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Histology of nervous tissue
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Able to
identify the neurons recognize and identify the specific neurones * in the cerebrum
in the cerebellum
in the spinal cord
in the ganglia recognize and identify the glial cells
recognize and identify the special types of glialcells
satellite / capsular cells in the ganglia Schwann cells in peripheral nerves
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Oligodendrocytes
Astrocytes
Ependymal cells
Microglial cells
connective tissue and blood vessels
Nervous tissue
Schwann cells
Capsular cells / satellite cells
supporting cells (glial cells )nerve cells ( neurone )
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nerve cells ( neurone )
Gray mater
cell body
cerebrum
spinal cord
cerebellum
axon
ganglia
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cell bodies of the neurons can be observed in the gray matter
?DRG / prevertebral / paravertebral / terminal ganglia
ganglia
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cell body spherical or polyhedral
cell ( processes )
with central nucleus,nucleoli
Nissl substance in
cytoplasm
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Note:-
- neurone
- huge cell body,
- prominent nucleus & nucleoli
- basophilic granular cytoplasm
- the presence of processes
( dendrites, axon )- neuroglial cells
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nerve cells ( neurone )
Gray mater
cell body
cerebrum
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cerebrum ( N 1) characteristic feature- presence of sulci and gyri
peripheral gray matter (cellular) central white matter (less cellular)gray matter - cell bodies of nerve cells, their processes, supporting cells, synapseswhite matter - nerve fibres, axons
identify the neurones in gray matter
*
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Slide N 1 W
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fibres
pyramidal cells
small cells
pyramidal cells
fusiform cells
small cells
Cerebrum / neocortex
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Slide N 1
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Slide N 1
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Pyramidal cells of cerebral cortex
Slide N 1
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nerve cells ( neurone )
Gray mater
cell body
cerebellum
characteristic folia ( naked eye )
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cerebellum ( N 7 )
- gray matter 3 layers1) outer molecular layer
( stellate/ basket cells )
2) middle Purkinje cell layer one layeredflask shaped cell with dendrites going into
molecular layer, axons going into granular
layer
3) granular layer with granular cells
- white matter
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Slide N 2 - 7
W
piamatter
1
2
3
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1
2
3
Slide N 7
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Slide N 2 - 7
W1
23
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Slide N 2 - 7
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Slide N 2 - 7
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Slide N 7
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Purkinje cells of cerebellar cortex
note :- characteristic flask shaped cell body
small single axon ( A )
finely branching dendritic tree ( D )
Silver impregnation method
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nerve cells ( neurone )
Gray mater
cell body
spinal cord
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Slide N3 11 12 13
posterior median sulcus
anterior median fissure
peripheral white matter
H-shaped central gray matter
central canal
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W
G
anterior
posterior
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Slide N3 11 12 13
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Slide N3 11 12 13
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Ganglion Spinal ganglion
Sympathetic ganglion
Parasympathetic ganglion
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Slide N 5
Spinal ganglia ( DRG )
pseudiunipolar cell
cell bodies (huge central nu & nucleolus)
surrounded by satellite cells
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Slide N 5
aggregated cell bodies
widely separated by nerve fibres
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Slide N 5
cell bodies
satellite cells
Note:-
Rounded cell bodies with capsule cells ( satellite cells )
Aggregates of cell bodies / separated by nerve fibres
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Slide N 5
unipolar neurones
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Slide N 5
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Sympathetic ganglion
Note.
cell bodies are evenly distributed.
multipolar type
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within or near the effector organ
between two layer of smooth muscles
Parasympathetic ganglia
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nerve cells ( neurone )
cell body
axon
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axon / nerve fibre most neurons have only one axon
long cylindrical process
starts from a short pyramid-shaped region, axon
hillock plasma membrane is axolemma, content is
axoplasm
myelinated axon / initial segment
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axons / peripheral nerves
myelinated, wrapped aroundby Schwann cells
node of Ranvier ( discontinuity
between adjoining Schwann
cells )
nonmyelinated, embedded in
Schwann cells
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Node of Ranvier
nerve fibre
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Slide N 4 9
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Longitudinal section of nerve
- note typical wavy appearance
Slide N 9
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Slide N 4 9
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Slide N 4 9
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Slide N 4 9
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