haematologica Journal of the European Hematology Association Published by the Ferrata Storti Foundation Cover Figure Celebrating Volume 100 of haematologica (image created by www.somersault1824.com) (image created by www.somersault1824.com) Editorials 1 The history of Haematologica Edoardo Ascari 3 Red cells in post-genomic era: impact of personalized medicine in the treatment of anemias Achille Iolascon, et al. Review Articles 7 Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution Lesley-Ann Sutton, et al. Guideline Article 17 Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia Charlotte M. Niemeyer, et al. Articles Hematopoiesis 23 ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish Parisa Rasighaemi, et al. This article has a graphical abstract 32 Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin Isabel Dorn, et al. Bone Marrow Failure 42 Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity Michael Y. Zhang, et al. 49 Telomere length in inherited bone marrow failure syndromes Blanche P. Alter, et al. Acute Lymphoblastic Leukemia 55 Novel gene targets detected by genomic profiling in a consecutive series of 126 adults with acute lymphoblastic leukemia Setareh Safavi, et al. Volume 100, Issue 1: January 2015 Table of Contents Haematologica 2015; vol. 100 no. 1 - January 2015 http://www.haematologica.org/
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haematologicaJournal of the European Hematology Association
Published by the Ferrata Storti Foundation
Cover FigureCelebrating Volume 100 of haematologica (image created by www.somersault1824.com)(image created by www.somersault1824.com)
Editorials1 The history of Haematologica
Edoardo Ascari
3 Red cells in post-genomic era: impact of personalized medicine in the treatment of anemiasAchille Iolascon, et al.
Review Articles7 Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution
Lesley-Ann Sutton, et al.
Guideline Article17 Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia
Charlotte M. Niemeyer, et al.
ArticlesHematopoiesis23 ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish
Parisa Rasighaemi, et al. This article has a graphical abstract
32 Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin Isabel Dorn, et al.
Bone Marrow Failure42 Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity
Michael Y. Zhang, et al.
49 Telomere length in inherited bone marrow failure syndromesBlanche P. Alter, et al.
Acute Lymphoblastic Leukemia55 Novel gene targets detected by genomic profiling in a consecutive series of 126 adults with acute lymphoblastic leukemia
Setareh Safavi, et al.
Volume 100, Issue 1: January 2015Table of Contents
Haematologica 2015; vol. 100 no. 1 - January 2015http://www.haematologica.org/
Haematologica 2015; vol. 100 no. 1 - January 2015http://www.haematologica.org/
62 The negative impact of being underweight and weight loss on survival of children with acute lymphoblastic leukemiaMarissa A.H. den Hoed, et al.
70 Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia Victoria L. Bentley, et al.
Chronic Lymphocytic Leukemia77 Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy
Fabio Da Roit, et al.
Non-Hodgkin Lymphoma87 Absolute peripheral monocyte count at diagnosis predicts central nervous system relapse in diffuse large B-cell lymphoma
Hideaki Nitta, et al.
Large Granular Lymphocytic Leukemia91 The analysis of clonal diversity and therapy responses using STAT3 mutations as a molecular marker in large granular
lymphocytic leukemiaHanna L. M. Rajala, et al.
Plasma Cell Disorders100 Retrospective matched-pairs analysis of bortezomib plus dexamethasone versus bortezomib monotherapy in relapsed multiple myeloma
Meletios A. Dimopoulos, et al.
107 Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patientsCecilie Blimark, et al.
Red Cell Biology & Its Disorders124 The role of inflammation, iron, and nutritional status in cancer-related anemia: results of a large, prospective, observational study
Antonio Macciò, et al.
133 The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesisTimothy J Satchwell, et al.
Letters to the EditorLetters are available online only at www.haematologica.org/content/100/1.toc
e1 RNA sequencing reveals a unique fusion of the lysine (K)-specific methyltransferase 2A and smooth muscle myosin heavy chain 11 inmyelodysplastic syndrome and acute myeloid leukemia Mathijs A. Sanders, et al.http://www.haematologica.org/content/100/1/e1
haematologicaJournal of the European Hematology Association
Published by the Ferrata Storti Foundation
haematologicaJournal of the European Hematology Association
Published by the Ferrata Storti Foundation
e4 Biomodulatory therapy induces complete molecular remission in chemorefractory acute myeloid leukemiaSimone Thomas, et al.http://www.haematologica.org/content/100/1/e4
e7 A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4ESarit Assouline, et al.http://www.haematologica.org/content/100/1/e7
e10 Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group Mariella D’Angiò, et al.http://www.haematologica.org/content/100/1/e10
e14 Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemiaGrazia Fazio, et al.http://www.haematologica.org/content/100/1/e14
e18 Reduced dose pentostatin for initial management of hairy cell leukemia patients who have active infection or risk of hemorrhage is safe and effectiveLeslie A. Andritsos, et al.http://www.haematologica.org/content/100/1/e18
e21 Paradoxical central nervous system immune reconstitution syndrome in acquired immunodeficiency syndrome-related primary central nervous system lymphomaSarah M. Kranick, et al.http://www.haematologica.org/content/100/1/e21
e25 Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomasRebeca Manso, et al.http://www.haematologica.org/content/100/1/e25
e28 Invasive fungal infections in patients with multiple myeloma: a multi-center study in the era of novel myeloma therapies Benjamin W. Teh,et al.http://www.haematologica.org/content/100/1/e28
e32 Circadian and circannual variations in cord blood hematopoietic cell compositionSophie Servais, et al.http://www.haematologica.org/content/100/1/e32
e35 Incidence and risk factors for venous thromboembolism after laparoscopic surgery for colorectal cancerCecilia Becattini, et al.http://www.haematologica.org/content/100/1/e35
CommentsComments are available online only at www.haematologica.org/content/100/1.toc
e39 Radotinib in the treatment of chronic phase chronic myeloid leukemia patients Ahmet Emre Eskazan, et al.http://www.haematologica.org/content/100/1/e39
e40 Comment on: ‘Should clinical hematologists put their microscopes on eBay?’Shaun R. McCannhttp://www.haematologica.org/content/100/1/e40
e41 Answer to Comment on the Editorial ‘Should hematologists put their microscopes on eBay?’Mars van ‘t Veer, et al.http://www.haematologica.org/content/100/1/e41
Haematologica 2015; vol. 100 no. 1 - January 2015http://www.haematologica.org/