Heart failure
Mar 19, 2016
definition Cardiac output is inadequate for the body
function
Prognosis-82% die within 6 years after diagnosis .
Altered cardiac contractility Heart muscle disease –
cardiomyopathy ,ischemic heart disease Restricted filling –constrictive pericarditis Drugs that reduce cardiac contractility-B
blockers
Excessive preload Fluid overload-ex-NSAIDs causing fluid retention/renal
faliure/excess IVF
Mitral regurgitation
Alterations of heart rate Heart rate being too high-Tacycardia Heart rate being too low -Bradycardia Abnormal heart rate -Arrythmia
High out put heart failure Rare This results when the body demand is more so
the cardiac out put has to be maintained higher than normal. With time the heart becomes unable to maintain the cardiac output to meet the requirement
Causes include-anemia ,pregnancy ,beri beri ,hyperthyroidism
Clinical features Oedema Dyspnoea Poor exercise tolerance Fatigue Orthopnoea Paroxysmal nocturnal dyspnoea Cough with pink frothy sputum ANORREXIA
PATHOPHYSIOLOGY OF CARIDAC FAILURE Cardiac failure results in reduced body
perfusion giving rise to tiredness,reduced work capacity and loss of apatite
Fluid retention results form activation of renin angiotensin aldesterone axis
This results in edema,orthopnoea,PND Vasoconstriction and tachycardia evolves as a
compensatory mechanism which further leads to weakening of the heart
examination Looks ill Swollen lower limbs,abdomen Abnormal cardiac auscultation Weak pulse Crakles in lungs Pleural effussions
Investigations ECG ECHO-to diagnose cardiac failure and cause Chest X ray Blood investigations –FBC,TFT,SE
Management Acute heart failure is managed as a medical
emergency Chronic heart failure is managed over long
term Patient education Diagnose and treat exacerbating factors –
anemia ,hyperthyroidism
Management Avoid exercerbating factors Stop smoking Optimal nutrition and weight Less salt Drugs Final resort-heart transplant
Drugs used –pathophysiological basis Reduce preload Diuretics –reduce oedema ACE inhibitiors –to counterract activated renin angiotensin
aldesterone axis spironolactonereduce afterload Vasodilators Improve contractility Digoxin-if EF < 30%
B blockers –reduce contractility/but usage shown to improve long term out come in patients with cardiac failure
Acute heart faliure Medical emergency-breathless,weak
pulse,cyanosed,lumg crackles prop up Oxygen IV morphine and IV frusmide Find and treat the cause Inotropes