Holotranscobalamin Laboratory : 216 Date : DD-MMM … · Date : DD-MMM-YYYY Feedback Page 1 Holotranscobalamin Distribution : 216 Laboratory : Birmingham Quality is part of the University
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Date : DD-MMM-YYYY
Feedback
Page 1
Holotranscobalamin
Distribution : 216
Laboratory :
Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust
and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK
To contact us, email [email protected] or phone us on +44 (0)121 414 7300
This Scheme is essentially web-based. We can alert you to information regarding the Scheme via email. The e-mail address (or addresses) we are currently using to contact your laboratory is shown below in red . If no e-mail address is displayed or the information shown is incorrect, please email us with an appropriate contact e-mail address as soon as possible, using the word 'feedback' in the title line.
Based on the date information you have provided, the transit time from specimen dispatch [ ] to receipt [ ] was day(s), and the subsequent time to analysis [ ] in your laboratory was day(s). (Missing values indicate dates not provided. "0 days" represents same day).
Any comments you made to us are shown below and have been acted upon where necessary
Any specific comments applicable only to laboratory are shown below
Any general comments applicable to all laboratories are shown below
*****Birmingham Quality Participant Survey*****
We are currently undertaking our annual participant survey and would very much welcome your feedback. Your comments are very important to us and will help us to improve the service we provide to you. The survey relates only to the Clinical Chemistry EQA services provided from the Birmingham Quality [UK NEQAS] centre.
A copy of the questionnaire is attached to the back of this report. It is very simple and asks only two questions:
1) What do we do well? and2) What could we do better?
We are very happy for you to submit your comments anonymously but please do provide your contact details on the form ONLY if you would like to receive a response.
Please e-mail the completed survey to [email protected] or FAX to +44 (0) 121 414 1179
Birmingham Quality is a UKAS accredited proficiency testing provider No. 7860. Please see http://www.ukas.com for full details of the accreditation status of our services
Birmingham Quality is proud to offer EQA services that adhere to the Code of Practice and have the badge of quality of UK NEQAS
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Holotranscobalamin
Distribution : 216 Date : DD-MMM-YYYY
Performance Summary Icons (click graph for details)
Page 2
Laboratory :
Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust
and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK
To contact us, email [email protected] or phone us on +44 (0)121 414 7300
For this Scheme, the Organiser is Dr. Malcolm Hamilton.
www.birminghamquality.org.uk Published at 14:36 on Friday 11 March 2016
All our time periods are 'rolling' to give you current information. You may wish to keep you own log of Calendar Year or Financial Year time points if you require 'year-end' statements for your own internal use. Any analytes with out of consensus performance will be highlighted in red and can be clicked for further details.
You have no performance data for:
You have in consensus performance for:
You have out of consensus performance for:
HoloTC
Analytical Performance over the last 6 months (rolling time window of 6 distributions)
None
None
This scheme cycle is notionally every four weeks. Analytically, we assess you over a six month time window (6 Distributions). For return rates, late and amended results we assess you over a twelve month period (12 distributions).
Participation 11 distributions out of a possible 12
Satisfactory
0 distributions from the last 11Late Returns
Amendments 0 distributions accepted from the last 11
Satisfactory
Satisfactory
Distributions
Participation and Return Rates
Rating
You can judge, in association with your IQC and other QA measures, if your current performance is a blip or part of a trend.
You have no specimen data for:
In consensus for all specimens for: HoloTC
Out of consensus for at least one specimen for:
You are not registered for:
None
Analytical Performance for specimens from distribution 216 only
None
None
The new Participation Summary page is an exciting new feature which we hope you will like. It is currently in prototype mode but will ultimately expand into having the Interpretative analytes as well as the existing ‘numerical’ analytes listed and will contain turnaround graphs etc., too.
For the moment it would be helpful if you could check the accuracy of the data presented, particularly the return-rate elements.
