Financial disclosure: The study was supported by a grant from Hanita Lenses, Israel Dr. Kleinmann and Prof. Assia are consultants for Hanita Lenses, Israel Guy Kleinmann 1 , Roy Alon 2 ,Ehud I. Assia 2 [1] Kaplan Medical Center, Rehovot, Israel [2] Meir Medical Center, Kfar-Saba, Israel
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Guy Kleinmann , Roy Alon2,Ehud I. Assia · Guy Kleinmann1, Roy Alon2,Ehud I. Assia2 [1] Kaplan Medical Center, Rehovot, Israel [2] Meir Medical Center, Kfar-Saba, Israel
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Financial disclosure: The study was supported by a grant from Hanita Lenses, Israel
Dr. Kleinmann and Prof. Assia are consultants for Hanita Lenses, Israel
Guy Kleinmann1, Roy Alon2,Ehud I. Assia2
[1] Kaplan Medical Center, Rehovot, Israel [2] Meir Medical Center, Kfar-Saba, Israel
PCO is still a problem, mainly with premium IOLs
Last year we presented our preliminary favorable PCO prevention results while using the Open Capsule Device
To investigate the ability of the PID to prevent PCO using hydrophilic and hydrophobic materials and IOLs
Dimensions for rabbit trial:
Total Diameter: 11 mm
Device height: 1.5 mm
Hydrophilic and
hydrophobic rings *patent pending
Both IOLs:
Total Diameter: 13 mm
Optic diameter: 6 mm
3600 square edge
Tecnis (AMO)
Hydrophobic IOL
SeeLens AF (Hanita Lenses)
Hydrophilic IOL
36 NZW rabbit eyes were divided into six groups and implanted, after lens removal, as following:
Following tests were performed: Slit Lamp and Miyake Apple evaluation at 6 weeks
Histopathological evaluation
Hydrophobic IOL (Tecnis, AMO)
Hydrophilic IOL (SeeLens, Hanita Lenses)
6 eyes 6 eyes Control (IOL only)
6 eyes 6 eyes Hydrophilic ring (Hanita Lenses)
6 eyes 6 eyes Hydrophobic ring (Hanita Lenses)
Implantation of hydrophilic ring was easier, and can be compared to standard IOL implantation
Insertion of IOL haptics into the PID groove was not automatic and required manipulations
Ovalization due to large
diameter of the ring
The capsule remained open
Control Ring
75% less PCO compared to control
Hydrophobic IOL Hydrophilic IOL
3.1 ± 1.2 2.7 ± 1.1 Control (IOL only)
1.1 ± 0.9 0.6 ± 0.6 Hydrophilic ring**
0.6 ± 0.9 0.7 ± 0.7 Hydrophobic ring**
PCO score*:
(severe)4 (absent) to 0 [*] **P-value<0.05
Control Ring
Significant reduction in Soemmering’s ring development in test groups
Region of Soemmering’s ring coverage was manually marked and analyzed using Matlab software
Soemmering’s ring
Region of interest (bag excluding optical zone)
80% less Soemmering’s ring coverage compared to control