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Histology of NT 0708 P

May 29, 2018

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    Histology of nervous tissue

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    Able to

    identify the neurons recognize and identify the specific neurones * in the cerebrum

    in the cerebellum

    in the spinal cord

    in the ganglia recognize and identify the glial cells

    recognize and identify the special types of glialcells

    satellite / capsular cells in the ganglia Schwann cells in peripheral nerves

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    Oligodendrocytes

    Astrocytes

    Ependymal cells

    Microglial cells

    connective tissue and blood vessels

    Nervous tissue

    Schwann cells

    Capsular cells / satellite cells

    supporting cells (glial cells )nerve cells ( neurone )

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    nerve cells ( neurone )

    Gray mater

    cell body

    cerebrum

    spinal cord

    cerebellum

    axon

    ganglia

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    cell bodies of the neurons can be observed in the gray matter

    ?DRG / prevertebral / paravertebral / terminal ganglia

    ganglia

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    cell body spherical or polyhedral

    cell ( processes )

    with central nucleus,nucleoli

    Nissl substance in

    cytoplasm

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    Note:-

    - neurone

    - huge cell body,

    - prominent nucleus & nucleoli

    - basophilic granular cytoplasm

    - the presence of processes

    ( dendrites, axon )- neuroglial cells

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    nerve cells ( neurone )

    Gray mater

    cell body

    cerebrum

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    cerebrum ( N 1) characteristic feature- presence of sulci and gyri

    peripheral gray matter (cellular) central white matter (less cellular)gray matter - cell bodies of nerve cells, their processes, supporting cells, synapseswhite matter - nerve fibres, axons

    identify the neurones in gray matter

    *

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    Slide N 1 W

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    fibres

    pyramidal cells

    small cells

    pyramidal cells

    fusiform cells

    small cells

    Cerebrum / neocortex

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    Slide N 1

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    Slide N 1

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    Pyramidal cells of cerebral cortex

    Slide N 1

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    nerve cells ( neurone )

    Gray mater

    cell body

    cerebellum

    characteristic folia ( naked eye )

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    cerebellum ( N 7 )

    - gray matter 3 layers1) outer molecular layer

    ( stellate/ basket cells )

    2) middle Purkinje cell layer one layeredflask shaped cell with dendrites going into

    molecular layer, axons going into granular

    layer

    3) granular layer with granular cells

    - white matter

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    Slide N 2 - 7

    W

    piamatter

    1

    2

    3

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    1

    2

    3

    Slide N 7

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    Slide N 2 - 7

    W1

    23

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    Slide N 2 - 7

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    Slide N 2 - 7

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    Slide N 7

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    Purkinje cells of cerebellar cortex

    note :- characteristic flask shaped cell body

    small single axon ( A )

    finely branching dendritic tree ( D )

    Silver impregnation method

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    nerve cells ( neurone )

    Gray mater

    cell body

    spinal cord

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    Slide N3 11 12 13

    posterior median sulcus

    anterior median fissure

    peripheral white matter

    H-shaped central gray matter

    central canal

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    W

    G

    anterior

    posterior

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    Slide N3 11 12 13

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    Slide N3 11 12 13

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    Ganglion Spinal ganglion

    Sympathetic ganglion

    Parasympathetic ganglion

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    Slide N 5

    Spinal ganglia ( DRG )

    pseudiunipolar cell

    cell bodies (huge central nu & nucleolus)

    surrounded by satellite cells

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    Slide N 5

    aggregated cell bodies

    widely separated by nerve fibres

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    Slide N 5

    cell bodies

    satellite cells

    Note:-

    Rounded cell bodies with capsule cells ( satellite cells )

    Aggregates of cell bodies / separated by nerve fibres

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    Slide N 5

    unipolar neurones

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    Slide N 5

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    Sympathetic ganglion

    Note.

    cell bodies are evenly distributed.

    multipolar type

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    within or near the effector organ

    between two layer of smooth muscles

    Parasympathetic ganglia

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    nerve cells ( neurone )

    cell body

    axon

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    axon / nerve fibre most neurons have only one axon

    long cylindrical process

    starts from a short pyramid-shaped region, axon

    hillock plasma membrane is axolemma, content is

    axoplasm

    myelinated axon / initial segment

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    axons / peripheral nerves

    myelinated, wrapped aroundby Schwann cells

    node of Ranvier ( discontinuity

    between adjoining Schwann

    cells )

    nonmyelinated, embedded in

    Schwann cells

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    Node of Ranvier

    nerve fibre

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    Slide N 4 9

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    Longitudinal section of nerve

    - note typical wavy appearance

    Slide N 9

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    Slide N 4 9

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    Slide N 4 9

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    Slide N 4 9

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