Volume 2, Number 1 March 2009 500 Helendale Rd Suite L20 Rochester, NY 14609 585.288.0890 www.rcrclinical.com UPCOMING RESEARCH STUDIES CONTACT US NOW to participate at 585.288.0890 [email protected] SMOKING Do you smoke at least 10 cigarettes a day? HIGH BP Are you taking less than 3 BP medications? FLU STUDY If you are 18-49, this study might be for you. FREE SCREEN Do you know your cholesterol numbers? Free testing! HEARTBURN Do you have heartburn at least 2 days a week? TYPE 2 DIABETES If you are taking Glucophage ® (metformin), please give us a call. A Shot to Quit Smoking? Yes. NicVAX ® , an experimental vaccine, stimulates your immune system to produce antibodies that bind to nicotine and prevent it from entering the central nervous system. Simply stated, this shot is intended to take the pleasure out of smoking. We are looking for healthy 18-65 year olds that smoke a minimum of 10 cigarettes a day, to receive 6 shots over the course of this 1 year long study. Smoking cessation counseling will also be provided. Ready to quit? Give us a call! A Vaccine that’s Not a Shot? Yes. We are testing an experimental nasal spray vaccine against seasonal influenza that is similar to FluMist ® . We need more than a hundred 18-49 year olds for this brief study that includes blood work to see if you develop antibodies against the flu. It’s OK to be in the study even if you already got a flu shot this year. Call us, and tell your friends, too! Vaccines: Researching for life without pills Research for everything from Alzheimer’s to Zoster (Shingles) Bill Gates recently gave $168 million dollars for the development of a malaria vaccine. New investigational bird flu vaccines are being tested, and the U.S. government is developing vaccines against such bioterrorism threats as anthrax, smallpox and plague. Researchers are working on an invistigational ‘universal flu shot’ effective against all strains of influenza A. Experimental vaccines to treat high blood pressure and diabetes are in development. Rochester Clinical Research is testing a new investigational vaccine to see if it may help smokers kick the habit. A full-fledged rebirth of vaccine research is at hand. Explosion of research activity . . . The market for vaccines is expected to double between 2007 and 2014. Here at RCR we conducted 7 separate clinical trials of new investigational pneumonia, seasonal flu and bird flu vaccines involving more than 700 volunteers in 2008. . . . And of potential future treatments The cutting edge of vaccine research is on finding both preventive and treatment vaccines for an ever- increasing range of maladies such as cancer, HIV, hepatitis, Alzheimer’s, asthma, psoriasis, shingles and rheumatoid arthritis. In an ironic twist, there is even an experimental cancer vaccine that is being developed from genetically engineered tobacco leaves. How will this research help others in the future? The benefits of vaccine therapies tend to last longer, and need less frequent dosing than traditional medicines. The ‘universal flu shot’ may only require one injection, replacing annual flu shots. Vaccines can also be more effective and more targeted than some traditional medicines. To treat high blood pressure, researchers are testing an experimental injectable vaccine that subjects receive every 4 months, instead of taking a daily pill. Will the day arrive when pills, tablets and capsules become obsolete? How you can help This is an exciting time in vaccine development, and we are proud to be part of moving medical science forward to confront new challenges. See two of our new vaccine studies to the right. Come be part of the solution!