Highly Crosslinked UHMWPE In THR TKR ARTHROPLASTY (Polyethylene ) DR.SANDEEP AGRAWAL Consultant Orthopaedic Surgeon Agrasen Fracture Hospital Gondia Maharashtra
Highly Crosslinked UHMWPE In THR TKR ARTHROPLASTY (Polyethylene ),DR.SANDEEP AGRAWAL Agrasen Fracture Hospital Gondia Maharashtra
Jul 02, 2015
Highly Crosslinked UHMWPE
In THR TKR ARTHROPLASTY
(Polyethylene ),DR.SANDEEP AGRAWAL
Agrasen Fracture Hospital
Gondia
Maharashtra
Crucial for Revision Joint Replacemant Surgeries,
THR(Total Hip Replacement ),TKR (Total Knee Replacemant ),
Hip Knee Pain
In THR TKR ARTHROPLASTY
(Polyethylene ),DR.SANDEEP AGRAWAL
Agrasen Fracture Hospital
Gondia
Maharashtra
Crucial for Revision Joint Replacemant Surgeries,
THR(Total Hip Replacement ),TKR (Total Knee Replacemant ),
Hip Knee Pain
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Transcript
Highly Crosslinked UHMWPEIn THR TKR ARTHROPLASTY(Polyethylene )
DRSANDEEP AGRAWAL
Consultant Orthopaedic Surgeon
Agrasen Fracture Hospital
Gondia
Maharashtra
POLYETHYLENE
Timeline of Development of UHMWPE
UHMWPE
Naming of UHMWPE (HoechstCelanese 1996)
GUR (Granular UHMWPE Ruhrchemie)
ABCD HP (eg GUR 1050 GUR 4150 HP)
A 1-Germany 4-USA Texas
B 1-Ca stearate 0-none
C 2- MW=2-4million 5- MWgt4million
D 0 no meaning
HP High Purity meets the ASTM requirement (American Society for Testing and Materials)
Contemporary Highly Crosslinked UHMWPE
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
POLYETHYLENE
Timeline of Development of UHMWPE
UHMWPE
Naming of UHMWPE (HoechstCelanese 1996)
GUR (Granular UHMWPE Ruhrchemie)
ABCD HP (eg GUR 1050 GUR 4150 HP)
A 1-Germany 4-USA Texas
B 1-Ca stearate 0-none
C 2- MW=2-4million 5- MWgt4million
D 0 no meaning
HP High Purity meets the ASTM requirement (American Society for Testing and Materials)
Contemporary Highly Crosslinked UHMWPE
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Timeline of Development of UHMWPE
UHMWPE
Naming of UHMWPE (HoechstCelanese 1996)
GUR (Granular UHMWPE Ruhrchemie)
ABCD HP (eg GUR 1050 GUR 4150 HP)
A 1-Germany 4-USA Texas
B 1-Ca stearate 0-none
C 2- MW=2-4million 5- MWgt4million
D 0 no meaning
HP High Purity meets the ASTM requirement (American Society for Testing and Materials)
Contemporary Highly Crosslinked UHMWPE
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
UHMWPE
Naming of UHMWPE (HoechstCelanese 1996)
GUR (Granular UHMWPE Ruhrchemie)
ABCD HP (eg GUR 1050 GUR 4150 HP)
A 1-Germany 4-USA Texas
B 1-Ca stearate 0-none
C 2- MW=2-4million 5- MWgt4million
D 0 no meaning
HP High Purity meets the ASTM requirement (American Society for Testing and Materials)
Contemporary Highly Crosslinked UHMWPE
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Naming of UHMWPE (HoechstCelanese 1996)
GUR (Granular UHMWPE Ruhrchemie)
ABCD HP (eg GUR 1050 GUR 4150 HP)
A 1-Germany 4-USA Texas
B 1-Ca stearate 0-none
C 2- MW=2-4million 5- MWgt4million
D 0 no meaning
HP High Purity meets the ASTM requirement (American Society for Testing and Materials)
Contemporary Highly Crosslinked UHMWPE
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Contemporary Highly Crosslinked UHMWPE
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Manufacturing of UHMWPE Implants
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Irradiation in Air
MW darrrarr strength darr
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Irradiation in Inert Air
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
DurationTM Stabilization Process (1995 Howmedica)
Precursor of Highly crosslinked
Stabilization by heating 37-50 ˚C for 144 hrs
Volumetric wear 32 less than air-irradiated control
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Longevity Crosslinked PolyethylenePolyethylene is a part
crystalline part
amorphous structure
CrystallineAmorphous Free Radical
Site
Heated to Melt the Crystalline Phases
Heat
Heat
Cooled slowly to return to its original structure
Crosslink
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Comparision of Highly Crosslinked UHMWPE
AeonianTM
Bar stock
35KGyGammairradiation
25-40 kGy Gamma Sterilization
Machined after XLPack in Nitrogen
KyoceraJapanOsteonics Zimmer Zimmer
DePuy-Dupont Zimmer
Smith amp Nephew
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
The Basis for a Second-generation Highly
Crosslinked UHMWPE
First generation Highly Cross-linked (UHMWPE)
Melted highly crosslinked polyethylene may be susceptible to fatigue cracking and
Annealed highly crosslinked polyethylene may be susceptible to in vivo oxidation
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
The Basis for a Second-generation Highly
Crosslinked UHMWPE (X3 HXPE)
(X3 HXPE) uses a sequential irradiation and annealing process Mechanical strength properties preserved with the highest
survivorship in functional fatigue testing Free radical content is low and performance under
accelerated aging is the same as virgin UHMWPE Crystallinity density and tensile strength was unchanged
by oxidative challenge Volumetric wear rate very similar to metal-on-metal
articulations Wear particles were the same size as those produced from
conventional UHMWPE
Dumbleton JH DAntonio JA Manley MT Capello WN Wang A
Clin Orthop Relat Res 2006 Sep 28
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
Alternative Bearing Material seek improved function longer survivorship
Michael Piechocki Fisher J Orthopedics Today International JulyAugust 2006 p17-8
Ceramic head- on-
metal cup
(X3 HXPE)
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