Many thanks, Finlay
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Date : DD-MMM-YYYY
Distribution Summary
Page 4
Holotranscobalamin
Distribution : 216
Laboratory :
Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust
and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK
To contact us, email [email protected] or phone us on +44 (0)121 414 7300
For this Scheme, the Organiser is Dr. Malcolm Hamilton.
www.birminghamquality.org.uk Published at 14:36 on Friday 11 March 2016
%biasBResult A score C scorePool CB scoreTargetSpecimen ASpecimen
NN
74.5
-6.5
216A
53.4(pmol/L)HoloTC
-0.6
216B
53.1
218(L, I, N or H)
N
220216B
HoloTC Interpretation
13.0
219220
78.8 -5.5
N
35.0216A
N
+0.7219
78218
216C N
216C
32.7
If your laboratory is outside of the acceptable limits of performance for any its rolling time-window scores (A, B or C scores), this will be indicated by a red traffic light symbol. It is the responsibility of the laboratory to undertake an internal investigation to establish the underlying cause and put in place corrective and preventive action. Please do not wait to receive a formal notification of performance from the Scheme Organiser or the National Quality Assurance Advisory Panel (NQAAP) before logging the non-conformity and, where necessary, acting upon the data contained in your report. A green traffic light merely reflects that your laboratory is performing as well as the state-of-the-art allows; it does not necessarily mean that your assay / laboratory performance is good enough clinically.
The “A scores” in this report are currently based on a ‘flat 10%’ degree of difficulty. Once we have accumulated more data points we will be able to calculate concentration-dependent degree of difficulty factors and put them in the same ‘currency’ as the A scores in other Schemes. But, for the moment, the “A scores” for HoloTC are only “proto A scores. Please see the online 'Explanation of the ABC of EQA' which may be found under the 'Centre' button on the UK NEQAS Results & Reports page. You will need your user-name and password to access this information.
All samples issued have been tested negative by standard methods for HIV, TPHA, Hepatitis B and C.
Gentamicin, penicillin and fluconazole have been added to all specimens.
Specimens for Distribution 217 will be dispatched on Monday 15 June 2015, results are due back in Birmingham by, notionally, 23:59 on Sunday 5 July 2015.
If we have entered your result as OMIT , it is because the numerical value we obtained from you was implausible for that analyte.
If we have entered your result as XPL , it is because you did not report a numerical value for that analyte, but you did provide an explanation as to why a result was not reported.
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Date : DD-MMM-YYYY
Method Summary
Page 5
Holotranscobalamin
Distribution : 216
Laboratory :
Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust
and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK
To contact us, email [email protected] or phone us on +44 (0)121 414 7300
For this Scheme, the Organiser is Dr. Malcolm Hamilton.
www.birminghamquality.org.uk Published at 14:36 on Friday 11 March 2016
arrow median
Units Method
A score
Your Submethod
A scoremedian
A scoreYour Method All labwith trend
60pmol/L
HoloTC Interpretation
Abbott Architect [AB13]
L, I, N or H
HoloTC 78 55
Our method update service is web-based and is accessed online via the 'Methods' button on the 'Results and Reports page'. You can select from a dropdown of methods or select the default option from the major manufacturer’s products*.
*If you are not using the system according to the manufacturer's instructions, please select the in-house category within your system's method principle.
A s
core
Graphic Equalizer Plot of A scoresAll laboratories
P-BWATSCR2HO
LO
0
50
100
150
200
250
300
A s
core
Method Graphic Equalizer Plot of A scoresfor your methods
P-BWATSCM2HO
LO
0
50
100
150
200
250
300
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Date : DD-MMM-YYYY
Cumulative Summary
Page 6
Holotranscobalamin
Distribution : 216
Laboratory :
Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust
and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK
To contact us, email [email protected] or phone us on +44 (0)121 414 7300
For this Scheme, the Organiser is Dr. Malcolm Hamilton.
www.birminghamquality.org.uk Published at 14:36 on Friday 11 March 2016
Human serum
220
Pool description / Treatments / Additions
216B Human serumHuman serum
Pool
219
Spec.
216A
216C
218 13.0
The B limit is +/-
Your B score is
The A limit is15.0
78
15.0
Your A score is+0.7
The C limit is
200
Your C score is
Based on the information you have provided, your reagent lot number is [] and your calibrator lot number is []. (Missing values indicate data not provided).
