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Heinz G. Floss- Biosynthesis of Ergot Alkaloids and Related Compounds

Dec 01, 2014

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Page 1: Heinz G. Floss- Biosynthesis of Ergot Alkaloids and Related Compounds
Page 2: Heinz G. Floss- Biosynthesis of Ergot Alkaloids and Related Compounds

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Biosynthesis of ergot alkaloids and related compound^ 887

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CONCLUDING REMARKS

The foregoing review has hopefully shown that thebiosynthesis of the ergoline ring system, which at onetime looked like a simple sequence of mostly non-specificreactions, involves a substantial number of very specificand rather complicated transformations. It has also

Medicinal Chemistry and Pharmacognosy, particularly ProfessorsJ. M. Cassady, C.-j. Chang, P. F. Heinstein and J. E. Robbers, andwith a number of other research groups, particularly that ofProfessor D. Groger, Halle (Saale), to all of whom I am greatlyindebted. Finally I want to thank Mrs. Lorraine Smith for herskill and patience in typing this manuscript and drawing all thestructures.

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