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Every scientist has astoryRead his story at membercentral.aaas.org
Marine conservationist and
Kenyan coral reef expert,
Tim McClanahan, AAAS Member
Marine conservationist and
Kenyan coral reef expert,
Tim McClanahan, AAAS Member
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Certain antibody therapies havedemonstrated the potential for directing a
patientís own immune system against tumors.Further advances in this area will dependupon a detailed understanding of the tumormicroenvironment and characterization ofthe location and status of immune cells andtheir interaction with tumor cells. This willrequiremethods that provide phenotypingof immune and cancer cells combined withinformation about their spatial relationshipin tumor regions.Additionally, a deeperunderstanding of the signaling cascadesactive in immune recognition of cancers iscrucial.During this webinar,we will discussthe bringing together of multiplexedˇuorescent immunohistochemistry, advancedmicroscopy techniques, and bioinformatics,and how these are now enabling new insightsinto cancer biology and immunology.
Untangling the tumormicroenvironmentIlluminating the complex interactionsand functions of immune cells
During the webinarviewers will learn about:
ï Cutting-edge research targeting theB-cell receptor signaling pathwaythat has recently demonstratedtherapeutic promise
ï Methods that can provide indepth information on cancerphenotypes, including simultaneousimmunohistochemistry of multiplebiomarkers,multiplexed imaging,single cell quantitative analysis, andautomated phenotyping
ï How host-tumor interaction analysisin breast cancers could form the ba-sis for assays to guide therapy andmonitor response.
Speakers
Scott J. Rodig,M.D., Ph.D.Dana-Farber Cancer InstituteBoston,MA
Edward C. Stack, Ph.D.PerkinElmerHopkinton,MA
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