Genomics and Pediatric Cancers
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Genomics and Pediatric Cancers
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Outline
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Childhood cancer
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Mortality rates
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Pediatric cancers
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Gene expression
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Gene expression
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Gene expression
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Human genome
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Genomic research
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Gene measurement
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First generation tools
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Microarrays
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Next-generation sequencing
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Massively Parallel Sequencing
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Genomic Alterations
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Genomic Alterations
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Properties
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Cancer Genomes
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Clinical Vignette
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Wilms tumor
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Cancer diagnosis
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Diagnosis
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Rearrangement
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Pediatric cancer mutations
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Clinomics for precision medicine
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Study design
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Mutations
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Multi-omics integrated landscape
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Fusion genes
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Somatic mutations
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Match criteria
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Tumor mutations
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Germline mutations
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Summary
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Future Trials
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ClinOmics program
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Operational goals
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Exome vs. Panel
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Clinomica Wesite
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QC report
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QC report
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Mutation view
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Conclusions
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Acknowledgements
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