Institute for Biomedical Informatics Genomics and Computational Biology Graduate Group 2017 Annual Retreat June 8 • 8:00 AM – 5:00 PM The College of Physicians of Philadelphia Mutter Museum 19 South 22nd Street Philadelphia, PA 19103 For more information, please contact Maureen Kirsch [email protected] Institute for Biomedical Informatics Many thanks to our sponsors! The Children’s Hospital of Philadelphia Department of Biomedical and Health Informatics The Children’s Hospital of Philadelphia Research Institute Department of Genetics, Perelman School of Medicine 8:00 AM Breakfast 9:00 AM Opening remarks 9:15 AM Melissa Wilson Sayres, Keynote Lecture Assistant Professor of Genomics, Evolution, and Bioinformatics, Arizona State University Sex-based Genome Evolution 10:15 AM Alex Amlie-Wolf GCB Student, Wang Lab Integrative analysis identifies immune-related enhancers and lncRNAs perturbed by genetic variants associated with Alzheimer’s disease 10:40 AM Eric Joyce Assistant Professor of Genetics High-throughput imaging and analysis of 3D genome organization Coffee break 11:35 AM Ian Mellis MD-PhD GCB Student, Raj Lab Determining and inducing gene expression patterns underlying cell identity 12:00 PM William La Cava Postdoctoral Researcher, Moore Lab A general feature engineering wrapper for learning biomedical data representations Lunch and poster session 2:00 PM Laura Almasy Professor of Genetics Variance component approaches for complex trait genetics 2:25 PM Matthew Breitenstein Instructor in Informatics Translational bioinformatics: molecular signal detection in cancer pharmacoepidemiology 2:50 PM Katie Siewert GCB Student, Voight Lab Genetic correlation and causal inference analyses for migraine headache Coffee break 3:45 PM Steven Salzberg, Plenary lecture Bloomberg Distinguished Professor of Biomedical Engineering, Computer Science and Biostatistics, Johns Hopkins University Transcriptome Assembly: Computational Challenges of Next-Generation Sequence Data 4:45 PM Reception