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Genomic Medicine in the VHA Laurence Meyer, MD, PhD May 28, 2013
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Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Aug 21, 2018

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Page 1: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Genomic Medicine in the VHA

Laurence Meyer, MD, PhD May 28, 2013

Page 2: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

VHA

• 23.4 million veterans alive – About 7 million veterans will receive care in 2011 – About 8 million enrolled – Over 60 million yearly visits

• 153 medical centers – 1400 total sites

• All centers use the same medical record system – About 180 separate servers

Page 3: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Genetic Medicine at the VA • Genetic Medicine Program Advisory Committee

– Established 3/16/06, charter dated 2/12/08 • “Goal of using genetic information to optimize

clinical care of veterans, and enhance the study and development of diagnostic tests and treatments for diseases of particular relevance to veterans.”

• “Recommending processes and goals for the development of a VA genomic medicine...and…approaches by which research results can be incorporated into routine medical care.”

Page 4: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Regional Centers and Service

• Many providers deliver genetic care • Many complex genetic cases referred to

academic affiliates • Four VAs with specific genetic clinics

– Los Angeles has center for that region

• Workload only captured 2 years ago as genetic service

Page 5: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Research and Clinical Genomics

• Research initiated genomics as a priority – Individual investigator initiated awards – Large Cooperative studies – Genomic medicine program

• Million Veteran Program: MVP – Informed by surveys of veterans

• Clinical program lagged

Page 6: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

National Clinical Genomic Medicine Service (GMS)

• Memorandum of September 2010 established a process for credentialing and privileging telehealth providers between VAs.

• Hired and locally credentialed first VA clinical Genetic Counselor January 2011

• March 2011 started first Memorandum of Understanding (MOU) to to provide telegenetic service at a remote VA

Page 7: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Telehealth In the VA • Goal: 50% of all encounters by 2020

– Reaches veteran closer to their site – Allows level of care not usually available – Usually between VAMC and CBOCs

• Price and Elko

• Other programs- between medical centers – ICU

• Genomics- has used to create a centralized service based in Salt Lake City

Page 8: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Where we WERE

Page 9: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Where we are GOING

Page 10: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

GMS consult set-up

Patient view of GC

GC view of patient

Page 11: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

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4th QTR FY11 1st QTR FY12 2nd QTR FY12 3rd QTR FY12 4th QTR FY12 1st QTR FY13 2nd QTR FY13

Genomic Workload (21 Months)

Progress Notes

Encounters

Uniques

Page 12: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

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4th QTR FY11 1st QTR FY12 2nd QTR FY12 3rd QTR FY12 4th QTR FY12 1st QTR FY13 2nd QTR FY13 ToDate

MOU & TSA Increase by QTR

MOU's & TSA's Sent ToVA Patient ReferringSites

MOU's & TSA's Signed

Page 13: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Telephone18%

CVT37%

e-consults34%

non-responders

11%

Non-Local Delivery Modality

Page 14: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

PCP/Womens35%

GI33%

Heme/Onc15%

Pathology3% Other specialties

14%

Referral Source

Page 15: Genomic Medicine in the VHA - National Human … · development of a VA genomic medicine ... – Large Cooperative studies – Genomic medicine program • Million Veteran Program:

Need and Gaps

• Integration with EMR – Electronic access to labs - structured – Family history - structured – Computer decision support

• Processes for evaluation of clinical utility in our population - large scale