grown food?
• Does the less toxic version of LPS vary from best response from highest fatty cold water fish ->true triglyceride O3 supplements -> O3 supplements that are returned to triglyceride from ethyl esters -> O3 ethyl ester supplements (lowest good response)? Or is there a negligible difference along that variable of absorption & utilization by our body in relation to the LPS?
• How can we test for LPS? • How do you define high fat? What do biofilm disruptors do to LPS?
Would it likely increase endotoxins & translocation of LPS? • Does LPS affect the migrating motor complex?
• Is NAFLD just from endotoxemia or also from fructose (Robert Lustig - fructose turned into glucose in liver, glycerol is intermediate = increased triglycerides)?
• Fungal meningitis in 45yo male patient who recognizes he over-consumed carbs (especially simple carbs). Then after a month, got shingles. Any benefits to taking MegaSporeBiotic?
• To what extent is intermittent fasting negatively affected if someone is taking medication which requires a small amount of food probably up to 50 calories, mostly carbohydrate probably one and no more than 2 times during the 16 hour fast? Thank you
• You promoted intermittent fasting, eat in 8 and not for 16. I heard in another presentation where it was suggested it was not good for post menopausal women to do intermittent fasting as it negatively effected bone health. 12 hrs over night was ok. It had to do with calcium metabolism and the VDR gene. Your thoughts?
• Re: slide on what can we do? Do you recommend these strategies for those already with autoimmune diseases or for all of us attempting to prevent inflammation and autoimmune diseases?
• If you could pick 5 or 6 main strategies (since clients would resist doing all of it) what would you recommend?
• What are some of your favorite fibers to add? What recommendations do you have for those who have trouble with fiber (gas, pain, those using FODMAP diets)
• Can SCFA be taken orally? • Do you recommend taking butyrate as a supplement too?
• Is there a liquid version of antioxidants you suggested L-carnitine, lipoic acid, CoQ10 and taurine for those who have difficulty in swallowing pills, tablets, capsules?
• I see L-carnitine can be an effective therapy, but what about it's effect on GI microbes and TMAO production?
• What are recommendations for amounts of L-carnitine, lipoic acid, taurine, Zinc (and does it need to be balenaced with copper)
• Dosages for the key supplements for mucin production?
• Can you explain why the glucose is worsened in the test group vs the placebo group on the slide you showed towards the end. The one showing the difference between 30 days of probiotic treatment vs placebo in the college students.
• I have a client with dysbiosis who tried the MegaSporeBiotic and said it didn't agree with her. Any ideas as to how I can convince her to try it again?