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Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Jan 23, 2020

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Page 1: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes
Page 2: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glycans impact many fields

Page 3: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Mas

s-Sp

ec a

ppro

ache

s for

cha

ract

erizi

ng a

nd

quan

tifyi

ng g

lyca

ns

Page 4: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Mas

s-Sp

ec a

ppro

ache

s for

cha

ract

erizi

ng a

nd

quan

tifyi

ng g

lyca

ns

Page 5: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Prof

iling

gly

cans

in c

ompl

ex m

ixtu

res

Page 6: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Prof

iling

gly

cans

in c

ompl

ex m

ixtu

res

Page 7: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Prof

iling

gly

cans

in c

ompl

ex m

ixtu

res

Page 8: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Nov

el Te

chni

ques

for R

elea

sing

Glyc

ans

Page 9: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glyc

an b

indi

ng p

rote

ins f

or d

etec

ting

and

enric

hing

gly

cans

Page 10: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glyc

an b

indi

ng p

rote

ins f

or d

etec

ting

and

enric

hing

gly

cans

Page 11: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glyc

an b

indi

ng p

rote

ins f

or d

etec

ting

and

enric

hing

gly

cans

Page 12: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Dete

ctin

g ch

ange

s in

the

bios

ynth

esis

of

glyc

ans

Page 13: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Dete

ctin

g ch

ange

s in

the

bios

ynth

esis

of

glyc

ans

Page 14: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Bioi

nfor

mat

ics T

ools

for S

tudy

ing

GLyc

ans

Page 15: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Bioi

nfor

mat

ics T

ools

for S

tudy

ing

GLyc

ans

Page 16: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Bioi

nfor

mat

ics T

ools

for S

tudy

ing

GLyc

ans

Page 17: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Chem

ical

Pro

bes

Page 18: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Chem

ical

Pro

bes

Page 19: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Stud

ying

Pro

teog

lyca

ns

Page 20: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Prof

iling

gly

cans

in c

ompl

ex m

ixtu

res

Page 21: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glyc

an b

indi

ng p

rote

ins f

or d

etec

ting

and

enric

hing

gly

cans

Page 22: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glyc

an b

indi

ng p

rote

ins f

or d

etec

ting

and

enric

hing

gly

cans

Page 23: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Glyc

an b

indi

ng p

rote

ins f

or d

etec

ting

and

enric

hing

gly

cans

Page 24: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Stud

ying

Pro

teog

lyca

ns

Page 25: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Man

ipul

atin

g GL

ycan

s

Page 26: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Man

ipul

atin

g GL

ycan

s

Page 27: Glycans impact many fields - commonfund.nih.gov · SAP Tract prx3 Lung sp.A Liver Labeled mGAPs streptavidin bead Microbe sorting via FACS and microbiome profiling Imaging microbes

Want to Learn More: https://commonfund.nih.gov/glycoscience