All methods Abbott Architect [AB13]
Specimen : 216A
24 29 34 39 44HoloTC (pmol/L)
0
2
4
6
8
10
no. o
f lab
orat
orie
s
Abbott Architect [AB13]
34.6
35.0
2
Mean
Siemens ELISA BEPIII [BE3]
n
32.6
1
In house ELISA [OO9]35.0
41
SD
7.8
35
3
2.6 7.4
2.7
CV(%)
36.1Not stated, please specify
All methods [ALTM](ALTM)
35.0
transformed bias
32.7Your result
-65
Method mean
-6.5Your specimen:
35.0
[MLTM]
Standard Uncertainty
%bias
65
0.58
Accuracy Index
Target value
Specimen : 216B
42 48 54 60 66HoloTC (pmol/L)
0
2
4
6
8
10
no. o
f lab
orat
orie
s
Abbott Architect [AB13]
53.5
53.4
2
Mean
Siemens ELISA BEPIII [BE3]
n
44.2
1
In house ELISA [OO9]53.8
41
SD
7.8
35
3
3.9 7.2
4.1
CV(%)
47.9Not stated, please specify
All methods [ALTM](ALTM)
53.8
transformed bias
53.1Your result
-6
Method mean
-0.6Your specimen:
[MLTM]
53.4
Standard Uncertainty
6
%bias
Accuracy Index
0.88
Target value
Specimen : 216C
60 69 78 87 96HoloTC (pmol/L)
0
5
10
15
20
no. o
f lab
orat
orie
s
Abbott Architect [AB13]
78.7
78.8
2
Mean
Siemens ELISA BEPIII [BE3]
n
68.4
1
In house ELISA [OO9]79.3
41
SD
7.3
35
3
5.4 6.8
5.8
CV(%)
62.9Not stated, please specify
All methods [ALTM](ALTM)
79.3
transformed bias
74.5Your result
-55
Method mean
-5.5Your specimen:
[MLTM]
78.8
Standard Uncertainty
55
%bias
Accuracy Index
1.22
Target value
B s
core
HoloTC Median and IQRs of B scores
P-BWABCBR
AB
13
-20
-15
-10
-5
0
5
10
15
20
All
Met
hod
C s
core
HoloTC Median and IQRs of C scores
P-BWABCCR
AB
13
0
5
10
15
20
All
Met
hod
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Pool
(exclusion)
[Type]
Distribution 211
28-Nov-2014
result target %bias
Distribution 212
01-Feb-2015
result target %bias
Distribution 213
01-Mar-2015
result target %bias
Distribution 214
29-Mar-2015
result target %bias
Distribution 215
03-May-2015
result target %bias
Distribution 216
07-Jun-2015
result target %bias
Distribution
result target %bias
17.5 17.08 +2.5204 26.4 21.69 +21.7 21.60207
32.3 32.7 -1.4217 32.7 35.0 -6.5218
34.6 36.6 -5.5214 42.6 37.8 +12.6211
38.3 41.6 -8.0209 48.3 52.9 -8.7203
53.1 53.4 -0.6219 61.7 58.0 +6.4 60.6210
72.5 76.8 -5.6216 74.5 78.8 -5.5220
95.6 81.3 +17.7212 102.0213
102.8 110.4 -6.9206 145.4 121.2 +19.9208
MethodmeanA scoreB scoreC score
AB13+18.1
74+1.511.1
AB13+8.9
78+3.511.4
AB13-7.9
81+1.612.7
AB13
87+3.513.8
AB13-4.2
85+3.813.3
AB13-4.2
78+0.713.0
Date : DD-MMM-YYYY
Analyte : HoloTC (pmol/L)
Page 8
Holotranscobalamin
Distribution : 216
Laboratory :
Birmingham Quality is part of the University Hospitals Birmingham NHS Foundation Trust
and provides this UK NEQAS service from PO Box 3909, Birmingham B15 2UE, UK
To contact us, email [email protected] or phone us on +44 (0)121 414 7300
For this Scheme, the Organiser is Dr. Malcolm Hamilton.
www.birminghamquality.org.uk Published at 14:36 on Friday 11 March 2016
Based on the information you have provided, your reagent lot number is [] and your calibrator lot number is []. (Missing values indicate data not provided).
A s
core
HoloTC Median and IQRs of A scores
P-BWABCAT
AB
13
0
50
100
150
200
250
300
All
Met
hod
B s
core
HoloTC Median and IQRs of B scores
P-BWABCBR
AB
13
-20
-15
-10
-5
0
5
10
15
20
All
Met
hod
B s
core
C score
HoloTC B score is +0.7 and C score is 13.0 Abbott Architect [AB13]