www.MarketResearchReports.com Hepatitis C Therapeutics in Major Developed Markets to 2019 - Outstanding Recent Approvals and Late- Stage Pipeline to Transform Clinical and Commercial Landscape Category : Pharma & Healthcare All logos and Images mentioned on this slide belong to their respective owners.
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Hepatitis C Therapeutics in Major Developed Markets to 2019 - Outstanding Recent Approvals and Late-Stage Pipeline to Transform Clinical and Commercial Landscape
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Hepatitis C Therapeutics in Major Developed Markets to 2019 - Outstanding Recent Approvals and Late-
Stage Pipeline to Transform Clinical and Commercial Landscape
Category : Pharma & Healthcare
All logos and Images mentioned on this slide belong to their respective owners.
Due to a large untreated patient pool and the recent approval of new treatments, the hepatitis C market will more than treble from $5.7 billion in 2012 to $18.6 billion by 2019, at an impressive Compound Annual Growth Rate (CAGR) of 18.5%.
The company’s new report* states that the hepatitis C market will receive this major boost with the 2013 approval of Sovaldi, which has the potential to transform the treatment algorithm for hepatitis C. Due to the clinical potential of the drug, Sovaldi will be very expensive, reaching a cost of $86,000 annually and setting a high price benchmark for future drugs.
Analyst of this report says: “Sovaldi boasts excellent tolerability and a Sustained Virologic Response rate approaching 100%, without specificity to any genotype 1. In genotypes 2 and 3, Sovaldi is administered with ribavirin alone, alleviating the need for Pegasys or Pegintron and therefore reducing the rate of adverse events associated with these two therapies. As a result, many patients who have previously deferred treatment are expected to re-enter the market and use Sovaldi.”
Additional drugs, such as Olysio, which was also approved in 2013, and daclatasvir are anticipated to compete with Sovaldi, although they are not proven to be as effective and can only be used in genotype 1 infections.
According to publisher, Sovaldi-ledipasvir and ABT-450 triple therapy will further advance the hepatitis C market and displace older drugs from 2015 onwards. This is due to the fact that these therapies can be used without peginterferon and have demonstrated 100% efficacy in genotype 1, with strong tolerability and low dosing.
“The late-stage pipeline for hepatitis C is exceptionally promising, and we expect new products to completely transform the clinical and commercial landscape during the forecast period,” Analyst concludes.
A brief introduction to hepatitis C, including the disease’s pathogenesis, risk factors and diagnosis, and detailed analyses of disease epidemiology and treatment algorithms.
In-depth analysis of the major antiviral drugs used in the treatment of hepatitis C, including analyses of their safety, efficacy, treatment patterns and strengths/weaknesses. Includes a heat map that compares marketed drugs in terms of safety and efficacy.
A comprehensive review of the pipeline for hepatitis C therapies, including individual analysis of a number of late-stage pipeline drugs that are likely to enter the market during the forecast period. The pipeline is analyzed by phase distribution, molecule type and molecular target.
In-depth clinical trial enrolment, trial duration and program failure rate analyses for each molecule type and mechanism of action. Additionally, clinical trial endpoints and certain selection criteria are analyzed in great depth. This section also includes an additional heat map regarding pipeline products, and a direct cross-analysis against currently marketed products.
Multi-scenario forecast data of the market to 2019, which takes into account the effects of the introduction of new drugs, the expiry of key patents on current drugs and the changes in disease epidemiology across the key developed markets: US, Canada, Japan, Germany, UK, France, Italy and Spain.
Discussion of the drivers and barriers for market growth.
Analysis of licensing and co-development deals occurring in the hepatitis C market.
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