Great Debates in Vascular Medicine Pro: Iliac vein lesions/obstruction should always be treated PRIOR to lower extremity superficial vein ablation for patients with venous leg ulcers Mitchell Silver DO FACC FSVM RPVI Director, Center for Critical Limb Care Ohio Health Heart and Vascular Columbus, Ohio
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Great Debates in Vascular Medicine
Pro: Iliac vein lesions/obstruction should
always be treated PRIOR to lower
extremity superficial vein ablation for
patients with venous leg ulcers
Mitchell Silver DO FACC FSVM RPVI
Director, Center for Critical Limb Care
Ohio Health Heart and Vascular
Columbus, Ohio
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The Real World
Fix the Ulcer vs Fix the Patient…..
64 year old male
Venous stasis ulcer for 2 years
Venous claudication
Recurrent stasis cellulitis
Chronic leg pain/ache with standing
Recurrent swelling
Very low score on quality of life
questionnaire
>> CTA CHRONIC LEFT COMMON ILIAC VEIN OCCLUSION
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Superficial Vein Ablation
May Heal the Ulcer ???
BUT WHAT ABOUT THE PATIENT ???
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This is Simple Physiology…..
The Effect of Outflow Obstruction on Blood Flow
20% Reduction in Area 50% Reduction in Area
49% Reduction in Flow
87% Reduction in Flow
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J VASC SURG 1993;17:414-9.
“The presence of venous
outflow obstruction is a major
contributor to venous ulceration”
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Simple Physiology
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The Facts from the Evidence – Venous Ulcers
Etiology, Anatomy, Pathophysiology
Venous outflow obstructions are found in combination with
reflux in 55% of symptomatic patients.
This combination leads to the higher levels of venous
ambulatory pressure and more severe symptoms then when
either condition is present alone.
The authors recommend that when significant obstruction is
localized above the inguinal ligament, the obstruction
should be treated before any concomitant reflux.
McDaniel HB, Marston WA, Farber MA, et al. Recurrence of chronic venous ulcers on the
basis of clinical, etiologic, anatomic, and pathophysiologic criteria and air
plethysmography. J Vasc Surg. 2002;35:723-728.
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JOURNAL OF VASCULAR SURGERY
Volume 35, Number 1, 2003
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“THE MESSAGE”
Significant iliofemoral venous obstruction should be
treated, whether associated with reflux or not, in
patients with venous stasis ulceration.
When obstruction is shown with reflux, the obstruction
should be treated first.
JOURNAL OF VASCULAR SURGERY
Volume 35, Number 1, 2003
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The CONCLUSION
Iliocaval intervention alone may be sufficient
to treat patients with combined significant
reflux of both CFV and GSV.
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Let’s Be Logical…..
58 year old male with venous stasis ulcer
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INTRAVASCULAR
ULTRASOUND (IVUS)
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Let’s Be Logical…..
SUPERFICIAL
VEIN
ABLATION
WILL NOT
FIX
THE
PATIENT
VENOUS
CLAUDICATION
RECURRENT
SWELLING
SECONDARY
LYMPHEDEMA
RECURRENT
STASIS
CELLULITIS
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What About Ulcer Recurrence ?
The EVRA Trial
6,555 patients screened
6,105 patients excluded
93% of patients excluded (are results real world ?)
Ulcer recurrence was 11.4% with early intervention and
16.5% with deferred intervention before the end of one year
post randomization.
The ESCHAR Trial
Ulcer recurrence was 9% at 1 year, 20% at 2 years, and 29%
at 3 years in the intervention group.
Ulcers recurred significantly more in patients with deep