Genomic activities Genomic activities for Glossina at for Glossina at SANBI SANBI 2006 2006 Win Hide, Mario Jonas and the SANBI team, Win Hide, Mario Jonas and the SANBI team, University of the Western Cape University of the Western Cape South Africa South Africa
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Genomic activities for Glossina at SANBI 2006 Win Hide, Mario Jonas and the SANBI team, University of the Western Cape South Africa.
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Genomic activities for Genomic activities for Glossina at SANBIGlossina at SANBI
20062006
Win Hide, Mario Jonas and the SANBI team, Win Hide, Mario Jonas and the SANBI team, University of the Western CapeUniversity of the Western Cape
South AfricaSouth Africa
International Annotation and SANBI•USA : Promoter element signatures and anatomically restricted expression
with the Allen Institute for Brain Science
•USA : NIH funded Baboon cDNA annotation project
•USA: NIH funded HIV genome annotation
•Japan: H-INV human cDNA clustering and annotation with the Genome
Network Project (GNP), Japan
•Japan: Fantom3 consortium, Japan, with the role of promoter annotation
and gene expression annotation between mouse and man
•Japan: GNP and Fantom4 we perform data integration, analysis, and
comparison of gene expressoin between mouse and human to include
determination of promoter element signatures related to expression states.
•Heikki Lehvaslaiho - SANBI•Win Hide - SANBI•Mario Jonas - SANBI•Michael Gaunt - LSHTM/SANBI•Alan Christoffels - TEMASEK•Todd Taylor - RIKEN•Matt Berriman - SANGER•Christiane Hertz-Fowler - SANGER•Michael Ashburner - U Cambridge•Suzi Lewis - Berkeley•Kim Worley - Baylor•Dan Lawson - SANGER
Annotation
•Need a realistic annotation strategy for the vector.•How will data become available.? •How will it initially become annotated•How will it be re-annotated?•How will it be exploited in the African context to
result in control?
Learning from the past
•Drosophila genome project
• Global view
•specific annotation improvements could be targetted fopr IGGI
•Select key gene families and target the BAC sequencing so that more specific sequence analyses can be carried out in parallel